Most cited papers in Neurogenesis and neuroplasticity mechanisms
What are the most cited papers in Neurogenesis and neuroplasticity mechanisms?
The most cited paper in Neurogenesis and neuroplasticity mechanisms is "Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy" (Shikshya Shrestha, Steven M. Offer, 2016), with 8,958 citations. Next come "Neurogenesis in the adult human hippocampus" (6,370) and "Cerebral organoids model human brain development and microcephaly" (5,545).
Showing 50 of 100 papers. Every paper with more than 1,771 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy Shikshya Shrestha, Steven M. Offer · Medical Epigenetics | 23 Mar 2016 | 8,958 |
| 2 | Neurogenesis in the adult human hippocampus Peter S. Eriksson, Ekaterina Perfilieva, Thomas Björk‐Eriksson et al. · Nature Medicine | Nov 1998 | 6,370 |
| 3 | Cerebral organoids model human brain development and microcephaly Madeline A. Lancaster, Magdalena Renner, Carol-Anne Martin et al. · Nature | 27 Aug 2013 | 5,545 |
| 4 | Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System Brent A. Reynolds, Samuel A. Weiss · Science | 27 Mar 1992 | 5,431 |
| 5 | Astrocytes: biology and pathology Michael V. Sofroniew, Harry V. Vinters · Acta Neuropathologica | 9 Dec 2009 | 5,277 |
| 6 | Identification of a cancer stem cell in human brain tumors. Sheila Kumari Singh, Ian D. Clarke, Mizuhiko Terasaki et al. · PubMed | 15 Sep 2003 | 4,896 |
| 7 | Exercise training increases size of hippocampus and improves memory Kirk I. Erickson, Michelle W. Voss, Ruchika Shaurya Prakash et al. · Proceedings of the National Academy of Sciences | 31 Jan 2011 | 4,886 |
| 8 | Mammalian Neural Stem Cells Fred H. Gage · Science | 25 Feb 2000 | 4,770 |
| 9 | Neurotrophins: Roles in Neuronal Development and Function Eric Jinsheng Huang, Louis French Reichardt · Annual Review of Neuroscience | Mar 2001 | 4,433 |
| 10 | Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants Luca Santarelli, Michael Saxe, Cornelius Thilo Gross et al. · Science | 8 Aug 2003 | 4,334 |
| 11 | Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd et al. · Neuron | Jul 2003 | 4,207 |
| 12 | Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice Anna Claudia Domingos da Silveira da Luz, Gisele Pereira Dias, Mário Cesar do Nascimento Bevilaqua et al. · Neuropsychobiology | 2013 | 4,008 |
| 13 | Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus Henriette van Praag, Gerd Kempermann, Fred H. Gage · Nature Neuroscience | Mar 1999 | 3,922 |
| 14 | Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain Fiona K. Doetsch, Isabelle Caillé, Daniel A. Lim et al. · Cell | Jun 1999 | 3,915 |
| 15 | The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function Michael F. Egan, Masami Kojima, Joseph H. Callicott et al. · Cell | 2003 | 3,902 |
| 16 | Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. Ken D. McCarthy, Jean de Vellis · The Journal of Cell Biology | Jun 1980 | 3,901 |
| 17 | Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats Joseph Altman, Gopal D. Das · The Journal of Comparative Neurology | Jun 1965 | 3,588 |
| 18 | Physiology of Microglia Helmut Kettenmann, Uwe‐Karsten Hanisch, Mami Noda et al. · Physiological Reviews | Apr 2011 | 3,572 |
| 19 | More hippocampal neurons in adult mice living in an enriched environment Gerd Kempermann, H. Georg Kuhn, Fred H. Gage · Nature | Apr 1997 | 3,538 |
| 20 | Interneurons of the hippocampus Tamás F. Freund, György Buzsáki · Hippocampus | 7 Dec 1998 | 3,487 |
| 21 | A Neurotrophic Model for Stress-Related Mood Disorders Ronald S. Duman, Lisa M. Monteggia · Biological Psychiatry | 24 Apr 2006 | 3,385 |
| 22 | Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis HEIDI S. PHILLIPS, Samir Kharbanda, Ruihuan Chen et al. · Cancer Cell | Mar 2006 | 3,223 |
| 23 | Specification of Cerebral Cortical Areas PASKO T. RAKIC · Science | 8 Jul 1988 | 3,175 |
| 24 | Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation H. Georg Kuhn, Heather Dickinson-Anson, F H Gage · Journal of Neuroscience | 15 Mar 1996 | 3,149 |
| 25 | Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus Jessica E. Malberg, Amelia J. Eisch, Eric J. Nestler et al. · Journal of Neuroscience | 15 Dec 2000 | 3,132 |
| 26 | Cell Death During Development of the Nervous System Ronald W. Oppenheim · Annual Review of Neuroscience | Mar 1991 | 3,042 |
| 27 | Mechanisms and Functional Implications of Adult Neurogenesis Chunmei Zhao, Wei Deng, Fred H. Gage · Cell | Feb 2008 | 3,013 |
| 28 | Molecular Architecture of the Mouse Nervous System Amit Zeisel, Hannah Hochgerner, Peter Lönnerberg et al. · Cell | Aug 2018 | 2,981 |
| 29 | Running enhances neurogenesis, learning, and long-term potentiation in mice Henriette van Praag, Brian R. Christie, Terrence J. Sejnowski et al. · Proceedings of the National Academy of Sciences | 9 Nov 1999 | 2,918 |
| 30 | Functional neurogenesis in the adult hippocampus Henriette van Praag, Alejandro Fabián Schinder, Brian R. Christie et al. · Nature | Feb 2002 | 2,880 |
| 31 | Neuronal replacement from endogenous precursors in the adult brain after stroke Andreas Arvidsson, Tove Collin, Deniz Kirik et al. · Nature Medicine | 5 Aug 2002 | 2,831 |
| 32 | Exercise: a behavioral intervention to enhance brain health and plasticity Carl W. Cotman · Trends in Neurosciences | Jun 2002 | 2,741 |
| 33 | Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro Benjamin E. Reubinoff, Martín F. Pera, Chui‐Yee Fong et al. · Nature Biotechnology | Apr 2000 | 2,715 |
| 34 | Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions Guo‐li Ming, Hongjun Song · Neuron | May 2011 | 2,674 |
| 35 | Molecular dissection of reactive astrogliosis and glial scar formation Michael V. Sofroniew · Trends in Neurosciences | 25 Sep 2009 | 2,643 |
| 36 | Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma Rossella Galli, Elena Binda, Ugo Orfanelli et al. · Cancer Research | Oct 2004 | 2,608 |
| 37 | Tripartite synapses: glia, the unacknowledged partner Alfonso Araque, Vladimir Parpura, Rita P. Sanzgiri et al. · Trends in Neurosciences | May 1999 | 2,557 |
| 38 | Multiple Sclerosis Daniel S. Reich, Claudia Francesca Lucchinetti, Peter A. Calabresi · New England Journal of Medicine | 10 Jan 2018 | 2,532 |
| 39 | Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse Ye Zhang, Steven A. Sloan, Laura E. Clarke et al. · Neuron | 16 Dec 2015 | 2,532 |
| 40 | The Glial Nature of Embryonic and Adult Neural Stem Cells Arnold R. Kriegstein, Arturo Álvarez-Buylla · Annual Review of Neuroscience | Jun 2009 | 2,512 |
| 41 | Reactive astrocyte nomenclature, definitions, and future directions Carole Escartin et al. · Nature Neuroscience | 15 Feb 2021 | 2,503 |
| 42 | Reactive Astrocytes: Production, Function, and Therapeutic Potential Shane A. Liddelow, Ben A. Barres · Immunity | Jun 2017 | 2,452 |
| 43 | Inflammatory Blockade Restores Adult Hippocampal Neurogenesis Michelle Monje, Hiroki Toda, Theo D. Palmer · Science | 17 Nov 2003 | 2,432 |
| 44 | Adult rat and human bone marrow stromal cells differentiate into neurons Dale Woodbury, Emily J. Schwarz, Darwin J. Prockop et al. · Journal of Neuroscience Research | 2000 | 2,404 |
| 45 | Chondroitinase ABC promotes functional recovery after spinal cord injury Elizabeth J. Bradbury, Lawrence David Falcon Moon, Reena J. Popat et al. · Nature | Apr 2002 | 2,379 |
| 46 | Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled‐up primate brain Frederico A. C. Azevedo, Ludmila R.B. Carvalho, Lea T. Grinberg et al. · The Journal of Comparative Neurology | 18 Feb 2009 | 2,368 |
| 47 | Long-Distance Neuronal Migration in the Adult Mammalian Brain Carlos Lois, Arturo Álvarez-Buylla · Science | 20 May 1994 | 2,342 |
| 48 | Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination Gregory J. Brewer, John R. Torricelli, E. K. Evege et al. · Journal of Neuroscience Research | Aug 1993 | 2,342 |
| 49 | Exercise builds brain health: key roles of growth factor cascades and inflammation Carl W. Cotman, Nicole C. Berchtold, Lori‐Ann Christie · Trends in Neurosciences | Sep 2007 | 2,289 |
| 50 | Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases Stephen C. Noctor, Verónica Martínez‐Cerdeño, Lidija Ivic et al. · Nature Neuroscience | 2004 | 2,274 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.