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Research facility · Leiden · Netherlands

Centre for Human Drug Research

In research, Centre for Human Drug Research stands highest in Medicine (#3,082 of 8,541 worldwide), Health Sciences (#3,715 of 9,902 worldwide) and Life Sciences (#3,310 of 6,403 worldwide), 2022-now. Relative to its size it is most specialised in Immunology and Immunology and Microbiology (Immunology is 13.9× its share of world research).

chdr.nlROR OpenAlex
World rank, 2022-now
#10,619
of 22,385 · #4,145 all time
Rank in Netherlands
#99
of 197
Research works
1.7k
▲ 5% vs 2018-21
Citations
75k
43.4 per fractional work
Top-10% rate
13.9%
all institutions 10.0%
vs its own fields
1.07×
1.00× is exactly expected
Open access
52%
world 40%
International
36%
world 18%
Centre for Human Drug Research

What is Centre for Human Drug Research known for in research?

The fields where it stands highest, 2022-now, ranked among every institution above the floor in each field.

FieldWorld rankWhere that sitsTop-10% rateWorksAll time
MedicineField #3,082 of 8,541 12.9%101 #1566
Health SciencesDomain #3,715 of 9,902 12.9%106 #1704
Life SciencesDomain #3,310 of 6,403 13.3%119 #1973
Biochemistry, Genetics and Molecular BiologyField #1,560 of 2,964 15.3%66 #1646

Each strip is that field's whole ranked pool, with the notch where Centre for Human Drug Research sits in it, in the colour of the band that rank falls in. The track under the rate is the rate itself: it carries no average mark, because the average differs by field (from about 6% in Dentistry to 21% in Economics).

Which of those standings moved

The same fields on both windows: where it stood over the whole record, and where it stands in 2022-now. The distance is the story, and it is the one thing the two rank columns above cannot show.

  1. Medicine#1,566 #3,082
  2. Health Sciences#1,704 #3,715
  3. Life Sciences#1,973 #3,310
  4. Biochemistry, Genetics and Molecular Biology#1,646 #1,560
all time2022-now, better2022-now, worse

A dot further right is a better standing. Fields it was not ranked in over the whole record are left out.

Which fields of science does Centre for Human Drug Research work in?

In 2022-now, 44% of research at Centre for Human Drug Research is in Life Sciences, 39% in Health Sciences. Its largest fields are Medicine (37%), Biochemistry, Genetics and Molecular Biology (24%), Immunology and Microbiology (10%). It does 3.1× the world's share of Life Sciences.

Life Sciences: 136 fractional works · 43.5% of its workBiochemistry, Genetics and Molecular Biology: 76 fractional works · 24.2% of its workMolecular Biology: 54 fractional works · 17.1% of its workGenetics: 5 fractional works · 1.7% of its workCancer Research: 5 fractional works · 1.5% of its workCell Biology: 4 fractional works · 1.2% of its workPhysiology: 2 fractional works · 0.6% of its workBiotechnology: 2 fractional works · 0.5% of its workMolecular Medicine: 2 fractional works · 0.5% of its workBiophysics: 1 fractional works · 0.4% of its workBiochemistry: 1 fractional works · 0.4% of its workClinical Biochemistry: 1 fractional works · 0.2% of its workImmunology and Microbiology: 32 fractional works · 10.2% of its workImmunology: 30 fractional works · 9.6% of its workMicrobiology: 2 fractional works · 0.5% of its workSmaller subfields together: 0 fractional works · 0.1% of its workNeuroscience: 16 fractional works · 5.0% of its workCellular and Molecular Neuroscience: 7 fractional works · 2.2% of its workNeurology: 2 fractional works · 0.7% of its workCognitive Neuroscience: 2 fractional works · 0.7% of its workEndocrine and Autonomic Systems: 2 fractional works · 0.5% of its workBiological Psychiatry: 1 fractional works · 0.4% of its workSensory Systems: 1 fractional works · 0.3% of its workSmaller subfields together: 1 fractional works · 0.2% of its workPharmacology, Toxicology and Pharmaceutics: 9 fractional works · 3.0% of its workPharmacology: 6 fractional works · 1.9% of its workPharmaceutical Science: 2 fractional works · 0.7% of its workToxicology: 1 fractional works · 0.4% of its workAgricultural and Biological Sciences: 3 fractional works · 1.1% of its workPlant Science: 1 fractional works · 0.3% of its workFood Science: 1 fractional works · 0.3% of its workAnimal Science and Zoology: 1 fractional works · 0.3% of its workSmaller subfields together: 1 fractional works · 0.2% of its workHealth Sciences: 121 fractional works · 38.8% of its workMedicine: 116 fractional works · 37.1% of its workOncology: 14 fractional works · 4.4% of its workEpidemiology: 11 fractional works · 3.5% of its workPharmacology: 10 fractional works · 3.1% of its workPhysiology: 8 fractional works · 2.4% of its workNeurology: 7 fractional works · 2.3% of its workRadiology, Nuclear Medicine and Imaging: 6 fractional works · 2.1% of its workPulmonary and Respiratory Medicine: 6 fractional works · 2.0% of its workInfectious Diseases: 6 fractional works · 1.9% of its workSurgery: 6 fractional works · 1.9% of its workDermatology: 5 fractional works · 1.5% of its workCardiology and Cardiovascular Medicine: 5 fractional works · 1.5% of its workPsychiatry and Mental health: 4 fractional works · 1.4% of its workPublic Health, Environmental and Occupational Health: 3 fractional works · 1.1% of its workEndocrinology, Diabetes and Metabolism: 3 fractional works · 1.0% of its workImmunology and Allergy: 3 fractional works · 0.9% of its workRheumatology: 2 fractional works · 0.8% of its workAnesthesiology and Pain Medicine: 2 fractional works · 0.7% of its workPathology and Forensic Medicine: 2 fractional works · 0.7% of its workPediatrics, Perinatology and Child Health: 2 fractional works · 0.6% of its workNephrology: 1 fractional works · 0.4% of its workHepatology: 1 fractional works · 0.4% of its workTransplantation: 1 fractional works · 0.3% of its workRehabilitation: 1 fractional works · 0.3% of its workEmergency Medicine: 1 fractional works · 0.3% of its workGenetics: 1 fractional works · 0.3% of its workOphthalmology: 1 fractional works · 0.3% of its workGastroenterology: 1 fractional works · 0.2% of its workSmaller subfields together: 3 fractional works · 0.9% of its workHealth Professions: 3 fractional works · 0.8% of its workGeneral Health Professions: 1 fractional works · 0.3% of its workSmaller subfields together: 2 fractional works · 0.6% of its workVeterinary: 2 fractional works · 0.6% of its workSmall Animals: 2 fractional works · 0.6% of its workNursing: 1 fractional works · 0.3% of its workNutrition and Dietetics: 1 fractional works · 0.3% of its workPhysical Sciences: 47 fractional works · 15.2% of its workEngineering: 11 fractional works · 3.6% of its workBiomedical Engineering: 10 fractional works · 3.1% of its workSmaller subfields together: 1 fractional works · 0.5% of its workChemistry: 10 fractional works · 3.2% of its workOrganic Chemistry: 5 fractional works · 1.6% of its workSpectroscopy: 4 fractional works · 1.3% of its workSmaller subfields together: 1 fractional works · 0.4% of its workComputer Science: 9 fractional works · 2.9% of its workComputational Theory and Mathematics: 8 fractional works · 2.4% of its workInformation Systems: 1 fractional works · 0.2% of its workArtificial Intelligence: 1 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.1% of its workMaterials Science: 9 fractional works · 2.7% of its workBiomaterials: 4 fractional works · 1.3% of its workMaterials Chemistry: 3 fractional works · 0.8% of its workSurfaces, Coatings and Films: 1 fractional works · 0.2% of its workSmaller subfields together: 1 fractional works · 0.3% of its workMathematics: 4 fractional works · 1.4% of its workStatistics and Probability: 4 fractional works · 1.1% of its workModeling and Simulation: 1 fractional works · 0.2% of its workEnvironmental Science: 2 fractional works · 0.6% of its workHealth, Toxicology and Mutagenesis: 1 fractional works · 0.3% of its workSmaller subfields together: 1 fractional works · 0.3% of its workPhysics and Astronomy: 2 fractional works · 0.5% of its workAtomic and Molecular Physics, and Optics: 1 fractional works · 0.4% of its workSmaller subfields together: 1 fractional works · 0.2% of its workChemical Engineering: 0 fractional works · 0.1% of its workEnergy: 0 fractional works · 0.1% of its workEarth and Planetary Sciences: 0 fractional works · 0.0% of its workSocial Sciences: 8 fractional works · 2.5% of its workPsychology: 4 fractional works · 1.4% of its workExperimental and Cognitive Psychology: 2 fractional works · 0.7% of its workClinical Psychology: 2 fractional works · 0.6% of its workSmaller subfields together: 0 fractional works · 0.1% of its workEconomics, Econometrics and Finance: 1 fractional works · 0.4% of its workEconomics and Econometrics: 1 fractional works · 0.4% of its workDecision Sciences: 1 fractional works · 0.4% of its workInformation Systems and Management: 1 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.1% of its workSocial Sciences: 1 fractional works · 0.3% of its workArts and Humanities: 0 fractional works · 0.1% of its workALL ITS WORKCentre for HumanDrug Research313fractional works, 2022-now
Life Sciences44%Physical Sciences15%Health Sciences39%Social Sciences3%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in 2022-now. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 25 fields, with their numbers
    1. Biochemistry, Genetics and Molecular Biology7624.2%
    2. Immunology and Microbiology3210.2%
    3. Neuroscience165.0%
    4. Pharmacology, Toxicology and Pharmaceutics93.0%
    5. Agricultural and Biological Sciences31.1%
    1. Medicine11637.1%
    2. Health Professions30.8%
    3. Veterinary20.6%
    4. Nursing10.3%
    1. Engineering113.6%
    2. Chemistry103.2%
    3. Computer Science92.9%
    4. Materials Science92.7%
    5. Mathematics41.4%
    6. Environmental Science20.6%
    7. Physics and Astronomy20.5%
    8. Chemical Engineering00.1%
    9. Energy00.1%
    10. Earth and Planetary Sciences00.0%
    1. Psychology41.4%
    2. Economics, Econometrics and Finance10.4%
    3. Decision Sciences10.4%
    4. Social Sciences10.3%
    5. Arts and Humanities00.1%
    6. Business, Management and Accounting00.0%
All of science, and how each field's share has moved since 1950: the Science domain explorer

What does Centre for Human Drug Research specialise in?

Where its research is concentrated relative to its size: Immunology takes 13.9× the share of its output that it takes of world research.

  1. ImmunologySubfield · 30.0 works14×
  2. Immunology and MicrobiologyField · 31.9 works10×
← less than its size predicts1×more →

Location quotient, a volume reading rather than an impact one. It surfaces small, lopsided specialities.

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 0.23× its world share, 4 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 4.54× its world share, 76 worksBiochemistry, Geneti…Immunology and Microbiology: 10.13× its world share, 32 worksImmunology and Micro…Neuroscience: 3.09× its world share, 16 worksNeurosciencePharmacology, Toxicology and Pharmaceutics: 8.44× its world share, 9 worksPharmacology, Toxico…Chemical Engineering: 0.28× its world share, 0 worksChemical EngineeringChemistry: 2.07× its world share, 10 worksChemistryComputer Science: 0.38× its world share, 9 worksComputer ScienceEarth and Planetary Sciences: 0.02× its world share, 0 worksEarth and Planetary …Energy: 0.06× its world share, 0 worksEnergyEngineering: 0.24× its world share, 11 worksEngineeringEnvironmental Science: 0.11× its world share, 2 worksEnvironmental ScienceMaterials Science: 0.79× its world share, 9 worksMaterials ScienceMathematics: 1.17× its world share, 4 worksMathematicsPhysics and Astronomy: 0.24× its world share, 2 worksPhysics and AstronomyHealth Professions: 0.31× its world share, 3 worksHealth ProfessionsMedicine: 1.93× its world share, 116 worksMedicineNursing: 0.67× its world share, 1 worksNursingVeterinary: 4.33× its world share, 2 worksVeterinaryArts and Humanities: 0.03× its world share, 0 worksArts and HumanitiesDecision Sciences: 0.37× its world share, 1 worksDecision SciencesEconomics, Econometrics and Finance: 0.17× its world share, 1 worksEconomics, Econometr…Psychology: 0.45× its world share, 4 worksPsychologySocial Sciences: 0.03× its world share, 1 worksSocial Sciences1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Immunology and Microbiology, 10.1×. Every wedge is a field page.

All 24 fields, with their numbers
  1. Immunology and Microbiology10.13×32 works
  2. Pharmacology, Toxicology and Pharmaceutics8.44×9 works
  3. Biochemistry, Genetics and Molecular Biology4.54×76 works
  4. Veterinary4.33×2 works
  5. Neuroscience3.09×16 works
  6. Chemistry2.07×10 works
  7. Medicine1.93×116 works
  8. Mathematics1.17×4 works
  9. Materials Science0.79×9 works
  10. Nursing0.67×1 works
  11. Psychology0.45×4 works
  12. Computer Science0.38×9 works
  13. Decision Sciences0.37×1 works
  14. Health Professions0.31×3 works
  15. Chemical Engineering0.28×0 works
  16. Engineering0.24×11 works
  17. Physics and Astronomy0.24×2 works
  18. Agricultural and Biological Sciences0.23×4 works
  19. Economics, Econometrics and Finance0.17×1 works
  20. Environmental Science0.11×2 works
  21. Energy0.06×0 works
  22. Arts and Humanities0.03×0 works
  23. Social Sciences0.03×1 works
  24. Earth and Planetary Sciences0.02×0 works

Who are the top researchers at Centre for Human Drug Research?

Ranked on the quality score, Gerard J. P. van Westen, Jules A. A. C. Heuberger and J. G. Coen van Hasselt lead among researchers whose main affiliation is Centre for Human Drug Research.

  1. 1 Gerard J. P. van Westen Netherlands · #289,767 worldwide 6.6k citations · 269 works
  2. 2 Jules A. A. C. Heuberger Netherlands · #311,572 worldwide 1.6k citations · 65 works
  3. 3 J. G. Coen van Hasselt Netherlands · #378,085 worldwide 4.2k citations · 178 works
  4. 4 Martijn L. Manson Netherlands · #636,127 worldwide 1k citations · 36 works
  5. 5 Jacobus Burggraaf Netherlands · #659,548 worldwide 10k citations · 369 works
  6. 6 Emilie M.J. van Brummelen Netherlands · #698,214 worldwide 4.8k citations · 64 works
  7. 7 Lineke Zuurman Netherlands · #739,194 worldwide 1.6k citations · 41 works
  8. 8 Leo Price Netherlands · #756,056 worldwide 5.1k citations · 132 works
  9. 9 Heyang Zhang Netherlands · #987,671 worldwide 983 citations · 62 works
  10. 10 Geert Jan Groeneveld Netherlands · #993,485 worldwide 5.1k citations · 220 works
All ranked researchers at Centre for Human Drug Research

What are the most cited papers from Centre for Human Drug Research?

The most cited paper from Centre for Human Drug Research is "HMDB 5.0: the Human Metabolome Database for 2022" (David Scott Wishart et al., 2021), with 2,661 citations. Next come "International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors" (2,575) and "Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates" (1,871).

Most cited papers
#PaperReleasedCitations
1 HMDB 5.0: the Human Metabolome Database for 2022 David Scott Wishart et al. · Nucleic Acids Research Open access 20 Oct 2021 2,661
2 International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors Bertil B. Fredholm, Adriaan P. IJzerman, Kenneth A. Jacobson et al. · Pharmacological Reviews Open access Dec 2001 2,575
3 Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates Vasco Filipe, Andrea Hawe, Wim Jiskoot · Pharmaceutical Research Open access 3 Mar 2010 1,871
4 The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist Veli‐Pekka Jaakola, Mark T. Griffith, Michael A. Hanson et al. · Science Open access 2 Oct 2008 1,789
5 mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability Linde Schoenmaker, Dominik Witzigmann, Jayesh A. Kulkarni et al. · International Journal of Pharmaceutics Open access 8 Apr 2021 1,561
All 60 most cited papers, with filters and sorting

Which keywords describe research at Centre for Human Drug Research?

By fractional works in 2022-now, weighted toward what it does more of than the world: Inflammation, Immune Response, Cytokines, Pharmacokinetics, Dendritic Cells, Atherosclerosis, Regulatory T Cells and Biomarkers.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in 2022-now in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Inflammation37▲ 5.6×62 topics
  2. Epidemiology19▲ 1.50×60 topics
  3. Cancer15▲ 3.5×37 topics
  4. Immune Response14▲ 8.1×16 topics
  5. Oxidative Stress14▲ 2.7×40 topics
  6. Cytokines12▲ 14×7 topics
  7. Pharmacokinetics12▲ 15×5 topics
  8. Biomarkers12▲ 5.5×13 topics
  9. Dendritic Cells12▲ 43×2 topics
  10. Atherosclerosis11▲ 12×10 topics
  11. Regulatory T Cells10▲ 29×4 topics
  12. T Cell Activation10▲ 80×2 topics
  13. Immunity9▲ 7.2×8 topics
  14. Immunotherapy9▲ 3.9×14 topics
  15. Drug Discovery8▲ 12×7 topics
  16. Medicinal Chemistry8▲ 9.8×7 topics
  17. Depression8▲ 3.0×11 topics
  18. Adaptive Immunity8▲ 111×1 topic
  19. Oxidized LDL8▲ 111×1 topic
  20. Neurological Disorders8▲ 4.4×14 topics
  21. Molecular Docking8▲ 20×2 topics
  22. Cancer Therapy7▲ 4.1×16 topics
  23. Drug Target Identification7▲ 25×1 topic
  24. Mass Spectrometry7▲ 15×4 topics
  25. Virtual Screening7▲ 25×1 topic
  26. Cell Signaling7▲ 14×8 topics
  27. Angiogenesis7▲ 6.5×13 topics
  28. Innate Immunity7▲ 6.6×11 topics
  29. Mitochondrial Dysfunction6▲ 7.0×12 topics
  30. Gene Therapy6▲ 10×4 topics
  31. Monoclonal Antibodies6▲ 22×3 topics
  32. Data Analysis6▲ 7.2×4 topics
  33. Tumor Targeting6▲ 10×3 topics
  34. Nuclear Receptors6▲ 20×5 topics
  35. Cancer Immunotherapy6▲ 11×3 topics
  36. Antigen Presentation5▲ 19×2 topics
  37. Crystal Structure5▲ 12×2 topics
  38. Signal Transduction5▲ 11×4 topics
  39. Glycosylation5▲ 15×3 topics
  40. Molecular Mechanisms5▲ 18×4 topics

Which research topics does Centre for Human Drug Research publish most on?

By volume in 2022-now: Atherosclerosis and Cardiovascular Diseases, Computational Drug Discovery Methods, Metabolomics and Mass Spectrometry Studies and Receptor Mechanisms and Signaling.

Atherosclerosis and Cardiovascular Diseases: 8 fractional worksComputational Drug Discovery Methods: 7 fractional worksMetabolomics and Mass Spectrometry Studies: 4 fractional worksReceptor Mechanisms and Signaling: 4 fractional worksMonoclonal and Polyclonal Antibodies Research: 4 fractional worksImmunotherapy and Immune Responses: 4 fractional worksPharmacogenetics and Dru…4Pharmacogenetics and Drug Metabolism: 4 fractional worksAntibiotics Pharmacokinetics and Efficacy: 3 fractional worksDrug Transport and Resistance Mechanisms: 3 fractional worksRNA Interference and Gen…3RNA Interference and Gene Delivery: 3 fractional works
ImmunologyComputational Theory and MathematicsMolecular BiologyRadiology, Nuclear Medicine and Imaging2 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 Atherosclerosis and Cardiovascular Diseases Immunology 8 works
  2. 2 Computational Drug Discovery Methods Computational Theory and Mathematics 7 works
  3. 3 Metabolomics and Mass Spectrometry Studies Molecular Biology 4 works
  4. 4 Receptor Mechanisms and Signaling Molecular Biology 4 works
  5. 5 Monoclonal and Polyclonal Antibodies Research Radiology, Nuclear Medicine and Imaging 4 works
  6. 6 Immunotherapy and Immune Responses Immunology 4 works
  7. 7 Pharmacogenetics and Drug Metabolism Pharmacology 4 works
  8. 8 Antibiotics Pharmacokinetics and Efficacy Pharmacology 3 works
  9. 9 Drug Transport and Resistance Mechanisms Oncology 3 works
  10. 10 RNA Interference and Gene Delivery Molecular Biology 3 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available52.0%not open48.0%

World: 40% of research is openly available.

with international co-authors35.6%domestic only64.4%

World: 18% is written across borders.

How has Centre for Human Drug Research's research output changed?

Output in 2022-2025 was 5% higher than in 2018-2021.

still counting1990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Centre for Human Drug Research as a percentage of every work published that year, 0.0012% in 2024.

still counting0.0020%0.0040%0.0060%Centre for Human Drug Research0.0012% in 202519801990200020102020

Fractional works of Centre for Human Drug Research over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year, against all institutions in the same year.

still counting10%20%30%Centre for Human Drug Research13.1% in 2025all institutions10.0% in 2025200020102020

Of each year's output, the share that reached the world's 10% most cited for its field and year. Peak 22.8% in 2001.

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