Topic · Cancer Genomics and Diagnostics
Most cited papers in Cancer Genomics and Diagnostics
What are the most cited papers in Cancer Genomics and Diagnostics?
The most cited paper in Cancer Genomics and Diagnostics is "Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology" (Sue M. Richards, Nazneen Aziz, Sherri J. Bale et al., 2015), with 33,443 citations. Next come "Cancer statistics, 2020" (21,499) and "The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data" (18,789).
Showing 50 of 100 papers. Every paper with more than 3,278 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology Sue M. Richards, Nazneen Aziz, Sherri J. Bale et al. · Genetics in Medicine | 5 Mar 2015 | 33,443 |
| 2 | Cancer statistics, 2020 Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians | 2020 | 21,499 |
| 3 | The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data Ethan G Cerami, Jianjiong Gao, Uğur Doğrusöz et al. · Cancer Discovery | May 2012 | 18,789 |
| 4 | Cancer Statistics, 2021 Rebecca L. Siegel, Kimberly D. Miller, Hannah E. Fuchs et al. · CA A Cancer Journal for Clinicians | 2021 | 17,460 |
| 5 | Integrative genomics viewer James Theodore Robinson, Helga Thorvaldsdóttir, Wendy Winckler et al. · Nature Biotechnology | 2011 | 16,977 |
| 6 | Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal Jianjiong Gao, Bülent Arman Aksoy, Uğur Doğrusöz et al. · Science Signaling | 2 Apr 2013 | 16,184 |
| 7 | Integrating single-cell transcriptomic data across different conditions, technologies, and species Andrew W. Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology | 2 Apr 2018 | 15,109 |
| 8 | Comprehensive molecular portraits of human breast tumours The Cancer Genome Atlas Network · Nature | 21 Sep 2012 | 12,624 |
| 9 | A genetic model for colorectal tumorigenesis Eric R. Fearon, Bert Vogelstein · Cell | Jun 1990 | 12,218 |
| 10 | Toxicity and response criteria of the Eastern Cooperative Oncology Group Martin M. Oken, Richard H. Creech, Douglass C. Tormey et al. · American Journal of Clinical Oncology | Dec 1982 | 11,816 |
| 11 | Inferring tumour purity and stromal and immune cell admixture from expression data Kosuke Yoshihara, Maria Shahmoradgoli, Emmanuel Martínez et al. · Nature Communications | 11 Oct 2013 | 10,966 |
| 12 | Prospective identification of tumorigenic breast cancer cells Muhammad Al‐Hajj, Max S. Wicha, Adalberto Benito‐Hernández et al. · Proceedings of the National Academy of Sciences | 10 Mar 2003 | 10,455 |
| 13 | Signatures of mutational processes in human cancer Australian Pancreatic Cancer Genome Initiative et al. · Nature | 14 Aug 2013 | 10,284 |
| 14 | The UK Biobank resource with deep phenotyping and genomic data Clare Bycroft, Colin Freeman, Desislava Petkova et al. · Nature | 2 Oct 2018 | 10,121 |
| 15 | Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration Helga Thorvaldsdóttir, James Theodore Robinson, Jill P. Mesirov · Briefings in Bioinformatics | 19 Apr 2012 | 10,012 |
| 16 | The Cancer Genome Atlas Pan-Cancer analysis project John N. Weinstein, Eric A Collisson, Gordon Brent Mills et al. · Nature Genetics | 26 Sep 2013 | 9,847 |
| 17 | The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity Jordi Barretina et al. · Nature | 27 Mar 2012 | 8,623 |
| 18 | Cancer Genome Landscapes Bert Vogelstein, Nickolas Papadopoulos, Victor E. Velculescu et al. · Science | 28 Mar 2013 | 8,204 |
| 19 | Massively parallel digital transcriptional profiling of single cells Grace X. Y. Zheng et al. · Nature Communications | 16 Jan 2017 | 8,144 |
| 20 | p53 Mutations in Human Cancers Monica C. Hollstein, David Sidransky, Bert Vogelstein et al. · Science | 5 Jul 1991 | 8,130 |
| 21 | Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer Naiyer A. Rizvi et al. · Science | 12 Mar 2015 | 8,049 |
| 22 | Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing Marco Gerlinger et al. · New England Journal of Medicine | 7 Mar 2012 | 7,931 |
| 23 | FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer Thierry Conroy, Françoise Desseigne, Marc Ychou et al. · New England Journal of Medicine | 11 May 2011 | 7,927 |
| 24 | Comprehensive genomic characterization defines human glioblastoma genes and core pathways Roger E. McLendon et al. · Nature | 4 Sep 2008 | 7,893 |
| 25 | Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1 Roel G.W. Verhaak et al. · Cancer Cell | 2010 | 7,880 |
| 26 | Mutation and Cancer: Statistical Study of Retinoblastoma Alfred G. Knudson · Proceedings of the National Academy of Sciences | Apr 1971 | 7,700 |
| 27 | Genetic Alterations during Colorectal-Tumor Development Bert Vogelstein, Eric R. Fearon, Stanley R. Hamilton et al. · New England Journal of Medicine | Sep 1988 | 6,787 |
| 28 | The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population‐based to a more “personalized” approach to cancer staging Mahul B. Amin, Frederick L. Greene, Stephen B. Edge et al. · CA A Cancer Journal for Clinicians | 17 Jan 2017 | 6,689 |
| 29 | The Clonal Evolution of Tumor Cell Populations Peter C. Nowell̀ · Science | Oct 1976 | 6,631 |
| 30 | UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses Darshan Shimoga Chandrashekar, Bhuwan Bashel, Sai Akshaya Hodigere Balasubramanya et al. · Neoplasia | 18 Jul 2017 | 6,610 |
| 31 | The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups METABRIC Group et al. · Nature | 17 Apr 2012 | 6,505 |
| 32 | The Immune Landscape of Cancer Vésteinn Thórsson et al. · Immunity | Apr 2018 | 6,328 |
| 33 | Comprehensive molecular profiling of lung adenocarcinoma Eric A. Collisson et al. · Nature | 8 Jul 2014 | 5,968 |
| 34 | Integrated genomic characterization of endometrial carcinoma Douglas A. Levine · Nature | 30 Apr 2013 | 5,963 |
| 35 | An Integrated Genomic Analysis of Human Glioblastoma Multiforme Donald Williams Parsons et al. · Science | 4 Sep 2008 | 5,914 |
| 36 | Mutational heterogeneity in cancer and the search for new cancer-associated genes Michael S. Lawrence et al. · Nature | 16 Jun 2013 | 5,797 |
| 37 | Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response Peng Jiang, Shengqing Stan Gu, Deng Pan et al. · Nature Medicine | 13 Aug 2018 | 5,708 |
| 38 | Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies Brian David Lehmann, Joshua A. Bauer, Xi Chen et al. · Journal of Clinical Investigation | 10 Jun 2011 | 5,662 |
| 39 | Reversed graph embedding resolves complex single-cell trajectories Xiaojie Qiu, Qi Rong Mao, Ying Tang et al. · Nature Methods | 21 Aug 2017 | 5,638 |
| 40 | Maftools: efficient and comprehensive analysis of somatic variants in cancer Anand Mayakonda, De‐Chen Lin, Yassen Assenov et al. · Genome Research | 19 Oct 2018 | 5,587 |
| 41 | Dictionary learning for integrative, multimodal and scalable single-cell analysis Yuhan Hao, Tim Stuart, Madeline H. Kowalski et al. · Nature Biotechnology | 25 May 2023 | 5,523 |
| 42 | Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade Pornpimol Charoentong, Francesca Finotello, Mihaela Angelova et al. · Cell Reports | 2017 | 5,483 |
| 43 | VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing Daniel C. Koboldt, Qunyuan Zhang, David E. Larson et al. · Genome Research | 2 Feb 2012 | 5,412 |
| 44 | COSMIC: the Catalogue Of Somatic Mutations In Cancer John G. Tate et al. · Nucleic Acids Research | 11 Oct 2018 | 5,379 |
| 45 | A New Initiative on Precision Medicine Francis S. Collins, HAROLD E. VARMUS · New England Journal of Medicine | 30 Jan 2015 | 5,301 |
| 46 | The Somatic Genomic Landscape of Glioblastoma Cameron Brennan et al. · Cell | Oct 2013 | 5,261 |
| 47 | Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies Chetan Bettegowda et al. · Science Translational Medicine | 19 Feb 2014 | 5,211 |
| 48 | The biology and management of non-small cell lung cancer Roy S. Herbst, Daniel Morgensztern, CHRIS H. BOSHOFF · Nature | 2018 | 5,116 |
| 49 | ras oncogenes in human cancer: a review. Joyce Bos · PubMed | Sep 1989 | 5,101 |
| 50 | Determining cell type abundance and expression from bulk tissues with digital cytometry Aaron M. Newman, Chloé Beate Steen, Chih Long Liu et al. · Nature Biotechnology | 6 May 2019 | 5,050 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.