Science Explorer Back to mapMap
Discussion
Topic · Cancer Research

Cancer, Lipids, and Metabolism

Cancer, Lipids, and Metabolism is a research topic within Cancer Research. Science Explorer counts 43k research works in it since 1950. 10.3% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the role of lipid metabolism, including fatty acid synthesis, cholesterol metabolism, and statin use, in the pathogenesis and progression of cancer. It discusses the metabolic reprogramming of cancer cells, the impact of specific enzymes and receptors such as Fatty Acid Synthase and CD36, and the potential therapeutic implications of targeting lipid metabolism in cancer treatment.

  • Lipid Metabolism
  • Fatty Acid Synthase
  • Cholesterol
  • Statins
  • Cancer
  • Metabolic Reprogramming
  • Lipogenesis
  • CD36 Receptor
  • HMG-CoA Reductase Inhibitors
  • Acetyl-CoA Carboxylase
Research works
43k
fractional, since 1950
In the world top 10%
4.5k
per year above
Top-10% rate
10.3%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+18%
the tick is no change
Largest producer
China
48% of the 10 largest, 2022-now
Cancer, Lipids, and Metabolism

Which countries lead Cancer, Lipids, and Metabolism research?

By volume, China and the United States publish the most (3.3k and 1.7k works in 2022-now).

By volume, 2022-now

  1. 1 China 3.3k works
  2. 2 United States 1.7k works
  3. 3 India 355 works
  4. 4 Japan 303 works
  5. 5 Italy 280 works
  6. 6 South Korea 268 works
  7. 7 Germany 207 works
  8. 8 United Kingdom 201 works
  9. 9 France 152 works
  10. 10 Iran 147 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 48.2%United States: 24.3%India: 5.1%Japan: 4.4%6 others listed: 18.1%48%largest
China3,347 · 48.2%United States1,686 · 24.3%India355 · 5.1%Japan303 · 4.4%6 others listed1,256 · 18.1%

Shares of the rows listed above, not of the whole node.

Which institutions lead Cancer, Lipids, and Metabolism research?

By volume in 2022-now, Sun Yat-sen University publishes the most Cancer, Lipids, and Metabolism research, followed by Harvard University and Nanjing Medical University.

By volume, 2022-now

  1. 1 Sun Yat-sen UniversityChina 109 works
  2. 2 Harvard UniversityUnited States 80 works
  3. 3 Nanjing Medical UniversityChina 78 works
  4. 4 Shanghai Jiao Tong UniversityChina 73 works
  5. 5 Zhejiang UniversityChina 68 works
  6. 6 Fudan UniversityChina 63 works
  7. 7 Sichuan UniversityChina 62 works
  8. 8 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 62 works
  9. 9 Capital Medical UniversityChina 59 works
  10. 10 Huazhong University of Science and TechnologyChina 57 works

Who are the leading researchers in Cancer, Lipids, and Metabolism?

The most-cited researchers publishing on Cancer, Lipids, and Metabolism include David Moher, Freddie Bray and Jacques Ferlay.

  1. 1 David Moher Canada 898k citations
  2. 2 Freddie Bray France 550k citations
  3. 3 Jacques Ferlay France 486k citations
  4. 4 George Davey Smith United Kingdom 435k citations
  5. 5 Ali H. Mokdad United States 429k citations
  6. 6 Walter Churchill Willett United States 411k citations
  7. 7 Mark J. Daly United States 403k citations
  8. 8 Stacey L. Gabriel United States 402k citations
  9. 9 Julian P. T. Higgins United Kingdom 390k citations
  10. 10 Guido Kroemer France 386k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Cancer, Lipids, and Metabolism?

The most cited paper in Cancer, Lipids, and Metabolism is "Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge" (William T. Friedewald, Robert I. Levy, Donald S. Fredrickson, 1972), with 32,670 citations. Next come "Angiogenesis in cancer and other diseases" (9,128) and "THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM" (8,822).

Most cited papers
#PaperReleasedCitations
1 Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge William T. Friedewald, Robert I. Levy, Donald S. Fredrickson · Clinical Chemistry Jun 1972 32,670
2 Angiogenesis in cancer and other diseases Peter Carmeliet, Rakesh K. Jain · Nature Sep 2000 9,128
3 THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM Richard J. Havel, Howard A. Eder, Joseph H. Bragdon · Journal of Clinical Investigation Open access Sep 1955 8,822
4 Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease Brent R. Stockwell et al. · Cell Open access Oct 2017 7,867
5 Regulation of Ferroptotic Cancer Cell Death by GPX4 Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell Open access 2014 7,814
All 100 most cited papers, with filters and sorting

Where is Cancer, Lipids, and Metabolism research done?

The largest centres of Cancer, Lipids, and Metabolism research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Nantong and Hengyang.

Largest cities, 2022-now

  1. 1 BeijingChina 310 works
  2. 2 ShanghaiChina 275 works
  3. 3 GuangzhouChina 246 works
  4. 4 NanjingChina 146 works
  5. 5 SeoulSouth Korea 144 works
  6. 6 HangzhouChina 140 works
  7. 7 WuhanChina 131 works
  8. 8 ChengduChina 106 works
  9. 9 ChangshaChina 101 works
  10. 10 JinanChina 94 works

Where it is the local speciality

  1. NantongCN · 30.7 works7.3×
  2. HengyangCN · 20.8 works6.6×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Cancer, Lipids, and Metabolism than the world average.

See Cancer, Lipids, and Metabolism on the map

Where is the best place to study Cancer, Lipids, and Metabolism?

Among universities, judged by research, Sun Yat-sen University, Harvard University and Fudan University score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 16.01%fractional works in this field (log) →share of work in the world top 10% →Wuhan UniversitySun Yat-sen UniversityFudan UniversityHarvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Sun Yat-sen UniversityChina 69.917.1%6.7×109 +15.0%
2Harvard UniversityUnited States 69.113.4%3.2×80 +0.3%
3Fudan UniversityChina 64.316.9%5.1×63 +64.5%
4Wuhan UniversityChina 63.622.3%4.1×46 +57.0%
5Central South UniversityChina 62.418.9%3.7×56 +42.5%
6Nanjing Medical UniversityChina 62.312.6%11.1×78 +67.9%
7Zhejiang UniversityChina 61.715.5%3.2×68 +49.6%
8Sichuan UniversityChina 60.416.1%3.5×62 +37.6%
9Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 60.413.8%7.5×62 +26.3%
10Shanghai Jiao Tong UniversityChina 60.113.5%3.2×73 +38.8%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Cancer, Lipids, and Metabolism, country by country

Is Cancer, Lipids, and Metabolism research growing?

Output in 2022-2025 was 18% higher than in 2018-2021, peaking in 2022. The fastest-growing topics are Cancer, Lipids, and Metabolism.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Cancer, Lipids, and Metabolism as a percentage of every work published that year, 0.039% in 2024.

still counting0.020%0.040%0.060%Cancer, Lipids, and Metabolism0.036% in 202519801990200020102020

Fractional works of Cancer, Lipids, and Metabolism over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Cancer, Lipids, and Metabolism10.1% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

Ask a question or share a note about Cancer, Lipids, and Metabolism. Keep it to the research: no personal attacks, advertising or links. Any reader can report a post, which collapses it for everyone until it is opened.