| 1 |
Biological insights from 108 schizophrenia-associated genetic loci
Stephan Ripke et al. · Nature
Open access297 authors |
Jul 2014 |
8,181 |
| 2 |
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
MAGIC et al. · Nature Genetics
Open access376 authors |
10 Oct 2010 |
2,999 |
| 3 |
Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry
Loïc Yengo, Julia Sidorenko, Kathryn E. Kemper et al. · Human Molecular Genetics
ReviewOpen access |
4 Aug 2018 |
2,612 |
| 4 |
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Hana Lango Allen et al. · Nature
Open access293 authors |
29 Sep 2010 |
2,063 |
| 5 |
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations
Swapan Mallick et al. · Nature
Open access |
20 Sep 2016 |
1,804 |
| 6 |
g:Profiler—a web-based toolset for functional profiling of gene lists from large-scale experiments
Jüri Reimand, Meelis Kull, Hedi Peterson et al. · Nucleic Acids Research
Open access |
3 May 2007 |
1,703 |
| 7 |
Population genomics of Bronze Age Eurasia
Morten E. Allentoft et al. · Nature
Open access |
9 Jun 2015 |
1,663 |
| 8 |
Ancient human genomes suggest three ancestral populations for present-day Europeans
Iosif Lazaridis et al. · Nature
Open access120 authors |
Sep 2014 |
1,497 |
| 9 |
Automatic clustering of orthologs and in-paralogs from pairwise species comparisons
Maido Remm, Christian E. V. Storm, Erik L. L. Sonnhammer · Journal of Molecular Biology
|
Dec 2001 |
1,211 |
| 10 |
Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans
Maanasa Raghavan et al. · Nature
Open access |
19 Nov 2013 |
1,041 |
| 11 |
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
MAGIC et al. · Nature Genetics
301 authors |
10 Oct 2010 |
965 |
| 12 |
Ancient human genome sequence of an extinct Palaeo-Eskimo
Morten Rasmussen et al. · Nature
Open access |
Feb 2010 |
882 |
| 13 |
Sex differences and hormonal effects on gut microbiota composition in mice
Elin Org, Margarete Mehrabian, Brian W. Parks et al. · Gut Microbes
Open access |
29 Jun 2016 |
838 |
| 14 |
An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia
Morten Rasmussen et al. · Science
Open access |
22 Sep 2011 |
817 |
| 15 |
The transcriptional landscape of age in human peripheral blood
Marjolein J. Peters et al. · Nature Communications
Open access137 authors |
22 Oct 2015 |
783 |
| 16 |
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Anubha Mahajan et al. · Nature Genetics
Open access354 authors |
May 2022 |
774 |
| 17 |
Beringian Standstill and Spread of Native American Founders
Erika Tamm et al. · PLoS ONE
Open access |
4 Sep 2007 |
707 |
| 18 |
A genomic history of Aboriginal Australia
Anna‐Sapfo Malaspinas et al. · Nature
Open access |
20 Sep 2016 |
702 |
| 19 |
Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior
Thorgeir Elís Thorgeirsson et al. · Nature Genetics
Open access |
25 Apr 2010 |
697 |
| 20 |
Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene
Shay Tzur, Saharon Rosset, Revital Shemer et al. · Human Genetics
Open access |
15 Jul 2010 |
658 |
| 21 |
Y-Chromosomal Diversity in Europe Is Clinal and Influenced Primarily by Geography, Rather than by Language
Zoë H. Rosser et al. · The American Journal of Human Genetics
Open access |
Dec 2000 |
619 |
| 22 |
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Ken Suzuki et al. · Nature
Open access369 authors |
19 Feb 2024 |
598 |
| 23 |
Early Divergent Strains of Yersinia pestis in Eurasia 5,000 Years Ago
Simon Rasmussen et al. · Cell
Open access |
Oct 2015 |
592 |
| 24 |
The genome of a Late Pleistocene human from a Clovis burial site in western Montana
Morten Rasmussen et al. · Nature
Open access |
11 Feb 2014 |
592 |
| 25 |
Genomic evidence for the Pleistocene and recent population history of Native Americans
Maanasa Raghavan et al. · Science
Open access101 authors |
22 Jul 2015 |
575 |
| 26 |
Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo
Margus Pooga, Ursel Soomets, Mattias Hällbrink et al. · Nature Biotechnology
|
Sep 1998 |
575 |
| 27 |
A new highly penetrant form of obesity due to deletions on chromosome 16p11.2
Robin G. Walters et al. · Nature
Open access |
Feb 2010 |
566 |
| 28 |
A “Copernican” Reassessment of the Human Mitochondrial DNA Tree from its Root
Doron M. Behar, Mannis van Oven, Saharon Rosset et al. · The American Journal of Human Genetics
Open access |
Apr 2012 |
559 |
| 29 |
Ancient DNA from the First European Farmers in 7500-Year-Old Neolithic Sites
Wolfgang Haak, Peter Forster, Barbara Bramanti et al. · Science
|
10 Nov 2005 |
556 |
| 30 |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
Cristian Pattaro et al. · Nature Communications
Open access700 authors |
21 Jan 2016 |
547 |
| 31 |
Phylogeographic Differentiation of Mitochondrial DNA in Han Chinese
Yong‐Gang Yao, Qing-Peng Kong, Hans-Jürgen Bandelt et al. · The American Journal of Human Genetics
Open access |
Mar 2002 |
540 |
| 32 |
Genetic Discontinuity Between Local Hunter-Gatherers and Central Europe’s First Farmers
Barbara Bramanti, Mark Thomas, Wolfgang Haak et al. · Science
|
3 Sep 2009 |
528 |
| 33 |
Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu
Liis Leitsalu, Toomas Haller, Tõnu Esko et al. · International Journal of Epidemiology
Open access |
11 Feb 2014 |
525 |
| 34 |
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
Cathy E. Elks et al. · Nature Genetics
ReviewOpen access174 authors |
21 Nov 2010 |
514 |
| 35 |
A recent bottleneck of Y chromosome diversity coincides with a global change in culture
Monika Karmin et al. · Genome Research
Open access100 authors |
13 Mar 2015 |
511 |
| 36 |
A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma
Maria Teresa Landi et al. · The American Journal of Human Genetics
Open access |
16 Oct 2009 |
510 |
| 37 |
Common variants in KCNN3 are associated with lone atrial fibrillation
Patrick T. Ellinor et al. · Nature Genetics
Open access |
21 Feb 2010 |
490 |
| 38 |
Genomic analyses inform on migration events during the peopling of Eurasia
Luca Pagani et al. · Nature
Open access |
20 Sep 2016 |
488 |
| 39 |
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer
Yufei Wang et al. · Nature Genetics
Open access |
Jun 2014 |
486 |
| 40 |
DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns
Kaie Lokk, Vijayachitra Modhukur, Balaji Rajashekar et al. · Genome biology
Open access |
Apr 2014 |
484 |
| 41 |
The Molecular Dissection of mtDNA Haplogroup H Confirms That the Franco-Cantabrian Glacial Refuge Was a Major Source for the European Gene Pool
Alessandro Achilli et al. · The American Journal of Human Genetics
Open access |
4 Oct 2004 |
468 |
| 42 |
New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing
Andreas Keller et al. · Nature Communications
Open access |
28 Feb 2012 |
468 |
| 43 |
The Dawn of Human Matrilineal Diversity
Doron M. Behar, Richard Villems, Himla Soodyall et al. · The American Journal of Human Genetics
Open access |
25 Apr 2008 |
465 |
| 44 |
Ancient DNA from European Early Neolithic Farmers Reveals Their Near Eastern Affinities
Wolfgang Haak, Oleg Pavlovich Balanovsky, Juan J. Sánchez et al. · PLoS Biology
Open access |
9 Nov 2010 |
457 |
| 45 |
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
LifeLines Cohort Study et al. · Nature Genetics
Open access226 authors |
11 Sep 2011 |
447 |
| 46 |
The genome-wide structure of the Jewish people
Doron M. Behar et al. · Nature
|
8 Jun 2010 |
443 |
| 47 |
Genetic Structure of Europeans: A View from the North–East
Mari Nelis et al. · PLoS ONE
Open access |
7 May 2009 |
437 |
| 48 |
Genomic insights into the peopling of the Southwest Pacific
Pontus Skoglund et al. · Nature
Open access |
30 Sep 2016 |
433 |
| 49 |
New gene functions in megakaryopoiesis and platelet formation
Christian Gieger et al. · Nature
Open access163 authors |
29 Nov 2011 |
429 |
| 50 |
The origins and spread of domestic horses from the Western Eurasian steppes
Pablo Librado et al. · Nature
Open access163 authors |
20 Oct 2021 |
424 |