| 1 |
Lack of Fucose on Human IgG1 N-Linked Oligosaccharide Improves Binding to Human FcγRIII and Antibody-dependent Cellular Toxicity
Robert L. Shields, Jadine Lai, Rodney G. Keck et al. · Journal of Biological Chemistry
Open access |
Jul 2002 |
1,849 |
| 2 |
The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication
Přemysl Berčík, A. J. Park, D. Sinclair et al. · Neurogastroenterology & Motility
Open access |
11 Oct 2011 |
1,030 |
| 3 |
Large-Scale Human Metabolomics Studies: A Strategy for Data (Pre-) Processing and Validation
Sabina Bijlsma, I. Bobeldijk, Elwin R. Verheij et al. · Analytical Chemistry
|
14 Dec 2005 |
886 |
| 4 |
Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue
Michael J. Gerdes et al. · Proceedings of the National Academy of Sciences
Open access |
Jul 2013 |
802 |
| 5 |
Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography–tandem mass spectrometry
Cara Polson, Pratibha Sarkar, Bev Incledon et al. · Journal of Chromatography B
|
30 Jan 2003 |
697 |
| 6 |
Oxidative stress and inflammation in the pathogenesis of neurological disorders: Mechanisms and implications
Umesh Chandra Dash, Nitish Kumar Bhol, Sandeep Kumar Swain et al. · Acta Pharmaceutica Sinica B
Open access |
16 Oct 2024 |
676 |
| 7 |
Chemical derivatization and mass spectral libraries in metabolic profiling by GC/MS and LC/MS/MS
John M. Halket, Daniel Waterman, Anna M. Przyborowska et al. · Journal of Experimental Botany
Open access |
20 Dec 2004 |
664 |
| 8 |
Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean
John C. Clapham et al. · Nature
|
Jul 2000 |
616 |
| 9 |
A phase III randomized trial of gantenerumab in prodromal Alzheimer’s disease
for the SCarlet RoAD Investigators, Susanne Ostrowitzki, Robert A. Lasser et al. · Alzheimer s Research & Therapy
Open access |
Dec 2017 |
576 |
| 10 |
Fecal Calprotectin Correlates More Closely With the Simple Endoscopic Score for Crohn's Disease (SES-CD) than CRP, Blood Leukocytes, and the CDAI
Alain M. Schoepfer, Christoph Beglinger, Alex Straumann et al. · The American Journal of Gastroenterology
Open access |
15 Sep 2009 |
574 |
| 11 |
Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism
Sylvie Rabot, Mathieu Membrez, Aurélia Bruneau et al. · The FASEB Journal
|
20 Aug 2010 |
563 |
| 12 |
Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants
Birgit Holst, Gary Williamson · Current Opinion in Biotechnology
Review |
Apr 2008 |
534 |
| 13 |
Preclinical Pharmacokinetics of Ranibizumab (rhuFabV2) after a Single Intravitreal Administration
Jacques Gaudreault, David Fei, Jeriza Rusit et al. · Investigative Ophthalmology & Visual Science
|
26 Jan 2005 |
504 |
| 14 |
Mapping of the C1q Binding Site on Rituxan, a Chimeric Antibody with a Human IgG1 Fc
Esohe E Idusogie, Leonard G. Presta, Hélène Gazzano-Santoro et al. · The Journal of Immunology
Open access |
Apr 2000 |
430 |
| 15 |
Electrochemical characterization of carbohydrate oxidation at copper electrodes
Juan Miguel Marioli, Theodore Kuwana · Electrochimica Acta
|
Jun 1992 |
352 |
| 16 |
Comparisons of the Intraocular Tissue Distribution, Pharmacokinetics, and Safety of 125I-Labeled Full-Length and Fab Antibodies in Rhesus Monkeys Following Intravitreal Administration
Joyce J. Mordenti, R. Andrew Cuthbertson, Napoleone Ferrara et al. · Toxicologic Pathology
|
Sep 1999 |
351 |
| 17 |
Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes
Sandrine P. Claus, Tsz Mon Tsang, Yulan L. Wang et al. · Molecular Systems Biology
Open access |
14 Oct 2008 |
342 |
| 18 |
The metagenome of a biogas-producing microbial community of a production-scale biogas plant fermenter analysed by the 454-pyrosequencing technology
Andreas Schlüter, Thomas Bekel, Naryttza N. Diaz et al. · Journal of Biotechnology
|
29 May 2008 |
332 |
| 19 |
Ulcerative colitis
Alain M. Schoepfer, Christoph Beglinger, Alex Straumann et al. · Inflammatory Bowel Diseases
|
21 May 2009 |
331 |
| 20 |
Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein
Cindy L. Will, Henning Urlaub, Tilmann Achsel et al. · The EMBO Journal
Open access |
16 Sep 2002 |
310 |
| 21 |
Fecal Calprotectin More Accurately Reflects Endoscopic Activity of Ulcerative Colitis than the Lichtiger Index, C-reactive Protein, Platelets, Hemoglobin, and Blood Leukocytes
Alain M. Schoepfer, Christoph Beglinger, Alex Straumann et al. · Inflammatory Bowel Diseases
Open access |
17 Jan 2013 |
299 |
| 22 |
A highly selective solid phase extraction sorbent for pre-concentration of sameridine made by molecular imprinting
Lars I. Andersson, P. Alison Paprica, Torbjörn Arvidsson · Chromatographia
|
Jul 1997 |
294 |
| 23 |
Engineered Antibodies with Increased Activity to Recruit Complement
Esohe E Idusogie, Pin Yee Wong, Leonard G. Presta et al. · The Journal of Immunology
Open access |
Feb 2001 |
293 |
| 24 |
OMICS-driven biomarker discovery in nutrition and health
Martin Kussmann, Frédéric Raymond, Michael Affolter · Journal of Biotechnology
|
5 Apr 2006 |
286 |
| 25 |
Amodiaquine Clearance and Its Metabolism to N-Desethylamodiaquine Is Mediated by CYP2C8: A New High Affinity and Turnover Enzyme-Specific Probe Substrate
Xueqing Li, Anders Björkman, Tommy B. Andersson et al. · Journal of Pharmacology and Experimental Therapeutics
|
Feb 2002 |
286 |
| 26 |
A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-β Production in Vivo
Jasvinder K. Atwal, Yongmei Chen, Cecilia Chiu et al. · Science Translational Medicine
|
25 May 2011 |
277 |
| 27 |
Nutritional Metabonomics: Applications and Perspectives
Serge Rezzi, Ziad Ramadan, Laurent Bernard Fay et al. · Journal of Proteome Research
|
11 Jan 2007 |
270 |
| 28 |
A target‐mediated model to describe the pharmacokinetics and hemodynamic effects of recombinant human vascular endothelial growth factor in humans
Stephen M. Eppler, Daniel L. Combs, Timothy D. Henry et al. · Clinical Pharmacology & Therapeutics
|
Jul 2002 |
269 |
| 29 |
Phylogenetic characterization of a biogas plant microbial community integrating clone library 16S-rDNA sequences and metagenome sequence data obtained by 454-pyrosequencing
Magdalena Kröber, Thomas Bekel, Naryttza N. Diaz et al. · Journal of Biotechnology
|
28 Feb 2009 |
264 |
| 30 |
AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer
Michael J. Giffin et al. · Clinical Cancer Research
Open access |
17 Nov 2020 |
262 |
| 31 |
Whey Protein Soluble Aggregates from Heating with NaCl: Physicochemical, Interfacial, and Foaming Properties
Christophe Schmitt, Claudine Bovay, Martine Rouvet et al. · Langmuir
|
7 Mar 2007 |
252 |
| 32 |
Host‐related factors explaining interindividual variability of carotenoid bioavailability and tissue concentrations in humans
Torsten Bohn, Charles Desmarchelier, Lars Ove Dragsted et al. · Molecular Nutrition & Food Research
Open access |
19 Jan 2017 |
251 |
| 33 |
Joint EFLM-COLABIOCLI Recommendation for venous blood sampling
Ana-Maria Šimundić et al. · Clinical Chemistry and Laboratory Medicine (CCLM)
Open access |
14 Jul 2018 |
243 |
| 34 |
Integrated Bimodal Waveguide Interferometric Biosensor for Label-Free Analysis
Kirill E. Zinoviev, Ana Belén González‐Guerrero, Carlos Domı́nguez et al. · Journal of Lightwave Technology
Open access |
10 May 2011 |
240 |
| 35 |
A central role for amyloid fibrin microclots in long COVID/PASC: Origins and therapeutic implications
Douglas Bruce Kell, Gert Jacobus Laubscher, Etheresia Pretorius · Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)
Open access |
2022 |
239 |
| 36 |
Engineering Human IgG1 Affinity to Human Neonatal Fc Receptor: Impact of Affinity Improvement on Pharmacokinetics in Primates
Yik Andy Yeung, Maya Kaushal Leabman, Jonathan S. Marvin et al. · The Journal of Immunology
Open access |
Jun 2009 |
238 |
| 37 |
Taxonomic composition and gene content of a methane-producing microbial community isolated from a biogas reactor
Lutz Krause, Naryttza N. Diaz, Robert Alan Edwards et al. · Journal of Biotechnology
|
21 Jun 2008 |
236 |
| 38 |
Dysregulation of lipids in Alzheimer's disease and their role as potential biomarkers
Matthew Wai Kin Wong, Nady Braidy, Anne Poljak et al. · Alzheimer s & Dementia
Open access |
24 Feb 2017 |
235 |
| 39 |
Simultaneous determination of 12 steroids by isotope dilution liquid chromatography-photospray ionization tandem mass spectrometry
Tiedong Guo, Robert L. Taylor, Ravinder Singh et al. · Clinica Chimica Acta
|
5 Apr 2006 |
226 |
| 40 |
Probing gender-specific metabolism differences in humans by nuclear magnetic resonance-based metabonomics
Sunil Kochhar, Doris M. Jacobs, Ziad Ramadan et al. · Analytical Biochemistry
|
21 Mar 2006 |
224 |
| 41 |
Potential Mechanisms for Thrombocytopenia Development with Trastuzumab Emtansine (T-DM1)
Hirdesh Uppal, Estelle Doudement, Kaushiki Mahapatra et al. · Clinical Cancer Research
|
4 Nov 2014 |
215 |
| 42 |
Integrated chip‐based capillary electrophoresis
Carlo S. Effenhauser, Gerard J. M. Bruin, Aran Paulus · Electrophoresis
|
1997 |
213 |
| 43 |
Safety, Pharmacokinetics, and Pharmacodynamics of Single Doses of LXR‐623, a Novel Liver X‐Receptor Agonist, in Healthy Participants
Arie Katz, Chandrasekhar Udata, Elyssa Ott et al. · The Journal of Clinical Pharmacology
|
28 Apr 2009 |
213 |
| 44 |
Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics
Angela Schoch, Hubert Kettenberger, Olaf Mundigl et al. · Proceedings of the National Academy of Sciences
Open access |
27 Apr 2015 |
209 |
| 45 |
Quantitative Comparison of Glutamatergic and GABAergic Synaptic Vesicles Unveils Selectivity for Few Proteins Including MAL2, a Novel Synaptic Vesicle Protein
Mads Grønborg, Nathan John Pavlos, Irene Brunk et al. · Journal of Neuroscience
Open access |
6 Jan 2010 |
198 |
| 46 |
TACOA – Taxonomic classification of environmental genomic fragments using a kernelized nearest neighbor approach
Naryttza N. Diaz, Lutz Krause, Alexander Goesmann et al. · BMC Bioinformatics
Open access |
11 Feb 2009 |
196 |
| 47 |
Design and Conduct Considerations for First‐in‐Human Trials
Jie Shen, Brandon Swift, Richard D. Mamelok et al. · Clinical and Translational Science
Open access |
26 Jul 2018 |
188 |
| 48 |
Continuous in Vivo Monitoring of Amino Acid Neurotransmitters by Microdialysis Sampling with Online Derivatization and Capillary Electrophoresis Separation
Simon Yuji. Zhou, Hong Xiang Zuo, John F. Stobaugh et al. · Analytical Chemistry
|
Feb 1995 |
185 |
| 49 |
Conservation of the Protein Composition and Electron Microscopy Structure of Drosophila melanogaster and Human Spliceosomal Complexes
Nadine Herold, Cindy L. Will, Elmar Wolf et al. · Molecular and Cellular Biology
Open access |
3 Nov 2008 |
177 |
| 50 |
Online Coupling of in vivo Microdialysis Sampling with Capillary Electrophoresis
Barry L. Hogan, Susan M. Lunte, John F. Stobaugh et al. · Analytical Chemistry
|
Mar 1994 |
170 |