Most cited papers from Fondazione Pisa

Fondazione Pisa

What are the most cited papers from Fondazione Pisa?

The most cited paper from Fondazione Pisa is "Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer" (Alessandro Leonetti, Sugandhi Sharma, Roberta Minari et al., 2019), with 1,439 citations. Next come "Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial" (358) and "The role of alternative splicing in cancer: From oncogenesis to drug resistance" (333).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 60 papers. Every paper with more than 64 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer Alessandro Leonetti, Sugandhi Sharma, Roberta Minari et al. · British Journal of Cancer Open access	29 Sep 2019	1,439
2	Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial Isla S. Mackenzie et al. · The Lancet Open access	Nov 2020	358
3	The role of alternative splicing in cancer: From oncogenesis to drug resistance Rocco Sciarrillo, Anna Wojtuszkiewicz, Yehuda G. Assaraf et al. · Drug Resistance Updates Open access	28 Sep 2020	333
4	Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9 Ernesto Rodríguez, Kelly Boelaars, Kari R. Brown et al. · Nature Communications Open access	24 Feb 2021	322
5	Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity Carina B. Nava Lauson et al. · Cell Metabolism Open access	9 Mar 2023	296
6	High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue Alice Ly, Achim Buck, Benjamin Balluff et al. · Nature Protocols	14 Jul 2016	247
7	Deciphering the performance of macrophages in tumour microenvironment: a call for precision immunotherapy Belén Toledo, Linrui Zhu Chen, María Paniagua-Sancho et al. · Journal of Hematology & Oncology Open access	11 Jun 2024	221
8	Molecular basis and rationale for combining immune checkpoint inhibitors with chemotherapy in non-small cell lung cancer Alessandro Leonetti, Birgit M. M. Wever, Giulia Mazzaschi et al. · Drug Resistance Updates	Sep 2019	205
9	Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance Stella Cascioferro, Barbara Parrino, Daniela Carbone et al. · Journal of Medicinal Chemistry Open access	25 Mar 2020	204
10	Data-driven identification of prognostic tumor subpopulations using spatially mapped t-SNE of mass spectrometry imaging data Walid M. Abdelmoula, Benjamin Balluff, Sonja Englert et al. · Proceedings of the National Academy of Sciences Open access	10 Oct 2016	191
11	HGF/MET pathway aberrations as diagnostic, prognostic, and predictive biomarkers in human cancers Fatemeh Moosavi, Elisa Giovannetti, Luciano Saso et al. · Critical Reviews in Clinical Laboratory Sciences ReviewOpen access	12 Sep 2019	186
12	Therapeutic Strategies To Counteract Antibiotic Resistance in MRSA Biofilm‐Associated Infections Stella Cascioferro, Daniela Carbone, Barbara Parrino et al. · ChemMedChem Open access	14 Oct 2020	185
13	Linkage-Specific in Situ Sialic Acid Derivatization for N-Glycan Mass Spectrometry Imaging of Formalin-Fixed Paraffin-Embedded Tissues Stephanie Holst, Bram Heijs, Noortje de Haan et al. · Analytical Chemistry	4 May 2016	185
14	Ultra-High Mass Resolution MALDI Imaging Mass Spectrometry of Proteins and Metabolites in a Mouse Model of Glioblastoma Marialaura Dilillo, Rima Ait-Belkacem, Clara Esteve et al. · Scientific Reports Open access	29 Mar 2017	177
15	Applications and clinical trial landscape using Toll-like receptor agonists to reduce the toll of cancer Christian Diego Rolfo, Elisa Giovannetti, Pablo Martínez et al. · npj Precision Oncology Open access	8 Mar 2023	156
16	Harnessing the tumor microenvironment: targeted cancer therapies through modulation of epithelial-mesenchymal transition Antonino Glaviano et al. · Journal of Hematology & Oncology Open access	13 Jan 2025	149
17	Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling Rebecca S. Lamb, Gloria Bonuccelli, Béla Ózsvári et al. · Oncotarget Open access	28 Sep 2015	142
18	Sensitivity of microwave measurements to vegetation biomass and soil moisture content: a case study P. Ferrazzoli, S. Paloscia, Paolo Pampaloni et al. · IEEE Transactions on Geoscience and Remote Sensing	Jul 1992	142
19	Detection and localization of early- and late-stage cancers using platelet RNA Sjors G. J. G. In ‘t Veld et al. · Cancer Cell Open access116 authors	Sep 2022	137
20	Prognostically relevant periprocedural myocardial injury and infarction associated with percutaneous coronary interventions: a Consensus Document of the ESC Working Group on Cellular Biology of the Heart and European Association of Percutaneous Cardiovascular Interventions (EAPCI) Heerajnarain Bulluck et al. · European Heart Journal Open access	26 Apr 2021	137
21	Lactate Dehydrogenase and its clinical significance in pancreatic and thoracic cancers Annalisa Comandatore, Marika Frańczak, Ryszard Tomasz Smolenski et al. · Seminars in Cancer Biology Open access	9 Sep 2022	136
22	Doxycycline, an Inhibitor of Mitochondrial Biogenesis, Effectively Reduces Cancer Stem Cells (CSCs) in Early Breast Cancer Patients: A Clinical Pilot Study Cristian Scatena, Manuela Roncella, Antonello Di Paolo et al. · Frontiers in Oncology Open access	12 Oct 2018	135
23	Prospects of targeting PI3K/AKT/mTOR pathway in pancreatic cancer Motahareh Mortazavi, Fatemeh Moosavi, Miriam Martini et al. · Critical Reviews in Oncology/Hematology Open access	18 Jun 2022	130
24	De novo discovery of phenotypic intratumour heterogeneity using imaging mass spectrometry Benjamin Balluff, Christian Karl Frese, Stefan K. Maier et al. · The Journal of Pathology Open access	9 Sep 2014	130
25	Homotypic targeting and drug delivery in glioblastoma cells through cell membrane-coated boron nitride nanotubes Daniele De Pasquale, Attilio Marino, Christos Tapeinos et al. · Materials & Design Open access	23 Apr 2020	121
26	Heterogeneity and plasticity of cancer-associated fibroblasts in the pancreatic tumor microenvironment Lenka N.C. Boyd, Katarina D. Andini, Godefridus J. Peters et al. · Seminars in Cancer Biology Open access	18 Mar 2021	119
27	Multimodal Mass Spectrometry Imaging of N-Glycans and Proteins from the Same Tissue Section Bram Heijs, Stephanie Holst, Inge H. Briaire‐de Bruijn et al. · Analytical Chemistry	2 Jul 2016	110
28	Mass spectrometry imaging of amino neurotransmitters: a comparison of derivatization methods and application in mouse brain tissue Clara Esteve, Else A. Tolner, Reinald Shyti et al. · Metabolomics Open access	8 Jan 2016	110
29	The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies Btissame El Hassouni, Carlotta Granchi, Andrea Vallés‐Martí et al. · Seminars in Cancer Biology Open access	21 Aug 2019	107
30	Design and Performance of a Novel Interface for Combined Matrix-Assisted Laser Desorption Ionization at Elevated Pressure and Electrospray Ionization with Orbitrap Mass Spectrometry Mikhail E. Belov, Shane R. Ellis, Marialaura Dilillo et al. · Analytical Chemistry Open access	14 Jun 2017	107
31	Small cell lung cancer: Novel treatments beyond immunotherapy Job-Joris Meijer, Alessandro Leonetti, Giulia Airò et al. · Seminars in Cancer Biology Open access	11 May 2022	106
32	Fibroblasts in pancreatic cancer: molecular and clinical perspectives Rita Rebelo, Cristina P. R. Xavier, Elisa Giovannetti et al. · Trends in Molecular Medicine Review	24 Apr 2023	102
33	Photo thermal effect graphene detector featuring 105 Gbit s−1 NRZ and 120 Gbit s−1 PAM4 direct detection S. Marconi, M. A. Giambra, A. Montanaro et al. · Nature Communications Open access	5 Feb 2021	98
34	Targeting Peptides: The New Generation of Targeted Drug Delivery Systems Biagio Todaro, Elisa Ottalagana, Stefano Luin et al. · Pharmaceutics Open access	3 Jun 2023	96
35	GSK3β as a novel promising target to overcome chemoresistance in pancreatic cancer Camilla Pecoraro, Beatrice Faggion, Beatrice Balboni et al. · Drug Resistance Updates Open access	12 Aug 2021	93
36	The role of extracellular vesicles in the transfer of drug resistance competences to cancer cells Cristina P. R. Xavier, Dimas Carolina Belisario, Rita Rebelo et al. · Drug Resistance Updates Open access	5 Apr 2022	91
37	Cyclin Dependent Kinase-1 (CDK-1) Inhibition as a Novel Therapeutic Strategy against Pancreatic Ductal Adenocarcinoma (PDAC) Rosa Wijnen, Camilla Pecoraro, Daniela Carbone et al. · Cancers Open access	30 Aug 2021	89
38	Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development Patrizia Sarogni, Orazio Palumbo, Adele Servadio et al. · Journal of Experimental & Clinical Cancer Research Open access	Mar 2019	87
39	Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer Daniela Massihnia, Amir Avan, Niccola Funel et al. · Journal of Hematology & Oncology Open access	6 Jan 2017	87
40	Mass Spectrometry Imaging, Laser Capture Microdissection, and LC-MS/MS of the Same Tissue Section Marialaura Dilillo, Davide Pellegrini, Rima Ait-Belkacem et al. · Journal of Proteome Research	25 Jun 2017	85
41	PTEN Alterations as a Potential Mechanism for Tumor Cell Escape from PD-1/PD-L1 Inhibition Daniele Cretella, Graziana Digiacomo, Elisa Giovannetti et al. · Cancers Open access	6 Sep 2019	84
42	MicroRNAs as a drug resistance mechanism to targeted therapies in EGFR-mutated NSCLC: Current implications and future directions Alessandro Leonetti, Yehuda G. Assaraf, Paraskevi Danai Veltsista et al. · Drug Resistance Updates	28 Nov 2018	84
43	Sodium‐glucose co‐transporter ( SGLT )2 and SGLT1 renal expression in patients with type 2 diabetes Anna Solini, Chiara Rossi, Chiara Maria Mazzanti et al. · Diabetes Obesity and Metabolism	17 Apr 2017	82
44	Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells Omidreza Firuzi, Pei Pei, Btissame El Hassouni et al. · Cancers Open access	8 May 2019	80
45	Diagnostic accuracy and added value of blood-based protein biomarkers for pancreatic cancer: a meta-analysis of aggregate and individual participant data Lenka N.C. Boyd, Mahsoem Ali, Mariska Leeflang et al. · EClinicalMedicine ReviewOpen access	25 Nov 2022	78
46	Automatic Generic Registration of Mass Spectrometry Imaging Data to Histology Using Nonlinear Stochastic Embedding Walid M. Abdelmoula, Karolina Škrášková, Benjamin Balluff et al. · Analytical Chemistry	18 Aug 2014	77
47	CXCL12α/SDF‐1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals Samuele Negro, Francesca Lessi, Elisa Duregotti et al. · EMBO Molecular Medicine Open access	30 May 2017	74
48	Gene editing of DNAH11 restores normal cilia motility in primary ciliary dyskinesia Michele Lai, Massimo Pifferi, ANDREW J. BUSH et al. · Journal of Medical Genetics	4 Jan 2016	74
49	Brain-targeted enzyme-loaded nanoparticles: A breach through the blood-brain barrier for enzyme replacement therapy in Krabbe disease Ambra Del Grosso, Marianna Galliani, Lucia Angella et al. · Science Advances Open access	Nov 2019	72
50	2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent staphylococcal biofilm inhibitors Stella Cascioferro, Barbara Parrino, Giovanna Li Petri et al. · European Journal of Medicinal Chemistry	10 Feb 2019	72

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.