Drug-Induced Hepatotoxicity and Protection
Drug-Induced Hepatotoxicity and Protection is a research topic within Pharmacology. Science Explorer counts 36k research works in it since 1950. 18.6% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the mechanisms, risk factors, biomarkers, and management of drug-induced hepatotoxicity, with a specific emphasis on acetaminophen-induced liver injury. It covers topics such as oxidative stress, mitochondrial dysfunction, HLA genotype associations, idiosyncratic reactions, and the role of liver transplantation in severe cases.
- Hepatotoxicity
- Drug-Induced Liver Injury
- Acetaminophen
- Oxidative Stress
- Mitochondrial Dysfunction
- Antioxidants
- HLA Genotype
- Idiosyncratic Reactions
- Biomarkers
- Liver Transplantation
- Research works
- 36k fractional, since 1950
- In the world top 10%
- 6.6k per year above
- Top-10% rate
- 18.6% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +35% the tick is no change
Which countries lead Drug-Induced Hepatotoxicity and Protection research?
By volume, India and China publish the most (1.1k and 1k works in 2022–2025).
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Drug-Induced Hepatotoxicity and Protection research?
By volume in 2022–2025, Desh Bhagat Ayurvedic College and Hospital publishes the most Drug-Induced Hepatotoxicity and Protection research, followed by Cairo University and Vaidyaratnam P.S. Varier Ayurveda College.
By volume, 2022–2025
- 1 Desh Bhagat Ayurvedic College and Hospital India 36 works
- 2 Cairo University Egypt 28 works
- 3 Vaidyaratnam P.S. Varier Ayurveda College India 27 works
- 4 National Institute of Ayurveda India 26 works
- 5 Government Ayurved College, Nanded India 26 works
- 6 King Saud University Saudi Arabia 25 works
- 7 Government Ayurvedic College and Hospital India 25 works
- 8 Mansoura University Egypt 22 works
- 9 Ain Shams University Egypt 20 works
- 10 National Research Centre Egypt 18 works
Who are the leading researchers in Drug-Induced Hepatotoxicity and Protection?
The most-cited researchers publishing on Drug-Induced Hepatotoxicity and Protection include Alberto Ortíz, Félix Carvalho and Paul I. Dargan.
- 1 Alberto Ortíz 5.9k citations
- 2 Félix Carvalho 4.6k citations
- 3 Paul I. Dargan 4.2k citations
- 4 Kunio Yagi 4k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Drug-Induced Hepatotoxicity and Protection research done?
The largest centres of Drug-Induced Hepatotoxicity and Protection research in 2022–2025 are Beijing (China), New Delhi (India), Shanghai (China) and Cairo (Egypt). Among places with at least 20 works in it, it is an unusually large share of all research in Amloh, Malappuram and Nanded.
Largest cities, 2022–2025
Where it is the local speciality
- AmlohIN · 36.4 works77×
- MalappuramIN · 29.6 works37×
- NandedIN · 28.0 works37×
- Port HarcourtNG · 30.5 works14×
Location quotient: how much more of its research is in Drug-Induced Hepatotoxicity and Protection than the world average.
Where is the best place to study Drug-Induced Hepatotoxicity and Protection?
Among universities, judged by research, Chengdu University of Traditional Chinese Medicine, Mansoura University and Tanta University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Chengdu University of Traditional Chinese Medicine China | 77.1 | 45.1% | 12.5× | 16 | +152.3% |
| 2 | Mansoura University Egypt | 72.1 | 24.9% | 8.6× | 22 | +254.5% |
| 3 | Tanta University Egypt | 65.2 | 21.8% | 8.8× | 16 | +282.7% |
| 4 | Al-Azhar University Egypt | 65.1 | 26.1% | 7.1× | 16 | +218.9% |
| 5 | Minia University Egypt | 63.9 | 26.4% | 9.8× | 11 | +166.9% |
| 6 | Beni-Suef University Egypt | 61.7 | 28.4% | 10.8× | 10 | +89.1% |
| 7 | Cairo University Egypt | 60.3 | 20.7% | 6.3× | 28 | +118.5% |
| 8 | Shanghai University of Traditional Chinese Medicine China | 58.1 | 29.9% | 14.2× | 16 | -2.1% |
| 9 | Zagazig University Egypt | 57.7 | 16.6% | 7.2× | 16 | +300.4% |
| 10 | King Saud University Saudi Arabia | 57.3 | 22.0% | 4.8× | 26 | +51.1% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Drug-Induced Hepatotoxicity and Protection research growing?
Output in 2018–2022 was 35% higher than in 2013–2017, peaking in 2022. The fastest-growing topics are Drug-Induced Hepatotoxicity and Protection.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.