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Nonprofit · Cold Spring Harbor · United States

Cold Spring Harbor Laboratory

In research, Cold Spring Harbor Laboratory stands highest in Life Sciences (#676 of 7,800 worldwide), Biochemistry, Genetics and Molecular Biology (#854 of 3,579 worldwide) and Molecular Biology (#611 of 2,175 worldwide), 2022–2025. Relative to its size it is most specialised in Molecular Biology and Biochemistry, Genetics and Molecular Biology — Molecular Biology is 9.9× its share of world research.

cshl.eduROR OpenAlex
World rank, 2022–2025
#2,038
of 28,054 · #446 all time
Rank in United States
#313
of 4,192
Research works
4.6k
▼ 13% vs 2013–17
Citations
666k
143.3 per fractional work
Top-10% rate
31.0%
record average 16.5%
Open access
56%
world 28%

What is Cold Spring Harbor Laboratory known for in research?

The fields where it stands highest, 2022–2025, ranked among every institution above the floor in each field.

FieldWorld rankWhere that sitsTop-10% rateWorksAll time
Life SciencesDomain #676 of 7,800 33.6%226 #100
Biochemistry, Genetics and Molecular BiologyField #854 of 3,579 30.6%152 #77
Molecular BiologySubfield #611 of 2,175 32.7%101 #36
MedicineField #4,993 of 10,443 22.6%63 #954
Health SciencesDomain #6,329 of 11,982 23.3%66 #1281

Each strip is that field’s whole ranked pool, with the notch where Cold Spring Harbor Laboratory sits in it, in the colour of the band that rank falls in. The track under the rate is the rate itself: it carries no world mark, because the world rate differs by field (from about 6% to 21% in this record).

Which of those standings moved

The same fields on both windows: where it stood over the whole record, and where it stands in 2022–2025. The distance is the story, and it is the one thing the two rank columns above cannot show.

  1. Life Sciences#100 #676
  2. Biochemistry, Genetics and Molecular Biology#77 #854
  3. Molecular Biology#36 #611
  4. Medicine#954 #4,993
  5. Health Sciences#1,281 #6,329
all time2022–2025, better2022–2025, worse

A dot further right is a better standing. Fields it was not ranked in over the whole record are left out.

What does Cold Spring Harbor Laboratory specialise in?

Where its research is concentrated relative to its size: Molecular Biology takes 9.9× the share of its output that it takes of world research.

  1. Molecular BiologySubfield · 101.3 works9.9×
  2. Biochemistry, Genetics and Molecular BiologyField · 152.1 works8.4×
← less than its size predicts1×more →

Location quotient, a volume reading rather than an impact one. It surfaces small, lopsided specialities.

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 1.41× its world share, 23 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 8.45× its world share, 152 worksBiochemistry, Geneti…Immunology and Microbiology: 3.46× its world share, 12 worksImmunology and Micro…Neuroscience: 6.97× its world share, 38 worksNeurosciencePharmacology, Toxicology and Pharmaceutics: 0.82× its world share, 1 worksPharmacology, Toxico…Chemistry: 0.91× its world share, 5 worksChemistryComputer Science: 0.32× its world share, 8 worksComputer ScienceEarth and Planetary Sciences: 0.15× its world share, 1 worksEarth and Planetary …Energy: 0.02× its world share, 0 worksEnergyEngineering: 0.14× its world share, 7 worksEngineeringEnvironmental Science: 0.34× its world share, 6 worksEnvironmental ScienceMaterials Science: 0.11× its world share, 1 worksMaterials ScienceMathematics: 0.03× its world share, 0 worksMathematicsPhysics and Astronomy: 0.17× its world share, 1 worksPhysics and AstronomyHealth Professions: 0.04× its world share, 0 worksHealth ProfessionsMedicine: 0.98× its world share, 63 worksMedicineNursing: 1.23× its world share, 2 worksNursingVeterinary: 0.05× its world share, 0 worksVeterinaryArts and Humanities: 0.21× its world share, 2 worksArts and HumanitiesDecision Sciences: 1.24× its world share, 4 worksDecision SciencesEconomics, Econometrics and Finance: 0.05× its world share, 0 worksEconomics, Econometr…Psychology: 0.68× its world share, 7 worksPsychologySocial Sciences: 0.08× its world share, 3 worksSocial Sciences1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Biochemistry, Genetics and Molecular Biology, 8.4×. Every wedge is a field page.

Who are the top researchers at Cold Spring Harbor Laboratory?

Ranked on the composite score, David A. Tuveson, Michael Wigler and Bruce Stillman lead among researchers whose main affiliation is Cold Spring Harbor Laboratory.

  1. 1 David A. Tuveson United States · #9,172 worldwide 1.2k citations · 92 works
  2. 2 Michael Wigler United States · #10,499 worldwide 1.4k citations · 49 works
  3. 3 Bruce Stillman United States · #11,322 worldwide 775 citations · 56 works
  4. 4 T Gingeras United States · #22,577 worldwide 1.7k citations · 37 works
  5. 5 Gregory J. Hannon United States · #24,372 worldwide 1.5k citations · 36 works
  6. 6 W. Richard McCombie United States · #31,722 worldwide 945 citations · 34 works
  7. 7 James Hicks United States · #36,158 worldwide 486 citations · 47 works
  8. 8 Nicholas K. Tonks United States · #42,295 worldwide 467 citations · 37 works
  9. 9 Jeffrey N. Strathern United States · #43,516 worldwide 429 citations · 39 works
  10. 10 Robert A. Martienssen United States · #46,716 worldwide 614 citations · 30 works
All ranked researchers at Cold Spring Harbor Laboratory

Which keywords describe research at Cold Spring Harbor Laboratory?

By fractional works in 2022–2025, weighted toward what it does more of than the world: Gene Expression, Cancer, Epigenetic Regulation, Tumor Microenvironment, Transcription Factors, Immunotherapy, RNA-Seq and Metabolism.

▲ more of its work than of the world’s◆ about the world’s share▼ less than the world’s

Size is fractional works in 2022–2025 in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Cancer27▲ 5.9×37 topics
  2. Gene Expression25▲ 12×18 topics
  3. Inflammation16▲ 2.2×41 topics
  4. Epigenetic Regulation14▲ 20×6 topics
  5. Immunotherapy14▲ 5.9×14 topics
  6. Tumor Microenvironment14▲ 9.6×7 topics
  7. Transcription Factors13▲ 31×5 topics
  8. RNA-Seq11▲ 31×2 topics
  9. Metabolism10▲ 6.1×10 topics
  10. Neurological Disorders10▲ 5.2×10 topics
  11. Chemotherapy9▲ 3.8×11 topics
  12. Genomic Instability9▲ 24×2 topics
  13. Gene Regulation9▲ 29×5 topics
  14. Chromatin8▲ 52×2 topics
  15. Neuronal Circuits8▲ 31×2 topics
  16. Transcriptional Regulation8▲ 15×9 topics
  17. Neurobiology8▲ 8.9×5 topics
  18. Phylogenetic Analysis8▲ 7.6×4 topics
  19. Cancer Progression8▲ 12×6 topics
  20. Synaptic Plasticity8▲ 10×5 topics
  21. Targeted Therapy8▲ 9.9×4 topics
  22. Alternative Splicing7▲ 42×1 topic
  23. RNA-Binding Proteins7▲ 42×1 topic
  24. Genetic Code7▲ 30×2 topics
  25. Translation7▲ 12×2 topics
  26. Epigenetics7▲ 50×3 topics
  27. Dendritic Spines7▲ 26×2 topics
  28. Cell-Free DNA7▲ 20×2 topics
  29. Gene Expression Regulation7▲ 19×3 topics
  30. RNA Structure7▲ 37×1 topic
  31. Ribosome7▲ 37×1 topic
  32. Drug Discovery7▲ 8.8×6 topics
  33. MicroRNA7▲ 16×2 topics
  34. Cancer Genomics7▲ 27×1 topic
  35. Mutational Signatures7▲ 27×1 topic
  36. Functional Genomics6▲ 24×2 topics
  37. GABAergic6▲ 38×1 topic
  38. Neurotransmission6▲ 38×1 topic
  39. RNA methylation6▲ 22×1 topic
  40. m6A-seq6▲ 22×1 topic

Which research topics does Cold Spring Harbor Laboratory publish most on?

By volume in 2022–2025: RNA Research and Splicing, RNA and protein synthesis mechanisms, Cancer Genomics and Diagnostics and Neuroscience and Neuropharmacology Research.

RNA Research and Splicing7RNA Research and Splicing: 7 fractional worksRNA and protein synthesi…7RNA and protein synthesis mechanisms: 7 fractional worksCancer Genomics and Diagnostics: 7 fractional worksNeuroscience and Neuroph…6Neuroscience and Neuropharmacology Research: 6 fractional worksRNA modifications and ca…6RNA modifications and cancer: 6 fractional worksGenomics and Phylogenetic Studies: 6 fractional worksGenomics and Chromatin Dynamics: 6 fractional worksPlant Molecular Biology …6Plant Molecular Biology Research: 6 fractional worksNeural dynamics and brain function: 5 fractional worksCancer Cells and Metastasis: 5 fractional works
Molecular BiologyCancer ResearchCellular and Molecular NeurosciencePlant Science2 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 RNA Research and Splicing Molecular Biology 7 works
  2. 2 RNA and protein synthesis mechanisms Molecular Biology 7 works
  3. 3 Cancer Genomics and Diagnostics Cancer Research 7 works
  4. 4 Neuroscience and Neuropharmacology Research Cellular and Molecular Neuroscience 6 works
  5. 5 RNA modifications and cancer Molecular Biology 6 works
  6. 6 Genomics and Phylogenetic Studies Molecular Biology 6 works
  7. 7 Genomics and Chromatin Dynamics Molecular Biology 6 works
  8. 8 Plant Molecular Biology Research Plant Science 6 works
  9. 9 Neural dynamics and brain function Cognitive Neuroscience 5 works
  10. 10 Cancer Cells and Metastasis Oncology 5 works

How open and international is its research?

Against the world’s own shares — the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available55.8%not open44.2%

World: 28% of research is openly available.

with international co-authors16.8%domestic only83.2%

World: 19% is written across borders.

How has Cold Spring Harbor Laboratory's research output changed?

Output in 2018–2022 was 13% lower than in 2013–2017.

1990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Other research institutions in Cold Spring Harbor

All research institutions in Cold Spring Harbor

Research measures only: rankings here say nothing about teaching, admissions or student experience. Comparable institutions and collaboration partners are in the interactive view on the map.