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Most cited papers from Bioinformatics Solutions (Canada)

What are the most cited papers from Bioinformatics Solutions (Canada)?

The most cited paper from Bioinformatics Solutions (Canada) is "Initial sequencing and comparative analysis of the mouse genome" (Asif T. Chinwalla et al., 2002), with 7,343 citations. Next come "PEAKS: powerful software for peptide de novo sequencing by tandem mass spectrometry" (1,409) and "PEAKS DB: De Novo Sequencing Assisted Database Search for Sensitive and Accurate Peptide Identification" (1,132).

Showing 50 of 59 papers. Every paper with more than 8 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Initial sequencing and comparative analysis of the mouse genome Asif T. Chinwalla et al. · Nature Open access223 authors Dec 2002 7,343
2 PEAKS: powerful software for peptide de novo sequencing by tandem mass spectrometry Bin Ma, Kaizhong Zhang, Christopher Hendrie et al. · Rapid Communications in Mass Spectrometry 19 Sep 2003 1,409
3 PEAKS DB: De Novo Sequencing Assisted Database Search for Sensitive and Accurate Peptide Identification Jing Zhang, Lei Xin, Baozhen Shan et al. · Molecular & Cellular Proteomics Open access 21 Dec 2011 1,132
4 PatternHunter: faster and more sensitive homology search Bin Ma, John Tromp, Ming Li · Bioinformatics Mar 2002 865
5 An information-based sequence distance and its application to whole mitochondrial genome phylogeny Ming Li, Jonathan H. Badger, Xin Chen et al. · Bioinformatics Open access Feb 2001 543
6 De novo peptide sequencing by deep learning Ngoc Hieu Tran, Xianglilan Zhang, Lei Xin et al. · Proceedings of the National Academy of Sciences Open access 18 Jul 2017 485
7 Deep learning enables de novo peptide sequencing from data-independent-acquisition mass spectrometry Ngoc Hieu Tran, Rui Qiao, Lei Xin et al. · Nature Methods 7 Dec 2018 395
8 PATTERNHUNTER II: HIGHLY SENSITIVE AND FAST HOMOLOGY SEARCH MING LI, BIN MA, Derek Kisman et al. · Journal of Bioinformatics and Computational Biology Sep 2004 231
9 DNACompress: fast and effective DNA sequence compression Xin Chen, Ming Li, Bin Ma et al. · Bioinformatics Open access Dec 2002 211
10 PeaksPTM: Mass Spectrometry-Based Identification of Peptides with Unspecified Modifications Han Xi, Lin He, Lei Xin et al. · Journal of Proteome Research 24 May 2011 183
11 Complete De Novo Assembly of Monoclonal Antibody Sequences Ngoc Hieu Tran, M. Ziaur Rahman, Lin He et al. · Scientific Reports Open access 26 Aug 2016 173
12 A streamlined platform for analyzing tera-scale DDA and DIA mass spectrometry data enables highly sensitive immunopeptidomics Lei Xin, Rui Qiao, Xin Chen et al. · Nature Communications Open access 7 Jun 2022 109
13 Mondo: Unifying diseases for the world, by the world Nicole Vasilevsky et al. · medRxiv PreprintOpen access 16 Apr 2022 104
14 Computationally instrument-resolution-independent de novo peptide sequencing for high-resolution devices Rui Qiao, Ngoc Hieu Tran, Lei Xin et al. · Nature Machine Intelligence 18 Mar 2021 103
15 Expanding Proteome Coverage with CHarge Ordered Parallel Ion aNalysis (CHOPIN) Combined with Broad Specificity Proteolysis Simon A. Davis, Philip D. Charles, Lin He et al. · Journal of Proteome Research Open access 6 Feb 2017 100
16 The similarity metric Ming Li, Xin Chen, Xin Yan Li et al. · UvA-DARE (University of Amsterdam) Conference paper 12 Jan 2003 98
17 Chemoproteomic profiling and discovery of protein electrophiles in human cells Megan L. Matthews, Lin He, Benjamin D. Horning et al. · Nature Chemistry Open access 31 Oct 2016 93
18 A draft genome sequence of the elusive giant squid, Architeuthis dux Rute R. da Fonseca et al. · GigaScience Open access 2020 92
19 Climate change, non‐indigenous species and shipping: assessing the risk of species introduction to a high‐ A rctic archipelago Chris Ware, Jørgen Berge, Jan Henry Sundet et al. · Diversity and Distributions Open access 12 Aug 2013 89
20 GlycoMaster DB: Software To Assist the Automated Identification of N-Linked Glycopeptides by Tandem Mass Spectrometry He Lin, Lei Xin, Baozhen Shan et al. · Journal of Proteome Research 12 Aug 2014 87
21 DeepIso: A Deep Learning Model for Peptide Feature Detection from LC-MS map Fatema Tuz Zohora, M. Ziaur Rahman, Ngoc Hieu Tran et al. · Scientific Reports Open access 20 Nov 2019 85
22 A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism J.J.David Ho, Nathan C. Balukoff, Phaedra R. Theodoridis et al. · Nature Communications Open access 29 May 2020 67
23 Glycopeptide database search and de novo sequencing with PEAKS GlycanFinder enable highly sensitive glycoproteomics Weiping Sun, Qianqiu Zhang, Xiyue Zhang et al. · Nature Communications Open access 8 Jul 2023 60
24 Better score function for peptide identification with ETD MS/MS spectra Xiaowen Liu, Baozhen Shan, Lei Xin et al. · BMC Bioinformatics Open access 2010 48
25 A randomized phase 2b trial examined the effects of the glucagon-like peptide-1 and glucagon receptor agonist cotadutide on kidney outcomes in patients with diabetic kidney disease Viknesh Selvarajah et al. · Kidney International Open access 30 Aug 2024 43
26 Grand challenges in bioinformatics education and training Esra Büşra Işık et al. · Nature Biotechnology Aug 2023 43
27 An effective algorithm for peptide de novo sequencing from MS/MS spectra Bin Ma, Kaizhong Zhang, Chengzhi Liang · Journal of Computer and System Sciences Open access 8 Feb 2005 43
28 Personalized deep learning of individual immunopeptidomes to identify neoantigens for cancer vaccines Ngoc Hieu Tran, Rui Qiao, Lei Xin et al. · Nature Machine Intelligence 16 Nov 2020 42
29 Digestion-Free Analysis of Peptides from 30-year-old Formalin-Fixed, Paraffin-Embedded Tissue by Mass Spectrometry Imaging Martin R. L. Paine, Shane R. Ellis, Dan Maloney et al. · Analytical Chemistry Open access 5 Jul 2018 42
30 Automated protein (re)sequencing with MS/MS and a homologous database yields almost full coverage and accuracy Xiaowen Liu, Yonghua Han, Denis Yuen et al. · Bioinformatics 17 Jun 2009 40
31 Mitigating the missing-fragmentation problem in de novo peptide sequencing with a two-stage graph-based deep learning model Zeping Mao, Ruixue Zhang, Lei Xin et al. · Nature Machine Intelligence 19 Oct 2023 38
32 Forewing pigmentation predicts migration distance in wild-caught migratory monarch butterflies Daniel Hanley, Nathan G. Miller, D. T. Tyler Flockhart et al. · Behavioral Ecology 2013 34
33 The WRKY Transcription Factor Genes in Eggplant (Solanum melongena L.) and Turkey Berry (Solanum torvum Sw.) Xu Yang, Cao Deng, Yu Zhang et al. · International Journal of Molecular Sciences Open access 7 Apr 2015 32
34 Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome J.J.David Ho, Tyler Andrew Cunningham, Paola Manara et al. · Cell Reports Open access Oct 2021 30
35 tPatternHunter: gapped, fast and sensitive translated homology search Derek Kisman, Ming Li, Bin Ma et al. · Bioinformatics Open access 16 Sep 2004 28
36 Covalent Immune Proximity-Induction Strategy Using SuFEx-Engineered Bifunctional Viral Peptides Harrison M. McCann, Benjamin P. M. Lake, Kyle S. Hoffman et al. · ACS Chemical Biology Open access 6 May 2022 27
37 Through the eye of an electrospray needle: mass spectrometric identification of the major peptides and proteins in the milk of the one‐humped camel (Camelus dromedarius) Abdulqader A. Alhaider, Abdel Galil Abdelgader, Abdullah Arif Turjoman et al. · Journal of Mass Spectrometry 18 Jun 2013 27
38 A Disaggregated Packet Processing Architecture for Network Function Virtualization Shihabur Rahman Chowdhury, Anthony Anthony, Haibo Bian et al. · IEEE Journal on Selected Areas in Communications 8 Apr 2020 25
39 Analysis of iTRAQ data using Mascot and Peaks quantification algorithms Carla M. R. Lacerda, Lei Xin, Iain Rogers et al. · Briefings in Functional Genomics and Proteomics Open access 12 Feb 2008 24
40 An Effective Algorithm for the Peptide De Novo Sequencing from MS/MS Spectrum Bin Ma, Kaizhong Zhang, Chengzhi Liang · Lecture notes in computer science Conference paper 2003 23
41 ZOOM Lite: next-generation sequencing data mapping and visualization software Zhiwu S. Zhang, He Lin, Bin Ma · Nucleic Acids Research Open access 8 Jun 2010 19
42 Computational proteomics pitfalls and challenges: HavanaBioinfo 2012 Workshop report Yasset Pérez‐Riverol et al. · Journal of Proteomics 29 Jan 2013 19
43 A three-dimensional groundwater flow model of the Waterloo Moraine for water resource management Patricia A. Meyer, Martinus Brouwers, Paul J. Martin · Canadian Water Resources Journal / Revue canadienne des ressources hydriques Open access 3 Apr 2014 19
44 Bacterial translation machinery for deliberate mistranslation of the genetic code Oscar Vargas‐Rodriguez, Ahmed H. Badran, Kyle S. Hoffman et al. · Proceedings of the National Academy of Sciences Open access 19 Aug 2021 18
45 Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation sites Maxime Lorenzini, Sophie Burel, Adrien Lesage et al. · The Journal of General Physiology Open access 13 Nov 2020 18
46 DISGENET: Accelerating Data-Driven Discovery in Disease Genomics and Therapeutic Development Janet Piñero, Javier Corvi, Natalia Rykova et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 5 Jan 2026 15
47 A translational program that suppresses metabolism to shield the genome Nathan C. Balukoff, J.J.David Ho, Phaedra R. Theodoridis et al. · Nature Communications Open access 13 Nov 2020 15
48 Insights from four decades of model development on the Waterloo Moraine: A review Emil O. Frind, John W. Molson, Marcelo R. Sousa et al. · Canadian Water Resources Journal / Revue canadienne des ressources hydriques Open access 3 Apr 2014 15
49 Mistranslating the genetic code with leucine in yeast and mammalian cells Josephine Davey-Young, Farah Hasan, Rasangi Tennakoon et al. · RNA Biology Open access 17 Apr 2024 14
50 Mistranslation of the genetic code by a new family of bacterial transfer RNAs Dominik B. Schuntermann, Jonathan T. Fischer, Jonmatthew Bile et al. · Journal of Biological Chemistry Open access 22 May 2023 14

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.