Most cited papers from Duke Medical Center
What are the most cited papers from Duke Medical Center?
The most cited paper from Duke Medical Center is "PHENIX : a comprehensive Python-based system for macromolecular structure solution" (Paul D. Adams, Pavel V. Afonine, G. Bunkóczi et al., 2010), with 24,924 citations. Next come "An integrated encyclopedia of DNA elements in the human genome" (19,751) and "Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels" (12,959).
Showing 50 of 59 papers. Every paper with more than 3,069 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | PHENIX : a comprehensive Python-based system for macromolecular structure solution Paul D. Adams, Pavel V. Afonine, G. Bunkóczi et al. · Acta Crystallographica Section D Biological Crystallography | 21 Jan 2010 | 24,924 |
| 2 | An integrated encyclopedia of DNA elements in the human genome Ian Dunham et al. · Nature | Sep 2012 | 19,751 |
| 3 | Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels Charles Beauchamp, Irwin Fridovich · Analytical Biochemistry | Nov 1971 | 12,959 |
| 4 | Superoxide Dismutase Joe M. McCord, Irwin Fridovich · Journal of Biological Chemistry | Nov 1969 | 12,906 |
| 5 | Development of a new resilience scale: The Connor-Davidson Resilience Scale (CD-RISC) Kathryn M. Connor, Jonathan R. T. Davidson · Depression and Anxiety | Sep 2003 | 11,835 |
| 6 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Clotilde Théry et al. · Journal of Extracellular Vesicles | 23 Nov 2018 | 11,535 |
| 7 | MULTIVARIABLE PROGNOSTIC MODELS: ISSUES IN DEVELOPING MODELS, EVALUATING ASSUMPTIONS AND ADEQUACY, AND MEASURING AND REDUCING ERRORS Frank E. Harrell, Kerry L. Lee, Daniel B. Mark · Statistics in Medicine | 29 Feb 1996 | 10,006 |
| 8 | Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter et al. · Science | 13 Aug 1993 | 9,582 |
| 9 | Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer H. Borghaei et al. · New England Journal of Medicine | 27 Sep 2015 | 9,557 |
| 10 | Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation Manesh R. Patel, Kenneth W. Mahaffey, Jyotsna Garg et al. · New England Journal of Medicine | 10 Aug 2011 | 9,484 |
| 11 | Apixaban versus Warfarin in Patients with Atrial Fibrillation Christopher B. Granger et al. · New England Journal of Medicine | 28 Aug 2011 | 9,001 |
| 12 | Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer Julie Renee Brahmer et al. · New England Journal of Medicine | 31 May 2015 | 8,632 |
| 13 | Integrated genomic analyses of ovarian carcinoma Debra Bell et al. · Nature | 28 Jun 2011 | 8,268 |
| 14 | Comprehensive genomic characterization defines human glioblastoma genes and core pathways Roger E. McLendon et al. · Nature | 4 Sep 2008 | 7,893 |
| 15 | Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Charles E. Murry, Robert B. Jennings, K A Reimer · Circulation | Nov 1986 | 7,857 |
| 16 | Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery Martin B. Leon et al. · New England Journal of Medicine | 20 Oct 2010 | 7,239 |
| 17 | Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis Daniel R. Rosen et al. · Nature | Mar 1993 | 7,116 |
| 18 | Glioma stem cells promote radioresistance by preferential activation of the DNA damage response Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature | 18 Oct 2006 | 6,478 |
| 19 | Neuroinflammation in Alzheimer's disease Michael Thomas Heneka et al. · The Lancet Neurology | 16 Mar 2015 | 6,318 |
| 20 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy | 2 Jan 2016 | 6,023 |
| 21 | A Clinical Trial of the Effects of Dietary Patterns on Blood Pressure Lawrence J. Appel, Thomas J. Moore, Eva Obarzanek et al. · New England Journal of Medicine | 17 Apr 1997 | 6,008 |
| 22 | Effectiveness of Antipsychotic Drugs in Patients with Chronic Schizophrenia Jeffrey Alan Lieberman, T. Scott Stroup, Joseph P. McEvoy et al. · New England Journal of Medicine | 19 Sep 2005 | 5,930 |
| 23 | Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia Shannon L. Maude et al. · New England Journal of Medicine | 31 Jan 2018 | 5,818 |
| 24 | The Warburg Effect: How Does it Benefit Cancer Cells? Maria V. Liberti, Jason W. Locasale · Trends in Biochemical Sciences | 5 Jan 2016 | 5,355 |
| 25 | Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management Steven Y. C. Tong, Joshua Saul Davis, Emily M. Eichenberger et al. · Clinical Microbiology Reviews | 27 May 2015 | 5,276 |
| 26 | The Somatic Genomic Landscape of Glioblastoma Cameron Brennan et al. · Cell | Oct 2013 | 5,261 |
| 27 | Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee A. MICHAEL PARFITT, Marc K. Drezner, Francis H. Glorieux et al. · Journal of Bone and Mineral Research | Dec 1987 | 5,049 |
| 28 | PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer Jing Li, Clifford Yen, Danny Liaw et al. · Science | 28 Mar 1997 | 4,843 |
| 29 | Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease Alison Goate et al. · Nature | 21 Feb 1991 | 4,701 |
| 30 | Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy Howard I. Scher, Karim S. Fizazi, Fred Saad et al. · New England Journal of Medicine | 15 Aug 2012 | 4,645 |
| 31 | Clinical Rating Systems for the Ankle-Hindfoot, Midfoot, Hallux, and Lesser Toes Harold B. Kitaoka, Ian James Alexander, Robert S. Adelaar et al. · Foot & Ankle International | Jul 1994 | 4,519 |
| 32 | Lipopolysaccharide Endotoxins Christian R.H. Raetz, Chris Whitfield · Annual Review of Biochemistry | Jun 2002 | 4,420 |
| 33 | The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction Richard C. Bump, Anders Mattiasson, Kari Bø et al. · American Journal of Obstetrics and Gynecology | Jul 1996 | 4,305 |
| 34 | Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease Robin P. Sherrington et al. · Nature | Jun 1995 | 4,080 |
| 35 | Features and uses of high-fidelity medical simulations that lead to effective learning: a BEME systematic review Saul Barry Issenberg, William C. McGaghie, EMIL R. PETRUSA et al. · Medical Teacher | 2005 | 3,976 |
| 36 | Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study Lisa A. Carey, Charles M. Perou, Chad Livasy et al. · JAMA | 6 Jun 2006 | 3,866 |
| 37 | Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice Vanessa K. Ridaura et al. · Science | 5 Sep 2013 | 3,861 |
| 38 | Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer Sunil Verma, David W. Miles, Luca Gianni et al. · New England Journal of Medicine | Oct 2012 | 3,859 |
| 39 | The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature | 5 Feb 2020 | 3,854 |
| 40 | Wnt signalling in stem cells and cancer Tannishtha Reya, Hans C. Clevers · Nature | 13 Apr 2005 | 3,705 |
| 41 | Identification of the breast cancer susceptibility gene BRCA2 Richard Wooster et al. · Nature | Dec 1995 | 3,687 |
| 42 | Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome Gregory G. Schwartz et al. · New England Journal of Medicine | 7 Nov 2018 | 3,654 |
| 43 | Dopamine Receptors: From Structure to Function Cristina Missale, Stuart Nash, Susan W. Robinson et al. · Physiological Reviews | 1998 | 3,654 |
| 44 | Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation William A. Zoghbi, David H Adams, Robert O. Bonow et al. · Journal of the American Society of Echocardiography | 14 Mar 2017 | 3,570 |
| 45 | The APACHE III Prognostic System William A. Knaus, Douglas P. Wagner, Elizabeth A. Draper et al. · CHEST Journal | Dec 1991 | 3,502 |
| 46 | Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations Robert H. Dworkin et al. · Journal of Pain | 13 Dec 2007 | 3,496 |
| 47 | High Frequency of Mutations of the PIK3CA Gene in Human Cancers Yardena Samuels, Zhenghe Wang, Alberto Bardelli et al. · Science | 15 Mar 2004 | 3,473 |
| 48 | SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES Irwin Fridovich · Annual Review of Biochemistry | Jun 1995 | 3,456 |
| 49 | Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature | 5 Feb 2020 | 3,360 |
| 50 | The Biology of Oxygen Radicals Irwin Fridovich · Science | 8 Sep 1978 | 3,349 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.