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Institution · BioCryst Pharmaceuticals (United States)

Most cited papers from BioCryst Pharmaceuticals (United States)

BioCryst Pharmaceuticals (United States)

What are the most cited papers from BioCryst Pharmaceuticals (United States)?

The most cited paper from BioCryst Pharmaceuticals (United States) is "Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430" (Travis K. Warren, Jay B. Wells, Rekha G. Panchal et al., 2014), with 617 citations. Next come "BCX-1812 (RWJ-270201): Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design" (381) and "Donor heart and lung procurement: A consensus statement" (201).

Showing 50 of 60 papers. Every paper with more than 41 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430 Travis K. Warren, Jay B. Wells, Rekha G. Panchal et al. · Nature Open access 2 Mar 2014 617
2 BCX-1812 (RWJ-270201): Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design Yarlagadda S. Babu, Pooran Chand, Shanta Bantia et al. · Journal of Medicinal Chemistry Open access 31 Aug 2000 381
3 Donor heart and lung procurement: A consensus statement Hannah Copeland et al. · The Journal of Heart and Lung Transplantation Open access 21 Apr 2020 201
4 BCX4430 – A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease Raymond Taylor, Pravin L. Kotian, Travis K. Warren et al. · Journal of Infection and Public Health Open access 18 Apr 2016 179
5 Systematic Structure-Based Design and Stereoselective Synthesis of Novel Multisubstituted Cyclopentane Derivatives with Potent Antiinfluenza Activity Pooran Chand, Pravin L. Kotian, Ali C. Dehghani et al. · Journal of Medicinal Chemistry Open access 31 Oct 2001 176
6 Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial Bruce L. Zuraw et al. · Journal of Allergy and Clinical Immunology Open access 21 Oct 2020 174
7 Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse model Justin G. Julander, Venkatraman Siddharthan, Joe T. Evans et al. · Antiviral Research Open access 10 Nov 2016 166
8 Topical nanocrystalline silver cream suppresses inflammatory cytokines and induces apoptosis of inflammatory cells in a murine model of allergic contact dermatitis Kailash C. Bhol, Paul J. Schechter · British Journal of Dermatology Jun 2005 157
9 Anti-influenza virus activity of peramivir in mice with single intramuscular injection Shanta Bantia, Carrie Arnold, Cynthia Davis Parker et al. · Antiviral Research 22 Nov 2005 149
10 Comparison of the Anti-Influenza Virus Activity of RWJ-270201 with Those of Oseltamivir and Zanamivir Shanta Bantia, Cynthia Davis Parker, Sandya L. Ananth et al. · Antimicrobial Agents and Chemotherapy Open access Apr 2001 148
11 Three-dimensional Structure of Influenza A N9 Neuraminidase and Its Complex with the Inhibitor 2-Deoxy 2,3-Dehydro-N-Acetyl Neuraminic Acid P. Bossart-Whitaker, Mike Carson, Yarlagadda S. Babu et al. · Journal of Molecular Biology Aug 1993 142
12 Effects of Nanocrystalline Silver (NPI 32101) in a Rat Model of Ulcerative Colitis Kailash C. Bhol, Paul J. Schechter · Digestive Diseases and Sciences 12 Apr 2007 136
13 Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(Arylmethyl) derivatives of 9-deazaguanine John A. Jr. Montgomery, Shri Niwas, Jerry D. Rose et al. · Journal of Medicinal Chemistry Open access 1993 133
14 Evaluation of Intravenous Peramivir for Treatment of Influenza in Hospitalized Patients Menno D. de Jong, Michael G. Ison, Arnold S. Monto et al. · Clinical Infectious Diseases 12 Aug 2014 123
15 Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema Emel Aygören‐Pürsün et al. · New England Journal of Medicine Open access 25 Jul 2018 114
16 Sofosbuvir (GS-7977) plus peginterferon/ribavirin in treatment-naïve patients with HCV genotype 1: A randomized, 28-day, dose-ranging trial Maribel Rodriguez‐Torres, Eric Lawitz, Kris V. Kowdley et al. · Journal of Hepatology 23 Nov 2012 107
17 A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine) Varsha V. Gandhi, John Michael Kilpatrick, William K. Plunkett et al. · Blood Open access Sep 2005 101
18 BCX4430, a Novel Nucleoside Analog, Effectively Treats Yellow Fever in a Hamster Model Justin G. Julander, Shanta Bantia, Brian R. Taubenheim et al. · Antimicrobial Agents and Chemotherapy Open access 26 Aug 2014 99
19 In Vivo Influenza Virus-Inhibitory Effects of the Cyclopentane Neuraminidase Inhibitor RWJ-270201 Robert W. Sidwell, Donald F. Smee, John H. Huffman et al. · Antimicrobial Agents and Chemotherapy Open access Mar 2001 97
20 Anti-inflammatory effect of topical nanocrystalline silver cream on allergic contact dermatitis in a guinea pig model Kailash C. Bhol, Joseph Alroy, Paul J. Schechter · Clinical and Experimental Dermatology 29 Apr 2004 97
21 Clinical Experience in Adults and Children Treated with Intravenous Peramivir for 2009 Influenza A (H1N1) Under an Emergency IND Program in the United States Jaime E. Hernández, Raghavendra Adiga, Robert W. Armstrong et al. · Clinical Infectious Diseases Open access 23 Feb 2011 93
22 The crystal structure of the aldose reductase.NADPH binary complex. David W. Borhani, Theresa M. Harter, Jonathan Mark Petrash · Journal of Biological Chemistry Open access Dec 1992 92
23 Addition of Lithiated 9-Deazapurine Derivatives to a Carbohydrate Cyclic Imine: Convergent Synthesis of the Aza-C-nucleoside Immucillins Gary B. Evans, Richard H. Furneaux, Tracy L. Hutchison et al. · The Journal of Organic Chemistry Aug 2001 91
24 Design and Synthesis of Benzoic Acid Derivatives as Influenza Neuraminidase Inhibitors Using Structure-Based Drug Design Pooran Chand, Yarlagadda S. Babu, Shanta Bantia et al. · Journal of Medicinal Chemistry Open access Dec 1997 90
25 Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)—a novel potent and orally active immunosuppressive agent Shanta Bantia, Patrick J. Miller, Cynthia Davis Parker et al. · International Immunopharmacology Jun 2001 89
26 Efficacy of Novel Hemagglutinin-Neuraminidase Inhibitors BCX 2798 and BCX 2855 against Human Parainfluenza Viruses In Vitro and In Vivo Irina V. Alymova, Garry L. Taylor, Toru Takimoto et al. · Antimicrobial Agents and Chemotherapy Open access 22 Apr 2004 87
27 Isolation and characterization of an anti-complementary polysaccharide D3-S1 from the roots of Bupleurum smithii Xu Han, Yunyi Zhang, Jianwen Zhang et al. · International Immunopharmacology 6 Oct 2006 87
28 An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral Justin G. Julander, James F. Demarest, Ray Taylor et al. · Antiviral Research Open access 20 Sep 2021 84
29 Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor—BCX-1777 Shanta Bantia, Sandya L. Ananth, Cynthia Davis Parker et al. · International Immunopharmacology 7 Apr 2003 78
30 A Clinical Trial of Intravenous Peramivir Compared with Oral Oseltamivir for the Treatment of Seasonal Influenza in Hospitalized Adults Michael G. Ison, David S.C. Hui, Kate R. Clezy et al. · Antiviral Therapy 30 Oct 2012 76
31 Galidesivir limits Rift Valley fever virus infection and disease in Syrian golden hamsters Jonna B. Westover, Amanda Mathis, Ray Taylor et al. · Antiviral Research Open access Jun 2018 75
32 Crystal structures of nucleoside 2-deoxyribosyltransferase in native and ligand-bound forms reveal architecture of the active site ShellyR Armstrong, William J. Cook, Steven A. Short et al. · Structure Open access 1996 73
33 Purine nucleoside phosphorylase: A target for drug design John A. Jr. Montgomery · Medicinal Research Reviews May 1993 72
34 Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/Vietnam/1203/04 (H5N1) Nadezhda E. Yun, Nathaniel Seth Linde, Michele A. Zacks et al. · Virology Open access 30 Jan 2008 70
35 Plasmodium falciparum Parasites Are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model María B. Cassera, Keith Z. Hazleton, Emilio F. Merino et al. · PLoS ONE Open access 11 Nov 2011 70
36 Facile Electrochemical Characterization of Core/Shell Nanoparticles. Ag Core/Ag2O Shell Structures Jalal Ghilane, FU‐REN FRANK FAN, Allen J. Bard et al. · Nano Letters 3 Apr 2007 68
37 Comparison of the anti-influenza virus activity of cyclopentane derivatives with oseltamivir and zanamivir in vivo Pooran Chand, Shanta Bantia, Pravin L. Kotian et al. · Bioorganic & Medicinal Chemistry 26 Apr 2005 66
38 Structures of native and complexed complement factor D: implications of the atypical his57 conformation and self-inhibitory loop in the regulation of specific serine protease activity Jing Hua, Y. Sudhakara Babu, Dwight Moore et al. · Journal of Molecular Biology Oct 1998 65
39 Randomized Trial of the Efficacy and Safety of Berotralstat (BCX7353) as an Oral Prophylactic Therapy for Hereditary Angioedema: Results of APeX-2 Through 48 Weeks (Part 2) H. James Wedner, Emel Aygören‐Pürsün, Jonathan A. Bernstein et al. · The Journal of Allergy and Clinical Immunology In Practice Open access 16 Apr 2021 64
40 Structure-based design of inhibitors of purine nucleoside phosphorylase. 3. 9-Arylmethyl derivatives of 9-deazaguanine substituted on the arylmethyl group Mark D. Erion, Shri Niwas, Jerry D. Rose et al. · Journal of Medicinal Chemistry Open access Nov 1993 64
41 Combinations of favipiravir and peramivir for the treatment of pandemic influenza A/California/04/2009 (H1N1) virus infections in mice E. Bart Tarbet, Masako Maekawa, Yousuke Furuta et al. · Antiviral Research Open access 10 Mar 2012 62
42 Spatial survey of a magnetron plasma sputtering system using a Langmuir probe David J Field, S. K. Dew, Robert Edward Burrell · Journal of Vacuum Science & Technology A Vacuum Surfaces and Films Nov 2002 61
43 Potent Inhibition of Influenza Sialidase by a Benzoic Acid Containing a 2-Pyrrolidinone Substituent Venkatram R. Atigadda, Wayne J. Brouillette, Franco J. Duarte et al. · Journal of Medicinal Chemistry Open access 4 Jun 1999 59
44 Long‐term safety and effectiveness of berotralstat for hereditary angioedema: The open‐label APeX‐S study Henriette Farkas et al. · Clinical and Translational Allergy Open access Jun 2021 58
45 In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia Irene Homminga, Christian Michel Zwaan, Chantal Y. Manz et al. · Blood Open access 6 Jul 2011 57
46 The Arthus Reaction in Rodents: Species-Specific Requirement of Complement Alexander J. Szalai, Stanley B. Digerness, Alok Chandra Agrawal et al. · The Journal of Immunology 2000 57
47 Combinations of oseltamivir and peramivir for the treatment of influenza A (H1N1) virus infections in cell culture and in mice Donald F. Smee, Brett L. Hurst, Min‐Hui Wong et al. · Antiviral Research Open access 14 Jul 2010 56
48 Syntheses and Neuraminidase Inhibitory Activity of Multisubstituted Cyclopentane Amide Derivatives Pooran Chand, Yarlagadda S. Babu, Shanta Bantia et al. · Journal of Medicinal Chemistry Open access 13 Mar 2004 56
49 Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM Roberto Alonso, Mònica López‐Guerra, Ramanda Upshaw et al. · Blood 19 Jun 2009 54
50 Generation and Characterization of a Mutant of Influenza A Virus Selected with the Neuraminidase Inhibitor BCX-140 Shanta Bantia, Anita A. Ghate, Sandya L. Ananth et al. · Antimicrobial Agents and Chemotherapy Open access Apr 1998 50

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.