| 1 |
The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans
David M. Tobin, Jay C. Vary, John P. Ray et al. · Cell
Open access |
Mar 2010 |
541 |
| 2 |
Comparative genomic and phylogeographic analysis of Mycobacterium leprae
Marc Monot et al. · Nature Genetics
Open access |
Nov 2009 |
396 |
| 3 |
Antimicrobial resistance in leprosy: results of the first prospective open survey conducted by a WHO surveillance network for the period 2009–15
Emmanuelle Cambau et al. · Clinical Microbiology and Infection
Open access138 authors |
Mar 2018 |
176 |
| 4 |
Human TLR1 Deficiency Is Associated with Impaired Mycobacterial Signaling and Protection from Leprosy Reversal Reaction
Elizabeth Ann Misch, Murdo Macdonald, Chaman Ranjit et al. · PLoS neglected tropical diseases
Open access |
6 May 2008 |
143 |
| 5 |
Development of an in-house loop-mediated isothermal amplification (LAMP) assay for detection of Mycobacterium tuberculosis and evaluation in sputum samples of Nepalese patients
Basu Dev Pandey, Ajay Poudel, Tomoko Yoda et al. · Journal of Medical Microbiology
|
18 Mar 2008 |
127 |
| 6 |
Association of TNF, MBL, and VDR polymorphisms with leprosy phenotypes
Bishwa R. Sapkota, Murdo Macdonald, William R. Berrington et al. · Human Immunology
Open access |
21 Jul 2010 |
107 |
| 7 |
ENLIST 1: An International Multi-centre Cross-sectional Study of the Clinical Features of Erythema Nodosum Leprosum
Stephen L. Walker, Marivic F. Balagon, Joydeepa Darlong et al. · PLoS neglected tropical diseases
Open access |
9 Sep 2015 |
106 |
| 8 |
Dihydropteroate Synthase of Mycobacterium leprae and Dapsone Resistance
Diana Lynn Williams, Laynette Spring, Eugene B. Harris et al. · Antimicrobial Agents and Chemotherapy
Open access |
Jun 2000 |
101 |
| 9 |
Common Polymorphisms in theNOD2Gene Region Are Associated with Leprosy and Its Reactive States
William R. Berrington, Murdo Macdonald, Saraswoti Khadge et al. · The Journal of Infectious Diseases
Open access |
29 Mar 2010 |
97 |
| 10 |
Risk factors for erythema nodosum leprosum.
Rakesh Manandhar, Joe Lemaster, PAUL W. ROCHE · PubMed
|
Sep 1999 |
89 |
| 11 |
T-Cell Regulation in Lepromatous Leprosy
Kidist Bobosha, Louis Wilson, Krista E. van Meijgaarden et al. · PLoS neglected tropical diseases
Open access |
10 Apr 2014 |
86 |
| 12 |
Skin disease is common in rural Nepal: results of a point prevalence study
SL Walker, Mahesh Shah, Virginia G. Hubbard et al. · British Journal of Dermatology
|
17 Aug 2007 |
85 |
| 13 |
Development of a whole blood assay to measure T cell responses to leprosy: a new tool for immuno-epidemiological field studies of leprosy immunity
Rosemary E. Weir, Aric Morgan, Warwick J. Britton et al. · Journal of Immunological Methods
|
Nov 1994 |
77 |
| 14 |
Selection of Antigens and Development of Prototype Tests for Point-of-Care Leprosy Diagnosis
Malcolm S. Duthie, Greg C. Ireton, Ganga V. Kanaujia et al. · Clinical and Vaccine Immunology
Open access |
21 Aug 2008 |
72 |
| 15 |
Risk factors for type-1 reactions in borderline leprosy patients
PAUL W. ROCHE, W. J. Theuvenet, Warwick J. Britton · The Lancet
|
Sep 1991 |
69 |
| 16 |
Effective Treatment of Erythema Nodosum Leprosum with Thalidomide Is Associated with Immune Stimulation
Patrick A. J. Haslett, PAUL W. ROCHE, Cynthia Ruth Butlin et al. · The Journal of Infectious Diseases
Open access |
16 Nov 2005 |
68 |
| 17 |
Diagnosis and Treatment of Leprosy Reactions in Integrated Services - The Patients' Perspective in Nepal
Sonia F. Raffe, Min B. Thapa, Saraswoti Khadge et al. · PLoS neglected tropical diseases
Open access |
7 Mar 2013 |
64 |
| 18 |
Clinical outcomes in a randomized controlled study comparing azathioprine and prednisolone versus prednisolone alone in the treatment of severe leprosy type 1 reactions in Nepal
Sharon Marlowe, Rachel A. Hawksworth, Cynthia Ruth Butlin et al. · Transactions of the Royal Society of Tropical Medicine and Hygiene
|
20 Jul 2004 |
63 |
| 19 |
Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal
Saraswoti Khadge et al. · BMC Infectious Diseases
Open access |
28 Oct 2015 |
63 |
| 20 |
A leprosy clinical severity scale for erythema nodosum leprosum: An international, multicentre validation study of the ENLIST ENL Severity Scale
Stephen L. Walker et al. · PLoS neglected tropical diseases
Open access |
3 Jul 2017 |
55 |
| 21 |
Diagnosis and impact of neuropathic pain in leprosy patients in Nepal after completion of multidrug therapy
Han Siong Toh, Jeni Maharjan, Ruby Thapa et al. · PLoS neglected tropical diseases
Open access |
2 Jul 2018 |
54 |
| 22 |
A Phase Two Randomised Controlled Double Blind Trial of High Dose Intravenous Methylprednisolone and Oral Prednisolone versus Intravenous Normal Saline and Oral Prednisolone in Individuals with Leprosy Type 1 Reactions and/or Nerve Function Impairment
Stephen L. Walker, PETER G. NICHOLLS, Sushmita Dhakal et al. · PLoS neglected tropical diseases
Open access |
12 Apr 2011 |
46 |
| 23 |
A Postgenomic Approach to Identification ofMycobacterium leprae-Specific Peptides as T-Cell Reagents
Hazel M. Dockrell, Shweta Brahmbhatt, Brian D. Robertson et al. · Infection and Immunity
Open access |
Oct 2000 |
45 |
| 24 |
Insights from animal models on the immunogenetics of leprosy: a review
Linda B. Adams, Maria T. Peña, Rahul Sharma et al. · Memórias do Instituto Oswaldo Cruz
Open access |
Dec 2012 |
45 |
| 25 |
Mortality due to dapsone hypersensitivity syndrome complicating multi-drug therapy for leprosy in Nepal
Bijay Pandey, Kanchha Shrestha, Justin S. Lewis et al. · Tropical Doctor
|
Jul 2007 |
45 |
| 26 |
High levels of inflammatory cytokines are associated with poor clinical response to steroid treatment and recurrent episodes of type 1 reactions in leprosy
Rakesh Manandhar, Nripesh Man Shrestha, Cynthia Ruth Butlin et al. · Clinical & Experimental Immunology
Open access |
May 2002 |
44 |
| 27 |
Delay in presentation and start of treatment in leprosy: experience in an out-patient clinic in Nepal
LINDA M. ROBERTSON, PETER G. NICHOLLS, R Butlin · Leprosy Review
Open access |
2000 |
41 |
| 28 |
An assessment of the reported impact of the COVID-19 pandemic on leprosy services using an online survey of practitioners in leprosy referral centres
Barbara de Barros, Saba M. Lambert, Edessa Negera et al. · Transactions of the Royal Society of Tropical Medicine and Hygiene
Open access |
17 May 2021 |
40 |
| 29 |
Operational value of serological measurements in multibacillary leprosy patients: clinical and bacteriological correlates of antibody responses.
PAUL W. ROCHE, Warwick J. Britton, S S Failbus et al. · PubMed
|
Sep 1990 |
40 |
| 30 |
Effectiveness of 32 versus 20 weeks of prednisolone in leprosy patients with recent nerve function impairment: A randomized controlled trial
Inge Wagenaar, Erik B. Post, Wim Brandsma et al. · PLoS neglected tropical diseases
Open access |
4 Oct 2017 |
38 |
| 31 |
A preliminary investigation of the responsiveness or otherwise of patients and staff of a leprosy hospital to groups of shared or species specific antigens of mycobacteria
J. L. Stanford, P. Nye, G.A.W. Rook et al. · Leprosy Review
Open access |
1981 |
38 |
| 32 |
Interventions for Stigma Reduction–Part 1: Theoretical Considerations
Hugh Alistair Cross, Miriam L. Heijnders, Ajit K. Dalal et al. · Disability CBR & Inclusive Development
Open access |
15 Feb 2012 |
38 |
| 33 |
Whole blood RNA signatures in leprosy patients identify reversal reactions before clinical onset: a prospective, multicenter study
Maria Tió‐Coma et al. · Scientific Reports
Open access |
29 Nov 2019 |
37 |
| 34 |
Serological monitoring of the response to chemotherapy in leprosy patients.
PAUL W. ROCHE, Warwick J. Britton, S. S. Failbus et al. · PubMed
|
Mar 1993 |
37 |
| 35 |
Real-Time PCR and High-Resolution Melt Analysis for Rapid Detection of Mycobacterium leprae Drug Resistance Mutations and Strain Types
Wei Li, Masanori Matsuoka, Masanori Kai et al. · Journal of Clinical Microbiology
Open access |
15 Dec 2011 |
37 |
| 36 |
Use of a whole blood assay to evaluatein vitroT cell responses to new leprosy skin test antigens in leprosy patients and healthy subjects
Rosemary E. Weir, Patrick J. Brennan, Cynthia Ruth Butlin et al. · Clinical & Experimental Immunology
Open access |
May 1999 |
37 |
| 37 |
Identification of a systemic interferon-γ inducible antimicrobial gene signature in leprosy patients undergoing reversal reaction
Rosane M. B. Teles, Jing Nan Lu, Maria Tió‐Coma et al. · PLoS neglected tropical diseases
Open access |
10 Oct 2019 |
32 |
| 38 |
Opening a Can of Worms: Leprosy Reactions and Complicit Soil-Transmitted Helminths
Deanna A. Hagge, Pawan Parajuli, Chhatra B. Kunwar et al. · EBioMedicine
Open access |
Sep 2017 |
32 |
| 39 |
Development and evaluation of a novel multiple-primer PCR amplification refractory mutation system for the rapid detection of mutations conferring rifampicin resistance in codon 425 of the rpoB gene of Mycobacterium leprae
Bishwa R. Sapkota, Chaman Ranjit, Kapil Dev Neupane et al. · Journal of Medical Microbiology
|
17 Jan 2008 |
32 |
| 40 |
Tibialis posterior transfer for the correction of foot drop in leprosy. Long-term outcome.
Deydianne da Silva Soares · PubMed
|
1996 |
30 |
| 41 |
TIBIALIS POSTERIOR TRANSFER FOR THE CORRECTION OF FOOT DROP IN LEPROSY
Deydianne da Silva Soares · Journal of Bone and Joint Surgery - British Volume
|
1996 |
29 |
| 42 |
Human Beta-Defensin 3 Is Up-Regulated in Cutaneous Leprosy Type 1 Reactions
Anna L. Cogen, Stephen L. Walker, Chrissy h. Roberts et al. · PLoS neglected tropical diseases
Open access |
Nov 2012 |
29 |
| 43 |
Risk factors for type 1 reactions in leprosy.
PAUL W. ROCHE, J Le Master, Cynthia Ruth Butlin · PubMed
|
Dec 1997 |
28 |
| 44 |
Genetic Variation in Toll-Interacting Protein Is Associated With Leprosy Susceptibility and Cutaneous Expression of Interleukin 1 Receptor Antagonist
Javeed Ali Shah, William R. Berrington, Jay C. Vary et al. · The Journal of Infectious Diseases
Open access |
26 Nov 2015 |
28 |
| 45 |
Interventions for Stigma Reduction – Part 2: Practical Applications
Hugh Alistair Cross, Miriam L. Heijnders, Ajit K. Dalal et al. · Disability CBR & Inclusive Development
Open access |
15 Feb 2012 |
27 |
| 46 |
Mycobacterium leprae virulence-associated peptides are indicators of exposure to M. leprae in Brazil, Ethiopia and Nepal
Kidist Bobosha, Sheila Tuyet Tang, Jolien J. van der Ploeg-van Schip et al. · Memórias do Instituto Oswaldo Cruz
Open access |
Dec 2012 |
23 |
| 47 |
Rapid method for diagnosis of leprosy by measurements of antibodies to the M. leprae 35-kDa protein: comparison with PGL-I antibodies detected by ELISA and "dipstick" methods.
PAUL W. ROCHE, S S Failbus, Warwick J. Britton et al. · PubMed
|
Sep 1999 |
23 |
| 48 |
Methotrexate and prednisolone study in erythema nodosum leprosum (MaPs in ENL) protocol: a double-blind randomised clinical trial
Barbara de Barros, Saba M. Lambert, Mahesh Shah et al. · BMJ Open
Open access |
Nov 2020 |
21 |
| 49 |
Exploratory urinary metabolomics of type 1 leprosy reactions
Oleg A. Mayboroda, Anouk van Hooij, Rico J. E. Derks et al. · International Journal of Infectious Diseases
Open access |
27 Feb 2016 |
21 |
| 50 |
A method for rapid detection of rifampicin-resistant isolates ofMycobacterium leprae
Nadine Honoré, PAUL W. ROCHE, Jacques H.E. Grosset et al. · Leprosy Review
Open access |
2001 |
19 |