Most cited papers in Carcinogens and Genotoxicity Assessment
What are the most cited papers in Carcinogens and Genotoxicity Assessment?
The most cited paper in Carcinogens and Genotoxicity Assessment is "Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues" (Haider Raza, Annie John, Abderrahim Nemmar, 2013), with 47,289 citations. Next come "A simple salting out procedure for extracting DNA from human nucleated cells" (20,633) and "A simple technique for quantitation of low levels of DNA damage in individual cells" (10,851).
Showing 50 of 100 papers. Every paper with more than 1,224 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues Haider Raza, Annie John, Abderrahim Nemmar · Cellular Physiology and Biochemistry | 2013 | 47,289 |
| 2 | A simple salting out procedure for extracting DNA from human nucleated cells S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research | 1988 | 20,633 |
| 3 | A simple technique for quantitation of low levels of DNA damage in individual cells Narendra Prasad Singh, Michael T. McCoy, Raymond R. Tice et al. · Experimental Cell Research | Mar 1988 | 10,851 |
| 4 | Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. Yael Gavrieli, Yoav Sherman, Shmuel A. Ben‐Sasson · The Journal of Cell Biology | Nov 1992 | 9,552 |
| 5 | Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test Bruce N. Ames, Joyce McCann, Edith F. Yamasaki · Mutation Research/Environmental Mutagenesis and Related Subjects | Dec 1975 | 7,423 |
| 6 | Revised methods for the Salmonella mutagenicity test Dorothy M. Maron, Bruce N. Ames · Mutation Research/Environmental Mutagenesis and Related Subjects | Mar 1983 | 7,400 |
| 7 | The DNA-damage response in human biology and disease Stephen P. Jackson, Jiří Bártek · Nature | 20 Oct 2009 | 6,194 |
| 8 | Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing Raymond R. Tice, Eva Agurell, Diana Anderson et al. · Environmental and Molecular Mutagenesis | 6 Jun 2000 | 4,883 |
| 9 | Clonogenic assay of cells in vitro Nicolaas A.P. Franken, Hans M. Rodermond, Jan Stap et al. · Nature Protocols | Dec 2006 | 4,254 |
| 10 | Dose-Response Analysis Using R Christian Ritz, Florent Baty, Jens Carl Streibig et al. · PLoS ONE | 30 Dec 2015 | 3,885 |
| 11 | The 2005 World Health Organization Reevaluation of Human and Mammalian Toxic Equivalency Factors for Dioxins and Dioxin-Like Compounds Martin van den Berg, Linda S. Birnbaum, Michael S. Denison et al. · Toxicological Sciences | 7 Jul 2006 | 3,805 |
| 12 | A review on polycyclic aromatic hydrocarbons: Source, environmental impact, effect on human health and remediation Hussein I. Abdel‐Shafy, Mona S. M. Mansour · Egyptian Journal of Petroleum | 19 Dec 2015 | 3,592 |
| 13 | DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation Christopher J. Bakkenist, Michael B. Kastan · Nature | 2003 | 3,474 |
| 14 | Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity John O’Brien, Ian D. Wilson, Terry C. Orton et al. · European Journal of Biochemistry | Sep 2000 | 3,452 |
| 15 | Bromobenzene-Induced Liver Necrosis. Protective Role of Glutathione and Evidence for 3,4-Bromobenzene Oxide as the Hepatotoxic Metabolite David J. Jollow, John R.D. Mitchell, NICOLA G. ZAMPAGLIONE et al. · Pharmacology | 28 May 2008 | 3,308 |
| 16 | Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Martin van den Berg et al. · Environmental Health Perspectives | Dec 1998 | 3,266 |
| 17 | Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses Laura N. Vandenberg, Theo L. Colborn, Tyrone B. Hayes et al. · Endocrine Reviews | 14 Mar 2012 | 3,182 |
| 18 | IARC monographs on the evaluation of carcinogenic risks to humans James C. A. Hopkins · Food and Chemical Toxicology | 1989 | 2,898 |
| 19 | Human exposure to bisphenol A (BPA) Laura N. Vandenberg, Russ B. Hauser, Michele Marcus et al. · Reproductive Toxicology | Aug 2007 | 2,890 |
| 20 | The Comet Assay for DNA Damage and Repair: Principles, Applications, and Limitations Andrew Richard Collins · Molecular Biotechnology | 2004 | 2,887 |
| 21 | Cell-cycle checkpoints and cancer Michael B. Kastan, Jiří Bártek · Nature | Nov 2004 | 2,852 |
| 22 | Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics | Jul 1994 | 2,793 |
| 23 | DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis Jiřina Bártková, Zuzana Hořejšı́, Karen Koed et al. · Nature | Apr 2005 | 2,714 |
| 24 | ATM and related protein kinases: safeguarding genome integrity Yosef Shiloh · Nature reviews. Cancer | 28 Feb 2003 | 2,584 |
| 25 | Prooxidant States and Tumor Promotion P Cerutti · Science | 25 Jan 1985 | 2,515 |
| 26 | The in vitro micronucleus technique Michael Felix Fenech · Mutation research. Fundamental and molecular mechanisms of mutagenesis | Nov 2000 | 2,512 |
| 27 | DNA double-strand breaks: signaling, repair and the cancer connection Kum Kum Khanna, Stephen P. Jackson · Nature Genetics | Mar 2001 | 2,484 |
| 28 | Men at risk: occupation and male infertility Paul Claman · Fertility and Sterility | Mar 2004 | 2,392 |
| 29 | Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection Bruce N. Ames, William E. Durston, Edith F. Yamasaki et al. · Proceedings of the National Academy of Sciences | Aug 1973 | 2,296 |
| 30 | DNA Damage, Aging, and Cancer Jan H.J. Hoeijmakers · New England Journal of Medicine | 7 Oct 2009 | 2,241 |
| 31 | Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG Shinya Shibutani, Masaru Takeshita, Arthur P. Grollman · Nature | 1991 | 2,234 |
| 32 | ROS and the DNA damage response in cancer Upadhyayula Sai Srinivas, Bryce Wei Quan Tan, Balamurugan A. Vellayappan et al. · Redox Biology | 20 Dec 2018 | 2,163 |
| 33 | The Ames Salmonella/microsome mutagenicity assay Kristien E. Mortelmans, Errol Zeiger · Mutation research. Fundamental and molecular mechanisms of mutagenesis | Nov 2000 | 2,113 |
| 34 | Mechanisms of DNA damage, repair, and mutagenesis Nimrat Chatterjee, Graham Charles Walker · Environmental and Molecular Mutagenesis | 9 May 2017 | 2,101 |
| 35 | Measurement of the incorporation of radioactive amino acids into protein by a filter-paper disk method Rusty J. Mans, G. David Novelli · Archives of Biochemistry and Biophysics | Jul 1961 | 2,052 |
| 36 | ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response Andrew N. Blackford, Stephen P. Jackson · Molecular Cell | Jun 2017 | 2,043 |
| 37 | Cytokinesis-block micronucleus cytome assay Michael Felix Fenech · Nature Protocols | May 2007 | 2,024 |
| 38 | Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions Vassilis G. Gorgoulis, Leandros-Vassilios F. Vassiliou, Panagiotis Karakaidos et al. · Nature | Apr 2005 | 2,018 |
| 39 | 8-hydroxy-2′ -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis Athanasios Valavanidis, Thomais Vlachogianni, CONSTANTINOS FIOTAKIS · Journal of Environmental Science and Health Part C | 2 May 2009 | 2,003 |
| 40 | Tobacco Smoke Carcinogens and Lung Cancer Stephen S. Hecht · JNCI Journal of the National Cancer Institute | 21 Jul 1999 | 1,990 |
| 41 | ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks Sandeep Burma, Benjamin P. Chen, Michael B. Murphy et al. · Journal of Biological Chemistry | Nov 2001 | 1,985 |
| 42 | Urinary Creatinine Concentrations in the U.S. Population: Implications for Urinary Biologic Monitoring Measurements Dana Boyd Barr, Lynn C. Wilder, Samuel P. Caudill et al. · Environmental Health Perspectives | 23 Sep 2004 | 1,960 |
| 43 | Toxicity determined in vitro by morphological alterations and neutral red absorption Ellen Borenfreund, James A. Puerner · Toxicology Letters | Feb 1985 | 1,902 |
| 44 | Oxyradicals and DNA damage Lawrence J. Marnett · Carcinogenesis | Mar 2000 | 1,895 |
| 45 | Polychlorinated Biphenyls (PCBs), Dibenzo-p-Dioxins (PCDDs), Dibenzofurans (PCDFs), and Related Compounds: Environmental and Mechanistic Considerations Which Support the Development of Toxic Equivalency Factors (TEFs) Stephen H Safe · Critical Reviews in Toxicology | 1990 | 1,876 |
| 46 | 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions. Keith C. Cheng, D S Cahill, Hiroshi Kasai et al. · Journal of Biological Chemistry | 1992 | 1,863 |
| 47 | The comet assay: a method to measure DNA damage in individual cells Peggy L. Olive, Judit Püspöky Banáth · Nature Protocols | Jun 2006 | 1,858 |
| 48 | Measurement of micronuclei in lymphocytes Michael Felix Fenech, Alexander A. Morley · Mutation Research/Environmental Mutagenesis and Related Subjects | Feb 1985 | 1,819 |
| 49 | Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage Sharon Banin, Lilach Moyal, Sheau-Yann Shieh et al. · Science | 11 Sep 1998 | 1,806 |
| 50 | Defective Repair Replication of DNA in Xeroderma Pigmentosum James E. Cleaver · Nature | May 1968 | 1,744 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.