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Institution · Charles River Laboratories (United States)

Most cited papers from Charles River Laboratories (United States)

Charles River Laboratories (United States)

What are the most cited papers from Charles River Laboratories (United States)?

The most cited paper from Charles River Laboratories (United States) is "Vaginal Cytology of the Laboratory Rat and Mouse" (Michelle C. Cora, Linda H. Kooistra, Greg S. Travlos, 2015), with 1,026 citations. Next come "Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease" (842) and "Protein misfolding in neurodegenerative diseases: implications and strategies" (695).

Showing 50 of 60 papers. Every paper with more than 106 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Vaginal Cytology of the Laboratory Rat and Mouse Michelle C. Cora, Linda H. Kooistra, Greg S. Travlos · Toxicologic Pathology Open access 3 Mar 2015 1,026
2 Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease Jin‐Kuk Kim et al. · New England Journal of Medicine Open access 9 Oct 2019 842
3 Protein misfolding in neurodegenerative diseases: implications and strategies Patrick R. Sweeney, Hyunsun Park, Marc H. BAUMANN et al. · Translational Neurodegeneration Open access 13 Mar 2017 695
4 FELASA recommendations for the health monitoring of mouse, rat, hamster, guinea pig and rabbit colonies in breeding and experimental units FELASA working group on revision of guidelines for health monitoring of rodents , Michael Mähler, Marion Berard et al. · Laboratory Animals Open access 4 Feb 2014 672
5 Proposal of a 2-Tier Histologic Grading System for Canine Cutaneous Mast Cell Tumors to More Accurately Predict Biological Behavior Matti Kiupel et al. · Veterinary Pathology Open access 9 Nov 2010 616
6 Pathological Changes During Aging in, Barrier-Reared Fischer 344 Male Rats Gerald L. Coleman, Stephen W. Barthold, George W. Osbaldiston et al. · Journal of Gerontology Open access May 1977 523
7 Generation and characterization of LymphoStat‐B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator Kevin P. Baker et al. · Arthritis & Rheumatism Nov 2003 499
8 Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. Annarosa Leri, Pier Paolo Claudio, Qingxiangzi Li et al. · Journal of Clinical Investigation Open access Apr 1998 457
9 A 90-day oral gavage toxicity study of d-methylphenidate and d,l-methylphenidate in Sprague–Dawley rats Steve Teo, David Stirling, Steve D. Thomas et al. · Toxicology Oct 2002 346
10 Death after High-Dose rAAV9 Gene Therapy in a Patient with Duchenne’s Muscular Dystrophy Angela Lek et al. · New England Journal of Medicine Open access 27 Sep 2023 323
11 Neonatal mortality from in utero exposure to perfluorooctanesulfonate (PFOS) in Sprague–Dawley rats: Dose–response, and biochemical and pharamacokinetic parameters Deanna J. Luebker, Raymond G. York, Kristen J. Hansen et al. · Toxicology 30 Aug 2005 315
12 The iron chelator deferasirox protects mice from mucormycosis through iron starvation Ashraf S. Ibrahim, Teclegiorgis Gebermariam, Yue Fu et al. · Journal of Clinical Investigation Open access 4 Sep 2007 310
13 Immunological Variation Between Inbred Laboratory Mouse Strains Rani S. Sellers, Charles B. Clifford, Piper M. Treuting et al. · Veterinary Pathology 30 Nov 2011 293
14 Recent Advances in Lipid-Based Vesicles and Particulate Carriers for Topical and Transdermal Application Shashank Sharma B. C. Jain, Niketkumar Patel, Mansi K. Shah et al. · Journal of Pharmaceutical Sciences 16 Nov 2016 283
15 Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium Terrence F. Meehan et al. · Nature Genetics Open access 26 Jun 2017 274
16 Two-generation reproduction and cross-foster studies of perfluorooctanesulfonate (PFOS) in rats Deanna J. Luebker, Marvin T. Case, Raymond G. York et al. · Toxicology 17 Sep 2005 274
17 Murine Noroviruses Comprising a Single Genogroup Exhibit Biological Diversity despite Limited Sequence Divergence Larissa B. Thackray, Christiane E. Wobus, Karen A. Chachu et al. · Journal of Virology Open access 25 Jul 2007 273
18 Epigenetics and the Environment Jessica E. Sutherland, Max Costa · Annals of the New York Academy of Sciences Mar 2003 264
19 Safety and Efficacy of Chimeric Yellow Fever-Dengue Virus Tetravalent Vaccine Formulations in Nonhuman Primates Farshad Guirakhoo, Konstantin V. Pugachev, Z. Zhang et al. · Journal of Virology Open access 12 Apr 2004 256
20 Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment Charlotte Fenton McDonagh, Eileen Turcott, Lori Westendorf et al. · Protein Engineering Design and Selection Open access 18 Apr 2006 242
21 Contemporary prevalence of infectious agents in laboratory mice and rats Kathleen R. Pritchett‐Corning, Janice Cosentino, Charles B. Clifford · Laboratory Animals 12 Mar 2009 241
22 Evaluation of Cell Proliferation in Rat Tissues with BrdU, PCNA, Ki-67(MIB-5) Immunohistochemistry and In Situ Hybridization for Histone mRNA Levan Muskhelishvili, John R. Latendresse, Ralph L. Kodell et al. · Journal of Histochemistry & Cytochemistry Dec 2003 237
23 Histology Atlas of the Developing Prenatal and Postnatal Mouse Central Nervous System, with Emphasis on Prenatal Days E7.5 to E18.5 Vivian S. Chen, James P. Morrison, Myra F. Southwell et al. · Toxicologic Pathology Open access Aug 2017 225
24 Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses Ying Chan et al. · Science Translational Medicine Open access 10 Feb 2021 217
25 Biology and Diseases of Rats Glen M. Otto, Craig L. Franklin, Charles B. Clifford · Elsevier eBooks Book chapterOpen access 2015 210
26 Heat or Insulation: Behavioral Titration of Mouse Preference for Warmth or Access to a Nest Brianna N. Gaskill, Christopher J. Gordon, Edmond Anthony Pajor et al. · PLoS ONE Open access 30 Mar 2012 208
27 Critical Time Window for Intra-Arrest Cooling With Cold Saline Flush in a Dog Model of Cardiopulmonary Resuscitation Ala Nozari, Peter J. Safar, S. William Stezoski et al. · Circulation 12 Jun 2006 205
28 Anaesthetic effects of chloral hydrate, pentobarbitone and urethane in adult male rats Karl J. Field, William J. White, C. Max Lang · Laboratory Animals Jul 1993 201
29 Impact of nesting material on mouse body temperature and physiology Brianna N. Gaskill, Christopher James Gordon, Edmond Anthony Pajor et al. · Physiology & Behavior 9 Jan 2013 198
30 Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques Thomas A. Waldmann, Enrico Lugli, Mario Roederer et al. · Blood Open access 8 Mar 2011 195
31 Subcellular redistribution of lysosomal enzymes during caerulein-induced pancreatitis A. Saluja, Shuichi Hashimoto, Manika Saluja et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology Oct 1987 191
32 The role of the N-methyl-d-aspartate receptor in ketamine-induced apoptosis in rat forebrain culture Chao Wang, Natalya Sadovova, X. Fu et al. · Neuroscience 2005 190
33 Assessment of an In Silico Mechanistic Model for Proarrhythmia Risk Prediction Under the Ci PA Initiative Zhihua Li, Bradley J. Ridder, Xiaomei Han et al. · Clinical Pharmacology & Therapeutics Open access 27 Aug 2018 186
34 Urinary biomarkers trefoil factor 3 and albumin enable early detection of kidney tubular injury Yan Yu, Hong Lan Jin, Daniel Holder et al. · Nature Biotechnology May 2010 186
35 Induction of Type I Diabetes by Kilham's Rat Virus in Diabetes-Resistant BB/Wor Rats Dennis L. Guberski, V. A. Thomas, W. R. Shek et al. · Science 15 Nov 1991 183
36 Stimulation of lymphokine release from T lymphoblasts. Requirement for mRNA synthesis and inhibition by cyclosporin A. Angela Granelli‐Piperno, Kensuke Inaba, Ralph M. Steinman · The Journal of Experimental Medicine Open access Dec 1984 173
37 Tumorigenicity assessment of cell therapy products: The need for global consensus and points to consider Yoji Sato, Hideaki Bando, Matteo Piazza et al. · Cytotherapy Open access Nov 2019 170
38 Preclinical Safety Evaluation of AAV2-sFLT01— A Gene Therapy for Age-related Macular Degeneration Timothy K. MacLachlan, Michael Lukason, Margaret E. Collins et al. · Molecular Therapy Open access 30 Nov 2010 168
39 Gene Transfer with AAV9-PHP.B Rescues Hearing in a Mouse Model of Usher Syndrome 3A and Transduces Hair Cells in a Non-human Primate Bence György, Elise J. Meijer, Maryna V. Ivanchenko et al. · Molecular Therapy — Methods & Clinical Development Open access 20 Nov 2018 160
40 Neurovirulence properties of recombinant vesicular stomatitis virus vectors in non-human primates J. Erik Johnson, Farooq Nasar, John W. Coleman et al. · Virology Open access 14 Nov 2006 160
41 Developmental and reproductive toxicology studies in nonhuman primates Gary J. Chellman, Jeanine L. Bussiere, Norbert Makori et al. · Birth Defects Research Part B Developmental and Reproductive Toxicology Dec 2009 159
42 A Phase II Study of Depsipeptide in Refractory Metastatic Renal Cell Cancer Walter Michael Stadler, Kim Allyson Margolin, Sandy Ferber et al. · Clinical Genitourinary Cancer Jun 2006 153
43 Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2- a ]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis Nicolas Desroy et al. · Journal of Medicinal Chemistry Open access 17 Apr 2017 141
44 The historical aspects of sunscreens Frederick L. Urbach · Journal of Photochemistry and Photobiology B Biology Nov 2001 140
45 Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders Marina Pavlou, Christian Schön, Laurence Mireille Occelli et al. · EMBO Molecular Medicine Open access 22 Feb 2021 139
46 Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies Diana W. Shineman, Guriqbal S. Basi, Jennifer L. Bizon et al. · Alzheimer s Research & Therapy Open access 2011 137
47 Pharmaceutical toxicology: Designing studies to reduce animal use, while maximizing human translation Kathryn L. Chapman, Henry H. Holzgrefe, Lauren E. Black et al. · Regulatory Toxicology and Pharmacology Open access 21 Mar 2013 137
48 Dorsal tegmental dopamine neurons gate associative learning of fear Florian Groessl, Thomas Munsch, Susanne Meis et al. · Nature Neuroscience Open access 26 Jun 2018 133
49 Further characterization of marek's disease virus‐infected lymphocytes. I. In vivo infection B. W. Calnek, K. A. Schat, L. J. N. Ross et al. · International Journal of Cancer 15 Mar 1984 131
50 Models of Affiliative Relationships Among Free-Ranging Rhesus Monkeys (Macaca Mulatta) Ellen Kapsalis, Carol M. Berman · Behaviour 1996 123

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.