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Topic · Cancer Research

Carcinogens and Genotoxicity Assessment

Carcinogens and Genotoxicity Assessment is a research topic within Cancer Research. Science Explorer counts 49k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on genotoxicity and carcinogenesis mechanisms, covering topics such as Comet Assay, Micronucleus Assay, DNA damage, environmental monitoring, biomonitoring, mutagenicity, and risk assessment in the context of chemical carcinogens.

  • Comet Assay
  • Genotoxicity Testing
  • Micronucleus Assay
  • DNA Damage
  • Carcinogenesis
  • Environmental Monitoring
  • Biomonitoring
  • Mutagenicity
  • Chemical Carcinogens
  • Risk Assessment
Research works
49k
fractional, since 1950
In the world top 10%
4.9k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-7%
the tick is no change
Largest producer
United States
28% of the 10 largest, 2022-now
Carcinogens and Genotoxicity Assessment

Which countries lead Carcinogens and Genotoxicity Assessment research?

By volume, the United States and China publish the most (748 and 661 works in 2022-now).

By volume, 2022-now

  1. 1 United States 748 works
  2. 2 China 661 works
  3. 3 India 243 works
  4. 4 Germany 188 works
  5. 5 Brazil 187 works
  6. 6 Japan 173 works
  7. 7 France 121 works
  8. 8 South Korea 117 works
  9. 9 Türkiye 113 works
  10. 10 Italy 112 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 28.1%China: 24.8%India: 9.1%Germany: 7.1%6 others listed: 30.9%28%largest
United States748 · 28.1%China661 · 24.8%India243 · 9.1%Germany188 · 7.1%6 others listed823 · 30.9%

Shares of the rows listed above, not of the whole node.

Which institutions lead Carcinogens and Genotoxicity Assessment research?

By volume in 2022-now, National Institutes of Health publishes the most Carcinogens and Genotoxicity Assessment research, followed by Russian Academy of Sciences and Helmholtz Association of German Research Centres.

By volume, 2022-now

  1. 1 National Institutes of HealthUnited States 30 works
  2. 2 Russian Academy of SciencesRussia 30 works
  3. 3 Helmholtz Association of German Research CentresGermany 28 works
  4. 4 Chinese Academy of SciencesChina 23 works
  5. 5 InsermFrance 16 works
  6. 6 United States Food and Drug AdministrationUnited States 15 works
  7. 7 Centre National de la Recherche ScientifiqueFrance 14 works
  8. 8 Universidade de São PauloBrazil 13 works
  9. 9 University of LouisvilleUnited States 13 works
  10. 10 Huazhong University of Science and TechnologyChina 13 works

Who are the leading researchers in Carcinogens and Genotoxicity Assessment?

The most-cited researchers publishing on Carcinogens and Genotoxicity Assessment include Ahmedin Jemal, Freddie Bray and George Davey Smith.

  1. 1 Ahmedin Jemal United States 761k citations
  2. 2 Freddie Bray France 550k citations
  3. 3 George Davey Smith United Kingdom 435k citations
  4. 4 Walter Churchill Willett United States 411k citations
  5. 5 Guido Kroemer France 386k citations
  6. 6 Elaine R. Mardis United States 346k citations
  7. 7 Hermann Brenner Germany 343k citations
  8. 8 Jun Wang China 340k citations
  9. 9 Isabelle Soerjomataram France 327k citations
  10. 10 Robert A. Weinberg United States 301k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Carcinogens and Genotoxicity Assessment?

The most cited paper in Carcinogens and Genotoxicity Assessment is "Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues" (Haider Raza, Annie John, Abderrahim Nemmar, 2013), with 47,289 citations. Next come "A simple salting out procedure for extracting DNA from human nucleated cells" (20,633) and "A simple technique for quantitation of low levels of DNA damage in individual cells" (10,851).

Most cited papers
#PaperReleasedCitations
1 Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues Haider Raza, Annie John, Abderrahim Nemmar · Cellular Physiology and Biochemistry Open access 2013 47,289
2 A simple salting out procedure for extracting DNA from human nucleated cells S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research Open access 1988 20,633
3 A simple technique for quantitation of low levels of DNA damage in individual cells Narendra Prasad Singh, Michael T. McCoy, Raymond R. Tice et al. · Experimental Cell Research Mar 1988 10,851
4 Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. Yael Gavrieli, Yoav Sherman, Shmuel A. Ben‐Sasson · The Journal of Cell Biology Open access Nov 1992 9,552
5 Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test Bruce N. Ames, Joyce McCann, Edith F. Yamasaki · Mutation Research/Environmental Mutagenesis and Related Subjects Dec 1975 7,423
All 100 most cited papers, with filters and sorting

Where is Carcinogens and Genotoxicity Assessment research done?

The largest centres of Carcinogens and Genotoxicity Assessment research in 2022-now are Beijing (China), Tokyo (Japan), Guangzhou (China) and Seoul (South Korea). Among places with at least 20 works in it, it is an unusually large share of all research in Karlsruhe and Durham.

Largest cities, 2022-now

  1. 1 BeijingChina 111 works
  2. 2 TokyoJapan 58 works
  3. 3 GuangzhouChina 58 works
  4. 4 SeoulSouth Korea 49 works
  5. 5 MoscowRussia 43 works
  6. 6 ShanghaiChina 40 works
  7. 7 São PauloBrazil 37 works
  8. 8 New YorkUnited States 37 works
  9. 9 ParisFrance 35 works
  10. 10 LondonUnited Kingdom 34 works

Where it is the local speciality

  1. KarlsruheDE · 24.8 works8.3×
  2. DurhamUS · 24.0 works5.0×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Carcinogens and Genotoxicity Assessment than the world average.

See Carcinogens and Genotoxicity Assessment on the map

Where is the best place to study Carcinogens and Genotoxicity Assessment?

Among universities, judged by research, Huazhong University of Science and Technology, Harvard University and Shanghai Jiao Tong University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 17.16%fractional works in this field (log) →share of work in the world top 10% →Huazhong University …Sun Yat-sen UniversityShanghai Jiao Tong U…Harvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Huazhong University of Science and TechnologyChina 77.320.8%2.1×13 +39.0%
2Harvard UniversityUnited States 70.313.2%1.1×12 -11.6%
3Shanghai Jiao Tong UniversityChina 67.816.2%1.2×12 +51.4%
4Sun Yat-sen UniversityChina 66.516.6%1.7×12 +78.6%
5Nanjing Medical UniversityChina 65.722.9%3.3×10 +47.2%
6Wageningen University & ResearchNetherlands 64.711.9%7.6×10 +58.2%
7University of LouisvilleUnited States 64.28.6%13.7×13 +91.4%
8Anhui Medical UniversityChina 64.122.8%6.0×10 +102.8%
9Sichuan UniversityChina 60.021.3%1.4×11 +75.1%
10University of CopenhagenDenmark 58.917.3%2.5×8 +1.9%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Carcinogens and Genotoxicity Assessment, country by country

Is Carcinogens and Genotoxicity Assessment research growing?

Output in 2022-2025 was 7% lower than in 2018-2021, peaking in 2014.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Carcinogens and Genotoxicity Assessment as a percentage of every work published that year, 0.015% in 2024.

still counting0.10%0.20%Carcinogens and Genotoxicity Assessment0.017% in 202519801990200020102020

Fractional works of Carcinogens and Genotoxicity Assessment over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Carcinogens and Genotoxicity Assessment10.2% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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