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Most cited papers from AOSpine

AOSpine

What are the most cited papers from AOSpine?

The most cited paper from AOSpine is "Inflammatory and catabolic signalling in intervertebral discs: The roles of NF-B and MAP Kinases" (Karin Wuertz‐Kozak, Nam N. Vo, Dimitris Kletsas et al., 2012), with 229 citations. Next come "Inflammatory Mediators in Intervertebral Disk Degeneration and Discogenic Pain" (219) and "Optimal surgical care for adolescent idiopathic scoliosis: an international consensus" (135).

Showing 50 of 61 papers. Every paper with more than 9 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Inflammatory and catabolic signalling in intervertebral discs: The roles of NF-B and MAP Kinases Karin Wuertz‐Kozak, Nam N. Vo, Dimitris Kletsas et al. · European Cells and Materials Open access 16 Feb 2012 229
2 Inflammatory Mediators in Intervertebral Disk Degeneration and Discogenic Pain Karin Wuertz‐Kozak, Lisbet Haglund · Global Spine Journal Open access 21 May 2013 219
3 Optimal surgical care for adolescent idiopathic scoliosis: an international consensus Marinus de Kleuver, Stephen J. Lewis, Niccole Germscheid et al. · European Spine Journal Open access 23 Jun 2014 135
4 Mobile spine chordoma: results of 166 patients from the AOSpine Knowledge Forum Tumor database Ziya L. Gokaslan et al. · Journal of Neurosurgery Spine Open access 18 Dec 2015 129
5 Surgical treatment of sacral chordoma: prognostic variables for local recurrence and overall survival Peter Pal Varga, Zsolt Szövérfi, Charles G. Fisher et al. · European Spine Journal 22 Dec 2014 116
6 Osteosarcoma of the spine: prognostic variables for local recurrence and overall survival, a multicenter ambispective study Mark B. Dekutoski, Michelle J. Clarke, Peter S. Rose et al. · Journal of Neurosurgery Spine Open access 4 Mar 2016 98
7 Expression and regulation of toll-like receptors (TLRs) in human intervertebral disc cells Marina Klawitter, Michiyuki Hakozaki, Hiroshi Kobayashi et al. · European Spine Journal Open access 4 Jul 2014 97
8 Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways Lilian Quero, Marina Klawitter, Anja Schmaus et al. · Arthritis Research & Therapy Open access 22 Aug 2013 94
9 The Red Wine Polyphenol Resveratrol Shows Promising Potential for the Treatment of Nucleus Pulposus–Mediated Pain In Vitro and In Vivo Karin Wuertz‐Kozak, Lilian Quero, Miho Sekiguchi et al. · Spine 17 May 2011 89
10 Age-related changes in human cervical, thoracal and lumbar intervertebral disc exhibit a strong intra-individual correlation Christoph Weiler, M. Schietzsch, T. Kirchner et al. · European Spine Journal Open access 11 Aug 2011 85
11 En Bloc Resection Versus Intralesional Surgery in the Treatment of Giant Cell Tumor of the Spine Raphaële Charest-Morin, Charles G. Fisher, Peter Pal Varga et al. · Spine 10 Feb 2017 78
12 The Impact of COVID-19 Pandemic on Spine Surgeons Worldwide Philip K. Louie, Garrett K. Harada, Michael H. McCarthy et al. · Global Spine Journal Open access 6 May 2020 75
13 Angiopoietin-1 receptor Tie2 distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells Adel Tekari, Samantha C. W. Chan, Daisuke Sakai et al. · Stem Cell Research & Therapy Open access 23 May 2016 68
14 Aneurysmal bone cysts of the spine: treatment options and considerations AOSpine Knowledge Forum Tumor, Stefano Boriani, Sheng-Fu Larry Lo et al. · Journal of Neuro-Oncology 24 Jul 2014 68
15 Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity Marina Klawitter, Lilian Quero, Juergen Klasen et al. · Journal of Inflammation Open access 21 Aug 2012 67
16 Systemic blood plasma CCL5 and CXCL6: Potential biomarkers for human lumbar disc degeneration Sibylle Grad, Cora Bow, Jaro Ilari Karppinen et al. · European Cells and Materials Open access 5 Jan 2016 66
17 Survival, local control, and health‐related quality of life in patients with oligometastatic and polymetastatic spinal tumors: A multicenter, international study Ori Barzilai, Anne L. Versteeg, Arjun Sahgal et al. · Cancer Open access 29 Nov 2018 65
18 Detrimental Role for Human High Temperature Requirement Serine Protease A1 (HTRA1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration André N. Tiaden, Marina Klawitter, Vanda Lux et al. · Journal of Biological Chemistry Open access 3 May 2012 64
19 Successful fishing for nucleus pulposus progenitor cells of the intervertebral disc across species Daisuke Sakai, Jordy Schol, Frances C. Bach et al. · JOR Spine Open access Jun 2018 63
20 Psychometric evaluation and adaptation of the Spine Oncology Study Group Outcomes Questionnaire to evaluate health‐related quality of life in patients with spinal metastases Anne L. Versteeg, Arjun Sahgal, Laurence D. Rhines et al. · Cancer Open access 6 Feb 2018 63
21 Current treatment strategy for newly diagnosed chordoma of the mobile spine and sacrum: results of an international survey Nicolas Dea et al. · Journal of Neurosurgery Spine Open access 16 Nov 2018 56
22 Predictors of Outcome in Patients with Cervical Spondylotic Myelopathy Undergoing Surgical Treatment: A Survey of Members from AOSpine International Lindsay A. Tetreault, Aria Nouri, Anoushka Singh et al. · World Neurosurgery 19 Sep 2013 55
23 Long-term outcomes in primary spinal osteochondroma: a multicenter study of 27 patients Daniel Michael Sciubba, Mohamed Macki, Mohamad Bydon et al. · Journal of Neurosurgery Spine Open access 20 Mar 2015 55
24 Activation of intervertebral disc cells by co-culture with notochordal cells, conditioned medium and hypoxia Benjamin Gantenbein, Elena Calandriello, Karin Wuertz‐Kozak et al. · BMC Musculoskeletal Disorders Open access Dec 2014 54
25 Triptolide exhibits anti-inflammatory, anti-catabolic as well as anabolic effects and suppresses TLR expression and MAPK activity in IL-1β treated human intervertebral disc cells Marina Klawitter, Lilian Quero, Juergen Klasen et al. · European Spine Journal Open access 25 Jul 2011 50
26 Responding to Intraoperative Neuromonitoring Changes During Pediatric Coronal Spinal Deformity Surgery Stephen J. Lewis, Ian H.Y. Wong, Samuel C. Strantzas et al. · Global Spine Journal Open access May 2019 45
27 An Assessment of the Key Predictors of Perioperative Complications in Patients with Cervical Spondylotic Myelopathy Undergoing Surgical Treatment: Results from a Survey of 916 AOSpine International Members Lindsay A. Tetreault, Aria Nouri, Anoushka Singh et al. · World Neurosurgery 11 Feb 2015 44
28 Spine surgeon perceptions of the challenges and benefits of telemedicine: an international study Grant J. Riew, Francis Campana Lovecchio, Dino Samartzis et al. · European Spine Journal Open access 16 Jan 2021 42
29 COVID-19 Impact Among Spine Surgeons in Latin America Alfredo J. Guiroy, Martin Julian Gagliardi, Nicolás Coombes et al. · Global Spine Journal Open access 12 May 2020 42
30 An international consensus on the appropriate evaluation and treatment for adults with spinal deformity AOSpine Knowledge Forum Deformity, Sigurd Berven, Steven James Kamper et al. · European Spine Journal Open access 5 Aug 2017 41
31 Spinal column chordoma: prognostic significance of clinical variables andT (brachyury) gene SNP rs2305089 for local recurrence and overall survival Chetan Bettegowda et al. · Neuro-Oncology Open access 23 Sep 2016 41
32 CD146 defines commitment of cultured annulus fibrosus cells to express a contractile phenotype Tomoko Nakai, Daisuke Sakai, Yoshihiko Nakamura et al. · Journal of Orthopaedic Research® Open access 8 Jun 2016 39
33 Ewing Sarcoma of the Spine Raphaële Charest-Morin, Michael S. Dirks, SHREYASKUMAR R. PATEL et al. · Spine 23 Aug 2017 38
34 Bupivacaine—the deadly friend of intervertebral disc cells? Lilian Quero, Marina Klawitter, Andreas G. Nerlich et al. · The Spine Journal 17 Dec 2010 38
35 Osteogenic differentiation of bone marrow stromal cells is hindered by the presence of intervertebral disc cells Samantha C. W. Chan, Adel Tekari, Lorin M. Benneker et al. · Arthritis Research & Therapy Open access 25 Dec 2015 36
36 Malignant peripheral nerve sheath tumors of the spine: results of surgical management from a multicenter study Dean Chou, Mark H. Bilsky, Alessandro Luzzati et al. · Journal of Neurosurgery Spine Open access 11 Nov 2016 34
37 Surgical management of spinal osteoblastomas Anne L. Versteeg, Nicolas Dea, Stefano Boriani et al. · Journal of Neurosurgery Spine Open access 7 Jul 2017 32
38 Provider confidence in the telemedicine spine evaluation: results from a global study Francis Campana Lovecchio, Grant J. Riew, Dino Samartzis et al. · European Spine Journal Open access 22 Nov 2020 31
39 A multicenter cohort study of spinal osteoid osteomas: results of surgical treatment and analysis of local recurrence Nasir A. Quraishi, Stefano Boriani, Silviu Sabou et al. · The Spine Journal 19 Oct 2016 31
40 COVID-19 and the rise of virtual medicine in spine surgery: a worldwide study Peter R. Swiatek, Joseph A. Weiner, Daniel J. Johnson et al. · European Spine Journal Open access 16 Jan 2021 30
41 Defining a core outcome set for adolescent and young adult patients with a spinal deformity Marinus de Kleuver, Sayf S. A. Faraj, Roderick M. Holewijn et al. · Acta Orthopaedica Open access 15 Sep 2017 30
42 Targeting earlier diagnosis: What symptoms come first in Degenerative Cervical Myelopathy? Colin Fraser Munro, Ratko Yurac, Zipser Carl Moritz et al. · PLoS ONE Open access 31 Mar 2023 27
43 Efetividade da metilprednisolona na fase aguda do trauma raquimedular: revisão sistemática dos ensaios clínicos randomizados Ricardo Vieira Botelho, Jefferson Walter Daniel, José Luis Romeo Boulosa et al. · Revista da Associação Médica Brasileira Open access 2009 27
44 Telemedicine in Spine Surgery: Global Perspectives and Practices Grant J. Riew, Francis Campana Lovecchio, Dino Samartzis et al. · Global Spine Journal Open access 14 Jun 2021 26
45 COVID ‐19: Current and future challenges in spine care and education ‐ a worldwide study Michael Thomas Nolte, Garrett K. Harada, Philip K. Louie et al. · JOR Spine Open access 28 Aug 2020 25
46 Prevailing Outcome Themes Reported by People With Degenerative Cervical Myelopathy: Focus Group Study Danyal Zaman Khan, Siobhan Mairead Fitzpatrick, Bryn Hilton et al. · JMIR Formative Research Open access 21 Sep 2020 24
47 The Challenges of Renal Cell Carcinoma Metastatic to the Spine: A Systematic Review of Survival and Treatment Courtney Rory Goodwin, Ali Karim Ahmed, Christine E. Boone et al. · Global Spine Journal ReviewOpen access 20 Nov 2017 21
48 Independent Reliability Analysis of a New Classification for Pyogenic Spondylodiscitis Gaston O Camino-Willhuber, Alfredo J. Guiroy, Juan Jose Zamorano et al. · Global Spine Journal Open access 13 Apr 2020 19
49 Prognostic significance of human telomerase reverse transcriptase promoter region mutations C228T and C250T for overall survival in spinal chordomas Chetan Bettegowda, Stephen S. F. Yip, Bowen Jiang et al. · Neuro-Oncology Open access 8 Apr 2019 19
50 AO Spine Adult Spinal Deformity Patient Profile: A Paradigm Shift in Comprehensive Patient Evaluation in Order to Optimize Treatment and Improve Patient Care J. Naresh‐Babu, Kenny Kwan, Yabin Wu et al. · Global Spine Journal Open access 17 Aug 2021 18

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.