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Topic · Cancer Research

Beetle Biology and Toxicology Studies

Beetle Biology and Toxicology Studies is a research topic within Cancer Research. Science Explorer counts 4.1k research works in it since 1950. 10.2% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the development and evaluation of protein phosphatase inhibitors, such as Cantharidin and Norcantharidin, as potential anticancer agents. The research involves studying their mechanisms of action, including induction of apoptosis, cell cycle arrest, and inhibition of cancer cell growth. Additionally, the cluster explores the molecular identification of pederin biosynthesis and the pharmacological evaluation of these inhibitors.

  • Protein Phosphatase Inhibitors
  • Cantharidin
  • Norcantharidin
  • Anticancer Activity
  • Apoptosis
  • Cell Cycle Arrest
  • Sponge-Derived Cytotoxin
  • Pederin Biosynthesis
  • Molecular Identification
  • Pharmacological Evaluation
Research works
4.1k
fractional, since 1950
In the world top 10%
423
per year above
Top-10% rate
10.2%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+32%
the tick is no change
Largest producer
China
33% of the 10 largest, 2022-now
Beetle Biology and Toxicology Studies

Which countries lead Beetle Biology and Toxicology Studies research?

By volume, China and the United States publish the most (181 and 96 works in 2022-now).

By volume, 2022-now

  1. 1 China 181 works
  2. 2 United States 96 works
  3. 3 India 83 works
  4. 4 Türkiye 38 works
  5. 5 Italy 32 works
  6. 6 Brazil 28 works
  7. 7 Germany 26 works
  8. 8 Iran 22 works
  9. 9 United Kingdom 21 works
  10. 10 Russia 20 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 33.2%United States: 17.6%India: 15.2%Türkiye: 7.0%6 others listed: 27.1%33%largest
China181 · 33.2%United States96 · 17.6%India83 · 15.2%Türkiye38 · 7.0%6 others listed148 · 27.1%

Shares of the rows listed above, not of the whole node.

Which institutions lead Beetle Biology and Toxicology Studies research?

By volume in 2022-now, Zunyi Medical University publishes the most Beetle Biology and Toxicology Studies research, followed by Russian Academy of Sciences and Chinese Academy of Sciences.

By volume, 2022-now

  1. 1 Zunyi Medical UniversityChina 9 works
  2. 2 Russian Academy of SciencesRussia 9 works
  3. 3 Chinese Academy of SciencesChina 6 works
  4. 4 Centre National de la Recherche ScientifiqueFrance 5 works
  5. 5 Manisa Celal Bayar UniversityTürkiye 5 works
  6. 6 Consejo Nacional de Investigaciones Científicas y TécnicasArgentina 5 works
  7. 7 University of CreteGreece 5 works
  8. 8 Natural History MuseumUnited Kingdom 5 works
  9. 9 Chinese Academy of Agricultural SciencesChina 4 works
  10. 10 University of Tennessee at ChattanoogaUnited States 4 works

Who are the leading researchers in Beetle Biology and Toxicology Studies?

The most-cited researchers publishing on Beetle Biology and Toxicology Studies include Dirk Schadendorf and Kenneth Carl Anderson.

  1. 1 Dirk Schadendorf Germany 222k citations
  2. 2 Kenneth Carl Anderson United States 171k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Beetle Biology and Toxicology Studies?

The most cited paper in Beetle Biology and Toxicology Studies is "Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines." (Dominic A. Scudiero, Robert H. Shoemaker, Kenneth D. Paull et al., 1988), with 2,362 citations. Next come "Hoe 140 a new potent and long acting bradykinin‐antagonist:in vivostudies" (835) and "The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells" (682).

Most cited papers
#PaperReleasedCitations
1 Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Dominic A. Scudiero, Robert H. Shoemaker, Kenneth D. Paull et al. · PubMed Sep 1988 2,362
2 Hoe 140 a new potent and long acting bradykinin‐antagonist:in vivostudies KLAUS J. WIRTH, Franz J. Hock, Udo Albus et al. · British Journal of Pharmacology Open access Mar 1991 835
3 The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells Mónica L. Guzmán, Randall M. Rossi, Lilliana Karnischky et al. · Blood Open access 2 Feb 2005 682
4 Cancer-Associated Mutations in Endometriosis without Cancer Michael S. Anglesio et al. · New England Journal of Medicine Open access 11 May 2017 640
5 A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles Jörn Piel · Proceedings of the National Academy of Sciences Open access 14 Oct 2002 612
All 100 most cited papers, with filters and sorting

Where is Beetle Biology and Toxicology Studies research done?

The largest centres of Beetle Biology and Toxicology Studies research in 2022-now are Beijing (China), Rome (Italy), Guangzhou (China) and Zunyi (China).

Largest cities, 2022-now

  1. 1 BeijingChina 23 works
  2. 2 RomeItaly 14 works
  3. 3 GuangzhouChina 10 works
  4. 4 ZunyiChina 10 works
  5. 5 LondonUnited Kingdom 9 works
  6. 6 São PauloBrazil 9 works
  7. 7 AnkaraTürkiye 8 works
  8. 8 MoscowRussia 8 works
  9. 9 GuiyangChina 8 works
  10. 10 MadridSpain 8 works
See Beetle Biology and Toxicology Studies on the map

Where is the best place to study Beetle Biology and Toxicology Studies?

Among universities, judged by research, Zunyi Medical University score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Zunyi Medical UniversityChina 10.03.8%72.7×9 +43.0%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Beetle Biology and Toxicology Studies, country by country

Is Beetle Biology and Toxicology Studies research growing?

Output in 2022-2025 was 32% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Beetle Biology and Toxicology Studies.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Beetle Biology and Toxicology Studies as a percentage of every work published that year, 0.0025% in 2024.

still counting0.0050%0.010%Beetle Biology and Toxicology Studies0.0045% in 202519801990200020102020

Fractional works of Beetle Biology and Toxicology Studies over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Beetle Biology and Toxicology Studies10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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