Institution · Central Institute for Experimental Animals

Most cited papers from Central Institute for Experimental Animals

Central Institute for Experimental Animals

What are the most cited papers from Central Institute for Experimental Animals?

The most cited paper from Central Institute for Experimental Animals is "NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells" (Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi et al., 2002), with 1,487 citations. Next come "A defined commensal consortium elicits CD8 T cells and anti-cancer immunity" (1,147) and "Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis" (916).

Published TypeFieldAccessCitations

Showing 50 of 60 papers. Every paper with more than 168 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi et al. · Blood	16 Oct 2002	1,487
2	A defined commensal consortium elicits CD8 T cells and anti-cancer immunity Takeshi Tanoue et al. · Nature	23 Jan 2019	1,147
3	Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis Toshimasa Yamauchi et al. · Journal of Biological Chemistry Open access	2003	916
4	Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance Nozomu Kamei et al. · Journal of Biological Chemistry Open access	30 Jun 2006	914
5	New Neurons Follow the Flow of Cerebrospinal Fluid in the Adult Brain Kazunobu Sawamoto, Hynek Wichterle, Óscar González-Pérez et al. · Science	12 Jan 2006	803
6	Generation of transgenic non-human primates with germline transmission Erika Sasaki et al. · Nature	May 2009	741
7	Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians Yuko Sato et al. · Nature	29 Jul 2021	652
8	Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice Kazumasa Saigoh, Yulai Wang, Jun‐Gyo Suh et al. · Nature Genetics	Sep 1999	506
9	Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis Thorsten Boroviak, Remco Loos, Patrick Lombard et al. · Developmental Cell Open access	Nov 2015	487
10	Nongenetic method for purifying stem cell–derived cardiomyocytes Fumiyuki Hattori et al. · Nature Methods	29 Nov 2009	417
11	A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord Shinjiro Kaneko et al. · Nature Medicine	12 Nov 2006	412
12	Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q Naoki Miyoshi, Hirotaka Wagatsuma, Shigeharu Wakana et al. · Genes to Cells	Mar 2000	399
13	Transplantation of human neural stem cells for spinal cord injury in primates Akio Iwanami, Shinji Kaneko, Masaya Nakamura et al. · Journal of Neuroscience Research	2005	390
14	Extracellular nanovesicles for packaging of CRISPR-Cas9 protein and sgRNA to induce therapeutic exon skipping Peter Gee et al. · Nature Communications Open access	13 Mar 2020	381
15	Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier Jan Wijnholds, Elizabeth C. M. de Lange, George L. Scheffer et al. · Journal of Clinical Investigation Open access	Feb 2000	361
16	Current advances in humanized mouse models Ryoji Ito, Takeshi Takahashi, Ikumi Katano et al. · Cellular and Molecular Immunology Open access	13 Feb 2012	349
17	NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions Nobuko Futaki, Kensei Yoshikawa, Yumiko Hamasaka et al. · General Pharmacology The Vascular System	1993	347
18	Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo Katsuto Hozumi, Naoko Negishi, Daisuke Suzuki et al. · Nature Immunology	16 May 2004	340
19	PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice Taku Okazaki, Il‐mi Okazaki, Jian Wang et al. · The Journal of Experimental Medicine Open access	7 Feb 2011	334
20	Interleukin 12–dependent Interferon γ Production by CD8α+Lymphoid Dendritic Cells Toshiaki Ohteki, Taro Fukao, Kazutomo Suzue et al. · The Journal of Experimental Medicine Open access	21 Jun 1999	334
21	Skeletal muscle pathology in X chromosome-linked muscular dystrophy (mdx) mouse Yumi N. Tanabe, K. Esaki, Tatsuj Nomura · Acta Neuropathologica	1986	328
22	Pre-Evaluated Safe Human iPSC-Derived Neural Stem Cells Promote Functional Recovery after Spinal Cord Injury in Common Marmoset without Tumorigenicity Yoshiomi Kobayashi, Yohei Okada, Go Itakura et al. · PLoS ONE Open access	27 Dec 2012	328
23	Sexual orientation in Drosophila is altered by the satori mutation in the sex-determination gene fruitless that encodes a zinc finger protein with a BTB domain. Hiroki Ito, Kazuko Fujitani, Keisuke Usui et al. · Proceedings of the National Academy of Sciences Open access	3 Sep 1996	320
24	The reconstituted ‘humanized liver’ in TK-NOG mice is mature and functional Masami Hasegawa, Kenji Kawai, T Mitsui et al. · Biochemical and Biophysical Research Communications Open access	20 Jan 2011	320
25	Dectin-1 Contributes to Myocardial Ischemia/Reperfusion Injury by Regulating Macrophage Polarization and Neutrophil Infiltration Qin Fan, Rong Tao, Hang Zhang et al. · Circulation Open access	17 Jan 2019	306
26	Stem Cell-Like Properties of the Endometrial Side Population: Implication in Endometrial Regeneration Hirotaka Masuda, Yumi Matsuzaki, Emi Hiratsu et al. · PLoS ONE Open access	28 Apr 2010	304
27	Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells Takashi Yahata, Tomomi Takanashi, Yukari Muguruma et al. · Blood Open access	7 Jul 2011	302
28	Reconstitution of the functional human hematopoietic microenvironment derived from human mesenchymal stem cells in the murine bone marrow compartment Yukari Muguruma, Takashi Yahata, Hiroko Miyatake et al. · Blood	11 Nov 2005	294
29	Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor Takahiro Ueda, Kohichiro Tsuji, Hiroshi Yoshino et al. · Journal of Clinical Investigation Open access	Apr 2000	284
30	Albumin-Deficient Rat Mutant Sumi Nagase, Kane Shimamune, Seigo Shumiya · Science	10 Aug 1979	279
31	Quantitative Atlas of Blood–Brain Barrier Transporters, Receptors, and Tight Junction Proteins in Rats and Common Marmoset Yutaro Hoshi, Yasuo Uchida, Masanori Tachikawa et al. · Journal of Pharmaceutical Sciences	6 May 2013	258
32	Peg3 imprinted gene on proximal chromosome 7 encodes for a zinc finger protein Yoshimi Kuroiwa, Tomoko Kaneko‐Ishino, F Kagitani et al. · Nature Genetics	Feb 1996	258
33	Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/γcnull mice model Hidefumi Hiramatsu, Ryuta Nishikomori, Toshio Heike et al. · Blood Open access	15 Apr 2003	252
34	Human hepatic organoids for the analysis of human genetic diseases Yuan Guan, Dan Xu, Phillip M. Garfin et al. · JCI Insight Open access	6 Sep 2017	244
35	Visualization of peripheral nerve degeneration and regeneration: Monitoring with diffusion tensor tractography Takehiko Takagi, Masaya Nakamura, Masayuki Yamada et al. · NeuroImage	3 Oct 2008	244
36	Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis Joanes Grandjean et al. · NeuroImage Open access	12 Oct 2019	243
37	Brain/MINDS: A Japanese National Brain Project for Marmoset Neuroscience Hideyuki Okano, Erika Sasaki, Tetsuo Yamamori et al. · Neuron Open access	Nov 2016	236
38	Common marmoset as a new model animal for neuroscience research and genome editing technology Noriyuki Kishi, Kenya Sato, Erika Sasaki et al. · Development Growth & Differentiation	2014	234
39	Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development Thorsten Boroviak, Giuliano Giuseppe Stirparo, Sabine Dietmann et al. · Development Open access	Nov 2018	232
40	Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies Paras Singh Minhas et al. · Science Open access	22 Aug 2024	231
41	Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity Yuki Kagoya, Akihide Yoshimi, Keisuke Kataoka et al. · Journal of Clinical Investigation Open access	2014	229
42	The common marmoset as a novel animal model system for biomedical and neuroscience research applications Hideyuki Okano, Keigo Hikishima, Atsushi Iriki et al. · Seminars in Fetal and Neonatal Medicine	4 Aug 2012	228
43	The analysis of the functions of human B and T cells in humanized NOD/shi-scid/γcnull (NOG) mice (hu-HSC NOG mice) Y. Watanabe, Takeshi Takahashi, Akira Okajima et al. · International Immunology Open access	10 Jun 2009	225
44	Cloned Mice from Fetal Fibroblast Cells Arrested at Metaphase by a Serial Nuclear Transfer1 Yukiko Ono, Nobuhiro Shimozawa, Mamoru Ito et al. · Biology of Reproduction	2001	225
45	Abundant Occurrence of Basal Radial Glia in the Subventricular Zone of Embryonic Neocortex of a Lissencephalic Primate, the Common Marmoset Callithrix jacchus Iva Kelava, Isabel Reillo, Ayako Y. Murayama et al. · Cerebral Cortex Open access	23 Nov 2011	214
46	Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells Bo Wang, Shoichi Iriguchi, Masazumi Waseda et al. · Nature Biomedical Engineering	17 May 2021	204
47	Side population in human uterine myometrium displays phenotypic and functional characteristics of myometrial stem cells Masanori Ono, Tetsuo Maruyama, Hirotaka Masuda et al. · Proceedings of the National Academy of Sciences Open access	14 Nov 2007	203
48	Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production Yuta Myojin, Hayato Hikita, Masaya Sugiyama et al. · Gastroenterology Open access	17 Dec 2020	202
49	Hematopoietic stem cell–engrafted NOD/SCID/IL2Rγnull mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses Satoru Watanabe, Kazuo Terashima, Shinrai Ohta et al. · Blood Open access	5 Sep 2006	202
50	Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset Michael Heide, Christiane Haffner, Ayako Y. Murayama et al. · Science	18 Jun 2020	194

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.