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Institution · Hovione (Portugal)

Most cited papers from Hovione (Portugal)

What are the most cited papers from Hovione (Portugal)?

The most cited paper from Hovione (Portugal) is "Fundamental analysis of particle formation in spray drying" (João Vicente, João F. Pinto, José Cardoso de Menezes et al., 2013), with 254 citations. Next come "Molecularly-imprinted chloramphenicol sensor with laser-induced graphene electrodes" (211) and "Genotoxic Impurities in Pharmaceutical Manufacturing: Sources, Regulations, and Mitigation" (207).

Showing 50 of 59 papers. Every paper with more than 13 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Fundamental analysis of particle formation in spray drying João Vicente, João F. Pinto, José Cardoso de Menezes et al. · Powder Technology 5 Jul 2013 254
2 Molecularly-imprinted chloramphenicol sensor with laser-induced graphene electrodes Ana Rita Aires Cardoso, Ana C. Marques, Lídia Santos et al. · Biosensors and Bioelectronics Open access 14 Oct 2018 211
3 Genotoxic Impurities in Pharmaceutical Manufacturing: Sources, Regulations, and Mitigation György Székely, Miriam C. Amores de Sousa, Marco Gil et al. · Chemical Reviews Review 7 Aug 2015 207
4 Organic solvent nanofiltration: A platform for removal of genotoxins from active pharmaceutical ingredients György Székely, João Bandarra, William Heggie et al. · Journal of Membrane Science 8 Jul 2011 171
5 Transition metal complexes containing hydrazine and substituted hydrazines Brian T. Heaton, Chacko Jacob, Philip C. Bulman Page · Coordination Chemistry Reviews Sep 1996 110
6 Microfluidic production of mRNA-loaded lipid nanoparticles for vaccine applications Carolina Salomão Lopes, Joana Cristóvão, Vânia Silvério et al. · Expert Opinion on Drug Delivery Open access 3 Oct 2022 83
7 Spray-Drying Technology Dave A. Miller, Marco Gil · AAPS advances in the pharmaceutical sciences series Book chapter 31 Oct 2011 81
8 Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol Cláudia Bento, Marianna Katz, Maria M. M. Santos et al. · Organic Process Research & Development Open access Apr 2024 69
9 Environmental and economic analysis for selection and engineering sustainable API degenotoxification processes György Székely, Marco Gil, Börje Sellergren et al. · Green Chemistry 26 Oct 2012 63
10 Spray dried powders for nasal delivery: Process and formulation considerations Patrícia Henriques, Ana C. Fortuna, Slavomíra Doktorovová · European Journal of Pharmaceutics and Biopharmaceutics 11 May 2022 62
11 A hybrid approach to reach stringent low genotoxic impurity contents in active pharmaceutical ingredients: Combining molecularly imprinted polymers and organic solvent nanofiltration for removal of 1,3-diisopropylurea György Székely, João Bandarra, William Heggie et al. · Separation and Purification Technology 28 Oct 2011 62
12 Development of a molecularly imprinted polymer for a pharmaceutical impurity in supercritical CO2: Rational design using computational approach Raquel Viveiros, K A Karim, Sergey A. Piletsky et al. · Journal of Cleaner Production 4 Sep 2017 58
13 Spray Freeze Drying of Biologics: A Review and Applications for Inhalation Delivery Susana Farinha, João V. Sá, Paulo Roque Lino et al. · Pharmaceutical Research Dec 2022 55
14 Design of experiments as a tool for LC–MS/MS method development for the trace analysis of the potentially genotoxic 4-dimethylaminopyridine impurity in glucocorticoids György Székely, Bruno Alexandre Pacheco de Castro Henriques, M. Gil et al. · Journal of Pharmaceutical and Biomedical Analysis 14 Jul 2012 55
15 Removal of potentially genotoxic acetamide and arylsulfonate impurities from crude drugs by molecular imprinting György Székely, Emelie Fritz, João Bandarra et al. · Journal of Chromatography A 5 Apr 2012 51
16 Pharmaceutical quality control laboratory digital twin – A novel governance model for resource planning and scheduling Miguel R. Lopes, Andrea Costigliola, Rui M. A. Pinto et al. · International Journal of Production Research 7 Nov 2019 48
17 Phospholipid imprinted polymers as selective endotoxin scavengers Robert Šulc, György Székely, Sudhirkumar Shinde et al. · Scientific Reports Open access 17 Mar 2017 47
18 Screening Methodologies for the Development of Spray-Dried Amorphous Solid Dispersions Íris Duarte, José Luís Santos, João F. Pinto et al. · Pharmaceutical Research 18 Aug 2014 45
19 Insights into the Release Mechanisms of ITZ:HPMCAS Amorphous Solid Dispersions: The Role of Drug-Rich Colloids Patrícia D. Nunes, João F. Pinto, João G. Henriques et al. · Molecular Pharmaceutics 17 Dec 2021 44
20 Design, preparation and characterization of novel molecularly imprinted polymers for removal of potentially genotoxic 1,3-diisopropylurea from API solutions György Székely, João Bandarra, William Heggie et al. · Separation and Purification Technology 13 Nov 2011 44
21 Bioactivity, mechanical properties and drug delivery ability of bioactive glass-ceramic scaffolds coated with a natural-derived polymer Marco Araújo, Raquel Viveiros, Anahí Philippart et al. · Materials Science and Engineering C 22 Mar 2017 40
22 Analytical Method Lifecycle Management in Pharmaceutical Industry: a Review Lúcia Volta e Sousa, Ricardo Jardim‐Gonçalves, José Cardoso de Menezes et al. · AAPS PharmSciTech Apr 2021 39
23 Role of Structure and Composition on the Performances of P-Type Tin Oxide Thin-Film Transistors Processed at Low-Temperatures Raquel Barros, Kachirayil Joseph Saji, Joao Carlos Waerenborgh et al. · Nanomaterials Open access Mar 2019 37
24 Optimization of supercritical CO2-assisted spray drying technology for the production of inhalable composite particles using quality-by-design principles Cláudia Moura, Teresa Casimiro, Eunice Costa et al. · Powder Technology 5 Sep 2019 36
25 Experimental design for the optimization and robustness testing of a liquid chromatography tandem mass spectrometry method for the trace analysis of the potentially genotoxic 1,3‐diisopropylurea György Székely, Bruno Alexandre Pacheco de Castro Henriques, Marco Gil et al. · Drug Testing and Analysis 15 Nov 2013 33
26 Green production of cocrystals using a new solvent-free approach by spray congealing Íris Duarte, Rita Andrade, João F. Pinto et al. · International Journal of Pharmaceutics 10 Apr 2016 32
27 Green approach on the development of lock-and-key polymers for API purification Raquel Viveiros, Maria Inês Lopes, William Heggie et al. · Chemical Engineering Journal 12 Sep 2016 31
28 Semi-continuous and continuous processes for enantiomeric separation Marina Ciriani, Rudi Oliveira, Carlos A. M. Afonso · Green Chemistry Open access 2022 29
29 Integration of industrial IoT architectures for dynamic scheduling Tiago Coito, Bernardo Firme, Miguel S. E. Martins et al. · Computers & Industrial Engineering Open access 30 Jun 2022 29
30 Rheological characterization of polymeric solutions used in spray drying process Tiago Porfirio, Francisco José Galindo-Rosales, Laura Campo-Deaño et al. · European Journal of Pharmaceutical Sciences Dec 2020 28
31 Comparison of traditional and mechanochemical production processes for nine active pharmaceutical ingredients (APIs) Emília P. T. Leitão · RSC Sustainability Open access 2024 26
32 In vitro dissolution/permeation tools for amorphous solid dispersions bioavailability forecasting II: Comparison and mechanistic insights Patrícia D. Nunes, Ana Ferreira, João F. Pinto et al. · European Journal of Pharmaceutical Sciences Open access 7 Jul 2023 26
33 Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations Georgia Kasten, Íris Duarte, Maria C. Paisana et al. · Pharmaceutics Open access 9 Jan 2019 26
34 Design of experiments approach on the preparation of dry inhaler chitosan composite formulations by supercritical CO2-assisted spray-drying Renato P. Cabral, Ana M. L. Sousa, Ana Sofia Silva et al. · The Journal of Supercritical Fluids 30 Apr 2016 26
35 Amorphous nasal powder advanced performance: in vitro/ex vivo studies and correlation with in vivo pharmacokinetics Patrícia Henriques, Joana Bicker, Andreia Carona et al. · Journal of Pharmaceutical Investigation Open access Sep 2023 25
36 Formulation of spray dried enzymes for dry powder inhalers: An integrated methodology Diana A. Fernandes, Eunice Costa, Paula Leandro et al. · International Journal of Pharmaceutics Open access 19 Jan 2022 24
37 Molecularly imprinted polymer strategies for removal of a genotoxic impurity, 4-dimethylaminopyridine, from an active pharmaceutical ingredient post-reaction stream Teresa Esteves, Raquel Viveiros, João Bandarra et al. · Separation and Purification Technology 25 Feb 2016 24
38 Chalcones: Retrospective Synthetic Approaches and Mechanistic Aspects of a Privileged Scaffold Emília P. T. Leitão · Current Pharmaceutical Design 3 Apr 2020 23
39 Antigenic response to CT ‐P13 and infliximab originator in inflammatory bowel disease patients shows similar epitope recognition João Victor Vieira Gonçalves et al. · Alimentary Pharmacology & Therapeutics Open access 5 Jun 2018 23
40 Production of nano-solid dispersions using a novel solvent-controlled precipitation process — Benchmarking their in vivo performance with an amorphous micro-sized solid dispersion produced by spray drying Íris Duarte, Maria Luísa Corvo, Pedro Serôdio et al. · European Journal of Pharmaceutical Sciences 10 Aug 2016 23
41 Statistical methodology for scale-up of an anti-solvent crystallization process in the pharmaceutical industry Ameessa Tulcidas, Susana Nascimento, B.A.V. Santos et al. · Separation and Purification Technology 11 Dec 2018 22
42 Spray Drying: Scale-Up and Manufacturing Filipe Gaspar, João Vicente, Filipe Carlos Figueiredo Pereira Neves et al. · Advances in delivery science and technology Book chapter 2014 22
43 Comprehensive powder flow characterization with reduced testing Catarina Chendo, João F. Pinto, Maria C. Paisana · International Journal of Pharmaceutics 4 Jun 2023 21
44 Augmenting Adaptive Machine Learning with Kinetic Modeling for Reaction Optimization A. Filipa Almeida, Filipe Ataíde, Rui M. S. Loureiro et al. · The Journal of Organic Chemistry 8 Jul 2021 21
45 Green Development of Polymeric Dummy Artificial Receptors with Affinity for Amide-Based Pharmaceutical Impurities Raquel Viveiros, Vasco D. B. Bonifácio, William Heggie et al. · ACS Sustainable Chemistry & Engineering 8 Aug 2019 20
46 Impact of jet-milling and wet-polishing size reduction technologies on inhalation API particle properties Cláudia Moura, Filipe Carlos Figueiredo Pereira Neves, Eunice Costa · Powder Technology 9 May 2016 20
47 Minimizing total completion time in large-sized pharmaceutical quality control scheduling Miguel S. E. Martins, Joaquim L. Viegas, Tiago Coito et al. · Journal of Heuristics Open access Feb 2023 18
48 Solution Methodology for Scheduling Problems in Batch Plants Samuel Moniz, Ana Paula Barbosa‐Póvoa, Jorge Pinho de Sousa et al. · Industrial & Engineering Chemistry Research Open access 13 Nov 2014 18
49 Many-objective optimization of a three-echelon supply chain: A case study in the pharmaceutical industry João Santos, João M. C. Sousa, Susana Margarida Vieira et al. · Computers & Industrial Engineering Open access 6 Oct 2022 17
50 Process Development of a Sonogashira Cross-Coupling Reaction as the Key Step of Tirasemtiv Synthesis Using Design of Experiments Ana C. F. Cruz, Elisabete M. Mateus, Matthew J. Peterson · Organic Process Research & Development 9 Mar 2021 17

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.