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Most cited papers from Canada Research Chairs

What are the most cited papers from Canada Research Chairs?

The most cited paper from Canada Research Chairs is "Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice" (Fouad Shalaby, Janet Rossant, Terry P. Yamaguchi et al., 1995), with 3,971 citations. Next come "Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry" (3,631) and "Global landscape of protein complexes in the yeast Saccharomyces cerevisiae" (3,002).

Showing 50 of 60 papers. Every paper with more than 591 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice Fouad Shalaby, Janet Rossant, Terry P. Yamaguchi et al. · Nature Jul 1995 3,971
2 Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry Yuen Ho et al. · Nature 2002 3,631
3 Global landscape of protein complexes in the yeast Saccharomyces cerevisiae Nevan J. Krogan et al. · Nature Mar 2006 3,002
4 Human-level concept learning through probabilistic program induction Brenden M. Lake, Ruslan Salakhutdinov, Joshua B. Tenenbaum · Science 11 Dec 2015 2,969
5 Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium Guo‐Hua Fong, Janet Rossant, Marina Gertsenstein et al. · Nature Jul 1995 2,634
6 Gamification in theory and action: A survey Katie Seaborn, Deborah I. Fels · International Journal of Human-Computer Studies Open access 5 Oct 2014 2,499
7 A scoping review on the conduct and reporting of scoping reviews Andrea C. Tricco, Erin Lillie, Wasifa Zarin et al. · BMC Medical Research Methodology Open access 8 Feb 2016 2,311
8 Enhanced electrocatalytic CO2 reduction via field-induced reagent concentration Min Liu, Yuanjie Pang, Bo Zhang et al. · Nature 2 Aug 2016 2,006
9 Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles Timothy J. Nott, Evangelia Petsalaki, Patrick J. Farber et al. · Molecular Cell Open access Mar 2015 1,978
10 Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family P. Filippakopoulos, S. Picaud, Maria Mangos et al. · Cell Open access Mar 2012 1,794
11 Ligand-Stabilized Reduced-Dimensionality Perovskites Li Na Quan, Mingjian Yuan, Riccardo Comin et al. · Journal of the American Chemical Society 3 Feb 2016 1,442
12 Global Burden of Disease and the Impact of Mental and Addictive Disorders Jürgen T. Rehm, Kevin David Shield · Current Psychiatry Reports Feb 2019 1,439
13 Building devices from colloidal quantum dots Cherie R. Kagan, Efrat Lifshitz, Edward Hartley Sargent et al. · Science 25 Aug 2016 1,405
14 Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE Sushmita Mimi Roy et al. · Science Open access172 authors 23 Dec 2010 1,314
15 Declaración PRISMA 2020: una guía actualizada para la publicación de revisiones sistemáticas Matthew James Page et al. · Revista Española de Cardiología (English Edition) Open access 23 Aug 2021 1,291
16 The maternal-to-zygotic transition: a play in two acts Wael Tadros, Howard D. Lipshitz · Development Open access 21 Aug 2009 1,276
17 Interaction network containing conserved and essential protein complexes in Escherichia coli Gareth P. Butland, José Manuel Peregrín-Alvarez, Joyce Li et al. · Nature Feb 2005 1,220
18 Microbial and Animal Rhodopsins: Structures, Functions, and Molecular Mechanisms Oliver P. Ernst, David T. Lodowski, Marcus Elstner et al. · Chemical Reviews ReviewOpen access 23 Dec 2013 1,196
19 A scoping review of rapid review methods Andrea C. Tricco, Jesmin Antony, Wasifa Zarin et al. · BMC Medicine Open access 16 Sep 2015 1,188
20 Retinal Stem Cells in the Adult Mammalian Eye Vincent Tropepe, Brenda L.K. Coles, Bernard J. Chiasson et al. · Science 17 Mar 2000 1,086
21 Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016) John H. Duffus, Michael Schwenk, Douglas M. Templeton · Pure and Applied Chemistry Open access Aug 2016 1,080
22 Mitochondria, oxygen free radicals, disease and ageing Sandeep Raha, Brian Harford Robinson · Trends in Biochemical Sciences Review Oct 2000 1,075
23 Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project Mark Gerstein et al. · Science Open access131 authors 22 Dec 2010 1,044
24 Mechanism of hard-nanomaterial clearance by the liver Kim M. Tsoi, Sonya A. MacParland, Xue‐Zhong Ma et al. · Nature Materials Open access 15 Aug 2016 1,018
25 The NLR Gene Family: A Standard Nomenclature Jenny P.‐Y. Ting et al. · Immunity Open access Mar 2008 984
26 Interventions to reduce stress in university students: A review and meta-analysis Cheryl Regehr, Dylan Glancy, A. T. Pitts · Journal of Affective Disorders 14 Dec 2012 974
27 Deciphering the splicing code Yoseph Barash, John A. Calarco, Weijun Gao et al. · Nature May 2010 945
28 Subgroup-specific structural variation across 1,000 medulloblastoma genomes Paul A. Northcott et al. · Nature Open access135 authors 24 Jul 2012 936
29 Exploration of the Function and Organization of the Yeast Early Secretory Pathway through an Epistatic Miniarray Profile Maya Schuldiner, Sean R. Collins, Natalie Thompson et al. · Cell Open access Nov 2005 900
30 Classification of flexible manufacturing systems Jim Browne, Didier Dubois, Keith Rathmill et al. · HAL (Le Centre pour la Communication Scientifique Directe) PreprintOpen access 1984 860
31 A role for adult neurogenesis in spatial long-term memory Jason Scott Snyder, N.S. Hong, Robert J. McDonald et al. · Neuroscience 11 Dec 2004 857
32 Navigating the Chaperone Network: An Integrative Map of Physical and Genetic Interactions Mediated by the Hsp90 Chaperone Rongmin Zhao, Mike Davey, Ya‐Chieh Hsu et al. · Cell Open access Mar 2005 838
33 Cotranscriptional Set2 Methylation of Histone H3 Lysine 36 Recruits a Repressive Rpd3 Complex Michael‐Christopher Keogh, Siavash K. Kurdistani, Stephanie A. V. Morris et al. · Cell Open access Nov 2005 818
34 Synaptic plasticity in the anterior cingulate cortex in acute and chronic pain Tim Bliss, Graham L. Collingridge, Bong‐Kiun Kaang et al. · Nature reviews. Neuroscience Review 16 Jun 2016 817
35 A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains Manuel Irimia, Robert J. Weatheritt, Jonathan D. Ellis et al. · Cell Open access Dec 2014 776
36 Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication Piers Nash, Xiaojing Tang, Stephen M. Orlicky et al. · Nature 29 Nov 2001 771
37 The statistical significance of randomized controlled trial results is frequently fragile: a case for a Fragility Index Michael W. Walsh, Sadeesh Srinathan, Daniel Francis McAuley et al. · Journal of Clinical Epidemiology Open access 5 Feb 2014 767
38 Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism Neelroop Parikshak, Vivek Swarup, T. Grant Belgard et al. · Nature Open access 5 Dec 2016 765
39 Size-dependent DNA Mobility in Cytoplasm and Nucleus Gergely L. Lukács, Peter M. Haggie, Olivier Seksek et al. · Journal of Biological Chemistry Open access 2000 757
40 Finding the engram Sheena A. Josselyn, Stefan Köhler, Paul W. Frankland · Nature reviews. Neuroscience Review 20 Aug 2015 729
41 Dynamic modularity in protein interaction networks predicts breast cancer outcome Ian W. Taylor, Rune Linding, David Warde-Farley et al. · Nature Biotechnology Open access Feb 2009 718
42 Mapping Pathways and Phenotypes by Systematic Gene Overexpression Richelle Sopko, Dongqing Huang, Nicolle Preston et al. · Molecular Cell Open access Feb 2006 711
43 A Global Protein Kinase and Phosphatase Interaction Network in Yeast Ashton Breitkreutz, Hyungwon Choi, Jeffrey R. Sharom et al. · Science Open access 20 May 2010 701
44 Copy-number variations associated with neuropsychiatric conditions Edwin H. Cook, Stephen W. Scherer · Nature Oct 2008 680
45 Medulloblastomics: the end of the beginning Paul A. Northcott, David Jones, Marcel Kool et al. · Nature reviews. Cancer ReviewOpen access 23 Nov 2012 677
46 Crystal structure of metarhodopsin II Hui‐Woog Choe, Yong Ju Kim, Jung Hee Park et al. · Nature Mar 2011 674
47 Developing a comprehensive definition of sustainability Julia E. Moore, Alekhya Mascarenhas, Julie Bain et al. · Implementation Science Open access 2 Sep 2017 656
48 The HUPO PSI's Molecular Interaction format—a community standard for the representation of protein interaction data Henning Hermjakob et al. · Nature Biotechnology 30 Jan 2004 645
49 International society of sports nutrition position stand: caffeine and exercise performance Nanci S. Guest, Trisha A. VanDusseldorp, Michael T. Nelson et al. · Journal of the International Society of Sports Nutrition Open access 2 Jan 2021 643
50 The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix Kelly M. Colvin, Yasuhiko Irie, Catherine S. Tart et al. · Environmental Microbiology Open access 19 Dec 2011 631

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.