Institution · Centre for Human Drug Research
Most cited papers from Centre for Human Drug Research
What are the most cited papers from Centre for Human Drug Research?
The most cited paper from Centre for Human Drug Research is "HMDB 5.0: the Human Metabolome Database for 2022" (David Scott Wishart et al., 2021), with 2,661 citations. Next come "International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors" (2,575) and "Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates" (1,871).
Showing 50 of 60 papers. Every paper with more than 361 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | HMDB 5.0: the Human Metabolome Database for 2022 David Scott Wishart et al. · Nucleic Acids Research | 20 Oct 2021 | 2,661 |
| 2 | International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors Bertil B. Fredholm, Adriaan P. IJzerman, Kenneth A. Jacobson et al. · Pharmacological Reviews | Dec 2001 | 2,575 |
| 3 | Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates Vasco Filipe, Andrea Hawe, Wim Jiskoot · Pharmaceutical Research | 3 Mar 2010 | 1,871 |
| 4 | The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist Veli‐Pekka Jaakola, Mark T. Griffith, Michael A. Hanson et al. · Science | 2 Oct 2008 | 1,789 |
| 5 | mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability Linde Schoenmaker, Dominik Witzigmann, Jayesh A. Kulkarni et al. · International Journal of Pharmaceutics | 8 Apr 2021 | 1,561 |
| 6 | Eleven grand challenges in single-cell data science David Lähnemann et al. · Genome biology | 7 Feb 2020 | 1,493 |
| 7 | Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0 Laurent Heirendt et al. · Nature Protocols | 20 Feb 2019 | 1,399 |
| 8 | International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update Bertil B. Fredholm, Adriaan P. IJzerman, Kenneth A. Jacobson et al. · Pharmacological Reviews | 15 Feb 2011 | 1,316 |
| 9 | Extrinsic Fluorescent Dyes as Tools for Protein Characterization Andrea Hawe, Marc Sutter, Wim Jiskoot · Pharmaceutical Research | 3 Jan 2008 | 1,207 |
| 10 | Titanium dioxide and zinc oxide nanoparticles in sunscreens: focus on their safety and effectiveness Threes G. M. Smijs, Pavel Pavel · Nanotechnology Science and Applications | Oct 2011 | 1,131 |
| 11 | Multivalent N -Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing Jayaprakash K. Nair et al. · Journal of the American Chemical Society | Dec 2014 | 1,126 |
| 12 | Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition Ruud S. Kootte et al. · Cell Metabolism | Oct 2017 | 1,051 |
| 13 | Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions Wei Liu, Eugene Chun, Aaron A. Thompson et al. · Science | 13 Jul 2012 | 978 |
| 14 | Analysis of a sleep-dependent neuronal feedback loop: the slow-wave microcontinuity of the EEG Bob Kemp, Aeilko H Zwinderman, Bert Tuk et al. · IEEE Transactions on Biomedical Engineering | 2000 | 963 |
| 15 | The Catharanthus Alkaloids:Pharmacognosy and Biotechnology Robert van der Heijden, Denise I. Jacobs, Wim Snoeijer et al. · Current Medicinal Chemistry | Mar 2004 | 733 |
| 16 | The influence of cytokines on the integrity of the blood-brain barrier in vitro Helga E. de Vries, Margret C.M. Blom-Roosemalen, Marijke van Oosten et al. · Journal of Neuroimmunology | 1996 | 677 |
| 17 | Maternal Care and Hippocampal Plasticity: Evidence for Experience-Dependent Structural Plasticity, Altered Synaptic Functioning, and Differential Responsiveness to Glucocorticoids and Stress Danielle L. Champagne, Rosemary C. Bagot, F. van Hasselt et al. · Journal of Neuroscience | 4 Jun 2008 | 665 |
| 18 | Reflections on univariate and multivariate analysis of metabolomics data Edoardo Saccenti, Huub C. J. Hoefsloot, Age K. Smilde et al. · Metabolomics | 25 Oct 2013 | 664 |
| 19 | Microneedle technologies for (trans)dermal drug and vaccine delivery Koen van der Maaden, Wim Jiskoot, Joke A. Bouwstra · Journal of Controlled Release | 4 Feb 2012 | 653 |
| 20 | Chitosan-based delivery systems for protein therapeutics and antigens Maryam Amidi, Enrico Mastrobattista, Wim Jiskoot et al. · Advanced Drug Delivery Reviews | 17 Nov 2009 | 617 |
| 21 | Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics Marie A.C. Depuydt et al. · Circulation Research | 28 Sep 2020 | 608 |
| 22 | Biotechnology for the production of plant secondary metabolites Robert Verpoorte, Adriana Contin, Johan Memelink · Phytochemistry Reviews | 2002 | 604 |
| 23 | Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality John F. Carpenter, Theodore W. Randolph, Wim Jiskoot et al. · Journal of Pharmaceutical Sciences | 14 Aug 2008 | 593 |
| 24 | MEMOTE for standardized genome-scale metabolic model testing Christian Lieven et al. · Nature Biotechnology | Mar 2020 | 572 |
| 25 | Promotion of sleep by targeting the orexin system in rats, dogs and humans Catherine Brisbare‐Roch, Jasper Dingemanse, Ralf Koberstein et al. · Nature Medicine | 28 Jan 2007 | 572 |
| 26 | The important role of stratum corneum lipids for the cutaneous barrier function Jeroen van Smeden, Michelle Janssens, G.S. Gooris et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 16 Nov 2013 | 546 |
| 27 | Screening out irrelevant cell-based models of disease Péter Horváth, Nathalie Aulner, Marc Bickle et al. · Nature Reviews Drug Discovery | 12 Sep 2016 | 536 |
| 28 | Liposomes and niosomes as topical drug carriers: dermal and transdermal drug delivery Hans Schreier, Joke A. Bouwstra · Journal of Controlled Release | Apr 1994 | 533 |
| 29 | Addressing the Cold Reality of mRNA Vaccine Stability Daan J.A. Crommelin, Thomas J. Anchordoquy, David B. Volkin et al. · Journal of Pharmaceutical Sciences | 13 Dec 2020 | 531 |
| 30 | Chitosans for gene delivery Gerrit Borchard · Advanced Drug Delivery Reviews | Nov 2001 | 531 |
| 31 | Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression Pieter Goossens, Juan Rodríguez‐Vita, Anders Etzerodt et al. · Cell Metabolism | 28 Mar 2019 | 524 |
| 32 | Metabolic network failures in Alzheimer's disease: A biochemical road map Jon B. Toledo et al. · Alzheimer s & Dementia | 21 Mar 2017 | 507 |
| 33 | Microfluidic 3D cell culture: from tools to tissue models Vincent van Duinen, Sebastiaan J. Trietsch, Jos Joore et al. · Current Opinion in Biotechnology | 18 Jun 2015 | 503 |
| 34 | Small molecule absorption by PDMS in the context of drug response bioassays Berend J. van Meer, Henk J. de Vries, Karl Firth et al. · Biochemical and Biophysical Research Communications | 14 Nov 2016 | 501 |
| 35 | Measuring thigmotaxis in larval zebrafish Stephanie J. Schnörr, Peter J. Steenbergen, Michael K. Richardson et al. · Behavioural Brain Research | 20 Dec 2011 | 490 |
| 36 | Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients Michelle Janssens, Jeroen van Smeden, Gert S. Gooris et al. · Journal of Lipid Research | Oct 2012 | 485 |
| 37 | Nasal mucociliary clearance as a factor in nasal drug delivery Emmeline Marttin, Nicolaas G. M. Schipper, J. Coos Verhoef et al. · Advanced Drug Delivery Reviews | 1998 | 469 |
| 38 | Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining In Kyung Rhee, Michiel van de Meent, Kornkanok Ingkaninan et al. · Journal of Chromatography A | Apr 2001 | 468 |
| 39 | Artificial intelligence for natural product drug discovery Michael W. Mullowney et al. · Nature Reviews Drug Discovery | 11 Sep 2023 | 460 |
| 40 | Chitosan and its derivatives in mucosal drug and vaccine delivery I.M. van der Lubben, J. Coos Verhoef, Gerrit Borchard et al. · European Journal of Pharmaceutical Sciences | Oct 2001 | 450 |
| 41 | Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels German Chronic Kidney Disease Study et al. · Nature Genetics | Oct 2019 | 442 |
| 42 | The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease Alberto Noronha et al. · Nucleic Acids Research | 10 Oct 2018 | 433 |
| 43 | The Blood-Brain Barrier in Neuroinflammatory Diseases Helga E. de Vries, Johan Kuiper, Albertus Gerrit de Boer et al. · Pharmacological Reviews | Jun 1997 | 433 |
| 44 | Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system Maryam Amidi, Stefan G. Romeijn, Gerrit Borchard et al. · Journal of Controlled Release | 28 Dec 2005 | 417 |
| 45 | Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics Thi Huyen Tram Nguyen, M‐S Mouksassi, Nicholas H. G. Holford et al. · CPT Pharmacometrics & Systems Pharmacology | 24 Nov 2016 | 404 |
| 46 | Fundamentals and developments in fluorescence-guided cancer surgery J. Sven D. Mieog, Friso B. Achterberg, Aimen Zlitni et al. · Nature Reviews Clinical Oncology | 7 Sep 2021 | 398 |
| 47 | Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development Robert Verpoorte · Drug Discovery Today | May 1998 | 396 |
| 48 | The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. III: Effects of chitosan-glutamate and carbomer on epithelial tight junctions in vitro Gerrit Borchard, Henrik L. Lueβen, Albertus Gerrit de Boer et al. · Journal of Controlled Release | May 1996 | 395 |
| 49 | Δ9-Tetrahydrocannabinol Induces Dopamine Release in the Human Striatum Matthijs Geert Bossong, Bart N.M. van Berckel, Ronald Boellaard et al. · Neuropsychopharmacology | 27 Aug 2008 | 393 |
| 50 | A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals Joris Deelen et al. · Nature Communications | 20 Aug 2019 | 392 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.