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Topic · Developmental Neuroscience

Neurogenesis and neuroplasticity mechanisms

Neurogenesis and neuroplasticity mechanisms is a research topic within Developmental Neuroscience. Science Explorer counts 38k research works in it since 1950. 9.8% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the phenomenon of adult neurogenesis, focusing on the generation, differentiation, and functional implications of new neurons and glial cells in the mammalian brain. It covers various aspects such as the role of neurogenesis in brain development, neuronal replacement, synaptic plasticity, cognitive function, and the potential therapeutic applications for neurological disorders.

  • Neurogenesis
  • Adult Stem Cells
  • Brain Development
  • Neuronal Differentiation
  • Hippocampal Neurogenesis
  • Oligodendrocyte Progenitors
  • Neural Stem Cells
  • Glia and Neurons
  • Cortical Development
  • Neurogenic Niches
Research works
38k
fractional, since 1950
In the world top 10%
3.7k
per year above
Top-10% rate
9.8%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-2%
the tick is no change
Largest producer
United States
33% of the 10 largest, 2022-now
Neurogenesis and neuroplasticity mechanisms

Which countries lead Neurogenesis and neuroplasticity mechanisms research?

By volume, the United States and China publish the most (1.4k and 1.2k works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.4k works
  2. 2 China 1.2k works
  3. 3 Japan 339 works
  4. 4 Germany 287 works
  5. 5 Canada 199 works
  6. 6 United Kingdom 199 works
  7. 7 Italy 174 works
  8. 8 France 172 works
  9. 9 Spain 164 works
  10. 10 South Korea 146 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 33.3%China: 28.1%Japan: 7.8%Germany: 6.6%6 others listed: 24.3%33%largest
United States1,446 · 33.3%China1,220 · 28.1%Japan339 · 7.8%Germany287 · 6.6%6 others listed1,055 · 24.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead Neurogenesis and neuroplasticity mechanisms research?

By volume in 2022-now, Harvard University publishes the most Neurogenesis and neuroplasticity mechanisms research, followed by Russian Academy of Sciences and Centre National de la Recherche Scientifique.

By volume, 2022-now

  1. 1 Harvard UniversityUnited States 58 works
  2. 2 Russian Academy of SciencesRussia 55 works
  3. 3 Centre National de la Recherche ScientifiqueFrance 49 works
  4. 4 Chinese Academy of SciencesChina 42 works
  5. 5 InsermFrance 41 works
  6. 6 University of TorontoCanada 39 works
  7. 7 Fudan UniversityChina 36 works
  8. 8 Johns Hopkins UniversityUnited States 35 works
  9. 9 Sun Yat-sen UniversityChina 32 works
  10. 10 Shanghai Jiao Tong UniversityChina 31 works

Who are the leading researchers in Neurogenesis and neuroplasticity mechanisms?

The most-cited researchers publishing on Neurogenesis and neuroplasticity mechanisms include Shizuo Akira, Jun Wang and Matthias Mann.

  1. 1 Shizuo Akira Japan 342k citations
  2. 2 Jun Wang China 340k citations
  3. 3 Matthias Mann Germany 308k citations
  4. 4 Dan J. Stein South Africa 306k citations
  5. 5 Róbert Langer United States 303k citations
  6. 6 John Q. Trojanowski United States 286k citations
  7. 7 Luigi Ferrucci United States 281k citations
  8. 8 Hans C. Clevers Netherlands 260k citations
  9. 9 Amirhossein Sahebkar Iran 258k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Neurogenesis and neuroplasticity mechanisms?

The most cited paper in Neurogenesis and neuroplasticity mechanisms is "Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy" (Shikshya Shrestha, Steven M. Offer, 2016), with 8,958 citations. Next come "Neurogenesis in the adult human hippocampus" (6,370) and "Cerebral organoids model human brain development and microcephaly" (5,545).

Most cited papers
#PaperReleasedCitations
1 Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy Shikshya Shrestha, Steven M. Offer · Medical Epigenetics Open access 23 Mar 2016 8,958
2 Neurogenesis in the adult human hippocampus Peter S. Eriksson, Ekaterina Perfilieva, Thomas Björk‐Eriksson et al. · Nature Medicine Nov 1998 6,370
3 Cerebral organoids model human brain development and microcephaly Madeline A. Lancaster, Magdalena Renner, Carol-Anne Martin et al. · Nature Open access 27 Aug 2013 5,545
4 Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System Brent A. Reynolds, Samuel A. Weiss · Science 27 Mar 1992 5,431
5 Astrocytes: biology and pathology Michael V. Sofroniew, Harry V. Vinters · Acta Neuropathologica Open access 9 Dec 2009 5,277
All 100 most cited papers, with filters and sorting

Where is Neurogenesis and neuroplasticity mechanisms research done?

The largest centres of Neurogenesis and neuroplasticity mechanisms research in 2022-now are Beijing (China), Shanghai (China), Paris (France) and Guangzhou (China). Among places with at least 20 works in it, it is an unusually large share of all research in Nantong.

Largest cities, 2022-now

  1. 1 BeijingChina 164 works
  2. 2 ShanghaiChina 119 works
  3. 3 ParisFrance 96 works
  4. 4 GuangzhouChina 93 works
  5. 5 TokyoJapan 90 works
  6. 6 LondonUnited Kingdom 72 works
  7. 7 New YorkUnited States 68 works
  8. 8 SeoulSouth Korea 62 works
  9. 9 MoscowRussia 60 works
  10. 10 MadridSpain 52 works

Where it is the local speciality

  1. NantongCN · 27.7 works11×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Neurogenesis and neuroplasticity mechanisms than the world average.

See Neurogenesis and neuroplasticity mechanisms on the map

Where is the best place to study Neurogenesis and neuroplasticity mechanisms?

Among universities, judged by research, Harvard University, Stanford University and Johns Hopkins University score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 14.7%fractional works in this field (log) →share of work in the world top 10% →Stanford UniversityHarvard UniversityJohns Hopkins Univer…University of Toronto
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 75.018.0%3.7×58 -14.4%
2Stanford UniversityUnited States 68.920.7%3.7×27 -15.5%
3Johns Hopkins UniversityUnited States 64.514.7%4.7×35 -2.1%
4University of TorontoCanada 61.210.0%3.9×39 +6.5%
5McGill UniversityCanada 61.211.6%6.2×30 +11.4%
6University of California, San FranciscoUnited States 59.814.9%6.5×23 -20.3%
7Washington University in St. LouisUnited States 59.811.8%6.2×22 +48.9%
8Nantong UniversityChina 59.621.0%12.7×28 +0.5%
9University of California San DiegoUnited States 58.111.1%4.7×23 +20.0%
10Fudan UniversityChina 58.013.2%4.7×36 +36.9%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Neurogenesis and neuroplasticity mechanisms, country by country

Is Neurogenesis and neuroplasticity mechanisms research growing?

Output in 2022-2025 was 2% lower than in 2018-2021, peaking in 2025.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Neurogenesis and neuroplasticity mechanisms as a percentage of every work published that year, 0.019% in 2024.

still counting0.020%0.040%0.060%Neurogenesis and neuroplasticity mechanisms0.024% in 202519801990200020102020

Fractional works of Neurogenesis and neuroplasticity mechanisms over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Neurogenesis and neuroplasticity mechanisms9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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