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Most cited papers from Genex Systems (United States)

What are the most cited papers from Genex Systems (United States)?

The most cited paper from Genex Systems (United States) is "Minimum information about a microarray experiment (MIAME)—toward standards for microarray data" (Alvis Brāzma et al., 2001), with 4,140 citations. Next come "Single-Chain Antigen-Binding Proteins" (1,508) and "Insights into human genetic variation and population history from 929 diverse genomes" (1,112).

Showing 50 of 59 papers. Every paper with more than 55 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Minimum information about a microarray experiment (MIAME)—toward standards for microarray data Alvis Brāzma et al. · Nature Genetics Dec 2001 4,140
2 Single-Chain Antigen-Binding Proteins Robert E. Bird, Karl D. Hardman, James W. Jacobson et al. · Science 21 Oct 1988 1,508
3 Insights into human genetic variation and population history from 929 diverse genomes Anders Bergström et al. · Science Open access 19 Mar 2020 1,112
4 Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris Frances J.D. Smith, Alan David Irvine, Ana Terron-Kwiatkowski et al. · Nature Genetics 29 Jan 2006 1,044
5 A Novel, Highly Stable Fold of the Immunoglobulin Binding Domain of Streptococcal Protein G Angela M. Gronenborn, David R. Filpula, Nina Z. Essig et al. · Science 9 Aug 1991 832
6 The 2.6-A crystal structure of Pseudomonas putida cytochrome P-450. T.L. Poulos, Barry C. Finzel, IRWIN C. GUNSALUS et al. · Journal of Biological Chemistry Open access Dec 1985 828
7 Adaptation and validation of the ACMG/AMP variant classification framework for MYH7-associated inherited cardiomyopathies: recommendations by ClinGen’s Inherited Cardiomyopathy Expert Panel Melissa Kelly et al. · Genetics in Medicine Open access 4 Jan 2018 383
8 Missense Mutations in GJB2 Encoding Connexin-26 Cause the Ectodermal Dysplasia Keratitis-Ichthyosis-Deafness Syndrome Gabriele Richard, Fatima Rouan, Colin Eric Willoughby et al. · The American Journal of Human Genetics Open access May 2002 375
9 A high-density consensus map of barley linking DArT markers to SSR, RFLP and STS loci and agricultural traits Peter Wenzl et al. · BMC Genomics Open access 12 Aug 2006 368
10 In Vivo Tumor Targeting of a Recombinant Single-Chain Antigen-Binding Protein David M. Colcher, Robert E. Bird, Mario Roselli et al. · JNCI Journal of the National Cancer Institute 18 Jul 1990 303
11 Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells Young-hua Xu, Shunsuke Ishii, Adrian Clark et al. · Nature Jun 1984 296
12 Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV‐1‐regulated protein gp34. Peter R. Baum, Richard B. Gayle, Fred Ramsdell et al. · The EMBO Journal Open access Sep 1994 286
13 Site-directed mutagenesis and the role of the oxyanion hole in subtilisin. Philip N. Bryan, Michael W. Pantoliano, Steven Quill et al. · Proceedings of the National Academy of Sciences Open access Jun 1986 241
14 Structure of the Human Interleukin-2 Receptor Gene Warren J. Leonard, Joel M. Depper, Minoru I. Kanehisa et al. · Science 8 Nov 1985 219
15 CRYSTAL STRUCTURES OF METYRAPONE-AND PHENYLIMIDAZOLE-INHIBITED COMPLEXES OF CYTOCHROME P450-CAM T.L. Poulos, Andrew J. Howard · Biochemistry Dec 1987 215
16 Structure and Evolution Donald R. Helinski, Stanley N. Cohen, Don B. Clewell et al. Book chapter 1985 206
17 Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding Michael W. Pantoliano, Marc D. Whitlow, Jay F. Wood et al. · Biochemistry Sep 1989 203
18 A metal‐mediated hydride shift mechanism for xylose isomerase based on the 1.6 Å Streptomycs rubiginosus structure with xylitol and D ‐xylose Marc D. Whitlow, Andrew J. Howard, Barry C. Finzel et al. · Proteins Structure Function and Bioinformatics Mar 1991 198
19 pH-Dependent Processes in Protein James B. Matthew, Frank R. N. Gurd, Bertrand E. García‐Moreno et al. · Critical Reviews in Biochemistry and Molecular Biology Review 1985 182
20 The nucleotide sequence of the tyrosinase gene from Streptomyces antibioticus and characterization of the gene product Valerie S. Bernan, David R. Filpula, Wayne K. Herber et al. · Gene 1985 170
21 The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case Michael W. Pantoliano, Marc D. Whitlow, Jay F. Wood et al. · Biochemistry Nov 1988 169
22 Protein Engineering Kevin M. Ulmer · Science 11 Feb 1983 166
23 Dominant Positive and Negative Selection Using a Hygromycin Phosphotransferase-Thymidine Kinase Fusion Gene Stephen D. Lupton, Laurie L. Brunton, Victoria A. Kalberg et al. · Molecular and Cellular Biology Open access Jun 1991 164
24 Clinical Applications of Three-Dimensional Photography in Breast Surgery Greg M. Galdino, Maurice Y. Nahabedian, Michael F. Chiaramonte et al. · Plastic & Reconstructive Surgery Jul 2002 163
25 Testing and Analysis of Precast Columns with Grouted Sleeve Connections and Shifted Plastic Hinging Zachary B. Haber, Kevin R. Mackie, Haider M. Al-Jelawy · Journal of Bridge Engineering Open access 11 Aug 2017 150
26 Dominant Mutations in KAT6A Cause Intellectual Disability with Recognizable Syndromic Features Emma Tham, Anna Lindstrand, Avni Santani et al. · The American Journal of Human Genetics Open access 26 Feb 2015 147
27 Conformational stability, folding, and ligand-binding affinity of single-chain Fv immunoglobulin fragments expressed in Escherichia coli Michael W. Pantoliano, Robert E. Bird, Syd Johnson et al. · Biochemistry Oct 1991 146
28 Structural and Functional Repetition in a Marine Mussel Adhesive Protein David R. Filpula, Shwu‐Maan Lee, Rebecca P. Link et al. · Biotechnology Progress May 1990 146
29 Proteases of enhanced stability: Characteization of a thermostable variant of subtilisin Philip N. Brayan, Michele L. Rollence, Michael W. Pantoliano et al. · Proteins Structure Function and Bioinformatics Apr 1986 146
30 CHARGE (Coloboma, Heart Defect, Atresia Choanae, Retarded Growth and Development, Genital Hypoplasia, Ear Anomalies/Deafness) Syndrome and Chromosome 22q11.2 Deletion Syndrome: A Comparison of Immunologic and Nonimmunologic Phenotypic Features Soma C. Jyonouchi, Donna M. McDonald‐McGinn, Sherri J. Bale et al. · PEDIATRICS Open access 27 Apr 2009 129
31 Protein-based medical adhesives Robert L. Strausberg, Rebecca P. Link · Trends in biotechnology 1990 124
32 De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome Jung‐Hyun Kim et al. · The American Journal of Human Genetics Open access 22 Aug 2016 122
33 Unscheduled DNA synthesis tests Ann D. Mitchell, Daniel A. Casciano, Martin L. Meltz et al. · Mutation Research/Reviews in Genetic Toxicology Dec 1983 119
34 An evaluation of the Escherichia coli WP2 and WP2uvrA reverse mutation assay David Brusick, Vincent F. Simmon, Herbert S. Rosenkranz et al. · Mutation Research/Reviews in Genetic Toxicology Sep 1980 108
35 Vitamin C–squalene bioconjugate promotes epidermal thickening and collagen production in human skin Ruxandra Gref, Claudine Deloménie, Andrei Maksimenko et al. · Scientific Reports Open access 9 Oct 2020 99
36 Secretion of human serum albumin from Bacillus subtilis Charles W. Saunders, Brian J. Schmidt, Richard L. Mallonee et al. · Journal of Bacteriology Open access Jul 1987 97
37 Molecular cloning of human ornithine aminotransferase mRNA. George Inana, Shiroh Totsuka, T. Michael Redmond et al. · Proceedings of the National Academy of Sciences Open access Mar 1986 94
38 Chloramphenicol-inducible gene expression in Bacillus subtilis Elizabeth J. Duvall, Donna Marie Williams, Susan T. Lovett et al. · Gene Oct 1983 94
39 Activity situations on an Alzheimer's disease special care unit and resident environmental interaction, time use, and affect Wendy H. Wood, Shelly L. Harris, Melinda Snider et al. · American Journal of Alzheimer s Disease & Other Dementias® Open access Mar 2005 93
40 An overview of short‐term tests for the mutagenic and carcinogenic potential of pesticides Michael D. Waters, Vincent F. Simmon, R. Valencia et al. · Journal of Environmental Science and Health Part B 1980 92
41 Manufacture of l-amino acids with bioreactors Bruce K. Hamilton, Humg‐Yu Hsiao, Wayne E. Swann et al. · Trends in biotechnology Review Mar 1985 90
42 Wild Chimpanzees Infected with 5PlasmodiumSpecies Marco Kaiser, Anna Löwa, Markus Ulrich et al. · Emerging infectious diseases Open access 2 Nov 2010 88
43 Single-chain Fv proteins and their fusion proteins Marc D. Whitlow, David R. Filpula · Methods Apr 1991 87
44 Design and Application of Microsatellite Marker Panels for Semiautomated Genotyping of Rice (Oryza sativa L.) Jason R. Coburn, Svetlana V. Temnykh, E. M. Paul et al. · Crop Science Nov 2002 87
45 Flexural Behavior and Design of Ultrahigh-Performance Concrete Beams Rafic G. El-Helou, Benjamin A. Graybeal · Journal of Structural Engineering Open access 28 Jan 2022 82
46 A Recurrent De Novo PACS2 Heterozygous Missense Variant Causes Neonatal-Onset Developmental Epileptic Encephalopathy, Facial Dysmorphism, and Cerebellar Dysgenesis Heather E. Olson et al. · The American Journal of Human Genetics Open access 12 Apr 2018 81
47 Simulation of the Landfall of the Deepwater Horizon Oil on the Shorelines of the Gulf of Mexico Michel C. Boufadel, Ali Abdollahi-Nasab, Xiaolong Geng et al. · Environmental Science & Technology Open access 28 Jul 2014 79
48 Isolation of cDNA and genomic DNA clones encoding type II collagen Marian F. Young, Gabriel Vögeli, Anne Marie Nunez et al. · Nucleic Acids Research Open access 1984 76
49 Ligands for the receptor tyrosine kinases hek and elk: isolation of cDNAs encoding a family of proteins. Kozlosky Cj, Eugene Maraskovsky, McGrew Jt et al. · PubMed 19 Jan 1995 71
50 X-ray Crystallographic Studies of Candida albicans Dihydrofolate Reductase Marc D. Whitlow, Andrew J. Howard, David B. Stewart et al. · Journal of Biological Chemistry Open access Nov 1997 71

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.