| 1 |
The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age‐Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults
Małgorzata Nita, Andrzej E. Grzybowski · Oxidative Medicine and Cellular Longevity
Open access |
2016 |
1,467 |
| 2 |
Indigenous and tribal peoples' health (The Lancet–Lowitja Institute Global Collaboration): a population study
Ian P S Anderson et al. · The Lancet
Open access |
26 Apr 2016 |
1,030 |
| 3 |
Advances in drug delivery systems, challenges and future directions
Tobechukwu Christian Ezike, Ugochukwu Solomon Okpala, Ufedo Lovet Onoja et al. · Heliyon
Open access |
Jun 2023 |
988 |
| 4 |
Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
Simon I Hay et al. · The Lancet
Open access2,780 authors |
Oct 2025 |
762 |
| 5 |
Molecular mechanism of heavy metals (Lead, Chromium, Arsenic, Mercury, Nickel and Cadmium) - induced hepatotoxicity – A review
Kaviyarasi Renu, Rituraj Chakraborty, Haritha Myakala et al. · Chemosphere
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30 Jan 2021 |
604 |
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Clinical Course and Outcome of Human Monkeypox in Nigeria
Dimie Ogoina, Michael Onyebuchi Iroezindu, Hendris Izibewule James et al. · Clinical Infectious Diseases
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11 Feb 2020 |
502 |
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Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
Mohsen Naghavi et al. · The Lancet
Open access2,463 authors |
Oct 2025 |
500 |
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Characterization of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low- and middle-income countries
Kirsty M. Sands et al. · Nature Microbiology
Open access |
29 Mar 2021 |
472 |
| 9 |
Global Retinoblastoma Presentation and Analysis by National Income Level
Global Retinoblastoma Study Group et al. · JAMA Oncology
Open access473 authors |
27 Feb 2020 |
382 |
| 10 |
Prevalence and Risk Factors for Diabetes Mellitus in Nigeria: A Systematic Review and Meta-Analysis
Andrew Enemako Uloko, Andrew E. Uloko, Baba M. Musa et al. · Diabetes Therapy
ReviewOpen access |
14 May 2018 |
363 |
| 11 |
The global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023
Lisa M Force et al. · The Lancet
Open access1,377 authors |
25 Sep 2025 |
330 |
| 12 |
Diabetes and peripheral artery disease: A review
David Olubukunmi Soyoye, Olugbenga Olusola Abiodun, Rosemary Temidayo Ikem et al. · World Journal of Diabetes
Open access |
4 Jun 2021 |
271 |
| 13 |
AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders
Vincenzo Salpietro et al. · Nature Communications
Open access239 authors |
12 Jul 2019 |
258 |
| 14 |
Diabetic foot care: Self reported knowledge and practice among patients attending three tertiary hospital in Nigeria
OO Desalu, FK Salawu, AK Jimoh et al. · Ghana Medical Journal
Open access |
23 Aug 2011 |
254 |
| 15 |
Natural Nanoparticles: A Particular Matter Inspired by Nature
Sharoon Griffin, Muhammad Irfan Masood, Muhammad Jawad Nasim et al. · Antioxidants
Open access |
29 Dec 2017 |
242 |
| 16 |
Breast cancer survival and survival gap apportionment in sub-Saharan Africa (ABC-DO): a prospective cohort study
Valerie McCormack, Fiona McKenzie, Milena Foerster et al. · The Lancet Global Health
Open access |
19 Aug 2020 |
236 |
| 17 |
When getting there is not enough: a nationwide cross‐sectional study of 998 maternal deaths and 1451 near‐misses in public tertiary hospitals in a low‐income country
OT Oladapo et al. · BJOG An International Journal of Obstetrics & Gynaecology
Open access |
14 May 2015 |
222 |
| 18 |
Germination as a bioprocess for enhancing the quality and nutritional prospects of legume proteins
Ikenna Christian Ohanenye, Apollinaire Tsopmo, Chukwunonso E.C.C. Ejike et al. · Trends in Food Science & Technology
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14 May 2020 |
218 |
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Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1
J. O. Clausen, Torben F. Hansen, Christian Bjørbæk et al. · The Lancet
Open access |
Aug 1995 |
214 |
| 20 |
Prospects of microalgae proteins in producing peptide-based functional foods for promoting cardiovascular health
Chukwunonso E.C.C. Ejike, Stephanie Anne Collins, Nileeka Balasuriya et al. · Trends in Food Science & Technology
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19 Nov 2016 |
194 |
| 21 |
Africa’s low COVID-19 mortality rate: A paradox?
Yakubu Lawal · International Journal of Infectious Diseases
Open access |
16 Oct 2020 |
175 |
| 22 |
Factors influencing the pattern of self-medication in an adult Nigerian population
Adedeji Olushola Afolabi · Annals of African Medicine
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2008 |
160 |
| 23 |
Predictors of lower extremity amputation in patients with diabetic foot ulcer: findings from MEDFUN, a multi‐center observational study
Ejiofor T. Ugwu, Olufunmilayo Adeleye, Ibrahim Gezawa et al. · Journal of Foot and Ankle Research
Open access |
2019 |
159 |
| 24 |
A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic
Ke Wang et al. · Nature Human Behaviour
Open access460 authors |
2 Aug 2021 |
156 |
| 25 |
Ligation of intersphincteric fistula tract (LIFT) in treatment of anal fistula: An updated systematic review, meta-analysis, and meta-regression of the predictors of failure
Sameh Hany Emile, Sualeh Muslim Khan, Adeyinka Adejumo et al. · Surgery
Review |
21 Oct 2019 |
149 |
| 26 |
Current sickle cell disease management practices in Nigeria
Najibah Aliyu Galadanci et al. · International Health
Open access |
10 Oct 2013 |
148 |
| 27 |
Effect of age, impaction types and operative time on inflammatory tissue reactions following lower third molar surgery
Seidu Adebayo Bello, Wasiu Lanre Adeyemo, Babatunde Olamide BAMGBOSE et al. · Head & Face Medicine
Open access |
28 Apr 2011 |
144 |
| 28 |
Prevalence, Awareness, Treatment and Control of Hypertension in Nigeria: Data from a Nationwide Survey 2017
Augustine N. Odili, Babangida Sylvester Chori, Benjamin Danladi et al. · Global Heart
Open access |
10 Jul 2020 |
143 |
| 29 |
Deubiquitinases (DUBs) and DUB inhibitors: a patent review
Pershang Farshi, Rahul R Deshmukh, Joseph O. Nwankwo et al. · Expert Opinion on Therapeutic Patents
Open access |
16 Jun 2015 |
136 |
| 30 |
Inequities in breast cancer treatment in sub-Saharan Africa: findings from a prospective multi-country observational study
Milena Foerster, Benjamin O. Anderson, Fiona McKenzie et al. · Breast Cancer Research
Open access |
13 Aug 2019 |
121 |
| 31 |
Chemometric analysis for pollution source identification and human health risk assessment of water resources in Ojoto Province, southeast Nigeria
Johnbosco C. Egbueri, Chukwuma N. Mgbenu · Applied Water Science
Open access |
23 Mar 2020 |
116 |
| 32 |
Influence of biochar aged in acidic soil on ecosystem engineers and two tropical agricultural plants
Ihuoma N. Anyanwu, Moses Nnaemeka Alo, Amos M. Onyekwere et al. · Ecotoxicology and Environmental Safety
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6 Feb 2018 |
116 |
| 33 |
Obstructive sleep apnea hypopnea syndrome
GC Mbata, JC Chukwuka · Annals of Medical and Health Sciences Research
Open access |
2012 |
112 |
| 34 |
Nanomaterials in Drug Delivery: Strengths and Opportunities in Medicine
Chinedu Ogbonnia Egwu, Chinyere Aloke, Kenneth T. Onwe et al. · Molecules
Open access |
31 May 2024 |
111 |
| 35 |
The impact of electronic health records on patient care and outcomes: A comprehensive review
Adekunle Oyeyemi Adeniyi, Jeremiah Olawumi Arowoogun, Rawlings Chidi et al. · World Journal of Advanced Research and Reviews
Open access |
26 Feb 2024 |
111 |
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Prevalence of Orofacial Clefts in Nigeria
Azeez Butali, Wasiu Lanre Adeyemo, Peter Anthony Mossey et al. · The Cleft Palate-Craniofacial Journal
Open access |
4 Apr 2013 |
111 |
| 37 |
Can Autologous Platelet-Rich Plasma Gel Enhance Healing After Surgical Extraction of Mandibular Third Molars?
Olufemi Ogundipe, Vincent Ifechukwukwu Ugboko, Folusho J. Owotade · Journal of Oral and Maxillofacial Surgery
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10 May 2011 |
110 |
| 38 |
From nature to nanotechnology: The interplay of traditional medicine, green chemistry, and biogenic metallic phytonanoparticles in modern healthcare innovation and sustainability
Abhijeet Vishnu Puri, Popat B Mohite, Swastika Maitra et al. · Biomedicine & Pharmacotherapy
Open access |
31 Dec 2023 |
107 |
| 39 |
Oral Health Inequalities between Rural and Urban Populations of the African and Middle East Region
Eyitope O. Ogunbodede, IA Kida, H.S. Madjapa et al. · Advances in Dental Research
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22 Jun 2015 |
107 |
| 40 |
Raw oil palm frond leaves as cost-effective substrate for cellulase and xylanase productions by Trichoderma asperellum UC1 under solid-state fermentation
Uchenna Regina Ezeilo, Chew Tin Lee, Fahrul ZAMAN HUYOP et al. · Journal of Environmental Management
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13 May 2019 |
104 |
| 41 |
Experimental, theoretical modeling and optimization of inhibition efficiency of pigeon pea leaf extract as anti-corrosion agent of mild steel in acid environment
Valentine Chikaodili Anadebe, Okechukwu D. Onukwuli, Monday Omotioma et al. · Materials Chemistry and Physics
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May 2019 |
101 |
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Drivers of advanced stage at breast cancer diagnosis in the multicountry A frican breast cancer – disparities in outcomes (ABC‐DO) study
Fiona McKenzie, Annelle Zietsman, Moses Galukande et al. · International Journal of Cancer
Open access |
2 Dec 2017 |
101 |
| 43 |
Enzymatic breakdown of lignocellulosic biomass: the role of glycosyl hydrolases and lytic polysaccharide monooxygenases
Uchenna Regina Ezeilo, Iffah Izzati Zakaria, Fahrul ZAMAN HUYOP et al. · Biotechnology & Biotechnological Equipment
Open access |
16 May 2017 |
101 |
| 44 |
Coronavirus disease 2019: Knowledge, attitude, and practice of pregnant women in a tertiary hospital in Abakaliki, southeast Nigeria
Chidebe Christian Anikwe, Christian O. Ogah, Ifeyinwa Helen Anikwe et al. · International Journal of Gynecology & Obstetrics
Open access |
Jul 2020 |
100 |
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Drug Prescription Pattern in a Nigerian Tertiary Hospital
Igbiks Tamuno, JO Fadare · Tropical Journal of Pharmaceutical Research
Open access |
12 Mar 2012 |
100 |
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Modifiable cardiovascular risk factors among apparently healthy adult Nigerian population - a cross sectional study
Mahmoud Umar Sani, Kolawole Wahab, Bashir O. Yusuf et al. · BMC Research Notes
Open access |
2010 |
99 |
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A global test of brief reappraisal interventions on emotions during the COVID-19 pandemic
Ke Wang et al.
PreprintOpen access450 authors |
17 Apr 2020 |
96 |
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Modeling thermal conductivity enhancement of metal and metallic oxide nanofluids using support vector regression
Ibrahim Olanrewaju Alade, Tajudeen Adeyinka Oyehan, Idris K. Popoola et al. · Advanced Powder Technology
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10 Nov 2017 |
96 |
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Hepatitis B virus infection amongst pregnant women in North-Eastern Nigeria- A call for action
Abdulfatai Bamidele Olokoba, FK Salawu, Ali Danburam et al. · Nigerian Journal of Clinical Practice
Open access |
2011 |
94 |
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Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation
Ademola C. Famurewa, Kaviyarasi Renu, Mohamed Ahmed Eladl et al. · Biomedicine & Pharmacotherapy
Open access |
4 Apr 2022 |
92 |