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Most cited papers from AstraZeneca (United Kingdom)

What are the most cited papers from AstraZeneca (United Kingdom)?

The most cited paper from AstraZeneca (United Kingdom) is "Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines" (Clotilde Théry et al., 2018), with 11,535 citations. Next come "A roadmap for graphene" (9,276) and "A comparison of normalization methods for high density oligonucleotide array data based on variance and bias" (8,511).

Showing 50 of 59 papers. Every paper with more than 2,040 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Clotilde Théry et al. · Journal of Extracellular Vesicles Open access382 authors 23 Nov 2018 11,535
2 A roadmap for graphene Kostya S. Novoselov, Vladimir I. Fal’ko, Luigi Colombo et al. · Nature Oct 2012 9,276
3 A comparison of normalization methods for high density oligonucleotide array data based on variance and bias Benjamin M. Bolstad, Rafael A. Irizarry, Magnus Åstrand et al. · Bioinformatics Open access 21 Jan 2003 8,511
4 Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma Tony S.K. Mok, Yi-Long Lung Cancer Wu, Sumitra Thongprasert et al. · New England Journal of Medicine Open access 19 Aug 2009 8,331
5 Fluorine in medicinal chemistry Sophie Purser, Peter R. Moore, Steve Swallow et al. · Chemical Society Reviews Review 13 Dec 2007 7,580
6 Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes Lars C. Wallentin, Richard C. Becker, Andrzej Budaj et al. · New England Journal of Medicine Open access 30 Aug 2009 7,154
7 Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes Stephen D. Wiviott, Itamar Raz, Marc P. Bonaca et al. · New England Journal of Medicine Open access 10 Nov 2018 6,466
8 The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research Nathalie Percie du Sert et al. · PLoS Biology Open access 14 Jul 2020 6,005
9 Dapagliflozin in Patients with Chronic Kidney Disease Hiddo J.L. Heerspink, Bergur V. Stefánsson, Ricardo Correa‐Rotter et al. · New England Journal of Medicine Open access 24 Sep 2020 5,523
10 The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis Patrick M. Smith, Michael R. Howitt, Nicolai S. Panikov et al. · Science Open access 5 Jul 2013 5,478
11 Osimertinib in Untreated EGFR -Mutated Advanced Non–Small-Cell Lung Cancer Jean‐Charles Soria et al. · New England Journal of Medicine Open access 18 Nov 2017 5,475
12 Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK Merryn Voysey et al. · The Lancet Open access765 authors 8 Dec 2020 5,030
13 Drug repurposing: progress, challenges and recommendations Sudeep P. Pushpakom, Francesco Iorio, Patrick A. Eyers et al. · Nature Reviews Drug Discovery Review 12 Oct 2018 4,863
14 Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches Joshua A Welsh et al. · Journal of Extracellular Vesicles Open access Feb 2024 4,377
15 FinnGen provides genetic insights from a well-phenotyped isolated population Mitja Kurki et al. · Nature Open access169 authors 18 Jan 2023 4,362
16 Core outcome measures for chronic pain clinical trials: IMMPACT recommendations Robert H. Dworkin et al. · Pain 6 Nov 2004 3,789
17 Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers Peter C.C. Fong, David S. Boss, Timothy Anthony Yap et al. · New England Journal of Medicine Open access 24 Jun 2009 3,663
18 Core outcome domains for chronic pain clinical trials: IMMPACT recommendations Dennis C. Turk et al. · Pain 22 Sep 2003 3,518
19 Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus Benjamin M. Scirica, Deepak L. Bhatt, Eugene Braunwald et al. · New England Journal of Medicine Open access 2 Sep 2013 3,507
20 Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations Robert H. Dworkin et al. · Journal of Pain Open access 13 Dec 2007 3,496
21 Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity John O’Brien, Ian D. Wilson, Terry C. Orton et al. · European Journal of Biochemistry Open access Sep 2000 3,452
22 Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer Tony S.K. Mok, Yi-Long Lung Cancer Wu, Myung‐Ju Ahn et al. · New England Journal of Medicine Open access 6 Dec 2016 3,396
23 Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry Warwick B. Dunn, David Broadhurst, Paul Begley et al. · Nature Protocols 30 Jun 2011 3,360
24 Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation Mark E. Robson, Seock‐Ah Im, Elżbieta Senkus et al. · New England Journal of Medicine Open access 4 Jun 2017 3,322
25 Clinical Practice Guidelines for the Management Candidiasis: 2009 Update by the Infectious Diseases Society of America Peter G. Pappas, Carol A. Kauffman, David R. Andes et al. · Clinical Infectious Diseases Open access 29 Jan 2009 3,216
26 Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial Salim Yusuf, Marc Alan Pfeffer, Karl B Swedberg et al. · The Lancet Sep 2003 3,011
27 Overall Survival with Osimertinib in Untreated, EGFR -Mutated Advanced NSCLC Suresh S. Ramalingam et al. · New England Journal of Medicine Open access 21 Nov 2019 2,933
28 Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer Kathleen N. Moore et al. · New England Journal of Medicine Open access 21 Oct 2018 2,927
29 Pericytes regulate the blood–brain barrier Annika Armulik, Guillem Genové, Maarja Andaloussi Mäe et al. · Nature Open access 13 Oct 2010 2,915
30 Multi-Institutional Randomized Phase II Trial of Gefitinib for Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer Masahiro Fukuoka, Seiji Yano, Giuseppe Giaccone et al. · Journal of Clinical Oncology 20 May 2003 2,899
31 Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 Nathalie Percie du Sert et al. · PLoS Biology Open access 14 Jul 2020 2,875
32 Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction Scott David Solomon et al. · New England Journal of Medicine Open access 27 Aug 2022 2,863
33 A view on drug resistance in cancer Neil Vasan, José Baselga, David Michael Hyman · Nature Open access 13 Nov 2019 2,824
34 Premature ageing in mice expressing defective mitochondrial DNA polymerase Aleksandra Trifunović, Anna Wredenberg, Maria Falkenberg et al. · Nature May 2004 2,779
35 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors 2 Jan 2021 2,743
36 Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial John J.V. McMurray, Jan Östergren, Karl B Swedberg et al. · The Lancet Sep 2003 2,612
37 New insights into the genetic etiology of Alzheimer’s disease and related dementias Céline Bellenguez et al. · Nature Genetics Open access1,266 authors Apr 2022 2,608
38 Efficacy of Gefitinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in Symptomatic Patients With Non–Small Cell Lung Cancer Mark G. Kris, Ronald B. Natale, Roy S. Herbst et al. · JAMA 22 Oct 2003 2,547
39 The human tumor microbiome is composed of tumor type–specific intracellular bacteria Deborah Nejman et al. · Science Open access 28 May 2020 2,523
40 Diagnosis and Management of Childhood Obstructive Sleep Apnea Syndrome Carole L. Marcus, Lee J. Brooks, Kari A. Draper et al. · PEDIATRICS 27 Aug 2012 2,431
41 Quantifying the chemical beauty of drugs G. Richard Bickerton, Gaia Valeria Paolini, Jérémy Besnard et al. · Nature Chemistry Open access 24 Jan 2012 2,382
42 The influence of drug-like concepts on decision-making in medicinal chemistry Paul D. Leeson, Brian Springthorpe · Nature Reviews Drug Discovery Review 31 Oct 2007 2,354
43 Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist Sama I. Sayin, Annika M. Wahlstrom, Jenny Felin et al. · Cell Metabolism Open access Feb 2013 2,351
44 Olaparib for Metastatic Castration-Resistant Prostate Cancer Johann Sebastian De Bono, Joaquı́n Mateo, Karim S. Fizazi et al. · New England Journal of Medicine Open access 28 Apr 2020 2,322
45 Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial Luis G Paz-Ares et al. · The Lancet 246 authors 4 Oct 2019 2,310
46 Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial M. William Audeh, James Carmichael, Richard T. Penson et al. · The Lancet Jul 2010 2,298
47 AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer Darren A.E. Cross et al. · Cancer Discovery Open access 4 Jun 2014 2,276
48 Molecular Analysis of Commensal Host-Microbial Relationships in the Intestine Lora V. Hooper, Melissa Hirose Wong, Anders G Thelin et al. · Science 2 Feb 2001 2,232
49 Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes Rury R. Holman, Mary Angelyn Bethel, Robert John Mentz et al. · New England Journal of Medicine Open access 14 Sep 2017 2,195
50 What is meant by intention to treat analysis? Survey of published randomised controlled trials S. Hollis, Fiona Campbell · BMJ Open access 11 Sep 1999 2,188

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.