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Most cited papers from BioInvent (Sweden)

What are the most cited papers from BioInvent (Sweden)?

The most cited paper from BioInvent (Sweden) is "Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies" (Frederick Arce Vargas et al., 2018), with 594 citations. Next come "Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries" (337) and "Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2–mediated heparin-binding EGF signaling in endothelial cells" (287).

Showing 50 of 61 papers. Every paper with more than 21 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies Frederick Arce Vargas et al. · Cancer Cell Open access255 authors 22 Mar 2018 594
2 Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries Eskil Söderlind, Leif Strandberg, Pernilla Jirholt et al. · Nature Biotechnology Aug 2000 337
3 Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2–mediated heparin-binding EGF signaling in endothelial cells Katrin J. Svensson, Paulina Kucharzewska, Helena C. Christianson et al. · Proceedings of the National Academy of Sciences Open access 25 Jul 2011 287
4 Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events Hamed Emami, Parmanand Singh, Megan H. MacNabb et al. · JACC. Cardiovascular imaging Open access 7 Jan 2015 264
5 Recombinant Antibodies to an Oxidized Low-Density Lipoprotein Epitope Induce Rapid Regression of Atherosclerosis in Apobec-1−/−/Low-Density Lipoprotein Receptor−/−Mice Alexandru Șchiopu, Björn Frendéus, Bo Jansson et al. · Journal of the American College of Cardiology Open access Dec 2007 180
6 Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function Sarah L. Buchan et al. · Immunity Open access Nov 2018 164
7 Antagonistic Human FcγRIIB (CD32B) Antibodies Have Anti-Tumor Activity and Overcome Resistance to Antibody Therapy In Vivo Ali Roghanian et al. · Cancer Cell Open access Apr 2015 135
8 Human peripheral blood lymphocytes transplanted into SCID mice constitute an in vivo culture system exhibiting several parameters found in a normal humoral immune response and are a source of immunocytes for the production of human monoclonal antibodies R. Carlsson, Christina Mårtensson, Suzanne Kalliomäki et al. · The Journal of Immunology Feb 1992 105
9 Internalization of Rituximab and the Efficiency of B Cell Depletion in Rheumatoid Arthritis and Systemic Lupus Erythematosus Venkat R Reddy, Geraldine Cambridge, David Alan Isenberg et al. · Arthritis & Rheumatology Open access 27 Apr 2015 102
10 Real Time Analysis of Antibody‐Antigen Reaction Kinetics Ann‐Christin Malmborg, Anne Michaelsson, Mats Ohlin et al. · Scandinavian Journal of Immunology Jun 1992 100
11 Microarrays based on affinity‐tagged single‐chain Fv antibodies: Sensitive detection of analyte in complex proteomes Christer Wingren, Cornelia Steinhauer, Johan Ingvarsson et al. · PROTEOMICS 24 Feb 2005 94
12 Design of Recombinant Antibody Microarrays for Serum Protein Profiling: Targeting of Complement Proteins Johan Ingvarsson, Anette Larsson, Anders G. Sjöholm et al. · Journal of Proteome Research 16 Aug 2007 91
13 Gefitinib Induces Epidermal Growth Factor Receptor Dimers Which Alters the Interaction Characteristics with 125I-EGF Hanna Björkelund, Lars Gedda, Pavel Bárta et al. · PLoS ONE Open access 12 Sep 2011 85
14 Exploiting sequence space: shuffling in vivo formed complementarity determining regions into a master framework Pernilla Jirholt, Mats Ohlin, Carl A.K. Borrebaeck et al. · Gene Jul 1998 84
15 Inhibitory FcγRIIb (CD32b) becomes activated by therapeutic mAb in both cis and trans and drives internalization according to antibody specificity Andrew T. Vaughan, Chisako Iriyama, Stephen A. Beers et al. · Blood 14 Nov 2013 78
16 Automated Screening Procedure for High-Throughput Generation of Antibody Fragments Johan Hallborn, Roland N.K. Carlsson · BioTechniques Open access Dec 2002 76
17 A Human ICAM-1 Antibody Isolated by a Function-First Approach Has Potent Macrophage-Dependent Antimyeloma Activity In Vivo Niina Veitonmäki, Markus Hansson, Fenghuang Zhan et al. · Cancer Cell Open access Apr 2013 74
18 Wood morphology and properties from molecular perspectives Lennart Salmén · Annals of Forest Science Open access 3 Jul 2014 73
19 LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation Muchaala Yeboah et al. · JCI Insight Open access Sep 2020 72
20 Serum from patients with systemic vasculitis induces alternatively activated macrophage M2c polarization Susanne M. Ohlsson, Petrus Linge, Birgitta Gullstrand et al. · Clinical Immunology 14 Mar 2014 70
21 Monoclonal Antibody TB-403: A First-in-Human, Phase I, Double-Blind, Dose Escalation Study Directed Against Placental Growth Factor in Healthy Male Subjects Titti Martinsson-Niskanen, Rikke Riisbro, Leonard Larsson et al. · Clinical Therapeutics Sep 2011 59
22 Targeting the Antibody Checkpoints to Enhance Cancer Immunotherapy–Focus on FcγRIIB Ingrid Teige, Linda Mårtensson, Björn Frendéus · Frontiers in Immunology Open access 12 Mar 2019 56
23 Upregulation of FcγRIIb on monocytes is necessary to promote the superagonist activity of TGN1412 Khiyam Hussain, Chantal E. Hargreaves, Ali Roghanian et al. · Blood Open access 14 Nov 2014 54
24 Human leukocyte immunoglobulin-like receptors in health and disease Silvia Redondo-García, Christopher Barritt, Charys Papagregoriou et al. · Frontiers in Immunology Open access 13 Nov 2023 52
25 The hijackers guide to escaping complement: Lessons learned from pathogens David Ermert, Sanjay Ram, Maisem Laabei · Molecular Immunology Open access 20 Jul 2019 52
26 A single-arm, open-label, phase 2 clinical trial evaluating disease response following treatment with BI-505, a human anti-intercellular adhesion molecule-1 monoclonal antibody, in patients with smoldering multiple myeloma Stina Wichert, Gunnar Juliusson, Åsa C. M. Johansson et al. · PLoS ONE Open access 3 Feb 2017 51
27 A phase I, dose-escalation study of TB-403, a monoclonal antibody directed against PlGF, in patients with advanced solid tumours Ulrik Lassen, Dorte Lisbet Nielsen, Morten Mau‐Sørensen et al. · British Journal of Cancer Open access 24 Jan 2012 50
28 A Phase I Dose-Escalation Study of Antibody BI-505 in Relapsed/Refractory Multiple Myeloma Markus Hansson, Peter Gimsing, Ashraf Z. Badros et al. · Clinical Cancer Research Open access 26 Feb 2015 49
29 Telomerase regulation and telomere dynamics in germinal centers Karl‐Fredrik Norrback, Magnus Hultdin, Katarina Dahlenborg et al. · European Journal Of Haematology Nov 2001 49
30 Targeting oxidized LDL improves insulin sensitivity and immune cell function in obese Rhesus macaques Shijie Li, Paul Kievit, Anna-Karin Robertson et al. · Molecular Metabolism Open access 11 Jun 2013 49
31 A new murine IgG1 anti-Tn monoclonal antibody with in vivo anti-tumor activity Charlotte Welinder, Bo Baldetorp, Carl A.K. Borrebaeck et al. · Glycobiology 5 Apr 2011 47
32 Development and Characterization of Monoclonal Antibodies Specific for Mouse and Human Fcγ Receptors Alison L. Tutt et al. · The Journal of Immunology 29 Oct 2015 44
33 Inhibition of injury-induced arterial remodelling and carotid atherosclerosis by recombinant human antibodies against aldehyde-modified apoB-100 Åsa Ström, Gunilla Nordin Fredrikson, Alexandru Șchiopu et al. · Atherosclerosis 9 May 2006 43
34 Human CD4+ T cells expressing CD45RA acquire the lymphokine gene expression of CD45RO+ T-helper cells after activation in vitro. Karin Kristensson, Carl A.K. Borrebaeck, R. Carlsson · PubMed Open access May 1992 40
35 Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes Anne Ljungars, Carolin Svensson, Anders Carlsson et al. · Frontiers in Pharmacology Open access 30 Jul 2019 37
36 Design of Recombinant Antibody Microarrays for Cell Surface Membrane Proteomics Linda Dexlin, Johan Ingvarsson, Björn Frendéus et al. · Journal of Proteome Research 30 Nov 2007 36
37 Therapeutic efficacy of a DNA vaccine targeting the endothelial tip cell antigen delta-like ligand 4 in mammary carcinoma B K Haller, Andreas Bråve, Elisabet Wallgard et al. · Oncogene 24 May 2010 35
38 Epitopes on CA 125 from Cervical Mucus and Ascites Fluid and Characterization of Six New Antibodies Kjell Nustad, Yuri S. Lebedin, Kenneth O. Lloyd et al. · Tumor Biology 2002 34
39 Therapeutic antibodies targeting angiomotin inhibit angiogenesis in vivo Tetyana Levchenko, Niina Veitonmäki, Andrea Lundkvist et al. · The FASEB Journal 5 Nov 2007 34
40 Methodologies for model calibration to assist the design of a preparative ion-exchange step for antibody purification David Karlsson, Niklas Jakobsson, Karl-Johan Brink et al. · Journal of Chromatography A 10 Feb 2004 33
41 Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject ‘cold’ tumors Monika Semmrich, Jean‐Baptiste Marchand, Laetitia Fend et al. · Journal for ImmunoTherapy of Cancer Open access 2022 32
42 HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy Khiyam Hussain et al. · Journal of Experimental & Clinical Cancer Research Open access 7 Apr 2022 31
43 Single intravenous administration of TB‐402 for the prophylaxis of venous thromboembolism after total knee replacement: a dose‐escalating, randomized, controlled trial Peter B. Verhamme, Marco J. D. Tangelder, Raymond Verhaeghe et al. · Journal of Thrombosis and Haemostasis Open access Feb 2011 31
44 Stimulation of proliferation in human colon cancer cells by human monoclonal antibodies against the TF antigen (galactose β1-3 N-acetyl-galactosamine) Lu‐Gang Yu, Bo Jansson, David Garth Fernig et al. · International Journal of Cancer 4 Nov 1997 30
45 A new look at drugs targeting malignant melanoma—An application for mass spectrometry imaging Yutaka Sugihara, Ákos Végvári, Charlotte Welinder et al. · PROTEOMICS 18 Jul 2014 29
46 Phenotypical and Functional Differentiation of CD4+ CD45RA+ Human T Cells Following Polyclonal Activation Karin Kristensson, Mikael Dohlsten, Hans Fischer et al. · Scandinavian Journal of Immunology Sep 1990 28
47 Domain binding and isotype dictate the activity of anti-human OX40 antibodies Jordana Griffiths et al. · Journal for ImmunoTherapy of Cancer Open access Dec 2020 27
48 Identification of the target for therapeutic recombinant anti-apoB-100 peptide antibodies in human atherosclerotic lesions Isabel Gonçalves, Mihaela Nitulescu, Mikko P.S. Ares et al. · Atherosclerosis Dec 2008 27
49 FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms Alexander P. Simpson, Ali Roghanian, Robert J. Oldham et al. · Cell Reports Open access Jul 2022 26
50 Rapid induction of apoptosis in B‐cell lymphoma by functionally isolated human antibodies Johan Fransson, Ulla‐Carin Tornberg, Carl A.K. Borrebaeck et al. · International Journal of Cancer Open access 13 Feb 2006 25

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.