Institution · Burroughs Wellcome Fund
Most cited papers from Burroughs Wellcome Fund
What are the most cited papers from Burroughs Wellcome Fund?
The most cited paper from Burroughs Wellcome Fund is "Generalized Formula for the Electric Tunnel Effect between Similar Electrodes Separated by a Thin Insulating Film" (John G. Simmons, 1963), with 4,170 citations. Next come "Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine Treatment" (3,755) and "A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary Hypertension" (2,711).
Showing 50 of 60 papers. Every paper with more than 238 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Generalized Formula for the Electric Tunnel Effect between Similar Electrodes Separated by a Thin Insulating Film John G. Simmons · Journal of Applied Physics | Jun 1963 | 4,170 |
| 2 | Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine Treatment Edward M. Connor, RHODA S. SPERLING, Richard D. Gelber et al. · New England Journal of Medicine | 3 Nov 1994 | 3,755 |
| 3 | A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary Hypertension Robyn J. Barst, Lewis J. Rubin, Walker A. Long et al. · New England Journal of Medicine | Feb 1996 | 2,711 |
| 4 | Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine Gertrude B. Elion, Phillip A. Furman, James A. Fyfe et al. · Proceedings of the National Academy of Sciences | Dec 1977 | 1,595 |
| 5 | Central Challenges Facing the National Clinical Research Enterprise Nancy S. Sung, William F. Crowley, Myron Genel et al. · JAMA | 12 Mar 2003 | 1,247 |
| 6 | 9-(2-Hydroxyethoxymethyl)guanine activity against viruses of the herpes group H. J. Schaeffer, Lilia M. Beauchamp, Paulo de Miranda et al. · Nature | 13 Apr 1978 | 1,141 |
| 7 | Electric Tunnel Effect between Dissimilar Electrodes Separated by a Thin Insulating Film John G. Simmons · Journal of Applied Physics | Sep 1963 | 950 |
| 8 | Association of Hormone-Replacement Therapy with Various Cardiovascular Risk Factors in Postmenopausal Women Azmi A. Nabulsi, Aaron R. Folsom, Alice White et al. · New England Journal of Medicine | 15 Apr 1993 | 914 |
| 9 | Withdrawal of Digoxin from Patients with Chronic Heart Failure Treated with Angiotensin-Converting-Enzyme Inhibitors Milton Packer, Mihai Gheorghiade, James B. Young et al. · New England Journal of Medicine | Jul 1993 | 835 |
| 10 | Termination detection for diffusing computations Edsger W. Dijkstra, Carel S. Schölten · Information Processing Letters | Aug 1980 | 690 |
| 11 | The Purine Path to Chemotherapy Gertrude B. Elion · Science | 7 Apr 1989 | 686 |
| 12 | Bupropion: a review of its mechanism of antidepressant activity. John A. Ascher, Jonathan O Cole, J. N. Colin et al. · PubMed | Sep 1995 | 686 |
| 13 | Resistance to ddI and Sensitivity to AZT Induced by a Mutation in HIV-1 Reverse Transcriptase M H St Clair, J L Martin, Gareth Tudor‐Williams et al. · Science | 27 Sep 1991 | 682 |
| 14 | Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells Joseph Schlessinger, Yoram Shechter, Mark C. Willingham et al. · Proceedings of the National Academy of Sciences | Jun 1978 | 646 |
| 15 | Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death. Victor E. Laubach, Edward G. Shesely, Oliver Smithies et al. · Proceedings of the National Academy of Sciences | 7 Nov 1995 | 588 |
| 16 | Validation and characterization of the L5178Y/TK+/- mouse lymphoma mutagen assay system Donald Clive, K. Johnson, J.F.S. Spector et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis | 1979 | 565 |
| 17 | Survival in Primary Pulmonary Hypertension with Long-Term Continuous Intravenous Prostacyclin Robyn J. Barst, Lewis J. Rubin, Michael D. McGoon et al. · Annals of Internal Medicine | 15 Sep 1994 | 554 |
| 18 | The ILLIAC IV Computer Greg Barnes, Rebecca M. Brown, M. Kato et al. · IEEE Transactions on Computers | Aug 1968 | 528 |
| 19 | Pharmaceutical hydrates Rajendra K. Khankari, David J.W. Grant · Thermochimica Acta | 1995 | 484 |
| 20 | A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells Veronica Sullivan, Christine L. Talarico, Sylvia C. Stanat et al. · Nature | 9 Jul 1992 | 479 |
| 21 | Funding for malaria genome sequencing Stephen L. Hoffman, William H. Bancroft, Gottlieb Michael et al. · Nature | 12 Jun 1997 | 478 |
| 22 | Effect of Continuous Intravenous Infusion of Zidovudine (AZT) in Children with Symptomatic HIV Infection Philip A. Pizzo, Janie Eddy, Judy Falloon et al. · New England Journal of Medicine | 6 Oct 1988 | 451 |
| 23 | A model for intracellular translocation of protein kinase C involving synergism between Ca2+ and phorbol esters Marlene Wolf, Harry LeVine, W. Stratford May et al. · Nature | Oct 1985 | 445 |
| 24 | Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Brian E. Huber, Elizabeth A. Austin, C A Richards et al. · Proceedings of the National Academy of Sciences | 16 Aug 1994 | 424 |
| 25 | The Relevance in Adults of Air-flow Obstruction, but not of Mucus Hypersecretion, to Mortality from Chronic Lung Disease Richárd Pető, Frank E. Speizer, A. L. Cochrane et al. · American Review of Respiratory Disease | Sep 1983 | 422 |
| 26 | Progressive Disease Due to Ganciclovir-Resistant Cytomegalovirus in Immunocompromised Patients Alejo Erice, Sunwen Chou, Karen K. Biron et al. · New England Journal of Medicine | 2 Feb 1989 | 408 |
| 27 | Pharmacokinetics of the acyclovir pro-drug valaciclovir after escalating single-and multiple-dose administration to normal volunteers S Weller, Martin Blum, Marna Doucette et al. · Clinical Pharmacology & Therapeutics | Dec 1993 | 397 |
| 28 | Numerical and Machine Solutions of Transient Heat-Conduction Problems Involving Melting or Freezing: Part I—Method of Analysis and Sample Solutions William Donald Murray, Fred Landis · ASME Journal of Heat and Mass Transfer | May 1959 | 387 |
| 29 | The Clinical Neuromuscular Pharmacology of Mivacurium Chloride (BW B1090U). A Short-acting Nondepolarizing Ester Neuromuscular Blocking Drug John J. Savarese, Hassan H. Ali, S. J. Basta et al. · Anesthesiology | May 1988 | 385 |
| 30 | Pharmacokinetics of acyclovir after intravenous and oral administration Paulo de Miranda, Martin Blum · Journal of Antimicrobial Chemotherapy | 1983 | 383 |
| 31 | An optimum character recognition system using decision functions C. K. Chow · IRE Transactions on Electronic Computers | Dec 1957 | 373 |
| 32 | Collection of insulin, EGF and α2-Macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization Frederick R. Maxfield, Joseph Schlessinger, Yoram Shechter et al. · Cell | Aug 1978 | 368 |
| 33 | Activation of a Cytosolic ADP-ribosyltransferase by Nitric Oxide-generating Agents Bernhard Brüne, E G Lapetina · Journal of Biological Chemistry | May 1989 | 362 |
| 34 | Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis J L Martin, Claire Brown, N Matthews-Davis et al. · Antimicrobial Agents and Chemotherapy | Dec 1994 | 343 |
| 35 | Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice. Carlos L. Arteaga, Libbey J. Kitten, Ester B. Coronado et al. · Journal of Clinical Investigation | Nov 1989 | 331 |
| 36 | Metabolic studies of allopurinol, an inhibitor of xanthine oxidase Gertrude B. Elion, Aylene Kovensky, George H. Hitchings et al. · Biochemical Pharmacology | Jul 1966 | 331 |
| 37 | Studies on the induction of CO-binding pigments in liver microsomes by phenobarbital and 3-methylcholanthrene Alvito P. Alvares, G. Schilling, Wayne Levin et al. · Biochemical and Biophysical Research Communications | Nov 1967 | 330 |
| 38 | Estrogenic action of DDT and its analogs Richard M. Welch, Wayne Levin, Allan H. Conney · Toxicology and Applied Pharmacology | Mar 1969 | 319 |
| 39 | Attenuation of p53 Expression Protects against Focal Ischemic Damage in Transgenic Mice R. Christian Crumrine, Amy L. Thomas, Philip F. Morgan · Journal of Cerebral Blood Flow & Metabolism | Nov 1994 | 314 |
| 40 | Recombinant Human Tumor Necrosis Factor Administered as a 24-Hour Intravenous Infusion. A Phase I and Pharmacologic Study D R Spriggs, Matthew Leigh Sherman, HAMISH R. MICHIE et al. · JNCI Journal of the National Cancer Institute | 7 Sep 1988 | 309 |
| 41 | A Controlled Trial of Acyclovir for Chickenpox in Normal Children Lisa M. Dunkle, Ann M. Arvin, Richard J. Whitley et al. · New England Journal of Medicine | 28 Nov 1991 | 308 |
| 42 | A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase. Eugene Y. Krynetski, John D. Schuetz, Amy J. Galpin et al. · Proceedings of the National Academy of Sciences | 14 Feb 1995 | 308 |
| 43 | Potentiation by inhibition of drug degradation : 6-substituted purines and xanthine oxidase Gertrude B. Elion, Sandra Callahan, Henry C. Nathan et al. · Biochemical Pharmacology | 1963 | 306 |
| 44 | Derivation of a termination detection algorithm for distributed computations Edsger W. Dijkstra, Wim H. J. Feijen, A. J. M. van Gasteren · Information Processing Letters | Jun 1983 | 303 |
| 45 | Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen Debra L. Laskin, Carol R. Gardner, Veronica F. Price et al. · Hepatology | Apr 1995 | 289 |
| 46 | Inhibitor Binding Analysis of Dihydrofolate Reductases from Various Species James J. Burchall, George H. Hitchings · Molecular Pharmacology | Sep 1965 | 287 |
| 47 | 3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase M H St Clair, C A Richards, T Spector et al. · Antimicrobial Agents and Chemotherapy | Dec 1987 | 282 |
| 48 | Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells. Susanna Cotecchia, Brian K. Kobilka, Kiefer W. Daniel et al. · Journal of Biological Chemistry | 1990 | 271 |
| 49 | Suppression of Subclinical Shedding of Herpes Simplex Virus Type 2 with Acyclovir Anna Wald, Judith Zeh, Gail Barnum et al. · Annals of Internal Medicine | 1996 | 267 |
| 50 | Hepatic Glutathione Homeostasis in the Rat: Efflux Accounts for Glutathione Turnover Bernhard H. Lauterburg, James David Adams Jr., Jerry R. Mitchell · Hepatology | Jul 1984 | 262 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.