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Research facility · Kawasaki · Japan

Central Institute for Experimental Animals

In research, Central Institute for Experimental Animals stands highest in Life Sciences (#3,990 of 11,023 worldwide), Biochemistry, Genetics and Molecular Biology (#2,924 of 5,801 worldwide) and Medicine (#7,665 of 14,558 worldwide), over all time.

ciea.or.jp/enROR OpenAlex
World rank, 2022-now
#21,781
of 22,385 · #16,953 all time
Rank in Japan
#836
of 924
Research works
775
▼ 33% vs 2018-21
Citations
17k
21.9 per fractional work
Top-10% rate
6.6%
all institutions 10.0%
vs its own fields
0.96×
1.00× is exactly expected
Open access
54%
world 40%
International
14%
world 18%
Central Institute for Experimental Animals

What is Central Institute for Experimental Animals known for in research?

The fields where it stands highest, over all time, ranked among every institution above the floor in each field.

FieldWorld rankWhere that sitsTop-10% rateWorks
Life SciencesDomain #3,990 of 11,023 5.2%425
Biochemistry, Genetics and Molecular BiologyField #2,924 of 5,801 5.8%226
MedicineField #7,665 of 14,558 6.1%269
Health SciencesDomain #9,026 of 16,688 5.8%290
Molecular BiologySubfield #2,324 of 3,729 5.8%123

Each strip is that field's whole ranked pool, with the notch where Central Institute for Experimental Animals sits in it, in the colour of the band that rank falls in. The track under the rate is the rate itself: it carries no average mark, because the average differs by field (from about 6% in Dentistry to 21% in Economics).

Which fields of science does Central Institute for Experimental Animals work in?

In 2022-now, 55% of research at Central Institute for Experimental Animals is in Life Sciences, 35% in Health Sciences. Its largest fields are Medicine (33%), Biochemistry, Genetics and Molecular Biology (31%), Immunology and Microbiology (9%). It does 3.4× the world's share of Life Sciences.

Life Sciences: 38 fractional works · 55.1% of its workBiochemistry, Genetics and Molecular Biology: 21 fractional works · 30.7% of its workMolecular Biology: 12 fractional works · 18.0% of its workCell Biology: 2 fractional works · 2.5% of its workBiochemistry: 2 fractional works · 2.5% of its workCancer Research: 2 fractional works · 2.4% of its workGenetics: 2 fractional works · 2.2% of its workBiotechnology: 1 fractional works · 1.4% of its workClinical Biochemistry: 1 fractional works · 1.0% of its workBiophysics: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.5% of its workImmunology and Microbiology: 6 fractional works · 8.5% of its workImmunology: 6 fractional works · 8.0% of its workMicrobiology: 0 fractional works · 0.5% of its workSmaller subfields together: 0 fractional works · 0.1% of its workPharmacology, Toxicology and Pharmaceutics: 5 fractional works · 7.5% of its workPharmacology: 5 fractional works · 6.5% of its workPharmaceutical Science: 1 fractional works · 0.9% of its workSmaller subfields together: 0 fractional works · 0.2% of its workNeuroscience: 5 fractional works · 6.8% of its workCognitive Neuroscience: 1 fractional works · 2.1% of its workCellular and Molecular Neuroscience: 1 fractional works · 2.0% of its workDevelopmental Neuroscience: 1 fractional works · 0.8% of its workNeurology: 1 fractional works · 0.8% of its workSensory Systems: 0 fractional works · 0.4% of its workBiological Psychiatry: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.3% of its workAgricultural and Biological Sciences: 1 fractional works · 1.6% of its workEcology, Evolution, Behavior and Systematics: 1 fractional works · 0.9% of its workInsect Science: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.4% of its workHealth Sciences: 24 fractional works · 35.0% of its workMedicine: 23 fractional works · 33.3% of its workOncology: 4 fractional works · 5.0% of its workPhysiology: 3 fractional works · 3.7% of its workHematology: 2 fractional works · 3.1% of its workSurgery: 2 fractional works · 2.4% of its workRadiology, Nuclear Medicine and Imaging: 2 fractional works · 2.4% of its workPulmonary and Respiratory Medicine: 2 fractional works · 2.3% of its workPharmacology: 1 fractional works · 2.0% of its workHepatology: 1 fractional works · 1.9% of its workPublic Health, Environmental and Occupational Health: 1 fractional works · 1.4% of its workEpidemiology: 1 fractional works · 1.1% of its workPediatrics, Perinatology and Child Health: 1 fractional works · 1.1% of its workGenetics: 1 fractional works · 1.0% of its workRheumatology: 1 fractional works · 0.9% of its workEndocrinology, Diabetes and Metabolism: 1 fractional works · 0.7% of its workCardiology and Cardiovascular Medicine: 0 fractional works · 0.7% of its workPathology and Forensic Medicine: 0 fractional works · 0.7% of its workPsychiatry and Mental health: 0 fractional works · 0.6% of its workReproductive Medicine: 0 fractional works · 0.6% of its workUrology: 0 fractional works · 0.3% of its workAnesthesiology and Pain Medicine: 0 fractional works · 0.2% of its workNeurology: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.7% of its workVeterinary: 1 fractional works · 1.4% of its workSmall Animals: 1 fractional works · 1.4% of its workNursing: 0 fractional works · 0.3% of its workNutrition and Dietetics: 0 fractional works · 0.3% of its workHealth Professions: 0 fractional works · 0.0% of its workPhysical Sciences: 5 fractional works · 7.7% of its workEngineering: 2 fractional works · 3.3% of its workBiomedical Engineering: 2 fractional works · 3.0% of its workAerospace Engineering: 0 fractional works · 0.3% of its workEnvironmental Science: 1 fractional works · 1.5% of its workHealth, Toxicology and Mutagenesis: 1 fractional works · 1.0% of its workEcology: 0 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.1% of its workComputer Science: 1 fractional works · 0.9% of its workComputational Theory and Mathematics: 1 fractional works · 0.8% of its workSmaller subfields together: 0 fractional works · 0.2% of its workChemistry: 1 fractional works · 0.8% of its workOrganic Chemistry: 0 fractional works · 0.6% of its workSmaller subfields together: 0 fractional works · 0.2% of its workEarth and Planetary Sciences: 0 fractional works · 0.4% of its workPaleontology: 0 fractional works · 0.4% of its workMathematics: 0 fractional works · 0.2% of its workStatistics and Probability: 0 fractional works · 0.2% of its workPhysics and Astronomy: 0 fractional works · 0.2% of its workEnergy: 0 fractional works · 0.2% of its workMaterials Science: 0 fractional works · 0.1% of its workSocial Sciences: 2 fractional works · 2.2% of its workPsychology: 2 fractional works · 2.2% of its workSocial Psychology: 2 fractional works · 2.2% of its workBusiness, Management and Accounting: 0 fractional works · 0.1% of its workALL ITS WORKCentral Institutefor Experimental…70fractional works, 2022-now
Life Sciences55%Physical Sciences8%Health Sciences35%Social Sciences2%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in 2022-now. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 20 fields, with their numbers
    1. Biochemistry, Genetics and Molecular Biology2130.7%
    2. Immunology and Microbiology68.5%
    3. Pharmacology, Toxicology and Pharmaceutics57.5%
    4. Neuroscience56.8%
    5. Agricultural and Biological Sciences11.6%
    1. Medicine2333.3%
    2. Veterinary11.4%
    3. Nursing00.3%
    4. Health Professions00.0%
    1. Engineering23.3%
    2. Environmental Science11.5%
    3. Computer Science10.9%
    4. Chemistry10.8%
    5. Earth and Planetary Sciences00.4%
    6. Mathematics00.2%
    7. Physics and Astronomy00.2%
    8. Energy00.2%
    9. Materials Science00.1%
    1. Psychology22.2%
    2. Business, Management and Accounting00.1%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 0.33× its world share, 1 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 5.76× its world share, 21 worksBiochemistry, Geneti…Immunology and Microbiology: 8.48× its world share, 6 worksImmunology and Micro…Neuroscience: 4.17× its world share, 5 worksNeurosciencePharmacology, Toxicology and Pharmaceutics: 21.37× its world share, 5 worksPharmacology, Toxico…Chemistry: 0.51× its world share, 1 worksChemistryComputer Science: 0.12× its world share, 1 worksComputer ScienceEarth and Planetary Sciences: 0.24× its world share, 0 worksEarth and Planetary …Energy: 0.17× its world share, 0 worksEnergyEngineering: 0.22× its world share, 2 worksEngineeringEnvironmental Science: 0.31× its world share, 1 worksEnvironmental ScienceMaterials Science: 0.03× its world share, 0 worksMaterials ScienceMathematics: 0.20× its world share, 0 worksMathematicsPhysics and Astronomy: 0.09× its world share, 0 worksPhysics and AstronomyHealth Professions: 0.01× its world share, 0 worksHealth ProfessionsMedicine: 1.73× its world share, 23 worksMedicineNursing: 0.68× its world share, 0 worksNursingVeterinary: 9.99× its world share, 1 worksVeterinaryBusiness, Management and Accounting: 0.02× its world share, 0 worksBusiness, Management…Psychology: 0.71× its world share, 2 worksPsychology1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Pharmacology, Toxicology and Pharmaceutics, 21.4×. Every wedge is a field page.

All 20 fields, with their numbers
  1. Pharmacology, Toxicology and Pharmaceutics21.37×5 works
  2. Veterinary9.99×1 works
  3. Immunology and Microbiology8.48×6 works
  4. Biochemistry, Genetics and Molecular Biology5.76×21 works
  5. Neuroscience4.17×5 works
  6. Medicine1.73×23 works
  7. Psychology0.71×2 works
  8. Nursing0.68×0 works
  9. Chemistry0.51×1 works
  10. Agricultural and Biological Sciences0.33×1 works
  11. Environmental Science0.31×1 works
  12. Earth and Planetary Sciences0.24×0 works
  13. Engineering0.22×2 works
  14. Mathematics0.20×0 works
  15. Energy0.17×0 works
  16. Computer Science0.12×1 works
  17. Physics and Astronomy0.09×0 works
  18. Materials Science0.03×0 works
  19. Business, Management and Accounting0.02×0 works
  20. Health Professions0.01×0 works

Who are the top researchers at Central Institute for Experimental Animals?

Ranked on the quality score, Mamoru Ito, Ikumi Katano and Kimio Kobayashi lead among researchers whose main affiliation is Central Institute for Experimental Animals.

  1. 1 Mamoru Ito Japan · #785,242 worldwide 14k citations · 328 works
  2. 2 Ikumi Katano Japan · #873,642 worldwide 2.2k citations · 75 works
  3. 3 Kimio Kobayashi Japan · #1,041,854 worldwide 4.4k citations · 70 works
  4. 4 Motohito Goto Japan · #1,309,729 worldwide 1.8k citations · 67 works
  5. 5 Yoko Kurotaki Japan · #1,444,700 worldwide 2.1k citations · 28 works
  6. 6 Ryoji Ito Japan · #1,543,639 worldwide 4.3k citations · 212 works
  7. 7 Junko Okahara Japan · #1,593,496 worldwide 1.1k citations · 35 works
  8. 8 Erika Sasaki Japan · #1,660,737 worldwide 7.3k citations · 266 works
  9. 9 Masafumi Yamamoto Japan · #1,993,983 worldwide 2.3k citations · 80 works
  10. 10 Tomoo Eto Japan · #2,235,555 worldwide 2k citations · 40 works
All ranked researchers at Central Institute for Experimental Animals

What are the most cited papers from Central Institute for Experimental Animals?

The most cited paper from Central Institute for Experimental Animals is "NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells" (Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi et al., 2002), with 1,487 citations. Next come "A defined commensal consortium elicits CD8 T cells and anti-cancer immunity" (1,147) and "Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis" (916).

Most cited papers
#PaperReleasedCitations
1 NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi et al. · Blood 16 Oct 2002 1,487
2 A defined commensal consortium elicits CD8 T cells and anti-cancer immunity Takeshi Tanoue et al. · Nature 23 Jan 2019 1,147
3 Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis Toshimasa Yamauchi et al. · Journal of Biological Chemistry Open access 2003 916
4 Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance Nozomu Kamei et al. · Journal of Biological Chemistry Open access 30 Jun 2006 914
5 New Neurons Follow the Flow of Cerebrospinal Fluid in the Adult Brain Kazunobu Sawamoto, Hynek Wichterle, Óscar González-Pérez et al. · Science 12 Jan 2006 803
All 60 most cited papers, with filters and sorting

Which keywords describe research at Central Institute for Experimental Animals?

By fractional works in 2022-now, weighted toward what it does more of than the world: Inflammation, Oxidative Stress, Pharmacokinetics, Cytochrome P450, Genetic Variation, Drug Metabolism, Pharmacogenetics and Cancer.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in 2022-now in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Inflammation8▲ 5.2×31 topics
  2. Oxidative Stress6▲ 5.2×26 topics
  3. Pharmacokinetics5▲ 25×4 topics
  4. Cytochrome P4504▲ 189×2 topics
  5. Cancer4▲ 3.9×20 topics
  6. Genetic Variation4▲ 23×3 topics
  7. Drug Metabolism3▲ 176×1 topic
  8. Pharmacogenetics3▲ 238×1 topic
  9. Immunotherapy3▲ 5.5×7 topics
  10. Nuclear Receptors2▲ 40×5 topics
  11. Metabolism2▲ 6.2×7 topics
  12. Metabolic Regulation2▲ 19×4 topics
  13. Drug Discovery2▲ 13×5 topics
  14. Biomarkers2▲ 4.2×7 topics
  15. Gene Therapy2▲ 15×5 topics
  16. Transcriptional Regulation2▲ 17×7 topics
  17. Reactive Oxygen Species2▲ 6.7×8 topics
  18. Tumor Targeting2▲ 15×2 topics
  19. Evolution2▲ 9.5×3 topics
  20. Gene Expression2▲ 4.0×8 topics
  21. ATP-dependent Transporters2▲ 101×1 topic
  22. Brain Development2▲ 14×6 topics
  23. Mitochondrial Dysfunction2▲ 8.2×4 topics
  24. Multidrug Resistance2▲ 74×1 topic
  25. Neurological Disorders2▲ 4.3×7 topics
  26. Immunity2▲ 5.8×4 topics
  27. TGF-ß2▲ 14×3 topics
  28. Hypertension2▲ 7.2×5 topics
  29. Innate Immunity2▲ 6.5×5 topics
  30. NK Cell Recognition2▲ 34×1 topic
  31. Natural Killer Cells2▲ 34×1 topic
  32. Social Behavior2▲ 37×2 topics
  33. Toxicology2▲ 13×4 topics
  34. Intelligence1▲ 50×1 topic
  35. Primates1▲ 107×1 topic
  36. Autoimmunity1▲ 13×3 topics
  37. Cardiovascular Function1▲ 52×2 topics
  38. Differentiation1▲ 30×2 topics
  39. Liver Transplantation1▲ 16×3 topics
  40. Tumor Regression1▲ 17×2 topics

Which research topics does Central Institute for Experimental Animals publish most on?

By volume in 2022-now: Pharmacogenetics and Drug Metabolism, Drug Transport and Resistance Mechanisms, Immune Cell Function and Interaction and Primate Behavior and Ecology.

Pharmacogenetics and Dru…3Pharmacogenetics and Drug Metabolism: 3 fractional worksDrug Transport and Resistance Mechanisms: 2 fractional worksImmune Cell Function and Interaction: 2 fractional worksPrimate Behavior and Ecology: 1 fractional worksDrug-Induced Hepatotoxicity and Protection: 1 fractional worksLiver physiology and pathology: 1 fractional worksCRISPR and Genetic Engin…1CRISPR and Genetic Engineering: 1 fractional worksCancer Research and Treatments: 1 fractional worksEicosanoids and Hypertension Pharmacology: 1 fractional worksT-cell and B-cell Immuno…1T-cell and B-cell Immunology: 1 fractional works
PharmacologyOncologyImmunologySocial Psychology4 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 Pharmacogenetics and Drug Metabolism Pharmacology 3 works
  2. 2 Drug Transport and Resistance Mechanisms Oncology 2 works
  3. 3 Immune Cell Function and Interaction Immunology 2 works
  4. 4 Primate Behavior and Ecology Social Psychology 1 works
  5. 5 Drug-Induced Hepatotoxicity and Protection Pharmacology 1 works
  6. 6 Liver physiology and pathology Hepatology 1 works
  7. 7 CRISPR and Genetic Engineering Molecular Biology 1 works
  8. 8 Cancer Research and Treatments Biotechnology 1 works
  9. 9 Eicosanoids and Hypertension Pharmacology Biochemistry 1 works
  10. 10 T-cell and B-cell Immunology Immunology 1 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available54.1%not open45.9%

World: 40% of research is openly available.

with international co-authors13.8%domestic only86.2%

World: 18% is written across borders.

How has Central Institute for Experimental Animals's research output changed?

Output in 2022-2025 was 33% lower than in 2018-2021.

still counting1990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Central Institute for Experimental Animals as a percentage of every work published that year, 0.00025% in 2024.

still counting0.0025%0.0050%0.0075%Central Institute for Experimental Animals0.00034% in 202519801990200020102020

Fractional works of Central Institute for Experimental Animals over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year, against all institutions in the same year.

still counting5%10%15%all institutions10.0% in 2025Central Institute for Experimental Animals3.7% in 202520102020

Of each year's output, the share that reached the world's 10% most cited for its field and year. Peak 11.0% in 2020.

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