Cancer, Hypoxia, and Metabolism
Cancer, Hypoxia, and Metabolism is a research topic within Cancer Research. Science Explorer counts 79k research works in it since 1950. 17.6% of them reached the world's top 10% most cited for their field and year.
This cluster of papers explores the metabolic reprogramming in cancer cells, focusing on the role of hypoxia-inducible factor 1 (HIF-1), the Warburg effect, tumor hypoxia, glutamine metabolism, and the impact of the tumor microenvironment on cancer cell metabolism. It also delves into oxygen sensing, mitochondrial metabolism, glycolysis inhibition, and the role of hexokinase II in cancer progression.
- HIF-1
- Warburg Effect
- Tumor Hypoxia
- Cancer Cell Metabolism
- Glutamine Metabolism
- Oxygen Sensing
- Mitochondrial Metabolism
- Glycolysis Inhibition
- Tumor Microenvironment
- Hexokinase II
- Research works
- 79k fractional, since 1950
- In the world top 10%
- 14k per year above
- Top-10% rate
- 17.6% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +3% the tick is no change
Which countries lead Cancer, Hypoxia, and Metabolism research?
By volume, China and the United States publish the most (4.6k and 2.8k works in 2022–2025).
By volume, 2022–2025
- 1 China 4.6k works
- 2 United States 2.8k works
- 3 Japan 527 works
- 4 India 492 works
- 5 Germany 365 works
- 6 Italy 338 works
- 7 South Korea 313 works
- 8 United Kingdom 311 works
- 9 France 223 works
- 10 Canada 204 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Cancer, Hypoxia, and Metabolism research?
By volume in 2022–2025, Chinese Academy of Medical Sciences & Peking Union Medical College publishes the most Cancer, Hypoxia, and Metabolism research, followed by Sun Yat-sen University and The University of Texas MD Anderson Cancer Center.
By volume, 2022–2025
- 1 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 75 works
- 2 Sun Yat-sen UniversityChina 73 works
- 3 The University of Texas MD Anderson Cancer CenterUnited States 69 works
- 4 Nanjing Medical UniversityChina 54 works
- 5 Sichuan UniversityChina 54 works
- 6 Shanghai Jiao Tong UniversityChina 51 works
- 7 Huazhong University of Science and TechnologyChina 49 works
- 8 University of MichiganUnited States 45 works
- 9 Fudan UniversityChina 45 works
- 10 Central South UniversityChina 42 works
Who are the leading researchers in Cancer, Hypoxia, and Metabolism?
The most-cited researchers publishing on Cancer, Hypoxia, and Metabolism include Dirk Schadendorf and Guido Kroemer.
- 1 Dirk Schadendorf Germany 4.4k citations
- 2 Guido Kroemer France 4.2k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Cancer, Hypoxia, and Metabolism research done?
The largest centres of Cancer, Hypoxia, and Metabolism research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Luzhou, Zunyi and Shatin.
Largest cities, 2022–2025
Where it is the local speciality
- LuzhouCN · 28.7 works9.8×
- ZunyiCN · 20.0 works8.0×
- ShatinCN · 20.5 works7.1×
Location quotient: how much more of its research is in Cancer, Hypoxia, and Metabolism than the world average.
Where is the best place to study Cancer, Hypoxia, and Metabolism?
Among universities, judged by research, China Pharmaceutical University, Shanghai Medical College of Fudan University and Southern Medical University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | China Pharmaceutical UniversityChina | 67.0 | 35.0% | 11.3× | 29 | +72.1% |
| 2 | Shanghai Medical College of Fudan UniversityChina | 67.0 | 46.1% | 13.6× | 13 | +50.9% |
| 3 | Southern Medical UniversityChina | 62.8 | 30.6% | 9.2× | 40 | +33.6% |
| 4 | China Medical UniversityChina | 62.7 | 34.5% | 10.1× | 39 | -38.0% |
| 5 | Guiyang Medical UniversityChina | 62.0 | 25.5% | 10.2× | 16 | +184.0% |
| 6 | Nanjing Medical UniversityChina | 59.9 | 28.1% | 8.8× | 54 | -12.7% |
| 7 | Zunyi Medical UniversityChina | 59.1 | 27.0% | 8.4× | 16 | +300.6% |
| 8 | Air Force Medical UniversityChina | 57.8 | 37.8% | 9.4× | 19 | -24.8% |
| 9 | Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina | 57.2 | 29.3% | 6.4× | 75 | -17.3% |
| 10 | Harbin Medical UniversityChina | 55.7 | 26.5% | 11.1× | 27 | -8.9% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Cancer, Hypoxia, and Metabolism research growing?
Output in 2018–2022 was 3% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Cancer, Hypoxia, and Metabolism.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.