Most cited papers from Codexis (United States)

Codexis (United States)

What are the most cited papers from Codexis (United States)?

The most cited paper from Codexis (United States) is "Engineering the third wave of biocatalysis" (Uwe T. Bornscheuer, Gjalt W. Huisman, Romas J. Kazlauskas et al., 2012), with 2,648 citations. Next come "Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture" (1,771) and "Input Versus Output Queueing on a Space-Division Packet Switch" (1,483).

Published TypeFieldAccessCitations

Showing 50 of 59 papers. Every paper with more than 65 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Engineering the third wave of biocatalysis Uwe T. Bornscheuer, Gjalt W. Huisman, Romas J. Kazlauskas et al. · Nature	May 2012	2,648
2	Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture Christopher K. Savile, Jacob M. Janey, Emily C. Mundorff et al. · Science	17 Jun 2010	1,771
3	Input Versus Output Queueing on a Space-Division Packet Switch M.J. Karol, Michael G. Hluchyj, Samuel Morgan · IRE Transactions on Communications Systems	Dec 1987	1,483
4	Efficient Modulation for Band-Limited Channels G. David Forney, Robert G. Gallager, G.R. Lang et al. · IEEE Journal on Selected Areas in Communications	Sep 1984	733
5	From nature to industry: Harnessing enzymes for biocatalysis Rebecca Buller, Stefan Zoltan Lutz, Romas J. Kazlauskas et al. · Science Open access	23 Nov 2023	699
6	Design of an in vitro biocatalytic cascade for the manufacture of islatravir Mark A. Huffman et al. · Science	5 Dec 2019	663
7	The Knockout Switch: A Simple, Modular Architecture for High-Performance Packet Switching Yu-Shuan Yeh, Michael G. Hluchyj, Anthony S. Acampora · IEEE Journal on Selected Areas in Communications	Oct 1987	648
8	Coset codes. I. Introduction and geometrical classification G. David Forney · IEEE Transactions on Information Theory	Sep 1988	627
9	Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited Marian C. Bryan, Peter J. Dunn, David A. Entwistle et al. · Green Chemistry Open access	2018	625
10	Improving catalytic function by ProSAR-driven enzyme evolution Richard J. Fox, Sarah C. Davis, Emily C. Mundorff et al. · Nature Biotechnology	18 Feb 2007	561
11	Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxofylline Robert M. Strieter, Daniel George Remick, Peter A. Ward et al. · Biochemical and Biophysical Research Communications	Sep 1988	561
12	Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona John E. Blume et al. · Nature Communications Open access	22 Jul 2020	480
13	A green-by-design biocatalytic process for atorvastatin intermediate K. Steven, John M. Gruber, Christopher Davis et al. · Green Chemistry	3 Nov 2009	439
14	Practical chiral alcohol manufacture using ketoreductases Gjalt W. Huisman, Jack Liang, Anke Krebber · Current Opinion in Chemical Biology Review	13 Jan 2010	403
15	Genome shuffling of Lactobacillus for improved acid tolerance Ranjan Patnaik, Susan Louie, Vesna Gavrilovic et al. · Nature Biotechnology	Jul 2002	383
16	Large-Scale Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes Hila Sberro, Brayon J. Fremin, Soumaya Zlitni et al. · Cell Open access	Aug 2019	260
17	Formal Asymmetric Biocatalytic Reductive Amination Dominik Koszelewski, Iván Lavandera, Dorina Clay et al. · Angewandte Chemie International Edition	29 Oct 2008	240
18	Development of a Biocatalytic Process as an Alternative to the (−)-DIP-Cl-Mediated Asymmetric Reduction of a Key Intermediate of Montelukast Jack Liang, James Joseph Lalonde, Birthe Borup et al. · Organic Process Research & Development	3 Dec 2009	233
19	The role of distant mutations and allosteric regulation on LovD active site dynamics Gonzalo Jiménez‐Osés, Sílvia Osuna, Xue Gao et al. · Nature Chemical Biology Open access	13 Apr 2014	224
20	Efficient, Chemoenzymatic Process for Manufacture of the Boceprevir Bicyclic [3.1.0]Proline Intermediate Based on Amine Oxidase-Catalyzed Desymmetrization Tao Li, Jack Liang, Alexandre Ambrogelly et al. · Journal of the American Chemical Society	12 Mar 2012	218
21	Directed evolution of an ultrastable carbonic anhydrase for highly efficient carbon capture from flue gas Oscar Alvizo, Luan J. Nguyen, Christopher K. Savile et al. · Proceedings of the National Academy of Sciences Open access	3 Nov 2014	210
22	On the development of new biocatalytic processes for practical pharmaceutical synthesis Gjalt W. Huisman, Steven J. Collier · Current Opinion in Chemical Biology Review	22 Feb 2013	201
23	Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19 John A. McIntosh et al. · ACS Central Science Open access	29 Oct 2021	199
24	APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function Monica Xiong, Hong Jiang, Javier Remolina Serrano et al. · Science Translational Medicine Open access	17 Feb 2021	198
25	Asymmetric Synthesis of Optically Pure Pharmacologically Relevant Amines Employing ω‐Transaminases Dominik Koszelewski, Iván Lavandera, Dorina Clay et al. · Advanced Synthesis & Catalysis	17 Nov 2008	195
26	Biotechnology for the acceleration of carbon dioxide capture and sequestration Christopher K. Savile, James Joseph Lalonde · Current Opinion in Biotechnology Review	7 Jul 2011	190
27	Rapid cloning of rearranged immunoglobulin genes from human hybridoma cells using mixed primers and the polymerase chain reaction James W. Larrick, Lena Danielsson, Carol A. Brenner et al. · Biochemical and Biophysical Research Communications	May 1989	171
28	Native interleukin 1 inhibitors James W. Larrick · Immunology Today	Feb 1989	164
29	Hepatitis C virus antigen in hepatocytes: Immunomorphologic detection and identification K. Krawczyński, Michael J. Beach, Daniel W. Bradley et al. · Gastroenterology	Aug 1992	154
30	MinION™ nanopore sequencing of environmental metagenomes: a synthetic approach Bonnie L. Brown, Mick Watson, Samuel S. Minot et al. · GigaScience Open access	24 Feb 2017	150
31	Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery Gabriel J. Brighty, Rachel C. Botham, Suhua Li et al. · Nature Chemistry Open access	31 Aug 2020	145
32	A kinase-cGAS cascade to synthesize a therapeutic STING activator John A. McIntosh et al. · Nature	16 Mar 2022	144
33	Colonization of the live biotherapeutic product VE303 and modulation of the microbiota and metabolites in healthy volunteers Melissa Dsouza et al. · Cell Host & Microbe Open access	Apr 2022	135
34	Enabling Biological Nitrogen Fixation for Cereal Crops in Fertilized Fields Amy Wen et al. · ACS Synthetic Biology Open access	Dec 2021	134
35	Highly Enantioselective Reduction of a Small Heterocyclic Ketone: Biocatalytic Reduction of Tetrahydrothiophene-3-one to the Corresponding (R)-Alcohol Jack Liang, Emily C. Mundorff, Rama Voladri et al. · Organic Process Research & Development	Dec 2009	132
36	Complementary DNA sequence of rabbit CAP18—A unique lipopolysaccharide binding protein James W. Larrick, John G. Morgan, Ilona Palings et al. · Biochemical and Biophysical Research Communications	Aug 1991	128
37	Global kinetic analysis of proteolysis via quantitative targeted proteomics Nicholas J. Agard, Sami Mahrus, Jonathan C. Trinidad et al. · Proceedings of the National Academy of Sciences Open access	23 Jan 2012	123
38	Deracemisation of α‐Chiral Primary Amines by a One‐Pot, Two‐Step Cascade Reaction Catalysed by ω‐Transaminases Dominik Koszelewski, Dorina Clay, David Rozzell et al. · European Journal of Organic Chemistry	Apr 2009	123
39	Accelerating Biocatalysis Discovery with Machine Learning: A Paradigm Shift in Enzyme Engineering, Discovery, and Design Braun Markus, Gruber Christian C, Krassnigg Andreas et al. · ACS Catalysis Open access	26 Oct 2023	110
40	Enzyme optimization: moving from blind evolution to statistical exploration of sequence–function space Richard J. Fox, Gjalt W. Huisman · Trends in biotechnology Review	30 Jan 2008	103
41	Engineering an Amine Transaminase for the Efficient Production of a Chiral Sacubitril Precursor Scott J. Novick, Nikki Dellas, Ravi Garcia et al. · ACS Catalysis Open access	10 Mar 2021	95
42	A two-sample Bayesian t-test for microarray data Richard J. Fox, Matthew W. Dimmic · BMC Bioinformatics Open access	10 Mar 2006	93
43	Old Yellow Enzyme‐Catalyzed Dehydrogenation of Saturated Ketones Matthias Schittmayer, Anton Glieder, Michael K. Uhl et al. · Advanced Synthesis & Catalysis	9 Feb 2011	90
44	Enzyme evolution for industrial biocatalytic cascades Jovana Nazor, Joyce F. Liu, Gjalt W. Huisman · Current Opinion in Biotechnology Review	28 Jan 2021	87
45	Engineering biosynthetic enzymes for industrial natural product synthesis Stephanie S. Galanie, David A. Entwistle, James Joseph Lalonde · Natural Product Reports Open access	2020	86
46	Baeyer–Villiger Monooxygenase-Mediated Synthesis of Esomeprazole As an Alternative for Kagan Sulfoxidation Yong Koy Bong, Shiwei Song, Jovana Nazor et al. · The Journal of Organic Chemistry	22 Jun 2018	80
47	Coset codes for partial response channels; or, coset codes with spectral nulls G. David Forney, A.R. Calderbank · IEEE Transactions on Information Theory	1989	80
48	Telomeric structure in cells with chromosome end associations David L. Saltman, Rodman Morgan, Michael L. Cleary et al. · Chromosoma	1993	80
49	Molecular organization and replication of hepatitis E virus (HEV) Gregory R. Reyes, Cecilia Huang, Albert W. Tam et al. · Archives of virology. Supplementum Book chapter	1993	79
50	Multicast and broadcast services in a knockout packet switch Kai Y. Eng, Michael G. Hluchyj, Y. S. Yeh Conference paper	6 Jan 2003	79

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.