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Most cited papers from Cantox Health Sciences International

What are the most cited papers from Cantox Health Sciences International?

The most cited paper from Cantox Health Sciences International is "A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties" (Melody Harwood, Barbara Danielewska-Nikiel, Joseph F. Borzelleca et al., 2007), with 892 citations. Next come "Correlation of structural class with no-observed-effect levels: A proposal for establishing a threshold of concern" (501) and "Pulmonary applications and toxicity of engineered nanoparticles" (308).

Showing 50 of 59 papers. Every paper with more than 45 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties Melody Harwood, Barbara Danielewska-Nikiel, Joseph F. Borzelleca et al. · Food and Chemical Toxicology 8 Jun 2007 892
2 Correlation of structural class with no-observed-effect levels: A proposal for establishing a threshold of concern Ian C. Munro, Richard A. Ford, Elke Kennepohl et al. · Food and Chemical Toxicology Sep 1996 501
3 Pulmonary applications and toxicity of engineered nanoparticles Jeffrey W. Card, Darryl C. Zeldin, James C. Bonner et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology Open access 18 Jul 2008 308
4 Threshold of toxicological concern for chemical substances present in the diet: A practical tool for assessing the need for toxicity testing R. Kroes, Corrado Lodovico Galli, Ian C. Munro et al. · Food and Chemical Toxicology Feb 2000 277
5 Aspartame: Review of Safety Harriett H. Butchko et al. · Regulatory Toxicology and Pharmacology Apr 2002 246
6 Erythritol: an interpretive summary of biochemical, metabolic, toxicological and clinical data Ian C. Munro, W.O. Bernt, Joseph F. Borzelleca et al. · Food and Chemical Toxicology Dec 1998 215
7 A Brief Review of the Occurrence, Use, and Safety of Food‐Related Nanomaterials Bernadene A. Magnuson, Tomas S. Jonaitis, Jeffrey W. Card · Journal of Food Science Aug 2011 207
8 The FEMA GRAS assessment of benzyl derivatives used as flavor ingredients Timothy B. Adams, Samuel M. Cohen, John Doull et al. · Food and Chemical Toxicology 29 Jan 2005 201
9 Biochemical and Molecular Aspects of Mammalian Susceptibility to Aflatoxin B1 Carcinogenicity Thomas E. Massey, Richard K. Stewart, Jonathan M. Daniels et al. · Experimental Biology and Medicine Mar 1995 200
10 The Threshold of Toxicological Concern (TTC) in risk assessment Ian C. Munro, ANDREW G. RENWICK, Barbara Danielewska-Nikiel · Toxicology Letters 24 May 2008 199
11 A comparison of the LDL-cholesterol lowering efficacy of plant stanols and plant sterols over a continuous dose range: Results of a meta-analysis of randomized, placebo-controlled trials Kathy Musa‐Veloso, Theresa H. Poon, Julie Ann Elliot et al. · Prostaglandins Leukotrienes and Essential Fatty Acids Review 23 Feb 2011 194
12 Vitamin D and Sterol Composition of 10 Types of Mushrooms from Retail Suppliers in the United States Katherine M. Phillips, David M. Ruggio, Ronald L. Horst et al. · Journal of Agricultural and Food Chemistry 13 Jun 2011 184
13 A Comprehensive, Integrated Review and Evaluation of the Scientific Evidence Relating to the Safety of the Herbicide 2,4-D Ian C. Munro, George L. Carlo, Joan C. Orr et al. · Journal of the American College of Toxicology Open access Sep 1992 150
14 The FEMA GRAS assessment of cinnamyl derivatives used as flavor ingredients Timothy B. Adams, Samuel M. Cohen, John Doull et al. · Food and Chemical Toxicology 29 Oct 2003 149
15 A procedure for the safety evaluation of flavouring substances Ian C. Munro, Elke Kennepohl, R. Kroes · Food and Chemical Toxicology Feb 1999 147
16 Recommended protocols based on a survey of current practice in genotoxicity testing laboratories, IV. Chromosome aberration and sister-chromatid exchange in Chinese hamster ovary, V79 Chinese hamster lung and human lymphocyte cultures Sabine H. H. Swierenga, John A. Heddle, E.A. Sigal et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis Feb 1991 146
17 An overview of the safety of sucralose V. Lee Grotz, Ian C. Munro · Regulatory Toxicology and Pharmacology 22 May 2009 144
18 Defining a Noncarcinogenic Dose of Recombinant Human Parathyroid Hormone 1–84 in a 2-Year Study in Fischer 344 Rats Jacquelin Jolette, Clynn E. Wilker, Susan Y. Smith et al. · Toxicologic Pathology Dec 2006 142
19 Evaluation of the potential in vivo genotoxicity of quercetin Dietmar Utesch, K. Feige, Johannes Dasenbrock et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis 4 May 2008 140
20 Carcinogenicity of Monochloro-1,2-Propanediol (α-Chlorohydrin, 3-MCPD) Barry S. Lynch, Douglas W. Bryant, Graham J. Hook et al. · International Journal of Toxicology Open access 1998 136
21 Safety assessment of γ-cyclodextrin Ian C. Munro, Paul M. Newberne, V. R. Young et al. · Regulatory Toxicology and Pharmacology Jun 2004 133
22 Safety evaluation of α-lipoic acid (ALA) Dirk Cremer, R. Rabeler, Ashley S. Roberts et al. · Regulatory Toxicology and Pharmacology 15 Aug 2006 131
23 The FEMA GRAS Assessment of trans-Anethole Used as a Flavouring Substance Paul M. Newberne, Robert L. Smith, John Doull et al. · Food and Chemical Toxicology Jul 1999 128
24 Mechanisms for Sweetness John D. Fernstrom, Steven D. Munger, Anthony J. Sclafani et al. · Journal of Nutrition Open access 10 May 2012 114
25 The FEMA GRAS assessment of aliphatic and aromatic terpene hydrocarbons used as flavor ingredients Timothy B. Adams, C. Lucas Gavin, Margaret M. McGowen et al. · Food and Chemical Toxicology Open access 26 Jun 2011 114
26 Vitamin D Mushrooms: Comparison of the Composition of Button Mushrooms (Agaricus bisporus) Treated Postharvest with UVB Light or Sunlight Ryan R. Simon, Katherine M. Phillips, Ronald L. Horst et al. · Journal of Agricultural and Food Chemistry 8 Jul 2011 112
27 Erythritol: A Review of Biological and Toxicological Studies W.O. Bernt, Joseph F. Borzelleca, G. Flamm et al. · Regulatory Toxicology and Pharmacology Oct 1996 112
28 The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients Timothy B. Adams, John Doull, VICTOR J. FERON et al. · Food and Chemical Toxicology Apr 2002 104
29 A comprehensive review of oral glucosamine use and effects on glucose metabolism in normal and diabetic individuals Ryan R. Simon, Vincent Marks, Anthony Leeds et al. · Diabetes/Metabolism Research and Reviews Open access 7 Dec 2010 99
30 Long-term safety of α-lipoic acid (ALA) consumption: A 2-year study Dirk Cremer, R. Rabeler, Ashley S. Roberts et al. · Regulatory Toxicology and Pharmacology 9 Aug 2006 98
31 Evaluation of safety and human tolerance of the oral probiotic Streptococcus salivarius K12: A randomized, placebo-controlled, double-blind study Jeremy P. Burton, S. Cowley, Ryan R. Simon et al. · Food and Chemical Toxicology 26 Jun 2011 95
32 Toxicology Review and Risk Assessment of Resorcinol: Thyroid Effects Barry S. Lynch, Elizabeth Delzell, David H. Bechtel · Regulatory Toxicology and Pharmacology Oct 2002 94
33 An appraisal of the published literature on the safety and toxicity of food-related nanomaterials Jeffrey W. Card, Tomas S. Jonaitis, Shahrzad Tafazoli et al. · Critical Reviews in Toxicology 16 Nov 2010 87
34 Comparative toxicokinetics and metabolism of rebaudioside A, stevioside, and steviol in rats Ashley S. Roberts, Alistair G.C. Renwick · Food and Chemical Toxicology 17 May 2008 85
35 Subchronic toxicity of rebaudioside A Leslie L. Curry, Ashley S. Roberts · Food and Chemical Toxicology 17 May 2008 85
36 Toxicological Significance of DNA Adducts: Summary of Discussions with an Expert Panel Earle R. Nestmann, Douglas W. Bryant, C.Jelleff Carr et al. · Regulatory Toxicology and Pharmacology Aug 1996 84
37 A Method to Assess the Quality of Studies That Examine the Toxicity of Engineered Nanomaterials Jeffrey W. Card, Bernadene A. Magnuson · International Journal of Toxicology Jul 2010 82
38 A randomized, double-blinded, placebo-controlled oral challenge study to evaluate the allergenicity of commercial, food-grade fish gelatin T. K. Hansen, Lars Kaergaard Poulsen, Per Stahl Skov et al. · Food and Chemical Toxicology 4 Oct 2004 78
39 Evaluation of short-term and subchronic toxicity of magnolia bark extract in rats Zhaoping Liu, Xiaopeng Zhang, Wenming Cui et al. · Regulatory Toxicology and Pharmacology 5 Jul 2007 77
40 Low level laser therapy for healing acute and chronic wounds – the extendicare experience Anita E. Saltmarche · International Wound Journal Open access May 2008 76
41 Long-chain omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid dose-dependently reduce fasting serum triglycerides Kathy Musa‐Veloso, Malcolm A. Binns, Alexandra Catherine Kocenas et al. · Nutrition Reviews 24 Feb 2010 73
42 An Evaluation of the Possible Carcinogenicity of Bisphenol A to Humans Lois A. Haighton, Jason J. Hlywka, John Doull et al. · Regulatory Toxicology and Pharmacology Apr 2002 68
43 Generally recognized as safe (GRAS) evaluation of 4-hexylresorcinol for use as a processing aid for prevention of melanosis in shrimp Vasilios H. Frankos, Donald F. Schmitt, Laurie C. Haws et al. · Regulatory Toxicology and Pharmacology Oct 1991 66
44 Criteria for the safety evaluation of flavoring substances Robert L. Smith, Samuel M. Cohen, John Doull et al. · Food and Chemical Toxicology 19 Apr 2005 65
45 Acute, subchronic and genotoxicity studies conducted with Oligonol, an oligomerized polyphenol formulated from lychee and green tea extracts Hajime Fujii, Hiroshi Nishioka, Koji Wakame et al. · Food and Chemical Toxicology 19 Jun 2008 64
46 Vitamin D4 in Mushrooms Katherine M. Phillips, Ronald L. Horst, Nicholas J. Koszewski et al. · PLoS ONE Open access 3 Aug 2012 62
47 Evaluation of the in vitro and in vivo genotoxicity of magnolia bark extract Ning Li, Yan Song, Wenzhong Zhang et al. · Regulatory Toxicology and Pharmacology 5 Jul 2007 61
48 A reassessment of risk associated with dietary intake of ochratoxin A based on a lifetime exposure model Lois A. Haighton, Barry S. Lynch, Bernadene A. Magnuson et al. · Critical Reviews in Toxicology Open access 25 Jan 2012 61
49 Impact of low v. moderate intakes of long-chain n-3 fatty acids on risk of coronary heart disease Kathy Musa‐Veloso, Malcolm A. Binns, Alexandra Catherine Kocenas et al. · British Journal Of Nutrition Open access 31 May 2011 60
50 The FEMA GRAS assessment of hydroxy- and alkoxy-substituted benzyl derivatives used as flavor ingredients Timothy B. Adams, Samuel M. Cohen, John Doull et al. · Food and Chemical Toxicology 2 Apr 2005 57

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.