Institution · Cold Spring Harbor Laboratory
Most cited papers from Cold Spring Harbor Laboratory
What are the most cited papers from Cold Spring Harbor Laboratory?
The most cited paper from Cold Spring Harbor Laboratory is "STAR: ultrafast universal RNA-seq aligner" (Alexander Yu. Dobin, Carrie Davis, Felix Schlesinger et al., 2012), with 58,026 citations. Next come "Initial sequencing and analysis of the human genome" (24,745) and "A global reference for human genetic variation" (20,444).
Showing 50 of 60 papers. Every paper with more than 2,455 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | STAR: ultrafast universal RNA-seq aligner Alexander Yu. Dobin, Carrie Davis, Felix Schlesinger et al. · Bioinformatics | 25 Oct 2012 | 58,026 |
| 2 | Initial sequencing and analysis of the human genome Eric S. Lander et al. · Nature | Feb 2001 | 24,745 |
| 3 | A global reference for human genetic variation Corresponding authors et al. · Nature | 29 Sep 2015 | 20,444 |
| 4 | An integrated encyclopedia of DNA elements in the human genome Ian Dunham et al. · Nature | Sep 2012 | 19,751 |
| 5 | Studies on transformation of Escherichia coli with plasmids Douglas Hanahan · Journal of Molecular Biology | Jun 1983 | 11,339 |
| 6 | An integrated map of genetic variation from 1,092 human genomes Gil A. McVean et al. · Nature | 31 Oct 2012 | 8,281 |
| 7 | A plant DNA minipreparation: Version II Stephen L. Dellaporta, Jonathan M. D. Wood, James B Hicks · Plant Molecular Biology Reporter | Sep 1983 | 7,616 |
| 8 | Network Motifs: Simple Building Blocks of Complex Networks Ron Milo, Shai S. Shen-Orr, Shalev Itzkovitz et al. · Science | 24 Oct 2002 | 7,594 |
| 9 | The biochemistry of apoptosis Michael Otmar Hengartner · Nature | Oct 2000 | 7,357 |
| 10 | Initial sequencing and comparative analysis of the mouse genome Asif T. Chinwalla et al. · Nature | Dec 2002 | 7,343 |
| 11 | Integrative analysis of 111 reference human epigenomes Anshul Kundaje et al. · Nature | 17 Feb 2015 | 7,245 |
| 12 | MicroRNAs: small RNAs with a big role in gene regulation Lin He, Gregory James Hannon · Nature Reviews Genetics | 21 Jun 2004 | 7,124 |
| 13 | Caspases: Enemies Within Nancy A. Thornberry, Yuri A. Lazebnik · Science | 28 Aug 1998 | 6,945 |
| 14 | Understanding the tumor immune microenvironment (TIME) for effective therapy Mikhail Binnewies, Edward W. Roberts, Kelly Kersten et al. · Nature Medicine | 20 Apr 2018 | 6,338 |
| 15 | The Immune Landscape of Cancer Vésteinn Thórsson et al. · Immunity | Apr 2018 | 6,328 |
| 16 | The International HapMap Project Richard A. Gibbs et al. · Nature | 18 Dec 2003 | 6,187 |
| 17 | The Reactome pathway Knowledgebase Antonio Fabregat et al. · Nucleic Acids Research | 9 Dec 2015 | 6,015 |
| 18 | Telomeres shorten during ageing of human fibroblasts Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature | May 1990 | 5,775 |
| 19 | Landscape of transcription in human cells Sarah Djebali et al. · Nature | Sep 2012 | 5,447 |
| 20 | The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression Thomas Derrien et al. · Genome Research | Sep 2012 | 5,308 |
| 21 | Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell | Mar 1997 | 5,154 |
| 22 | Role for a bidentate ribonuclease in the initiation step of RNA interference Emily Bernstein, Amy A. Caudy, Scott M. Hammond et al. · Nature | 2001 | 4,947 |
| 23 | PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer Jing Li, Clifford Yen, Danny Liaw et al. · Science | 28 Mar 1997 | 4,843 |
| 24 | Comprehensive Identification of Cell Cycle–regulated Genes of the YeastSaccharomyces cerevisiaeby Microarray Hybridization Paul T. Spellman, Gavin J. Sherlock, Michael Q. Zhang et al. · Molecular Biology of the Cell | Dec 1998 | 4,810 |
| 25 | A second generation human haplotype map of over 3.1 million SNPs Sarah Shaw Murray et al. · Nature | Oct 2007 | 4,615 |
| 26 | Coming of age: ten years of next-generation sequencing technologies Sara Goodwin, John D. McPherson, William Richard McCombie · Nature Reviews Genetics | 17 May 2016 | 4,586 |
| 27 | The B73 Maize Genome: Complexity, Diversity, and Dynamics Patrick S. Schnable et al. · Science | 20 Nov 2009 | 4,265 |
| 28 | Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature | Jul 1995 | 4,026 |
| 29 | A framework for advancing our understanding of cancer-associated fibroblasts Erik A. Sahai et al. · Nature reviews. Cancer | 24 Jan 2020 | 3,962 |
| 30 | A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 Manuel Serrano, Gregory James Hannon, David Beach · Nature | Dec 1993 | 3,697 |
| 31 | RNA interference Gregory James Hannon · Nature | Jul 2002 | 3,554 |
| 32 | A microRNA polycistron as a potential human oncogene Lin He, J. Michael Thomson, Michael T. Hemann et al. · Nature | Jun 2005 | 3,508 |
| 33 | The tomato genome sequence provides insights into fleshy fruit evolution Hideki Hirakawa et al. · Nature | May 2012 | 3,442 |
| 34 | Mesenchymal and haematopoietic stem cells form a unique bone marrow niche Simón Méndez‐Ferrer, Tatyana V. Michurina, Francesca Ferraro et al. · Nature | Aug 2010 | 3,419 |
| 35 | p21 is a universal inhibitor of cyclin kinases Yue Xiong, Gregory James Hannon, Hui Zhang et al. · Nature | Dec 1993 | 3,400 |
| 36 | The Sorghum bicolor genome and the diversification of grasses Andrew H. Paterson et al. · Nature | 2009 | 3,257 |
| 37 | Interneurons of the neocortical inhibitory system Henry Markram, Maria Toledo‐Rodriguez, Yun Wang et al. · Nature reviews. Neuroscience | 20 Sep 2004 | 3,086 |
| 38 | The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product Nicholas J. Dyson, Peter M. Howley, Karl Münger et al. · Science | 17 Feb 1989 | 3,072 |
| 39 | An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells Scott M. Hammond, Emily Bernstein, David Beach et al. · Nature | Mar 2000 | 3,024 |
| 40 | A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms The International SNP Map Working Group et al. · Nature | 15 Feb 2001 | 2,998 |
| 41 | RASTtk: A modular and extensible implementation of the RAST algorithm for building custom annotation pipelines and annotating batches of genomes Thomas Scott Brettin, James J. Davis, Terry L. Disz et al. · Scientific Reports | 10 Feb 2015 | 2,975 |
| 42 | GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes T. Rhyker Ranallo-Benavidez, Kamil S. Jaroň, Michael C. Schatz · Nature Communications | 18 Mar 2020 | 2,945 |
| 43 | BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc Jake E. Delmore et al. · Cell | Sep 2011 | 2,889 |
| 44 | Strong Association of De Novo Copy Number Mutations with Autism Jonathan L. Sebat et al. · Science | 15 Mar 2007 | 2,862 |
| 45 | The contribution of de novo coding mutations to autism spectrum disorder Ivan Iossifov et al. · Nature | 29 Oct 2014 | 2,836 |
| 46 | Processing of primary microRNAs by the Microprocessor complex Ahmet M. Denli, Bastiaan B.J. Tops, Ronald H.A. Plasterk et al. · Nature | Nov 2004 | 2,784 |
| 47 | Tumour evolution inferred by single-cell sequencing Nicholas E. Navin, Jude Kendall, Jennifer E. Troge et al. · Nature | 13 Mar 2011 | 2,755 |
| 48 | Argonaute2 Is the Catalytic Engine of Mammalian RNAi Jidong Liu, Michelle A. Carmell, Fabiola V. Rivas et al. · Science | 29 Jul 2004 | 2,750 |
| 49 | A microRNA component of the p53 tumour suppressor network Lin He, Xingyue He, Lee P. Lim et al. · Nature | 6 Jun 2007 | 2,713 |
| 50 | The Significance of Responses of the Genome to Challenge Barbara McClintock · Science | 16 Nov 1984 | 2,698 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.