| 1 |
High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents
Junyi Ma, Liang Guo, Steve Fiene et al. · American Journal of Physiology-Heart and Circulatory Physiology
Open access |
3 Sep 2011 |
805 |
| 2 |
Extracellular Matrix Promotes Highly Efficient Cardiac Differentiation of Human Pluripotent Stem Cells
Jianhua Zhang, Matthew Klos, Gisela F. Wilson et al. · Circulation Research
Open access |
22 Aug 2012 |
456 |
| 3 |
International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment
Ksenia Blinova et al. · Cell Reports
Open access |
Sep 2018 |
382 |
| 4 |
Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs
Ruchi Sharma et al. · Science Translational Medicine
Open access |
16 Jan 2019 |
375 |
| 5 |
Quality Control Guidelines for Clinical-Grade Human Induced Pluripotent Stem Cell Lines
Stephen K. Sullivan et al. · Regenerative Medicine
Open access |
12 Sep 2018 |
284 |
| 6 |
Efficient Feeder-Free Episomal Reprogramming with Small Molecules
Junying Yu, Kevin Fongching Chau, Maxim A. Vodyanik et al. · PLoS ONE
Open access |
Mar 2011 |
257 |
| 7 |
Disease Modeling and Phenotypic Drug Screening for Diabetic Cardiomyopathy using Human Induced Pluripotent Stem Cells
Faye Drawnel et al. · Cell Reports
Open access |
30 Oct 2014 |
248 |
| 8 |
FGF2 Sustains NANOG and Switches the Outcome of BMP4-Induced Human Embryonic Stem Cell Differentiation
Pengzhi Yu, Guangjin Pan, Junying Yu et al. · Cell stem cell
Open access |
Mar 2011 |
248 |
| 9 |
Blood-Derived Human iPS Cells Generate Optic Vesicle–Like Structures with the Capacity to Form Retinal Laminae and Develop Synapses
M. Joseph Phillips, Kyle A. Wallace, Sarah Dickerson et al. · Investigative Ophthalmology & Visual Science
Open access |
13 Mar 2012 |
206 |
| 10 |
Multiparameter In Vitro Assessment of Compound Effects on Cardiomyocyte Physiology Using iPSC Cells
Oksana Sirenko, Carole Crittenden, Nick Callamaras et al. · SLAS DISCOVERY
Open access |
13 Sep 2012 |
181 |
| 11 |
Characterization of Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes: Bioenergetics and Utilization in Safety Screening
Payal Rana, Blake D. Anson, Sandra J. Engle et al. · Toxicological Sciences
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27 Jul 2012 |
169 |
| 12 |
Development and characterization of a scaffold-free 3D spheroid model of iPSC-derived human cardiomyocytes
Philippe Beauchamp, Nina D. Ullrich, Jens, Kelm et al. · BORIS (University Library Bern)
Open access |
Aug 2015 |
166 |
| 13 |
Development and Characterization of a Scaffold-Free 3D Spheroid Model of Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes
Philippe Beauchamp, Wolfgang Moritz, Jens M. Kelm et al. · Tissue Engineering Part C Methods
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5 Feb 2015 |
163 |
| 14 |
Derivation of Induced Pluripotent Stem Cells from Human Peripheral Blood T Lymphocytes
Matthew E. Brown, Elizabeth Rondon, Deepika Rajesh et al. · PLoS ONE
Open access |
29 Jun 2010 |
162 |
| 15 |
Opportunities for Use of Human iPS Cells in Predictive Toxicology
Blake D. Anson, Kyle L. Kolaja, Timothy J. Kamp · Clinical Pharmacology & Therapeutics
Open access |
23 Mar 2011 |
145 |
| 16 |
Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study
Daniel C. Millard, Qianyu Dang, Hong Shi et al. · Toxicological Sciences
Open access |
26 Apr 2018 |
134 |
| 17 |
Modeling Human Retinal Development with Patient-Specific Induced Pluripotent Stem Cells Reveals Multiple Roles for Visual System Homeobox 2
M. Joseph Phillips, Enio T. Perez, Jessica M. Martin et al. · Stem Cells
Open access |
17 Feb 2014 |
127 |
| 18 |
Human Vascular Tissue Models Formed from Human Induced Pluripotent Stem Cell Derived Endothelial Cells
David G. Belair, Jordan A. Whisler, Jorge Valdez et al. · Stem Cell Reviews and Reports
Open access |
4 Sep 2014 |
121 |
| 19 |
In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model
Oksana Sirenko, Fabian Alexander Grimm, Kristen Ryan et al. · Toxicology and Applied Pharmacology
Open access |
Mar 2017 |
117 |
| 20 |
An Epilepsy-Associated KCNT1 Mutation Enhances Excitability of Human iPSC-Derived Neurons by Increasing Slack KNa Currents
Imran H. Quraishi, Shani Stern, Kile P. Mangan et al. · Journal of Neuroscience
Open access |
26 Jul 2019 |
116 |
| 21 |
Morphological and Functional Characterization and Assessment of iPSC-Derived Hepatocytes forIn VitroToxicity Testing
Jingtao Lu, Shannon Einhorn, Lata Venkatarangan et al. · Toxicological Sciences
Open access |
18 Jun 2015 |
116 |
| 22 |
Prevention of β-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events
Xiaohong Xu, Ying Lei, Jie Luo et al. · Stem Cell Research
Open access |
7 Dec 2012 |
113 |
| 23 |
Generation of Induced Pluripotent Stem Cells from CD34+ Cells across Blood Drawn from Multiple Donors with Non-Integrating Episomal Vectors
Amanda A. Mack, Stacie L. Kroboth, Deepika Rajesh et al. · PLoS ONE
Open access |
22 Nov 2011 |
112 |
| 24 |
Phenotypic Screening with Human iPS Cell–Derived Cardiomyocytes: HTS-Compatible Assays for Interrogating Cardiac Hypertrophy
Coby B. Carlson, Chad H. Koonce, Natsuyo Aoyama et al. · SLAS DISCOVERY
Open access |
27 Sep 2013 |
107 |
| 25 |
Future Economics of Liver Transplantation: A 20-Year Cost Modeling Forecast and the Prospect of Bioengineering Autologous Liver Grafts
Dany Habka, David Ames Mann, Ronald Landes et al. · PLoS ONE
Open access |
15 Jul 2015 |
106 |
| 26 |
Phenotypic Characterization of Toxic Compound Effects on Liver Spheroids Derived from iPSC Using Confocal Imaging and Three-Dimensional Image Analysis
Oksana Sirenko, Michael K. Hancock, Jayne Hesley et al. · Assay and Drug Development Technologies
Open access |
5 Aug 2016 |
101 |
| 27 |
Determination of the Human Cardiomyocyte mRNA and miRNA Differentiation Network by Fine-Scale Profiling
Joshua Babiarz, Morgane Ravon, Sriram Sridhar et al. · Stem Cells and Development
Open access |
3 Nov 2011 |
96 |
| 28 |
Human Stem Cell-Derived Cardiomyocytes in Cellular Impedance Assays: Bringing Cardiotoxicity Screening to the Front Line
Matthew F. Peters, Sarah D. Lamore, Liang Guo et al. · Cardiovascular Toxicology
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18 Aug 2014 |
91 |
| 29 |
Extracellular vesicles from human cardiovascular progenitors trigger a reparative immune response in infarcted hearts
Bruna Lima Correa et al. · Cardiovascular Research
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3 Feb 2020 |
88 |
| 30 |
Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells
Megan M. Augustin, Dan R. Ruzicka, Ashutosh Kumar Shukla et al. · The Plant Journal
Open access |
2 May 2015 |
87 |
| 31 |
Pompe Disease Results in a Golgi-based Glycosylation Deficit in Human Induced Pluripotent Stem Cell-derived Cardiomyocytes
Kunil K. Raval, Ran Tao, Brent E. White et al. · Journal of Biological Chemistry
Open access |
9 Dec 2014 |
86 |
| 32 |
Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo
Dustin R. Wakeman, Benjamin M. Hiller, David J. Marmion et al. · Stem Cell Reports
Open access |
2 Jun 2017 |
85 |
| 33 |
Novel Application of Human Neurons Derived from Induced Pluripotent Stem Cells for Highly Sensitive Botulinum Neurotoxin Detection
Regina C. M. Whitemarsh, Monica J. Strathman, Lucas G. Chase et al. · Toxicological Sciences
Open access |
5 Jan 2012 |
84 |
| 34 |
Mesenchymal Stem Cell Assays and Applications
Mohan C. Vemuri, Lucas G. Chase, Mahendra S. Rao · Methods in molecular biology
Book chapter |
2011 |
84 |
| 35 |
Gating interaction maps reveal a noncanonical electromechanical coupling mode in the Shaker K+ channel
Ana Isabel Fernández-Mariño, Tyler J. Harpole, Kevin Oelstrom et al. · Nature Structural & Molecular Biology
Open access |
26 Mar 2018 |
77 |
| 36 |
Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities
Francesca Pistollato, Elan Liss Ohayon, Ann Lam et al. · Oncotarget
Open access |
4 May 2016 |
76 |
| 37 |
A high-throughput siRNA library screen identifies osteogenic suppressors in human mesenchymal stem cells
Yuanxiang Zhao, Sheng Ding · Proceedings of the National Academy of Sciences
Open access |
29 May 2007 |
76 |
| 38 |
A Defined, Feeder-Free, Serum-Free System to Generate In Vitro Hematopoietic Progenitors and Differentiated Blood Cells from hESCs and hiPSCs
Giorgia Salvagiotto, Sarah Burton, Christine A. Daigh et al. · PLoS ONE
Open access |
18 Mar 2011 |
71 |
| 39 |
Prediction of Drug Permeability Using In Vitro Blood–Brain Barrier Models with Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells
Makiko Ohshima, S. Kamei, Hideo Fushimi et al. · BioResearch open access
Open access |
Nov 2019 |
70 |
| 40 |
Human lymphoblastoid B-cell lines reprogrammed to EBV-free induced pluripotent stem cells
Deepika Rajesh, Sarah Dickerson, Junying Yu et al. · Blood
Open access |
28 Jun 2011 |
67 |
| 41 |
Human induced pluripotent stem cell-derived hepatocytes for toxicology testing
David Ames Mann · Expert Opinion on Drug Metabolism & Toxicology
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11 Nov 2014 |
65 |
| 42 |
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients
Shani Stern et al. · npj Parkinson s Disease
Open access |
10 Aug 2022 |
62 |
| 43 |
GMP‐Compliant Process for the Manufacturing of an Extracellular Vesicles‐Enriched Secretome Product Derived From Cardiovascular Progenitor Cells Suitable for a Phase I Clinical Trial
Camille Humbert, Chloé Cordier, Iouri Drut et al. · Journal of Extracellular Vesicles
Open access |
Aug 2025 |
60 |
| 44 |
Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells
Claus Rieker, Eugenia Migliavacca, Angélique Vaucher et al. · Arteriosclerosis Thrombosis and Vascular Biology
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18 Jul 2019 |
60 |
| 45 |
Feasibility, Safety, and Tolerance of Mesenchymal Stem Cell Therapy for Obstructive Chronic Lung Allograft Dysfunction
Cesar A. Keller, Thomas A. Gonwa, David O. Hodge et al. · Stem Cells Translational Medicine
Open access |
11 Jan 2018 |
59 |
| 46 |
Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells
Jung‐Hyun Kim et al. · Stem Cells Translational Medicine
Open access |
24 Oct 2017 |
57 |
| 47 |
Flexible and dynamic nucleosome fiber in living mammalian cells
Tadasu Nozaki, Kazunari Kaizu, Chan‐Gi Pack et al. · Nucleus
Open access |
29 Aug 2013 |
54 |
| 48 |
RNA Expression Profiling of Human iPSC-Derived Cardiomyocytes in a Cardiac Hypertrophy Model
Praful Aggarwal, Amy Jane Turner, Andrea M. Matter et al. · PLoS ONE
Open access |
25 Sep 2014 |
54 |
| 49 |
Stem Cells and Their Derivatives: A Renaissance in Cardiovascular Translational Research
Steven J. Kattman, Chad H. Koonce, Bradley Jay Swanson et al. · Journal of Cardiovascular Translational Research
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8 Nov 2010 |
49 |
| 50 |
Comparative Gene Expression Profiling in Human-Induced Pluripotent Stem Cell—Derived Cardiocytes and Human and Cynomolgus Heart Tissue
Dinesh Puppala, Leon P. Collis, Sunny Z. Sun et al. · Toxicological Sciences
Open access |
14 Sep 2012 |
49 |