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Topic · Cancer Research

Cancer Genomics and Diagnostics

Cancer Genomics and Diagnostics is a research topic within Cancer Research. Science Explorer counts 60k research works in it since 1950. 10.2% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the genomic landscape of cancer, mutational signatures, intratumor heterogeneity, liquid biopsies, somatic mutations, tumor evolution, cell-free DNA, genomic instability, targeted therapy, and clonal evolution in various cancer types.

  • Cancer Genomics
  • Mutational Signatures
  • Intratumor Heterogeneity
  • Liquid Biopsies
  • Somatic Mutations
  • Tumor Evolution
  • Cell-Free DNA
  • Genomic Instability
  • Targeted Therapy
  • Clonal Evolution
Research works
60k
fractional, since 1950
In the world top 10%
6.2k
per year above
Top-10% rate
10.2%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+9%
the tick is no change
Largest producer
United States
45% of the 10 largest, 2022-now
Cancer Genomics and Diagnostics

Which countries lead Cancer Genomics and Diagnostics research?

By volume, the United States and China publish the most (6.2k and 2.6k works in 2022-now).

By volume, 2022-now

  1. 1 United States 6.2k works
  2. 2 China 2.6k works
  3. 3 United Kingdom 777 works
  4. 4 Germany 732 works
  5. 5 Italy 698 works
  6. 6 Japan 686 works
  7. 7 India 597 works
  8. 8 France 500 works
  9. 9 Canada 470 works
  10. 10 Spain 452 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 45.2%China: 18.9%United Kingdom: 5.7%Germany: 5.3%6 others listed: 24.8%45%largest
United States6,198 · 45.2%China2,594 · 18.9%United Kingdom777 · 5.7%Germany732 · 5.3%6 others listed3,403 · 24.8%

Shares of the rows listed above, not of the whole node.

Which institutions lead Cancer Genomics and Diagnostics research?

By volume in 2022-now, Harvard University publishes the most Cancer Genomics and Diagnostics research, followed by The University of Texas MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center.

By volume, 2022-now

  1. 1 Harvard UniversityUnited States 357 works
  2. 2 The University of Texas MD Anderson Cancer CenterUnited States 227 works
  3. 3 Memorial Sloan Kettering Cancer CenterUnited States 160 works
  4. 4 National Institutes of HealthUnited States 152 works
  5. 5 Sun Yat-sen UniversityChina 127 works
  6. 6 Mayo ClinicUnited States 122 works
  7. 7 University of TorontoCanada 112 works
  8. 8 Johns Hopkins UniversityUnited States 104 works
  9. 9 Cornell UniversityUnited States 101 works
  10. 10 Stanford UniversityUnited States 101 works

Who are the leading researchers in Cancer Genomics and Diagnostics?

The most-cited researchers publishing on Cancer Genomics and Diagnostics include Ahmedin Jemal, Rebecca L. Siegel and Freddie Bray.

  1. 1 Ahmedin Jemal United States 761k citations
  2. 2 Rebecca L. Siegel United States 582k citations
  3. 3 Freddie Bray France 550k citations
  4. 4 Eric S. Lander United States 524k citations
  5. 5 Jacques Ferlay France 486k citations
  6. 6 Rob Knight United States 468k citations
  7. 7 Ali H. Mokdad United States 429k citations
  8. 8 Walter Churchill Willett United States 411k citations
  9. 9 Richard M. Durbin United Kingdom 410k citations
  10. 10 Mark J. Daly United States 403k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Cancer Genomics and Diagnostics?

The most cited paper in Cancer Genomics and Diagnostics is "Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology" (Sue M. Richards, Nazneen Aziz, Sherri J. Bale et al., 2015), with 33,443 citations. Next come "Cancer statistics, 2020" (21,499) and "The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data" (18,789).

Most cited papers
#PaperReleasedCitations
1 Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology Sue M. Richards, Nazneen Aziz, Sherri J. Bale et al. · Genetics in Medicine Open access 5 Mar 2015 33,443
2 Cancer statistics, 2020 Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians Open access 2020 21,499
3 The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data Ethan G Cerami, Jianjiong Gao, Uğur Doğrusöz et al. · Cancer Discovery Open access May 2012 18,789
4 Cancer Statistics, 2021 Rebecca L. Siegel, Kimberly D. Miller, Hannah E. Fuchs et al. · CA A Cancer Journal for Clinicians Open access 2021 17,460
5 Integrative genomics viewer James Theodore Robinson, Helga Thorvaldsdóttir, Wendy Winckler et al. · Nature Biotechnology Open access 2011 16,977
All 100 most cited papers, with filters and sorting

Where is Cancer Genomics and Diagnostics research done?

The largest centres of Cancer Genomics and Diagnostics research in 2022-now are New York (United States), Beijing (China), Houston (United States) and Shanghai (China). Among places with at least 20 works in it, it is an unusually large share of all research in Cambridge, San Carlos and Redwood City.

Largest cities, 2022-now

  1. 1 New YorkUnited States 445 works
  2. 2 BeijingChina 395 works
  3. 3 HoustonUnited States 320 works
  4. 4 ShanghaiChina 304 works
  5. 5 LondonUnited Kingdom 283 works
  6. 6 BostonUnited States 279 works
  7. 7 SeoulSouth Korea 265 works
  8. 8 GuangzhouChina 241 works
  9. 9 TorontoCanada 198 works
  10. 10 TokyoJapan 195 works

Where it is the local speciality

  1. Cambridge26.6 works123×
  2. San CarlosUS · 31.7 works114×
  3. Redwood CityUS · 55.2 works46×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Cancer Genomics and Diagnostics than the world average.

See Cancer Genomics and Diagnostics on the map

Where is the best place to study Cancer Genomics and Diagnostics?

Among universities, judged by research, Harvard University, Kettering University and Oncode Institute score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 16.94%fractional works in this field (log) →share of work in the world top 10% →Chinese University o…Kettering UniversityOncode InstituteHarvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 75.017.3%7.5×357 -12.8%
2Kettering UniversityUnited States 74.021.1%59.8×32 +103.0%
3Oncode InstituteNetherlands 63.620.3%34.2×14 +17.4%
4Chinese University of Hong KongChina 63.122.6%2.6×29 -15.5%
5Stanford UniversityUnited States 62.517.7%4.6×101 -3.2%
6University of TorontoCanada 61.810.5%3.7×112 +21.2%
7Johns Hopkins UniversityUnited States 61.413.4%4.5×104 -1.7%
8University College LondonUnited Kingdom 60.115.7%2.2×53 +30.1%
9Cornell UniversityUnited States 58.612.7%5.1×101 +3.9%
10University of CambridgeUnited Kingdom 58.618.1%2.6×47 -9.3%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Cancer Genomics and Diagnostics, country by country

Is Cancer Genomics and Diagnostics research growing?

Output in 2022-2025 was 9% higher than in 2018-2021, peaking in 2023. The fastest-growing topics are Cancer Genomics and Diagnostics.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Cancer Genomics and Diagnostics as a percentage of every work published that year, 0.071% in 2024.

still counting0.050%0.10%Cancer Genomics and Diagnostics0.064% in 202519801990200020102020

Fractional works of Cancer Genomics and Diagnostics over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Cancer Genomics and Diagnostics10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Questions people ask

Which institutions lead cancer genomics research?

By volume in 2022-now, Harvard University publishes the most Cancer Genomics and Diagnostics research, followed by The University of Texas MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center.

Which institutions lead Cancer Genomics and Diagnostics research?
All 1,273 questions in the Question Catalogue

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