Institution · Gedeon Richter (Hungary)
Most cited papers from Gedeon Richter (Hungary)
What are the most cited papers from Gedeon Richter (Hungary)?
The most cited paper from Gedeon Richter (Hungary) is "The influence of lead discovery strategies on the properties of drug candidates" (György Miklós Keserű, Gergely M. Makara, 2009), with 633 citations. Next come "Finding the sweet spot: the role of nature and nurture in medicinal chemistry" (421) and "Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist–Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile" (373).
Showing 50 of 60 papers. Every paper with more than 102 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | The influence of lead discovery strategies on the properties of drug candidates György Miklós Keserű, Gergely M. Makara · Nature Reviews Drug Discovery | 27 Feb 2009 | 633 |
| 2 | Finding the sweet spot: the role of nature and nurture in medicinal chemistry Michael M. Hann, György Miklós Keserű · Nature Reviews Drug Discovery | 30 Apr 2012 | 421 |
| 3 | Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist–Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile Béla Kiss, Attila Horváth, Zsolt Némethy et al. · Journal of Pharmacology and Experimental Therapeutics | 21 Jan 2010 | 373 |
| 4 | Cariprazine versus risperidone monotherapy for treatment of predominant negative symptoms in patients with schizophrenia: a randomised, double-blind, controlled trial György Németh, I. Laszlovszky, Pál Czobor et al. · The Lancet | 7 Feb 2017 | 357 |
| 5 | Reserve of Right Ventricular-Arterial Coupling in the Setting of Chronic Overload Khodr Tello, Antonia Dalmer, Jens Axmann et al. · Circulation Heart Failure | 2019 | 264 |
| 6 | Hit discovery and hit-to-lead approaches György Miklós Keserű, Gergely M. Makara · Drug Discovery Today | 18 Jul 2006 | 258 |
| 7 | Fast liquid chromatography: The domination of core?shell and very fine particles Szabolcs Fekete, Erzsbet Olh, Jenő Fekete · Journal of Chromatography A | 23 Sep 2011 | 249 |
| 8 | Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood–brain barrier penetration models Éva Hellinger, Szilvia Veszelka, Andrea E. Tóth et al. · European Journal of Pharmaceutics and Biopharmaceutics | 11 Aug 2012 | 241 |
| 9 | An evaluation of the safety and efficacy of cariprazine in patients with acute exacerbation of schizophrenia: A phase II, randomized clinical trial Suresh Durgam, Anju Starace, Dayong Li et al. · Schizophrenia Research | 10 Jan 2014 | 194 |
| 10 | New Celecoxib Derivatives as Anti-Inflammatory Agents György Szabó, Itzhak Fischer, Ágnes Kis-Varga et al. · Journal of Medicinal Chemistry | 12 Dec 2007 | 193 |
| 11 | Effect of cariprazine across the symptoms of mania in bipolar I disorder: Analyses of pooled data from phase II/III trials Eduard Vieta, Suresh Durgam, Kaifeng Lu et al. · European Neuropsychopharmacology | 5 Sep 2015 | 193 |
| 12 | Long-term safety and tolerability of cariprazine as adjunctive therapy in major depressive disorder Eduard Vieta, Willie R. Earley, Maria Victoria Burgess et al. · International Clinical Psychopharmacology | 6 Dec 2018 | 191 |
| 13 | Skin–PAMPA: A new method for fast prediction of skin penetration Bálint Sinkó, Teresa Garrigues, György Tibor Balogh et al. · European Journal of Pharmaceutical Sciences | 2 Feb 2012 | 185 |
| 14 | Efficacy and Safety of Cariprazine in Acute Exacerbation of Schizophrenia John Michael Kane, Stephen R. Zukin, Yao Wang et al. · Journal of Clinical Psychopharmacology | 13 Jun 2015 | 180 |
| 15 | Long-term effects of cariprazine exposure on dopamine receptor subtypes Yong Kee Choi, Nika Adham, Béla Kiss et al. · CNS Spectrums | 8 Nov 2013 | 179 |
| 16 | Integrative molecular bioinformatics study of human adrenocortical tumors: microRNA, tissue-specific target prediction, and pathway analysis Zsófia Tömböl, Péter Márton Szabó, Viktor Molnár et al. · Endocrine Related Cancer | 22 Jun 2009 | 176 |
| 17 | Cariprazine in Acute Exacerbation of Schizophrenia Suresh Durgam, Andrew J. Cutler, Kaifeng Lu et al. · The Journal of Clinical Psychiatry | 21 Dec 2015 | 168 |
| 18 | Comparative study of new shell-type, sub-2μm fully porous and monolith stationary phases, focusing on mass-transfer resistance Erzsébet Oláh, Szabolcs Fekete, Jenő Fekete et al. · Journal of Chromatography A | 3 Apr 2010 | 167 |
| 19 | Impact of Lipophilic Efficiency on Compound Quality Ákos Tarcsay, Kinga Nyíri, György Miklós Keserű · Journal of Medicinal Chemistry | 9 Jan 2012 | 164 |
| 20 | Semiempirical AM1 electrostatic potentials and AM1 electrostatic potential derived charges: A comparison with ab initio values György G. Ferenczy, Christopher Arthur Reynolds, W. Graham Richards · Journal of Computational Chemistry | Mar 1990 | 161 |
| 21 | Alcohol Related Changes in Regulation of NMDA Receptor Functions József Nagy · Current Neuropharmacology | Mar 2008 | 155 |
| 22 | Preparation and Applications of Pentafluorophenyl Esters of 9-Fluorenylmethyloxycarbonyl Amino Acids for Peptide Synthesis Lajos KISFALUDY, István Schön · Synthesis | 1983 | 154 |
| 23 | Tumor Volume Estimation and Quasi-Continuous Administration for Most Effective Bevacizumab Therapy Johanna Sápi, Levente Kovács, Dániel András Drexler et al. · PLoS ONE | 5 Nov 2015 | 152 |
| 24 | Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents István Gyertyán, Béla Kiss, Katalin Sághy et al. · Neurochemistry International | 21 Jul 2011 | 151 |
| 25 | Incorporating small molecules or biologics into nanofibers for optimized drug release: A review István Sebe, Péter Szabó, Barnabás Kállai-Szabó et al. · International Journal of Pharmaceutics | 22 Aug 2015 | 146 |
| 26 | Electrophysiological studies with a 2,3-benzodiazepine muscle relaxant: GYKI 52466 István Tarnawa, Sándor Farkas, Pál Berzsenyi et al. · European Journal of Pharmacology | Aug 1989 | 144 |
| 27 | Determination of biogenic amines by capillary electrophoresis Ágnes Kovács, Lívia Simon‐Sarkadi, Katalin Ganzler · Journal of Chromatography A | Mar 1999 | 142 |
| 28 | Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport Szilvia Veszelka, András Tóth, Fruzsina R. Walter et al. · Frontiers in Molecular Neuroscience | 22 May 2018 | 140 |
| 29 | Contributions of Molecular Properties to Drug Promiscuity Ákos Tarcsay, György Miklós Keserű · Journal of Medicinal Chemistry | 15 Jan 2013 | 139 |
| 30 | Peripheral GABAergic mechanisms Sándor L. Erdö · Trends in Pharmacological Sciences | 1985 | 139 |
| 31 | Multisteric TRPV1 nocisensor: a target for analgesics Janós Szolcsányi, Sándor Zoltán · Trends in Pharmacological Sciences | 12 Oct 2012 | 139 |
| 32 | Role of sodium channel inhibition in neuroprotection: effect of vinpocetine Péter Bönöczk, Balázs Zoltán Gulyás, Vera Ádám‐Vizi et al. · Brain Research Bulletin | Oct 2000 | 135 |
| 33 | Thermodynamics guided lead discovery and optimization György G. Ferenczy, György Miklós Keserű · Drug Discovery Today | 31 Aug 2010 | 135 |
| 34 | The importance and the challenges of impurity profiling in modern pharmaceutical analysis Sándor Gǒrög · TrAC Trends in Analytical Chemistry | 8 Jul 2006 | 132 |
| 35 | Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [11C]-(+)-PHNO Ragy R. Girgis, Mark Slifstein, Deepak Cyril D’Souza et al. · Psychopharmacology | 15 Aug 2016 | 131 |
| 36 | Transendothelial Electrical Resistance Measurement across the Blood–Brain Barrier: A Critical Review of Methods Judit P. Vigh, András Kincses, Burak Ozgür et al. · Micromachines | 11 Jun 2021 | 130 |
| 37 | The efficacy and tolerability of cariprazine in acute mania associated with bipolar I disorder: a phase II trial Suresh Durgam, Anju Starace, Dayong Li et al. · Bipolar Disorders | 24 Jul 2014 | 130 |
| 38 | Virtual Fragment Docking by Glide: a Validation Study on 190 Protein−Fragment Complexes Márk Sándor, Robert S. Kiss, György Miklós Keserű · Journal of Chemical Information and Modeling | 11 May 2010 | 129 |
| 39 | Dopamine D3 receptor antagonists improve the learning performance in memory-impaired rats Judit Laszy, I. Laszlovszky, István Gyertyán · Psychopharmacology | 23 Dec 2004 | 128 |
| 40 | Cariprazine in the treatment of acute mania in bipolar I disorder: A double-blind, placebo-controlled, Phase III trial Gary S. Sachs, William M. Greenberg, Anju Starace et al. · Journal of Affective Disorders | 24 Nov 2014 | 127 |
| 41 | Validation and Quality Assurance of Planar Chromatographic Procedures in Pharmaceutical Analysis Katalin Ferenczi-Fodor, Zoltán Végh, A. Nagy-Turák et al. · Journal of AOAC International | Jul 2001 | 125 |
| 42 | Naturally occurring deuterium is essential for the normal growth rate of cells Gábor Somlyai, Gábor Jancsó, György Jákli et al. · FEBS Letters | 8 Feb 1993 | 124 |
| 43 | A High Throughput Luminescent Assay for Glycogen Synthase Kinase-3 β Inhibitors Andrea Baki, Attila Bielik, László Milán Molnár et al. · Assay and Drug Development Technologies | Feb 2007 | 124 |
| 44 | Linear and cyclic N‐terminal galanin fragments and analogs as ligands at the hypothalamic galanin receptor TUT LAND, OLO LANGEL, Miklós Löw et al. · International journal of peptide & protein research | Sep 1991 | 122 |
| 45 | Efficacy and Safety of Low- and High-Dose Cariprazine in Acute and Mixed Mania Associated With Bipolar I Disorder Joseph R. Calabrese, Paul E. Keck, Anju Starace et al. · The Journal of Clinical Psychiatry | 25 Nov 2014 | 121 |
| 46 | The efficacy of cariprazine in negative symptoms of schizophrenia: Post hoc analyses of PANSS individual items and PANSS-derived factors Wolfgang Fleischhacker, Silvana Galderisi, I. Laszlovszky et al. · European Psychiatry | 7 Feb 2019 | 117 |
| 47 | Eburnamine derivatives and the brain Ádám Vas, Balázs Zoltán Gulyás · Medicinal Research Reviews | 12 Sep 2005 | 116 |
| 48 | Enantiomeric derivatization for biomedical chromatography Sándor Gǒrög, M. Gazdag · Journal of Chromatography B Biomedical Sciences and Applications | Sep 1994 | 114 |
| 49 | Validation of thin layer and high performance thin layer chromatographic methods Bernd Renger, Zoltán Végh, Katalin Ferenczi-Fodor · Journal of Chromatography A | 28 Jan 2011 | 113 |
| 50 | Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods György Miklós Keserű · Bioorganic & Medicinal Chemistry Letters | 30 Jun 2003 | 112 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.