Most cited papers from Center for Clinical & Basic Research
What are the most cited papers from Center for Clinical & Basic Research?
The most cited paper from Center for Clinical & Basic Research is "The diagnosis of osteoporosis" (John A. Professor Kanis, L. Joseph Melton, Claus Christiansen et al., 1994), with 3,904 citations. Next come "Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis" (3,503) and "Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes" (2,303).
Showing 50 of 60 papers. Every paper with more than 254 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | The diagnosis of osteoporosis John A. Professor Kanis, L. Joseph Melton, Claus Christiansen et al. · Journal of Bone and Mineral Research | Aug 1994 | 3,904 |
| 2 | Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis Steven Ron Cummings, Javier San Martín, Michael R. McClung et al. · New England Journal of Medicine | 11 Aug 2009 | 3,503 |
| 3 | Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes Struan F.A. Grant et al. · Nature Genetics | 15 Jan 2006 | 2,303 |
| 4 | Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection Robert E. Lanford, Elisabeth S. Hildebrandt-Eriksen, Andreas Petri et al. · Science | 3 Dec 2009 | 1,664 |
| 5 | Effects of Raloxifene on Bone Mineral Density, Serum Cholesterol Concentrations, and Uterine Endometrium in Postmenopausal Women Pierre Dominique Delmas, Nina H. Bjarnason, Bruce Mitlak et al. · New England Journal of Medicine | 4 Dec 1997 | 1,651 |
| 6 | Effects of Oral Ibandronate Administered Daily or Intermittently on Fracture Risk in Postmenopausal Osteoporosis Charles H. Chesnut, Arne Skag, Claus Christiansen et al. · Journal of Bone and Mineral Research | Aug 2004 | 1,232 |
| 7 | The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women John A. Kanis et al. · Osteoporosis International | 23 Feb 2007 | 1,228 |
| 8 | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture Karol Estrada et al. · Nature Genetics | 15 Apr 2012 | 1,223 |
| 9 | A variant in CDKAL1 influences insulin response and risk of type 2 diabetes Valgerður Steinthórsdóttir et al. · Nature Genetics | 26 Apr 2007 | 1,090 |
| 10 | Toward a new definition of mental health Silvana Galderisi, Andreas Heinz, Marianne Carisius Kastrup et al. · World Psychiatry | Jun 2015 | 959 |
| 11 | Shear Strength of Stud Connectors in Lightweight and Normal-Weight Concrete Jorgen G. Ollgaard, R. G. Slutter, John W. Fisher · Engineering Journal | 30 Jun 1971 | 874 |
| 12 | Effect of Abaloparatide vs Placebo on New Vertebral Fractures in Postmenopausal Women With Osteoporosis Paul D. Miller, Gary Hattersley, Bente Juel Riis et al. · JAMA | 16 Aug 2016 | 869 |
| 13 | Vertebral Fractures After Discontinuation of Denosumab: A Post Hoc Analysis of the Randomized Placebo-Controlled FREEDOM Trial and Its Extension Steven Ron Cummings, Serge Ferrari, Richard Eastell et al. · Journal of Bone and Mineral Research | 4 Nov 2017 | 732 |
| 14 | A 52-Week Placebo-Controlled Trial of Evolocumab in Hyperlipidemia Dirk Jacobus Blom, Tomas Hala, Michael A. Bolognese et al. · New England Journal of Medicine | 29 Mar 2014 | 730 |
| 15 | Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes Jūlı́us Guðmundsson et al. · Nature Genetics | Jul 2007 | 728 |
| 16 | The Collagenolytic Activity of Cathepsin K Is Unique among Mammalian Proteinases Patrick Garnero, Olivier Borel, I. Byrjalsen et al. · Journal of Biological Chemistry | Nov 1998 | 644 |
| 17 | Multiple Genetic Loci for Bone Mineral Density and Fractures Unnur Styrkársdóttir, Bjarni V. Halldórsson, Sólveig Grétarsdóttir et al. · New England Journal of Medicine | 29 Apr 2008 | 634 |
| 18 | Matrix Metalloproteinase 9 and Vascular Endothelial Growth Factor Are Essential for Osteoclast Recruitment into Developing Long Bones Michael T. Engsig, Qingjun Chen, Thiennu H. Vu et al. · The Journal of Cell Biology | 13 Nov 2000 | 599 |
| 19 | Incorporation and distribution of strontium in bone Svein G. Dahl, Philippe Allain, Pierre J. Marie et al. · Bone | Apr 2001 | 588 |
| 20 | Warfarin and Aspirin in Patients with Heart Failure and Sinus Rhythm Shunichi Homma et al. · New England Journal of Medicine | 2 May 2012 | 587 |
| 21 | Relationship Between Osteoporosis and Cardiovascular Disease in Postmenopausal Women László B. Tankó, Claus Christiansen, David Alan Cox et al. · Journal of Bone and Mineral Research | Nov 2005 | 548 |
| 22 | Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution Agnar Helgason et al. · Nature Genetics | 7 Jan 2007 | 530 |
| 23 | Effect of Evolocumab or Ezetimibe Added to Moderate- or High-Intensity Statin Therapy on LDL-C Lowering in Patients With Hypercholesterolemia Jennifer G. Robinson, Bettina S. Nedergaard, William John Rogers et al. · JAMA | 13 May 2014 | 507 |
| 24 | Efficacy of Bazedoxifene in Reducing New Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis: Results From a 3-Year, Randomized, Placebo-, and Active-Controlled Clinical Trial Stuart L. Silverman, Claus Christiansen, Harry K. Genant et al. · Journal of Bone and Mineral Research | 29 Jul 2008 | 507 |
| 25 | Prevention of Bone Loss with Alendronate in Postmenopausal Women under 60 Years of Age David J. Hosking, Clair E.D. Chilvers, Claus Christiansen et al. · New England Journal of Medicine | 19 Feb 1998 | 489 |
| 26 | A Meta-Analysis of the Association of Fracture Risk and Body Mass Index in Women Helena Johansson et al. · Journal of Bone and Mineral Research | 17 Jun 2013 | 482 |
| 27 | Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review Sergio Davinelli, Michael Engelbrecht Nielsen, Giovanni Scapagnini · Nutrients | 22 Apr 2018 | 471 |
| 28 | Low Body Mass Index Is an Important Risk Factor for Low Bone Mass and Increased Bone Loss in Early Postmenopausal Women Pernille Ravn, Giovanni Cizza, N. H. Bjarnason et al. · Journal of Bone and Mineral Research | Sep 1999 | 457 |
| 29 | The Effects of Tibolone in Older Postmenopausal Women Steven Ron Cummings, Bruce B. Ettinger, Pierre Dominique Delmas et al. · New England Journal of Medicine | 13 Aug 2008 | 456 |
| 30 | Anti-PCSK9 Monotherapy for Hypercholesterolemia Michael J. Koren, Pernille Lundqvist, Michael A. Bolognese et al. · Journal of the American College of Cardiology | 29 Mar 2014 | 415 |
| 31 | The Bone Lining Cell: Its Role in Cleaning Howship's Lacunae and Initiating Bone Formation Vincent E. Everts, Jean‐Marie Delaissé, Wolf Korper et al. · Journal of Bone and Mineral Research | 2002 | 409 |
| 32 | The association between low bone mass at the menopause and cardiovascular mortality Peter von der Recke, M.A. Hansen, Christian Hassager · The American Journal of Medicine | Mar 1999 | 404 |
| 33 | The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells Marina Simian, Yohei Hirai, Marc Navre et al. · Development | 15 Aug 2001 | 395 |
| 34 | Changes in Bone Mineral Density with Age in Men and Women: A Longitudinal Study Lise Warming, Christian Hassager, Claus Christiansen · Osteoporosis International | Feb 2002 | 388 |
| 35 | Generation and degradation of human endostatin proteins by various proteinases Mercedes Ferreras, Ute Felbor, Thomas Lenhard et al. · FEBS Letters | 12 Dec 2000 | 372 |
| 36 | New sequence variants associated with bone mineral density Unnur Styrkársdóttir, Bjarni V. Halldórsson, Sólveig Grétarsdóttir et al. · Nature Genetics | 14 Dec 2008 | 365 |
| 37 | Association between the Five Factor personality traits and perceived stress: is the effect mediated by general self-efficacy? Jeanette Frost Ebstrup, Lene Falgaard Eplov, Charlotta Holm Pisinger et al. · Anxiety Stress & Coping | 20 Nov 2010 | 363 |
| 38 | Circadian variation in the serum concentration of C-terminal telopeptide of type I collagen (serum CTx): effects of gender, age, menopausal status, posture, daylight, serum cortisol, and fasting Per Qvist, Stephan Christgau, B.J. Pedersen et al. · Bone | Jul 2002 | 356 |
| 39 | Matrix metalloproteinases (MMP) and cathepsin K contribute differently to osteoclastic activities Jean‐Marie Delaissé, Thomas Levin Andersen, Michael T. Engsig et al. · Microscopy Research and Technique | 18 Jul 2003 | 341 |
| 40 | Immunoassay for quantifying type I collagen degradation products in urine evaluated Martin Bonde, Per Qvist, Christian Fledelius et al. · Clinical Chemistry | Nov 1994 | 333 |
| 41 | Role of Gastrointestinal Hormones in Postprandial Reduction of Bone Resorption Dennis Bang Henriksen, Peter Alexandersen, Nina H. Bjarnason et al. · Journal of Bone and Mineral Research | Dec 2003 | 333 |
| 42 | Efficacy and tolerability of once-monthly oral ibandronate in postmenopausal osteoporosis: 2 year results from the MOBILE study Reginster Jy, S. Adámi, Peter Laszlo Lakatos et al. · Annals of the Rheumatic Diseases | 9 Dec 2005 | 328 |
| 43 | Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density Guðmar Þorleifsson et al. · Nature Genetics | 28 Jun 2009 | 324 |
| 44 | Serum CrossLaps One Step ELISA. First application of monoclonal antibodies for measurement in serum of bone-related degradation products from C-terminal telopeptides of type I collagen Christian Rosenquist, Christian Fledelius, Stephan Christgau et al. · Clinical Chemistry | Nov 1998 | 320 |
| 45 | Age- and menopause-associated variations in body composition and fat distribution in healthy women as measured by dual-energy x-ray absorptiometry Ole Lander Svendsen, Christian Hassager, Claus Christiansen · Metabolism | Mar 1995 | 306 |
| 46 | Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial Jean‐Yves Reginster, Janusz E. Badurski, Nicholas Bellamy et al. · Annals of the Rheumatic Diseases | Nov 2012 | 295 |
| 47 | Collagen type II C-telopeptide fragments as an index of cartilage degradation Stephan Christgau, Patrick Garnero, Christian Fledelius et al. · Bone | Sep 2001 | 289 |
| 48 | Low bone mass and fast rate of bone loss at menopause: Equal risk factors for future fracture: A 15-year follow-up Study B. Juel Riis, M.A. Hansen, Alexandria M. Jensen et al. · Bone | Jul 1996 | 282 |
| 49 | Daily and intermittent oral ibandronate normalize bone turnover and provide significant reduction in vertebral fracture risk: results from the BONE study For the Oral Ibandronate Osteoporosis Vertebral Fracture Trial in North America , Pierre Dominique Delmas, Robert R. Recker et al. · Osteoporosis International | 7 Apr 2004 | 280 |
| 50 | Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits Unnur Styrkársdóttir et al. · Nature | 3 May 2013 | 278 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.