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Most cited papers from Age UK

What are the most cited papers from Age UK?

The most cited paper from Age UK is "A tutorial on particle filters for online nonlinear/non-Gaussian Bayesian tracking" (M.S. Arulampalam, Simon R. Maskell, Neil Gordon et al., 2002), with 11,594 citations. Next come "FinnGen provides genetic insights from a well-phenotyped isolated population" (4,362) and "The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models" (3,190).

Showing 50 of 60 papers. Every paper with more than 357 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A tutorial on particle filters for online nonlinear/non-Gaussian Bayesian tracking M.S. Arulampalam, Simon R. Maskell, Neil Gordon et al. · IEEE Transactions on Signal Processing 2002 11,594
2 FinnGen provides genetic insights from a well-phenotyped isolated population Mitja Kurki et al. · Nature Open access169 authors 18 Jan 2023 4,362
3 The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models Michael Hucka et al. · Bioinformatics Open access 28 Feb 2003 3,190
4 The support of human genetic evidence for approved drug indications Matthew R. Nelson, Hannah Tipney, Jeffery L. Painter et al. · Nature Genetics 29 Jun 2015 1,812
5 Plasma proteomic associations with genetics and health in the UK Biobank Benjamin B. Sun et al. · Nature Open access 4 Oct 2023 1,716
6 Organic synthesis provides opportunities to transform drug discovery David C. Blakemore, Luis C. Misal Castro, Ian Churcher et al. · Nature Chemistry 22 Mar 2018 1,554
7 An analysis of the attrition of drug candidates from four major pharmaceutical companies Michael J. Waring, John E. Arrowsmith, Andrew R. Leach et al. · Nature Reviews Drug Discovery Review 19 Jun 2015 1,467
8 Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling Joanna C. Betts, Pauline T. Lukey, Linda C. Robb et al. · Molecular Microbiology Open access Feb 2002 1,426
9 Catalytic in vivo protein knockdown by small-molecule PROTACs Daniel P. Bondeson et al. · Nature Chemical Biology Open access 10 Jun 2015 1,365
10 Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy Alessandra Biffi et al. · Science Open access 12 Jul 2013 1,207
11 Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS Maureen P. Martin, Xiaojiang Gao, Jeong-Hee Lee et al. · Nature Genetics 22 Jul 2002 1,196
12 Expanding GSK's solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry Richard K. Henderson, Concepción Jiménez‐González, David J. C. Constable et al. · Green Chemistry 2011 1,140
13 Mapping the human genetic architecture of COVID-19 COVID-19 Host Genetics Initiative et al. · Nature Open access3,896 authors 8 Jul 2021 1,130
14 Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis Frieda A. Koopman, Sangeeta S. Chavan, S. Miljko et al. · Proceedings of the National Academy of Sciences Open access 5 Jul 2016 1,049
15 Updating and further expanding GSK's solvent sustainability guide Catherine M. Alder, John D. Hayler, Richard K. Henderson et al. · Green Chemistry 2016 1,045
16 Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics Joanne T. Brindle, Henrik Antti, Elaine C. Holmes et al. · Nature Medicine 25 Nov 2002 997
17 A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response Laurens Kruidenier et al. · Nature Open access 27 Jul 2012 975
18 Actively personalized vaccination trial for newly diagnosed glioblastoma Norbert Hilf et al. · Nature 19 Dec 2018 954
19 Resistin is expressed in human macrophages and directly regulated by PPARγ activators Lisa Patel, Amy C Buckels, Ian J. Kinghorn et al. · Biochemical and Biophysical Research Communications 2003 928
20 Proteomics: quantitative and physical mapping of cellular proteins Walter P. Blackstock, Malcolm Weir · Trends in biotechnology Review Mar 1999 873
21 Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases Jie Zheng et al. · Nature Genetics Open access 7 Sep 2020 854
22 Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation Huw D. Lewis et al. · Nature Chemical Biology Open access 26 Jan 2015 792
23 Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics Maya Ghoussaini et al. · Nucleic Acids Research Open access 17 Sep 2020 717
24 HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials Daniel I. Swerdlow et al. · The Lancet Open access133 authors 24 Sep 2014 713
25 An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People Matthew R. Nelson et al. · Science Open access 18 May 2012 707
26 Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data Michael Vaclav Holmes et al. · BMJ Open access155 authors 10 Jul 2014 689
27 Cleavable linkers in antibody–drug conjugates Jonathan D. Bargh, Albert Isidro‐Llobet, Jeremy S. Parker et al. · Chemical Society Reviews Review 2019 659
28 Membranes for the dehydration of solvents by pervaporation Peter D. Chapman, Teresa A.C. Oliveira, Andrew Guy Livingston et al. · Journal of Membrane Science 10 Mar 2008 647
29 Exome sequencing and characterization of 49,960 individuals in the UK Biobank Cristopher V. Van Hout et al. · Nature Open access 21 Oct 2020 637
30 A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome Akram Khan, Cody Benthin, Brian R. Zeno et al. · Critical Care Open access 5 Sep 2017 634
31 Financial Strain over the Life Course and Health among Older Adults Joan R. Kahn, Leonard I. Pearlin · Journal of Health and Social Behavior Mar 2006 632
32 International Union of Pharmacology. XLVI. G Protein-Coupled Receptor List Steven M. Foord, Tom I. Bonner, Richard R. Neubig et al. · Pharmacological Reviews 24 May 2005 620
33 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries Nick R. G. Shrine et al. · Nature Genetics Open access110 authors 25 Feb 2019 615
34 Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology Manuel A. R. Ferreira et al. · Nature Genetics Open access 30 Oct 2017 585
35 Open Targets Platform: supporting systematic drug–target identification and prioritisation David Ochoa et al. · Nucleic Acids Research Open access 11 Nov 2020 577
36 Emerging therapeutic opportunities for integrin inhibitors Robert J. Slack, Simon J. F. Macdonald, James A. Roper et al. · Nature Reviews Drug Discovery ReviewOpen access 17 Sep 2021 574
37 Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer’s disease risk genes Jeremy Schwartzentruber, Sarah Cooper, Jimmy Z. Liu et al. · Nature Genetics Open access 15 Feb 2021 572
38 Efficacy of treating pain to reduce behavioural disturbances in residents of nursing homes with dementia: cluster randomised clinical trial Bettina Sandgathe Husebo, Clive G. Ballard, Reidun Karin Norheim Myhre Sandvik et al. · BMJ Open access 15 Jul 2011 570
39 Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor Kimberly Burns, Jonathan Clatworthy, Laurence Martin et al. · Nature Cell Biology 10 May 2000 565
40 Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort Dominick E. Shaw et al. · European Respiratory Journal Open access 10 Sep 2015 564
41 Open Targets: a platform for therapeutic target identification and validation Gautier Koscielny et al. · Nucleic Acids Research Open access 3 Nov 2016 553
42 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data Ioanna Tachmazidou et al. · Nature Genetics Open access 21 Jan 2019 551
43 Open Targets Platform: new developments and updates two years on Denise Carvalho‐Silva, Andrea Pierleoni, Miguel Pignatelli et al. · Nucleic Acids Research Open access 26 Oct 2018 537
44 Pursuing the leadlikeness concept in pharmaceutical research Mike Hann, Tudor Ionel Oprea · Current Opinion in Chemical Biology Review 8 May 2004 515
45 The 3D OrbiSIMS—label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power Melissa K. Passarelli, Alexander Pirkl, Rudolf Moellers et al. · Nature Methods Open access 13 Nov 2017 482
46 Effects of acute subcutaneous nicotine on attention, information processing and short-term memory in alzheimer's disease Gemma Jones, Barbara Jacquelyn Sahakian, Roy Levy et al. · Psychopharmacology Sep 1992 478
47 Site-selective modification strategies in antibody–drug conjugates Stephen J. Walsh, Jonathan D. Bargh, Friederike M. Dannheim et al. · Chemical Society Reviews ReviewOpen access 10 Dec 2020 460
48 HIBAG—HLA genotype imputation with attribute bagging Xiuwen Zheng, Judong Shen, Charles J. Cox et al. · The Pharmacogenomics Journal Open access 28 May 2013 458
49 A green chemistry perspective on catalytic amide bond formation Marco T. Sabatini, Lee T. Boulton, Helen F. Sneddon et al. · Nature Catalysis 4 Jan 2019 436
50 Finding the sweet spot: the role of nature and nurture in medicinal chemistry Michael M. Hann, György Miklós Keserű · Nature Reviews Drug Discovery Review 30 Apr 2012 421

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.