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Most cited papers from Canadian Blood Services

What are the most cited papers from Canadian Blood Services?

The most cited paper from Canadian Blood Services is "A Comparison of Aprotinin and Lysine Analogues in High-Risk Cardiac Surgery" (Dean A. Fergusson, Paul C. Hébert, C. David Mazer et al., 2008), with 1,156 citations. Next come "Updated international consensus report on the investigation and management of primary immune thrombocytopenia" (1,151) and "Platelet Transfusion: A Clinical Practice Guideline From the AABB" (1,002).

Showing 50 of 60 papers. Every paper with more than 221 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A Comparison of Aprotinin and Lysine Analogues in High-Risk Cardiac Surgery Dean A. Fergusson, Paul C. Hébert, C. David Mazer et al. · New England Journal of Medicine Open access 14 May 2008 1,156
2 Updated international consensus report on the investigation and management of primary immune thrombocytopenia Drew Provan et al. · Blood Advances Open access 26 Nov 2019 1,151
3 Platelet Transfusion: A Clinical Practice Guideline From the AABB Richard Max Kaufman et al. · Annals of Internal Medicine 10 Nov 2014 1,002
4 Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients Baweleta Isho et al. · Science Immunology Open access 8 Oct 2020 925
5 ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders Francesco Rodeghiero, Alberto Tosetto, Thomas C. Abshire et al. · Journal of Thrombosis and Haemostasis Open access 6 Jul 2010 887
6 Estimation of stage‐specific fibrosis progression rates in chronic hepatitis C virus infection Hla‐Hla Thein, Qilong Yi, Gregory J. Dore et al. · Hepatology Open access 18 Apr 2008 837
7 Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery C. David Mazer et al. · New England Journal of Medicine Open access 12 Nov 2017 781
8 Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Anna Janowska‐Wieczorek, Marcin Wysoczynski, Jacek Kijowski et al. · International Journal of Cancer Open access 23 Oct 2004 767
9 Transfusion-related immunomodulation (TRIM): An update Eleftherios C. Vamvakas, Morris A. Blajchman · Blood Reviews Open access 5 Sep 2007 663
10 Patient Blood Management Markus M. Mueller et al. · JAMA 12 Mar 2019 643
11 Migration of Bone Marrow and Cord Blood Mesenchymal Stem Cells In Vitro Is Regulated by Stromal‐Derived Factor‐1‐CXCR4 and Hepatocyte Growth Factor‐c‐met Axes and Involves Matrix Metalloproteinases Bo‐Ra Son, Leah A. Marquez‐Curtis, Magda Kucia et al. · Stem Cells 13 Jan 2006 641
12 Determination of Brain Death/Death by Neurologic Criteria David Matthew Greer et al. · JAMA 3 Aug 2020 640
13 Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention Eleftherios C. Vamvakas, Morris A. Blajchman · Blood 2 Feb 2009 627
14 Cell encapsulation: Promise and progress Gorka Orive, Rosa Marı́a Hernández, Alicia Rodríguez‐Gascón et al. · Nature Medicine Open access 2003 594
15 Clinical consequences of red cell storage in the critically ill Alan T. Tinmouth, Dean A. Fergusson, Ian Chin Yee et al. · Transfusion 27 Oct 2006 583
16 The premature infants in need of transfusion (pint) study: A randomized, controlled trial of a restrictive (LOW) versus liberal (HIGH) transfusion threshold for extremely low birth weight infants Haresh Murli Kirpalani, Robin K. Whyte, Chad C Andersen et al. · The Journal of Pediatrics 30 Aug 2006 582
17 The Shaping of Modern Human Immune Systems by Multiregional Admixture with Archaic Humans Laurent Abi‐Rached et al. · Science Open access 25 Aug 2011 565
18 Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP) Anne Zufferey, Rick Kapur, John W. Semple · Journal of Clinical Medicine Open access 9 Feb 2017 563
19 Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner Marcin Majka, Anna Janowska‐Wieczorek, Janina Ratajczak et al. · Blood Open access 15 May 2001 505
20 Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo Rukhsana Aslam, Edwin R. Speck, Michael D. Kim et al. · Blood Open access 23 Sep 2005 479
21 One million haemopoietic stem-cell transplants: a retrospective observational study Alois A. Gratwohl et al. · The Lancet Haematology 26 Feb 2015 443
22 Deleterious clinical effects of transfusion-associated immunomodulation: fact or fiction? Eleftherios C. Vamvakas, Morris A. Blajchman · Blood Mar 2001 425
23 Natural history of hepatitis C virus infection in HIV-infected individuals and the impact of HIV in the era of highly active antiretroviral therapy: a meta-analysis Hla‐Hla Thein, Qilong Yi, Gregory J. Dore et al. · AIDS Review 10 Sep 2008 409
24 Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia June Li, Dianne E. van der Wal, Guangheng Zhu et al. · Nature Communications Open access 17 Jul 2015 386
25 Fostamatinib for the treatment of adult persistent and chronic immune thrombocytopenia: Results of two phase 3, randomized, placebo‐controlled trials James Bruce Bussel, Donald M. Arnold, Elliot Grossbard et al. · American Journal of Hematology Open access 26 Apr 2018 369
26 Mesenchymal stromal cells derived from various tissues: Biological, clinical and cryopreservation aspects Leah A. Marquez‐Curtis, Anna Janowska‐Wieczorek, Locksley E. McGann et al. · Cryobiology Open access 14 Jul 2015 364
27 Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond Xiaohong Xu, Dan Zhang, Brigitta Elaine Oswald et al. · Critical Reviews in Clinical Laboratory Sciences Review 10 Jun 2016 353
28 Proceedings of a Consensus Conference: Towards an Understanding of TRALI Mindy Goldman, Kathryn Elizabeth Webert, Donald M. Arnold et al. · Transfusion Medicine Reviews 2005 353
29 Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment Anna Janowska‐Wieczorek, Marcin Majka, Jacek Kijowski et al. · Blood 15 Nov 2001 352
30 Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review Cindy E. Neunert, Nastaran Noroozi, Geoff R. Norman et al. · Journal of Thrombosis and Haemostasis ReviewOpen access 12 Dec 2014 346
31 Effects of the COVID-19 pandemic on supply and use of blood for transfusion Simon J. Stanworth, Helen V. New, Torunn Oveland Apelseth et al. · The Lancet Haematology Open access 3 Jul 2020 337
32 The Frequency and Clinical Significance of Thrombocytopenia Complicating Critical Illness Phil Hui, Deborah J. Cook, Wendy Lim et al. · CHEST Journal 11 Nov 2010 336
33 Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells ‘hide out’ in the bone marrow Mariusz Z. Ratajczak, Magda Kucia, Ryan Reca et al. · Leukemia Open access 30 Oct 2003 328
34 Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents Xiaohong Xu, George Makram Yousef, Heyu Ni · Blood 8 Mar 2018 327
35 Effect of Short-Term vs. Long-Term Blood Storage on Mortality after Transfusion Nancy M. Heddle, Richard J. Cook, Donald M. Arnold et al. · New England Journal of Medicine 24 Oct 2016 327
36 Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial Harold L. Atkins et al. · The Lancet 12 Jun 2016 327
37 Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells Monika Baj‐Krzyworzeka, Marcin Majka, Domenico Praticò et al. · Experimental Hematology Open access May 2002 326
38 COVID-19 pandemic and worldwide organ transplantation: a population-based study Olivier Aubert et al. · The Lancet Public Health Open access 30 Aug 2021 315
39 Hematopoietic stem cell transplantation activity worldwide in 2012 and a SWOT analysis of the Worldwide Network for Blood and Marrow Transplantation Group including the global survey Dietger Niederwieser et al. · Bone Marrow Transplantation Open access 22 Feb 2016 312
40 Platelets and innate immunity John W. Semple, John J Freedman · Cellular and Molecular Life Sciences Open access 17 Dec 2009 308
41 CXCR4–SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion Jolanta Libura, Justyna Drukała, Marcin Majka et al. · Blood Open access 18 Sep 2002 305
42 Enhancing the Migration Ability of Mesenchymal Stromal Cells by Targeting the SDF-1/CXCR4 Axis Leah A. Marquez‐Curtis, Anna Janowska‐Wieczorek · BioMed Research International Open access 2013 291
43 Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles Fidel Martínez‐Gutiérrez, Emily P. Thi, Judith M. Silverman et al. · Nanomedicine Nanotechnology Biology and Medicine 30 Jun 2011 286
44 International guideline development for the determination of death Sam D. Shemie, Laura Hornby, ANDREW J. BAKER et al. · Intensive Care Medicine Open access 24 Mar 2014 277
45 Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial Philippe Bégin et al. · Nature Medicine Open access629 authors 9 Sep 2021 275
46 Of mice and men: an open-label pilot study for treatment of immune thrombocytopenic purpura by an inhibitor of Syk Anna J. Podolanczuk, Alan H. Lazarus, Andrew R. Crow et al. · Blood 18 Dec 2008 274
47 In vitro biological evaluation of high molecular weight hyperbranched polyglycerols Rajesh Kumar Kainthan, Samuel R. Hester, E.J. Levin et al. · Biomaterials 4 Aug 2007 273
48 Effects of storage on efficacy of red cell transfusion: When is it not safe? Julie Ho, William J. Sibbald, Ian H Chin-Yee · Critical Care Medicine Dec 2003 255
49 Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient Marcin Wysoczynski, Ryan Reca, Janina Ratajczak et al. · Blood 25 Aug 2004 252
50 Intravenous immunoglobulin ameliorates ITP via activating Fcγ receptors on dendritic cells Vinayakumar Siragam, Andrew R. Crow, Davor Brinc et al. · Nature Medicine 21 May 2006 246

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.