Topic · Cancer, Lipids, and Metabolism
Most cited papers in Cancer, Lipids, and Metabolism
What are the most cited papers in Cancer, Lipids, and Metabolism?
The most cited paper in Cancer, Lipids, and Metabolism is "Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge" (William T. Friedewald, Robert I. Levy, Donald S. Fredrickson, 1972), with 32,670 citations. Next come "Angiogenesis in cancer and other diseases" (9,128) and "THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM" (8,822).
Showing 50 of 100 papers. Every paper with more than 1,421 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge William T. Friedewald, Robert I. Levy, Donald S. Fredrickson · Clinical Chemistry | Jun 1972 | 32,670 |
| 2 | Angiogenesis in cancer and other diseases Peter Carmeliet, Rakesh K. Jain · Nature | Sep 2000 | 9,128 |
| 3 | THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM Richard J. Havel, Howard A. Eder, Joseph H. Bragdon · Journal of Clinical Investigation | Sep 1955 | 8,822 |
| 4 | Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease Brent R. Stockwell et al. · Cell | Oct 2017 | 7,867 |
| 5 | Regulation of Ferroptotic Cancer Cell Death by GPX4 Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell | 2014 | 7,814 |
| 6 | Ferroptosis: mechanisms, biology and role in disease Xuejun Jiang, Brent R. Stockwell, Marcus Conrad · Nature Reviews Molecular Cell Biology | 25 Jan 2021 | 7,650 |
| 7 | Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia James Banks Shepherd, Stuart M. Cobbe, Ian Ford et al. · New England Journal of Medicine | 16 Nov 1995 | 7,501 |
| 8 | Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review Hiroshi Maeda, Jun Wu, Tomohiro Sawa et al. · Journal of Controlled Release | Mar 2000 | 6,577 |
| 9 | Mechanisms of angiogenesis Werner Risau · Nature | Apr 1997 | 5,752 |
| 10 | Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study G · New England Journal of Medicine | 5 Nov 1998 | 5,307 |
| 11 | Intensive versus Moderate Lipid Lowering with Statins after Acute Coronary Syndromes Christopher Paul Cannon, Eugene Braunwald, Carolyn H. McCabe et al. · New England Journal of Medicine | 7 Apr 2004 | 4,973 |
| 12 | Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes Christopher P. Cannon et al. · New England Journal of Medicine | 4 Jun 2015 | 4,523 |
| 13 | Abiraterone and Increased Survival in Metastatic Prostate Cancer Johann Sebastian De Bono et al. · New England Journal of Medicine | 25 May 2011 | 4,448 |
| 14 | Ferroptosis: molecular mechanisms and health implications Daolin Tang, Xin Chen, Rui Kang et al. · Cell Research | 2 Dec 2020 | 4,365 |
| 15 | ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition Sebastian G. Doll et al. · Nature Chemical Biology | 14 Nov 2016 | 4,302 |
| 16 | Ferroptosis: past, present and future Jie Li, Feng Cao, He-liang Yin et al. · Cell Death and Disease | 3 Feb 2020 | 4,259 |
| 17 | Tamoxifen for early breast cancer: an overview of the randomised trials Abe, Osahiko, Bartholomeus, Sylvie, Piccart-Gebhart, Martine · The Lancet | May 1998 | 4,118 |
| 18 | Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology Robert W. Mahley · Science | 29 Apr 1988 | 4,054 |
| 19 | Helsinki Heart Study: Primary-Prevention Trial with Gemfibrozil in Middle-Aged Men with Dyslipidemia M. H. Frick, Olli Elo, Kauko Haapa et al. · New England Journal of Medicine | 12 Nov 1987 | 3,901 |
| 20 | The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor Michael S. Brown, Joseph L. Goldstein · Cell | May 1997 | 3,866 |
| 21 | Ferroptosis: process and function Yang Xie, Wen‐Chi Hou, Xinxin Song et al. · Cell Death and Differentiation | 22 Jan 2016 | 3,847 |
| 22 | Prognosis of Hepatocellular Carcinoma: The BCLC Staging Classification Josep Maria Llovet, Concepció Brú, Jordi Bruix · Seminars in Liver Disease | 1999 | 3,836 |
| 23 | Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice José Pedro Friedmann Angeli et al. · Nature Cell Biology | 17 Nov 2014 | 3,780 |
| 24 | Integrative Clinical Genomics of Advanced Prostate Cancer Dan R. Robinson et al. · Cell | May 2015 | 3,727 |
| 25 | Effects of a Combination of Beta Carotene and Vitamin A on Lung Cancer and Cardiovascular Disease Gilbert S. Omenn, Gary E. Goodman, Mark D. Thornquist et al. · New England Journal of Medicine | 2 May 1996 | 3,667 |
| 26 | Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms Eugenia E. Calle, Rudolf Kaaks · Nature reviews. Cancer | 30 Jul 2004 | 3,628 |
| 27 | Intensive Lipid Lowering with Atorvastatin in Patients with Stable Coronary Disease John C. LaRosa, Scott M. Grundy, David D. Waters et al. · New England Journal of Medicine | 9 Mar 2005 | 3,517 |
| 28 | Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial James Banks Shepherd, Gerard J. Blauw, Michael B. Murphy et al. · The Lancet | Nov 2002 | 3,409 |
| 29 | FSP1 is a glutathione-independent ferroptosis suppressor Sebastian G. Doll et al. · Nature | 21 Oct 2019 | 3,394 |
| 30 | The Molecular Taxonomy of Primary Prostate Cancer Adam A. Abeshouse et al. · Cell | Nov 2015 | 3,300 |
| 31 | Ferroptosis: Death by Lipid Peroxidation Wan Seok Yang, Brent R. Stockwell · Trends in Cell Biology | 2 Dec 2015 | 3,183 |
| 32 | Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications Brent R. Stockwell · Cell | Jul 2022 | 3,121 |
| 33 | Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis Javier A. Menéndez, Ruth Lupu · Nature reviews. Cancer | 20 Sep 2007 | 3,020 |
| 34 | Broadening horizons: the role of ferroptosis in cancer Xin Chen, Rui Kang, Guido Kroemer et al. · Nature Reviews Clinical Oncology | 29 Jan 2021 | 3,006 |
| 35 | High-Dose Atorvastatin after Stroke or Transient Ischemic Attack The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Inv · New England Journal of Medicine | 9 Aug 2006 | 2,914 |
| 36 | Epidemiology of Prostate Cancer Prashanth Rawla · World Journal of Oncology | 2019 | 2,838 |
| 37 | Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies NaNa Keum, Edward L. Giovannucci · Nature Reviews Gastroenterology & Hepatology | 27 Aug 2019 | 2,814 |
| 38 | The Mechanisms of Action of PPARs Joel P. Berger, David E. Moller · Annual Review of Medicine | Feb 2002 | 2,684 |
| 39 | Targeting Ferroptosis to Iron Out Cancer Behrouz Hassannia, Peter Vandenabeele, Tom Vanden Berghe · Cancer Cell | 16 May 2019 | 2,629 |
| 40 | Regulation of angiogenesis by hypoxia: role of the HIF system Christopher William Pugh, Peter John Ratcliffe · Nature Medicine | 30 May 2003 | 2,540 |
| 41 | The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial Colin Baigent et al. · The Lancet | Jun 2011 | 2,492 |
| 42 | Hepatocellular carcinoma Arndt Vogel, Tim Meyer, Gonzalo Sapisochín et al. · The Lancet | 6 Sep 2022 | 2,424 |
| 43 | The plasma lecithin:cholesterol acyltransferase reaction John A. Glomset · Journal of Lipid Research | Mar 1968 | 2,420 |
| 44 | Lack of Effect of Long-Term Supplementation with Beta Carotene on the Incidence of Malignant Neoplasms and Cardiovascular Disease Charles H. Hennekens, Julie E. Buring, JoAnn E. Manson et al. · New England Journal of Medicine | 2 May 1996 | 2,416 |
| 45 | Effect of Intensive Compared With Moderate Lipid-Lowering Therapy on Progression of Coronary Atherosclerosis Steven E. Nissen, Emin Murat Tuzcu, Paul Schoenhagen et al. · JAMA | 2 Mar 2004 | 2,366 |
| 46 | Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor Susan L. Acton, Attilio Rigotti, Katherine T. Landschulz et al. · Science | 26 Jan 1996 | 2,354 |
| 47 | Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth Kristin M. Nieman, Hilary A. Kenny, Carla V. Penicka et al. · Nature Medicine | 30 Oct 2011 | 2,326 |
| 48 | C-Reactive Protein Levels and Outcomes after Statin Therapy Paul M. Ridker, Christopher Paul Cannon, David A. Morrow et al. · New England Journal of Medicine | 5 Jan 2005 | 2,308 |
| 49 | Targeting ferroptosis as a vulnerability in cancer Guang Lei, Li Zhuang, Boyi Gan · Nature reviews. Cancer | 25 Mar 2022 | 2,268 |
| 50 | Angiogenesis: an organizing principle for drug discovery? Judah Folkman · Nature Reviews Drug Discovery | 30 Mar 2007 | 2,257 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.