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Topic · Beetle Biology and Toxicology Studies

Most cited papers in Beetle Biology and Toxicology Studies

Beetle Biology and Toxicology Studies

What are the most cited papers in Beetle Biology and Toxicology Studies?

The most cited paper in Beetle Biology and Toxicology Studies is "Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines." (Dominic A. Scudiero, Robert H. Shoemaker, Kenneth D. Paull et al., 1988), with 2,362 citations. Next come "Hoe 140 a new potent and long acting bradykinin‐antagonist:in vivostudies" (835) and "The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells" (682).

Showing 50 of 100 papers. Every paper with more than 161 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Dominic A. Scudiero, Robert H. Shoemaker, Kenneth D. Paull et al. · PubMed Sep 1988 2,362
2 Hoe 140 a new potent and long acting bradykinin‐antagonist:in vivostudies KLAUS J. WIRTH, Franz J. Hock, Udo Albus et al. · British Journal of Pharmacology Open access Mar 1991 835
3 The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells Mónica L. Guzmán, Randall M. Rossi, Lilliana Karnischky et al. · Blood Open access 2 Feb 2005 682
4 Cancer-Associated Mutations in Endometriosis without Cancer Michael S. Anglesio et al. · New England Journal of Medicine Open access 11 May 2017 640
5 A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles Jörn Piel · Proceedings of the National Academy of Sciences Open access 14 Oct 2002 612
6 Comparison of 200 mg/m2 melphalan and 8 Gy total body irradiation plus 140 mg/m2 melphalan as conditioning regimens for peripheral blood stem cell transplantation in patients with newly diagnosed multiple myeloma: final analysis of the Intergroupe Francophone du Myelome 9502 randomized trial Philippe Moreau · Blood Open access Feb 2002 570
7 The Pharmacology of mTOR Inhibition David A. Guertin, David M. Sabatini · Science Signaling 21 Apr 2009 569
8 Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei Jörn Piel, Dequan Hui, Gaiping Wen et al. · Proceedings of the National Academy of Sciences Open access Nov 2004 541
9 From traditional Chinese medicine to rational cancer therapy Thomas Efferth, Paul C. H. Li, V. Badireenath Konkimalla et al. · Trends in Molecular Medicine Review 18 Jul 2007 533
10 Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway Pamela Scott, Gregory J. Brunn, Aimee D. Kohn et al. · Proceedings of the National Academy of Sciences Open access 23 Jun 1998 487
11 Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Per Guldberg, Per thor Straten, Anette Birck et al. · PubMed Sep 1997 486
12 Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor J. Fred Hess, Joseph A. Borkowski, Gretchen S. Young et al. · Biochemical and Biophysical Research Communications Apr 1992 475
13 Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells. Enrique Rozengurt, James W. Sinnett‐Smith · Proceedings of the National Academy of Sciences Open access May 1983 467
14 Metastatic melanoma.A clinicopathological study Taposh Das Gupta, Richard D. Brasfield · Cancer Oct 1964 448
15 Medical uses of mylabris in ancient China and recent studies Guang-Sheng Wang · Journal of Ethnopharmacology Sep 1989 424
16 Treatment of Amatoxin Poisoning: 20-Year Retrospective Analysis Françoise Enjalbert, Sylvie Rapior, Janine Nouguier-Soulé et al. · Journal of Toxicology Clinical Toxicology 2002 423
17 An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells Mónica L. Guzmán, Randall M. Rossi, Sundar Neelakantan et al. · Blood Open access 5 Sep 2007 412
18 Multi-targeted therapy of cancer by niclosamide: A new application for an old drug Yonghe Li, Pui‐Kai Li, Michael J. Roberts et al. · Cancer Letters Open access 13 Apr 2014 379
19 Determination of the wound healing effect of Calendula extracts using the scratch assay with 3T3 fibroblasts Márcio Fronza, Berta Maria Heinzmann, Matthias O. Hamburger et al. · Journal of Ethnopharmacology 24 Sep 2009 367
20 Induction of Keratinocyte Migration via Transactivation of the Epidermal Growth Factor Receptor by the Antimicrobial Peptide LL-37 Sho Tokumaru, Koji Sayama, Yuji Shirakata et al. · The Journal of Immunology Oct 2005 361
21 Tumour Production in Glandular Stomach of Rat by N-Methyl-N′-Nitro-N-Nitrosoguanidine Takashi Sügimura, Shinji Fujimura · Nature Dec 1967 357
22 Antifungal activity of plant extracts against dermatophytes Mohammed S. Ali-Shtayeh, Suheil I. Abu Ghdeib · Mycoses Dec 1999 328
23 Effects of Low-Dose Aspirin on Acute Inflammatory Responses in Humans Thea Morris, Melanie J. Stables, Adrian J. Hobbs et al. · The Journal of Immunology Open access 14 Jul 2009 324
24 Mitochondrial and nonmitochondrial reduction of MTT: Interaction of MTT with TMRE, JC‐1, and NAO mitochondrial fluorescent probes Tytus Bernaś, Jurek W. Dobrucki · Cytometry 21 Mar 2002 323
25 Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells. Hajime Hosoi, Michael B. Dilling, Takuma Shikata et al. · PubMed 15 Feb 1999 316
26 Phase I Study of an Immunomodulatory Thalidomide Analog, CC-4047, in Relapsed or Refractory Multiple Myeloma Stephen Schey, Paul A. Fields, J. Blake Bartlett et al. · Journal of Clinical Oncology 13 Jul 2004 315
27 Osteosarcoma treatment: state of the art Hang Thu Ta, Crispin R. Dass, Peter Choong et al. · Cancer and Metastasis Reviews Review 11 Feb 2009 314
28 DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2‐terminal domains stabilizes binding of two dimers to tandem DNA sites. Uwe Vinkemeier, Steven L. Cohen, Ismail Moarefi et al. · The EMBO Journal Open access Oct 1996 307
29 Expression of HER2/erbB-2 Correlates With Survival in Osteosarcoma Richard Greg Gorlick, Andrew G. Huvos, Glenn Heller et al. · Journal of Clinical Oncology Sep 1999 304
30 Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer Stephen Y.T. Chan · British Journal of Cancer Open access 14 Sep 2004 302
31 Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A Richard E. Honkanen · FEBS Letters Open access 20 Sep 1993 291
32 Rapamycins: Mechanisms of Action and Cellular Resistance Shile Huang, Mary‐Ann Bjornsti, Peter John Houghton · Cancer Biology & Therapy Open access 20 May 2003 289
33 Cancer as a channelopathy: ion channels and pumps in tumor development and progression Alisa Litan, Sigrid A. Langhans · Frontiers in Cellular Neuroscience Open access 17 Mar 2015 283
34 Links between apoptosis, proliferation and the cell cycle Faris Q Alenzi · British Journal of Biomedical Science 2004 267
35 Molecular cloning of the cDNA for a growth factor-inducible gene with strong homology to S-100, a calcium-binding protein. Bruno Calabretta, Renata Battini, Leszek Kaczmarek et al. · Journal of Biological Chemistry Open access Sep 1986 265
36 Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines Jamie S. Mader, Jayme Salsman, David Conrad et al. · Molecular Cancer Therapeutics Apr 2005 263
37 Dexamethasone Represses Signaling through the Mammalian Target of Rapamycin in Muscle Cells by Enhancing Expression of REDD1 Hongmei Wang, Neil Kubica, Leif William Ellisen et al. · Journal of Biological Chemistry Open access 31 Oct 2006 262
38 Molecular Pharmacology and Pharmacogenomics of Artemisinin and its Derivatives in Cancer Cells Thomas Efferth · Current Drug Targets 28 Mar 2006 262
39 Regulators of Serine / Threonine Protein Phosphatases at the Dawn of a Clinical Era? Richard E. Honkanen, Teresa A. Golden · Current Medicinal Chemistry Nov 2002 261
40 Loxoscelism Josephine M. Futrell · The American Journal of the Medical Sciences Oct 1992 257
41 Cantharidin-binding protein: identification as protein phosphatase 2A. Y M Li, John E. Casida · Proceedings of the National Academy of Sciences Open access 15 Dec 1992 257
42 Crystal structure of an endotoxin‐neutralizing protein from the horseshoe crab, Limulus anti‐LPS factor, at 1.5 A resolution. Adolf Hoess, Stuart Watson, George R. Siber et al. · The EMBO Journal Open access Sep 1993 256
43 Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris Johanna Rhodes, Alireza Abdolrasouli, Rhys A. Farrer et al. · Emerging Microbes & Infections Open access 3 Apr 2018 250
44 In Vitro and in Vivo Antiplasmodial Activity of Cryptolepine and Related Alkaloids from Cryptolepis sanguinolenta Kanyanga Cimanga, Tess De Bruyne, Luc A. C. Pieters et al. · Journal of Natural Products Jul 1997 250
45 Phase II Study of the Mammalian Target of Rapamycin Inhibitor Ridaforolimus in Patients With Advanced Bone and Soft Tissue Sarcomas Sant P. Chawla, Arthur P. Staddon, Laurence H. Baker et al. · Journal of Clinical Oncology Open access 8 Nov 2011 248
46 Metastatic heterogeneity of cells from an ultraviolet light-induced murine fibrosarcoma of recent origin. Margaret L. Kripke, Eilene Gruys, Isaiah J. Fidler · PubMed Sep 1978 248
47 Activation of Stat3 in Primary Tumors from High-Risk Breast Cancer Patients Is Associated with Elevated Levels of Activated Src and Survivin Expression Nills Diaz, Susan E. Minton, Charles Cox et al. · Clinical Cancer Research 2006 243
48 NTRK Fusions Define a Novel Uterine Sarcoma Subtype With Features of Fibrosarcoma Sarah Chiang, Paolo Cotzia, David Michael Hyman et al. · The American Journal of Surgical Pathology Open access 16 Mar 2018 241
49 Activation of a suicide process of thymocytes through DNA fragmentation by calcium ionophores and phorbol esters. Harutoshi Kizaki, T Tadakuma, C Odaka et al. · The Journal of Immunology Sep 1989 241
50 Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial Ana Oaknin et al. · The Lancet Open access121 authors Dec 2023 239

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.