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Topic · Molecular Biology

RNA Research and Splicing

RNA Research and Splicing is a research topic within Molecular Biology. Science Explorer counts 71k research works in it since 1950. 9.7% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the regulation of RNA processing and function, including topics such as alternative splicing, RNA-binding proteins, phase separation, mRNA decay, stress granules, transcriptome analysis, exon junctions, polyadenylation, nonsense-mediated decay, and RNA phase transitions.

  • Alternative Splicing
  • RNA-Binding Proteins
  • Phase Separation
  • mRNA Decay
  • Stress Granules
  • Transcriptome
  • Exon Junctions
  • Polyadenylation
  • Nonsense-Mediated Decay
  • RNA Phase Transitions
Research works
71k
fractional, since 1950
In the world top 10%
6.9k
per year above
Top-10% rate
9.7%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-3%
the tick is no change
Largest producer
China
36% of the 10 largest, 2022-now
RNA Research and Splicing

Which countries lead RNA Research and Splicing research?

By volume, China and the United States publish the most (3.7k and 3.4k works in 2022-now).

By volume, 2022-now

  1. 1 China 3.7k works
  2. 2 United States 3.4k works
  3. 3 Germany 589 works
  4. 4 Japan 530 works
  5. 5 United Kingdom 436 works
  6. 6 France 369 works
  7. 7 India 365 works
  8. 8 Canada 278 works
  9. 9 Italy 272 works
  10. 10 Spain 226 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 36.2%United States: 33.5%Germany: 5.8%Japan: 5.2%6 others listed: 19.3%36%largest
China3,652 · 36.2%United States3,382 · 33.5%Germany589 · 5.8%Japan530 · 5.2%6 others listed1,947 · 19.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead RNA Research and Splicing research?

By volume in 2022-now, Chinese Academy of Sciences publishes the most RNA Research and Splicing research, followed by Centre National de la Recherche Scientifique and Harvard University.

By volume, 2022-now

  1. 1 Chinese Academy of SciencesChina 146 works
  2. 2 Centre National de la Recherche ScientifiqueFrance 139 works
  3. 3 Harvard UniversityUnited States 135 works
  4. 4 National Institutes of HealthUnited States 132 works
  5. 5 Sun Yat-sen UniversityChina 113 works
  6. 6 Russian Academy of SciencesRussia 112 works
  7. 7 Shanghai Jiao Tong UniversityChina 97 works
  8. 8 Zhejiang UniversityChina 81 works
  9. 9 Peking UniversityChina 74 works
  10. 10 Max Planck SocietyGermany 71 works

Who are the leading researchers in RNA Research and Splicing?

The most-cited researchers publishing on RNA Research and Splicing include Eric S. Lander, Rob Knight and George Davey Smith.

  1. 1 Eric S. Lander United States 524k citations
  2. 2 Rob Knight United States 468k citations
  3. 3 George Davey Smith United Kingdom 435k citations
  4. 4 Richard M. Durbin United Kingdom 410k citations
  5. 5 Mark J. Daly United States 403k citations
  6. 6 Stacey L. Gabriel United States 402k citations
  7. 7 Peer Bork Germany 396k citations
  8. 8 Robert John Tibshirani United States 396k citations
  9. 9 Guido Kroemer France 386k citations
  10. 10 Bert Vogelstein United States 373k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in RNA Research and Splicing?

The most cited paper in RNA Research and Splicing is "Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method" (Kenneth J. Livak, Thomas D. Schmittgen, 2001), with 184,956 citations. Next come "Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2" (104,335) and "STAR: ultrafast universal RNA-seq aligner" (58,026).

Most cited papers
#PaperReleasedCitations
1 Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method Kenneth J. Livak, Thomas D. Schmittgen · Methods Dec 2001 184,956
2 Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 Michael I. Love, Wolfgang K. Huber, Simon Anders · Genome biology Open access 5 Dec 2014 104,335
3 STAR: ultrafast universal RNA-seq aligner Alexander Yu. Dobin, Carrie Davis, Felix Schlesinger et al. · Bioinformatics Open access 25 Oct 2012 58,026
4 limma powers differential expression analyses for RNA-sequencing and microarray studies Matthew E. Ritchie, Belinda Phipson, Di Wu et al. · Nucleic Acids Research Open access 20 Jan 2015 44,530
5 Analyzing real-time PCR data by the comparative CT method Thomas D. Schmittgen, Kenneth J. Livak · Nature Protocols Jun 2008 27,138
All 100 most cited papers, with filters and sorting

Where is RNA Research and Splicing research done?

The largest centres of RNA Research and Splicing research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Paris (France). Among places with at least 20 works in it, it is an unusually large share of all research in Chevy Chase, Rehovot and Bethesda.

Largest cities, 2022-now

  1. 1 BeijingChina 457 works
  2. 2 ShanghaiChina 318 works
  3. 3 GuangzhouChina 258 works
  4. 4 ParisFrance 180 works
  5. 5 WuhanChina 180 works
  6. 6 New YorkUnited States 171 works
  7. 7 NanjingChina 151 works
  8. 8 TokyoJapan 146 works
  9. 9 HangzhouChina 145 works
  10. 10 CambridgeUnited States 134 works

Where it is the local speciality

  1. Chevy ChaseUS · 48.5 works45×
  2. RehovotIL · 25.1 works14×
  3. BethesdaUS · 115.9 works8.2×
← less than its size predicts1×more →

Location quotient: how much more of its research is in RNA Research and Splicing than the world average.

See RNA Research and Splicing on the map

Where is the best place to study RNA Research and Splicing?

Among universities, judged by research, Harvard University, Massachusetts Institute of Technology and Max Planck Institute for Multidisciplinary Sciences score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 18.67%fractional works in this field (log) →share of work in the world top 10% →Max Planck Institute…Princeton UniversityMassachusetts Instit…Harvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 69.116.3%4.0×135 -9.2%
2Massachusetts Institute of TechnologyUnited States 67.817.5%5.6×41 +13.4%
3Max Planck Institute for Multidisciplinary Sciences 63.529.7%63.3×11 -
4Princeton UniversityUnited States 62.018.2%7.3×34 +42.1%
5Sun Yat-sen UniversityChina 61.915.1%5.2×113 +5.3%
6ETH ZurichSwitzerland 60.319.1%3.6×26 +26.6%
7Rockefeller UniversityUnited States 57.926.0%27.9×18 -1.7%
8Johns Hopkins UniversityUnited States 57.612.9%4.1×66 +6.2%
9University of California San DiegoUnited States 57.613.2%5.7×58 +4.5%
10Stanford UniversityUnited States 56.418.7%3.2×49 -12.9%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in RNA Research and Splicing, country by country

Is RNA Research and Splicing research growing?

Output in 2022-2025 was 3% lower than in 2018-2021, peaking in 2021.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is RNA Research and Splicing as a percentage of every work published that year, 0.050% in 2024.

still counting0.050%0.10%RNA Research and Splicing0.045% in 202519801990200020102020

Fractional works of RNA Research and Splicing over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%RNA Research and Splicing9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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