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Most cited papers from Institute of Aging

What are the most cited papers from Institute of Aging?

The most cited paper from Institute of Aging is "The global prevalence of dementia: A systematic review and metaanalysis" (Martin James Prince, Renata Bryce, Emiliano Albanese et al., 2013), with 4,986 citations. Next come "Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging" (2,192) and "Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia" (1,983).

Showing 50 of 60 papers. Every paper with more than 227 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The global prevalence of dementia: A systematic review and metaanalysis Martin James Prince, Renata Bryce, Emiliano Albanese et al. · Alzheimer s & Dementia ReviewOpen access 2013 4,986
2 Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging Gregory C. Kujoth, Asimina Hiona, Thomas D. Pugh et al. · Science 14 Jul 2005 2,192
3 Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia Fulvio Lauretani, Cosimo Roberto Russo, Stefania Bandinelli et al. · Journal of Applied Physiology Nov 2003 1,983
4 mTOR is a key modulator of ageing and age-related disease Simon C. Johnson, Peter S. Rabinovitch, Matt R. Kaeberlein · Nature Open access 15 Jan 2013 1,729
5 Executive summary of the Stages of Reproductive Aging Workshop + 10 Sioḃán D. Harlow, Margery L S Gass, Janet Elizabeth Hall et al. · Menopause The Journal of The North American Menopause Society Open access 13 Mar 2012 1,712
6 How Useful Is Body Mass Index for Comparison of Body Fatness across Age, Sex, and Ethnic Groups? Dympna Gallagher, Marjolein Visser, Diana E. Sepúlveda et al. · American Journal of Epidemiology Feb 1996 1,523
7 Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms Gijsbertus T. J. van der Horst, Manja Muijtjens, Kumiko Kobayashi et al. · Nature Apr 1999 1,432
8 The Geographic Distribution of Big Five Personality Traits David P. Schmitt, Jüri Allïk, Robert R. McCrae et al. · Journal of Cross-Cultural Psychology Open access 14 Feb 2007 1,226
9 Population based study of social and productive activities as predictors of survival among elderly Americans Thomas A. Glass, Carlos F. Mendes de Leon, Richard A. Marottoli et al. · BMJ Open access 21 Aug 1999 933
10 The Salience Network: A Neural System for Perceiving and Responding to Homeostatic Demands William W. Seeley · Journal of Neuroscience Open access Nov 2019 900
11 Sarcopenia != Dynapenia Brian C. Clark, Todd Matthew Manini · The Journals of Gerontology Series A Aug 2008 828
12 Executive summary of the Stages of Reproductive Aging Workshop +10: addressing the unfinished agenda of staging reproductive aging Sioḃán D. Harlow, Margery L S Gass, Janet Elizabeth Hall et al. · Climacteric Open access 16 Feb 2012 821
13 Measuring biological aging in humans: A quest Luigi Ferrucci, Marta González‐Freire, Elisa Fabbri et al. · Aging Cell Open access 12 Dec 2019 805
14 Age-related changes in cortical blood flow activation during visual processing of faces and location Cl Grady, JM Maisog, Barry Horwitz et al. · Journal of Neuroscience Open access Mar 1994 730
15 Role of cytosolic phospholipase A2 in allergic response and parturition Naonori Uozumi, Kazuhiko Kume, Takahide Nagase et al. · Nature Dec 1997 705
16 Rapid Colorectal Adenoma Formation Initiated by Conditional Targeting of the Apc Gene Hiroyuki Shibata, Kaoru Toyama, Hisashi Shioya et al. · Science 3 Oct 1997 622
17 PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene. E. Ogawa, Masato Maruyama, Hiroshi Kagoshima et al. · Proceedings of the National Academy of Sciences Open access 15 Jul 1993 620
18 The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer. Magali Olivier, Anita Langer√∏d, Patrizia Carrieri et al. · Clinical Cancer Research 15 Feb 2006 604
19 Preventing Falls Among Community-Dwelling Older Persons: Results From a Randomized Trial Mark C. Hornbrook, Victor J. Stevens, Darlene J. Wingfield et al. · The Gerontologist Feb 1994 562
20 Sister-chromatid exchanges: A report of the GENE-TOX program Samuel A. Latt, James W. Allen, Stephen E. Bloom et al. · Mutation Research/Reviews in Genetic Toxicology Jul 1981 559
21 Cutting Edge: The Common γ-Chain Is an Indispensable Subunit of the IL-21 Receptor Complex Hironobu Asao, Chikara Okuyama, Satoru Kumaki et al. · The Journal of Immunology Jul 2001 542
22 Training of Working Memory Impacts Structural Connectivity Hikaru Takeuchi, Atsushi Sekiguchi, Yasuyuki Taki et al. · Journal of Neuroscience Open access 3 Mar 2010 539
23 Predicting Changes in Physical Performance in a High-Functioning Elderly Cohort: MacArthur Studies of Successful Aging Teresa E. Seeman, Peter A. Charpentier, Lisa F. Berkman et al. · Journal of Gerontology May 1994 530
24 Analyses of repeated failures in cancer therapy for solid tumors: poor tumor‐selective drug delivery, low therapeutic efficacy and unsustainable costs Hiroshi Maeda, Mahin Khatami · Clinical and Translational Medicine Open access Mar 2018 496
25 The Sunnybrook Stroke Study Nathan Herrmann, Sandra E. Black, J. Lawrence et al. · Stroke Mar 1998 457
26 Do Muscle Mass, Muscle Density, Strength, and Physical Function Similarly Influence Risk of Hospitalization in Older Adults? Peggy Mannen Cawthon, Kathleen M. Fox, Shravanthi R. Gandra et al. · Journal of the American Geriatrics Society Open access 29 Jul 2009 419
27 IL-17 Enhances the Net Angiogenic Activity and In Vivo Growth of Human Non-Small Cell Lung Cancer in SCID Mice through Promoting CXCR-2-Dependent Angiogenesis Muneo Numasaki, Mika Watanabe, Takashi Suzuki et al. · The Journal of Immunology Open access Nov 2005 417
28 Roles and mechanisms of exosomal non-coding RNAs in human health and diseases Chen Li, Yu‐Qing Ni, Hui Xu et al. · Signal Transduction and Targeted Therapy Open access 10 Nov 2021 412
29 Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression Stephan Gehrke, Yuzuru Imai, Nicholas S. Sokol et al. · Nature Open access Jul 2010 404
30 Research priorities to reduce the global burden of dementia by 2025 Hiral Shah, Emiliano Albanese, Cynthia D. Duggan et al. · The Lancet Neurology Open access 11 Oct 2016 402
31 Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise Stephanie Eva Wohlgemuth, Arnold Young Seo, Emanuele Marzetti et al. · Experimental Gerontology Open access 12 Nov 2009 393
32 The Tohoku Medical Megabank Project: Design and Mission Shinichi Kuriyama et al. · Journal of Epidemiology Open access 2016 388
33 Acute Stress Affects Heart Rate Variability During Sleep Martica H. Hall, Raymond Vasko, Daniel J. Buysse et al. · Psychosomatic Medicine 2004 378
34 Skeletal muscle apoptosis, sarcopenia and frailty at old age Emanuele Marzetti, Christiaan Leeuwenburgh · Experimental Gerontology 19 Oct 2006 351
35 Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice Tomonori Kaifu, Jin Nakahara, Masanori Inui et al. · Journal of Clinical Investigation Open access Feb 2003 349
36 Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass Index Andrew P. Feinberg, Rafael A. Irizarry, Delphine Fradin et al. · Science Translational Medicine Open access 15 Sep 2010 341
37 18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease Ryuichi Harada et al. · Journal of Nuclear Medicine Open access 5 Nov 2015 333
38 ESGO–ESMO–ESP consensus conference recommendations on ovarian cancer: pathology and molecular biology and early, advanced and recurrent disease Jonathan A. Ledermann et al. · Annals of Oncology Open access Feb 2024 327
39 Developmental Trajectories in Children With and Without Autism Spectrum Disorders: The First 3 Years Rebecca J. Landa, Alden L. Gross, Elizabeth A. Stuart et al. · Child Development Open access 30 Oct 2012 323
40 Differential Role of TLR- and RLR-Signaling in the Immune Responses to Influenza A Virus Infection and Vaccination Shohei Koyama, Ken J. Ishii, Himanshu Kumar et al. · The Journal of Immunology Oct 2007 311
41 Correlates of Daytime Sleepiness in 4578 Elderly Persons: The Cardiovascular Health Study Coralyn W. Whitney, Paul Enright, Anne B. Newman et al. · SLEEP Open access 1998 302
42 Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms Marito Araki, Yinjie Yang, Nami Masubuchi et al. · Blood Open access 27 Jan 2016 301
43 Biomarkers of sarcopenia in clinical trials—recommendations from the International Working Group on Sarcopenia Matteo Cesari et al. · Journal of Cachexia Sarcopenia and Muscle Open access 2 Aug 2012 293
44 Novel 18F-Labeled Arylquinoline Derivatives for Noninvasive Imaging of Tau Pathology in Alzheimer Disease Nobuyuki Okamura, Shozo Furumoto, Ryuichi Harada et al. · Journal of Nuclear Medicine Open access 15 Jul 2013 290
45 Vasohibin as an endothelium-derived negative feedback regulator of angiogenesis Kazuhide Watanabe, Yasuhiro Hasegawa, Hiroshi Yamashita et al. · Journal of Clinical Investigation Open access Oct 2004 289
46 Infiltration of COX-2–expressing macrophages is a prerequisite for IL-1β–induced neovascularization and tumor growth Shintaro Nakao, Takashi Kuwano, Chikako Tsutsumi‐Miyahara et al. · Journal of Clinical Investigation Open access 26 Oct 2005 287
47 NRF2 addiction in cancer cells Hiroshi Kitamura, Hozumi Motohashi · Cancer Science Open access 16 Feb 2018 282
48 Pilot Study of Resveratrol in Older Adults With Impaired Glucose Tolerance Jill P. Crandall, Valerie Oram, Georgeta G. Trandafirescu et al. · The Journals of Gerontology Series A Open access 4 Jan 2012 280
49 Circulating Transforming Growth Factor-β in Marfan Syndrome Peter Matt, Florian Schoenhoff, Jennifer Pardo Habashi et al. · Circulation Open access 28 Jul 2009 274
50 Regional White Matter Hyperintensity Volume, Not Hippocampal Atrophy, Predicts Incident Alzheimer Disease in the Community Adam M. Brickman, Frank A. Provenzano, Jordan Muraskin et al. · Archives of Neurology Open access 28 Aug 2012 260

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.