| 1 |
Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast
Mette L. Skjoedt, Tim Snoek, Kanchana Rueksomtawin Kildegaard et al. · Nature Chemical Biology
|
19 Sep 2016 |
253 |
| 2 |
Metabolic engineering of Saccharomyces cerevisiae for de novo production of dihydrochalcones with known antioxidant, antidiabetic, and sweet tasting properties
Michael Eichenberger, Beata Joanna Lehka, Christophe Folly et al. · Metabolic Engineering
Open access |
31 Oct 2016 |
123 |
| 3 |
Oxidation and cyclization of casbene in the biosynthesis of Euphorbia factors from mature seeds of Euphorbia lathyris L.
Dan Luo, Roberta Callari, Britta Hamberger et al. · Proceedings of the National Academy of Sciences
Open access |
9 Aug 2016 |
99 |
| 4 |
Yeast artificial chromosomes employed for random assembly of biosynthetic pathways and production of diverse compounds in Saccharomyces cerevisiae
Michael Næsby et al. · Microbial Cell Factories
Open access |
13 Aug 2009 |
78 |
| 5 |
Discovery and Reconstitution of the Cycloclavine Biosynthetic Pathway—Enzymatic Formation of a Cyclopropyl Group
Dorota Jakubczyk, Lorenzo Caputi, Anaëlle Hatsch et al. · Angewandte Chemie International Edition
Open access |
25 Feb 2015 |
75 |
| 6 |
De novo biosynthesis of anthocyanins in Saccharomyces cerevisiae
Michael Eichenberger, Anders Hansson, David Fischer et al. · FEMS Yeast Research
Open access |
16 Apr 2018 |
74 |
| 7 |
Reconstruction of the biosynthetic pathway for the core fungal polyketide scaffold rubrofusarin in Saccharomyces cerevisiae
Peter Rugbjerg, Michael Næsby, Uffe Hasbro Mortensen et al. · Microbial Cell Factories
Open access |
4 Apr 2013 |
64 |
| 8 |
Yeast Synthetic Biology Platform Generates Novel Chemical Structures as Scaffolds for Drug Discovery
Jens Uwe Klein, Jonathan R. Heal, William D. O. Hamilton et al. · ACS Synthetic Biology
Open access |
16 Jan 2014 |
60 |
| 9 |
Improving heterologous production of phenylpropanoids in Saccharomyces cerevisiae by tackling an unwanted side reaction of Tsc13, an endogenous double bond reductase.
Beata Joanna Lehka, Michael Eichenberger, Walden Emil Bjørn-Yoshimoto et al. · FEMS Yeast Research
Open access |
9 Jan 2017 |
50 |
| 10 |
The important ergot alkaloid intermediate chanoclavine-I produced in the yeast Saccharomyces cerevisiae by the combined action of EasC and EasE from Aspergillus japonicus
Curt A. F. Nielsen, Christophe Folly, Anaëlle Hatsch et al. · Microbial Cell Factories
Open access |
11 Aug 2014 |
50 |
| 11 |
Indirect and direct routes to C-glycosylated flavones in Saccharomyces cerevisiae
Katherina García Vanegas, Arésu Bondrup Larsen, Michael Eichenberger et al. · Microbial Cell Factories
Open access |
9 Jul 2018 |
49 |
| 12 |
Exploiting the bioengineering versatility of lactobionic acid in targeted nanosystems and biomaterials
Saúl Alonso · Journal of Controlled Release
Open access |
24 Aug 2018 |
45 |
| 13 |
RNA-seq, de novo transcriptome assembly and flavonoid gene analysis in 13 wild and cultivated berry fruit species with high content of phenolics
Vera Thole et al. · BMC Genomics
Open access |
Dec 2019 |
44 |
| 14 |
Controlled nail delivery of a novel lipophilic antifungal agent using various modern drug carrier systems as well as in vitro and ex vivo model systems
Sandy Naumann, Jean‐Philippe Meyer, Andreas Kiesow et al. · Journal of Controlled Release
|
18 Feb 2014 |
44 |
| 15 |
Identification and Microbial Production of the Raspberry Phenol Salidroside that Is Active against Huntington’s Disease
Nicolai Kallscheuer et al. · PLANT PHYSIOLOGY
Open access |
5 Nov 2018 |
40 |
| 16 |
Dynamic Control of ERG20 and ERG9 Expression for Improved Casbene Production in Saccharomyces cerevisiae
Roberta Callari, Yvan Meier, Davide Ravasio et al. · Frontiers in Bioengineering and Biotechnology
Open access |
Nov 2018 |
28 |
| 17 |
Production of (S)-2-aminobutyric acid and (S)-2-aminobutanol in Saccharomyces cerevisiae
Nora Weber, Anaëlle Hatsch, Ludivine Labagnere et al. · Microbial Cell Factories
Open access |
23 Mar 2017 |
28 |
| 18 |
Effect of Pharmaceutical Interventions Targeting Thromboxane Receptors and Thromboxane Synthase in Cardiovascular and Renal Diseases
Kjell S. Sakaríassen, Pēteris Alberts, Pierre Fontana et al. · Future Cardiology
|
28 Aug 2009 |
26 |
| 19 |
Heavy isotope labeling and mass spectrometry reveal unexpected remodeling of bacterial cell wall expansion in response to drugs
Heiner Atze, Yucheng Liang, Jean‐Emmanuel Hugonnet et al. · eLife
Open access |
9 Jun 2022 |
25 |
| 20 |
On-chip microfluidic systems for determination of L-glutamate based on enzymatic recycling of substrate
Wanida Laiwattanapaisal, Julia N. Yakovleva, Martin Bengtsson et al. · Biomicrofluidics
Open access |
Mar 2009 |
22 |
| 21 |
BacHBerry: BACterial Hosts for production of Bioactive phenolics from bERRY fruits
Alexey Dudnik et al. · Phytochemistry Reviews
Open access |
8 Sep 2017 |
20 |
| 22 |
Production of Putative Diterpene Carboxylic Acid Intermediates of Triptolide in Yeast
Victor Forman, Roberta Callari, Christophe Folly et al. · Molecules
Open access |
13 Jun 2017 |
18 |
| 23 |
Improvement of whole-cell transamination with Saccharomyces cerevisiae using metabolic engineering and cell pre-adaptation
Nora Weber, Marie F. Gorwa‐Grauslund, Magnus Carlquist · Microbial Cell Factories
Open access |
3 Jan 2017 |
18 |
| 24 |
The dual thromboxane receptor antagonist and thromboxane synthase inhibitor EV‐077 is a more potent inhibitor of platelet function than aspirin
Pierre Fontana, Pēteris Alberts, Kjell S. Sakaríassen et al. · Journal of Thrombosis and Haemostasis
Open access |
21 Jul 2011 |
18 |
| 25 |
EV-077 in vitro inhibits platelet aggregation in type-2 diabetics on aspirin
Kjell S. Sakaríassen, Eti Alessandra Femia, Federico M. Daray et al. · Thrombosis Research
Open access |
5 Sep 2012 |
17 |
| 26 |
The internal initiation of translation in bovine viral diarrhea virus RNA depends on the presence of an RNA pseudoknot upstream of the initiation codon
Lorin Moes, Manfred Wirth · Virology Journal
Open access |
2007 |
15 |
| 27 |
The Natural Diyne-Furan Fatty Acid EV-086 Is an Inhibitor of Fungal Delta-9 Fatty Acid Desaturation with Efficacy in a Model of Skin Dermatophytosis
Philipp Knechtle, Melanie Diefenbacher, Katrine B. V. Greve et al. · Antimicrobial Agents and Chemotherapy
Open access |
5 Nov 2013 |
13 |
| 28 |
Biosynthesis of angelyl-CoA in Saccharomyces cerevisiae
Roberta Callari, David Fischer, Harald Heider et al. · Microbial Cell Factories
Open access |
12 May 2018 |
12 |
| 29 |
Pharmacodynamic effects of EV-077 in patients with diabetes mellitus and coronary artery disease on aspirin or clopidogrel monotherapy: results of an in vitro pilot investigation
Fabiana Rollini, Antonio Tello‐Montoliu, Ronakkumar Patel et al. · Journal of Thrombosis and Thrombolysis
|
13 Aug 2013 |
12 |
| 30 |
Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling
Genny Degani, Enrico Ragni, Pedro Botías et al. · BMC Genomics
Open access |
2 Jul 2016 |
10 |
| 31 |
Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial
Amanda Rao, David R. Briskey, Georgia Roche et al. · Frontiers in Aging
Open access |
19 Dec 2025 |
9 |
| 32 |
Single ascending oral dose pharmacokinetics and pharmacodynamics study of EV-077: the specific inhibitor of prostanoid- and isoprostane-induced cellular activation
Alesia A. Richardson, Kjell S. Sakaríassen, Jean‐Philippe Meyer et al. · European Journal of Clinical Pharmacology
|
19 Jul 2012 |
8 |
| 33 |
Increased availability of NADH in metabolically engineered baker’s yeast improves transaminase-oxidoreductase coupled asymmetric whole-cell bioconversion
Jan Dines Knudsen, Cecilia Hägglöf, Nora Weber et al. · Microbial Cell Factories
Open access |
15 Feb 2016 |
7 |
| 34 |
Pharmacodynamic effects of EV-077: results of an in vitro pilot investigation in healthy volunteers
Antonio Tello‐Montoliu, Fabiana Rollini, Bhaloo Desai et al. · Journal of Thrombosis and Thrombolysis
|
25 Aug 2012 |
7 |
| 35 |
Identification and characterization of phlorizin transporter from Arabidopsis thaliana and its application for phlorizin production in Saccharomyces cerevisiae
Zeinu Mussa Belew, Christoph Crocoll, Iben Møller‐Hansen et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
14 Aug 2020 |
5 |
| 36 |
Yeast-based assays for screening 11β-HSD1 inhibitors
Rosario Vanella, Roberta Callari, Anna A. Weston et al. · Microbial Cell Factories
Open access |
15 Mar 2016 |
2 |
| 37 |
Bäckerhefe Saccharomyces cerevisiae als universelle chemische Mikrofabrik
Jutta Heim, Thomas Ø Tange, Jens Uwe Klein · BIOspektrum
Open access |
Jun 2014 |
1 |