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Most cited papers from Integrated Laboratory Systems, Inc.

What are the most cited papers from Integrated Laboratory Systems, Inc.?

The most cited paper from Integrated Laboratory Systems, Inc. is "Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing" (Raymond R. Tice, Eva Agurell, Diana Anderson et al., 2000), with 4,883 citations. Next come "Normal Structure, Function, and Histology of the Spleen" (885) and "IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans" (792).

Showing 50 of 60 papers. Every paper with more than 108 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing Raymond R. Tice, Eva Agurell, Diana Anderson et al. · Environmental and Molecular Mutagenesis 6 Jun 2000 4,883
2 Normal Structure, Function, and Histology of the Spleen Mark F. Cesta · Toxicologic Pathology Aug 2006 885
3 IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans Richard J. Albertini, Diana Anderson, George R. Douglas et al. · Mutation Research/Reviews in Mutation Research Aug 2000 792
4 Biomarkers of Oxidative Stress Study II: Are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Maria B. Kadiiska et al. · Free Radical Biology and Medicine 15 Dec 2004 699
5 Health consequences of electric lighting practices in the modern world: A report on the National Toxicology Program's workshop on shift work at night, artificial light at night, and circadian disruption Ruth M. Lunn et al. · The Science of The Total Environment Open access 27 Jul 2017 412
6 Normal Structure, Function, and Histology of Mucosa-Associated Lymphoid Tissue Mark F. Cesta · Toxicologic Pathology Open access Aug 2006 389
7 CERAPP: Collaborative Estrogen Receptor Activity Prediction Project Kamel Mansouri et al. · Environmental Health Perspectives Open access 23 Feb 2016 377
8 Growth of uterine leiomyomata among premenopausal black and white women Shyamal D. Peddada, Shannon K. Laughlin, Kelly Miner et al. · Proceedings of the National Academy of Sciences Open access Dec 2008 365
9 The Orphan Nuclear Receptor Constitutive Active/Androstane Receptor Is Essential for Liver Tumor Promotion by Phenobarbital in Mice Yukio Yamamoto, Rick Moore, Thomas L. Goldsworthy et al. · Cancer Research 15 Oct 2004 348
10 In vivo rodent erythrocyte micronucleus assay Makoto Hayashi, Raymond R. Tice, James T. MacGregor et al. · Mutation Research/Environmental Mutagenesis and Related Subjects Jun 1994 342
11 Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead William H. Goodson et al. · Carcinogenesis Open access173 authors Jun 2015 324
12 The Salmonella typhimurium/mammalian microsomal assay Larry Kier, David Brusick, Angela E. Auletta et al. · Mutation Research/Reviews in Genetic Toxicology Sep 1986 290
13 Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model Patience Browne, Richard Judson, Warren Casey et al. · Environmental Science & Technology 12 Jun 2015 279
14 Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes Linda M. Sargent, Dale W. Porter, Lauren M. Staska et al. · Particle and Fibre Toxicology Open access 2014 259
15 In silico toxicology protocols Glenn J. Myatt et al. · Regulatory Toxicology and Pharmacology Open access 17 Apr 2018 245
16 A microgel electrophoresis technique for the direct quantitation of DNA damage and repair in individual fibroblasts cultured on microscope slides Narendra Prasad Singh, Raymond R. Tice, Ralph E. Stephens et al. · Mutation Research/Environmental Mutagenesis and Related Subjects Jun 1991 245
17 In vitro to in vivo extrapolation for high throughput prioritization and decision making Shannon M. Bell et al. · Toxicology in Vitro Open access 5 Dec 2017 244
18 Development and Validation of a Computational Model for Androgen Receptor Activity Nicole Kleinstreuer, Patricia C. Ceger, Eric D. Watt et al. · Chemical Research in Toxicology Open access 19 Nov 2016 220
19 CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity Kamel Mansouri et al. · Environmental Health Perspectives Open access Feb 2020 218
20 A Central Limit Theorem for Latin Hypercube Sampling Art B. Owen · Journal of the Royal Statistical Society Series B (Statistical Methodology) 1992 218
21 DNA damage and rpair with age in individual human lymphocytes Narendra Prasad Singh, David B. Danner, Raymond R. Tice et al. · Mutation Research/DNAging May 1990 217
22 Genotoxicity of radiofrequency signals. I. Investigation of DNA damage and micronuclei induction in cultured human blood cells Raymond R. Tice, Graham G. Hook, Maria E. Donner et al. · Bioelectromagnetics 23 Jan 2002 216
23 STopTox: An in Silico Alternative to Animal Testing for Acute Systemic and Topical Toxicity Joyce Villa Verde Bastos Borba, Vinícius M. Alves, Rodolpho C. Braga et al. · Environmental Health Perspectives Open access Feb 2022 208
24 In Silico Prediction of Physicochemical Properties of Environmental Chemicals Using Molecular Fingerprints and Machine Learning Qingda Zang, Kamel Mansouri, Antony John Williams et al. · Journal of Chemical Information and Modeling Open access 25 Dec 2016 208
25 Non-animal methods to predict skin sensitization (II): an assessment of defined approaches Nicole Kleinstreuer et al. · Critical Reviews in Toxicology Open access 23 Feb 2018 206
26 SAR and QSAR modeling of a large collection of LD50 rat acute oral toxicity data Domenico Gadaleta, Kristijan Vuković, Cosimo Toma et al. · Journal of Cheminformatics Open access 30 Aug 2019 205
27 Gene Expression Profiling of Rat Livers Reveals Indicators of Potential Adverse Effects Alexandra N. Heinloth, Richard D. Irwin, Gary A. Boorman et al. · Toxicological Sciences 14 Apr 2004 205
28 The Single Cell Gel (SCG) Assay: An Electrophoretic Technique for the Detection of DNA Damage in Individual Cells Raymond R. Tice, Peter W. Andrews, Osamu HIRAI et al. · Advances in experimental medicine and biology Book chapter 1991 204
29 KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling Klaus W. Wagner, Hunain Alam, Shilpa S. Dhar et al. · Journal of Clinical Investigation Open access 7 Nov 2013 199
30 Open-source QSAR models for pKa prediction using multiple machine learning approaches Kamel Mansouri, Neal F. Cariello, Alexandru V. Korotcov et al. · Journal of Cheminformatics Open access 18 Sep 2019 192
31 Sister-chromatid exchange: second report of the Gene-Tox program James D. Tucker, Angela E. Auletta, Michael C. Cimino et al. · Mutation Research/Reviews in Genetic Toxicology Sep 1993 182
32 Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway Ruili Huang et al. · Scientific Reports Open access 11 Jul 2014 171
33 EPA’s non-targeted analysis collaborative trial (ENTACT): genesis, design, and initial findings Elin M. Ulrich, Jon R. Sobus, Chris Grulke et al. · Analytical and Bioanalytical Chemistry Open access 5 Dec 2018 167
34 On the performance of membraneless laminar flow-based fuel cells Ranga S. Jayashree, Seong Kee Yoon, Fikile Richard Brushett et al. · Journal of Power Sources 17 Dec 2009 166
35 The single cell gel electrophoresis/comet assay: a potential tool for detecting radiation-induced DNA damage in humans. Raymond R. Tice, Gary H. Strauss · PubMed May 1995 165
36 Evaluation of the Association between Maternal Smoking, Childhood Obesity, and Metabolic Disorders: A National Toxicology Program Workshop Review Mamta Behl, Deepa P. Rao, Kjersti Marie Aagaard et al. · Environmental Health Perspectives Open access 11 Dec 2012 162
37 The Single Cell Gel Assay: A Sensitive Technique for Evaluating Intercellular Differences in DNA Damage and Repair Raymond R. Tice, Paul W. Andrews, Narendra Prasad Singh Book chapter 1990 160
38 Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water Ivy D. Moffat, Nikolai Leonidovitch Chepelev, Sarah Labib et al. · Critical Reviews in Toxicology Open access 2 Jan 2015 156
39 Role of Estrogen Receptor Signaling Required for Endometriosis-Like Lesion Establishment in a Mouse Model Katherine A. Burns, Karina F. Rodriguez, Sylvia C. Hewitt et al. · Endocrinology Open access 14 Jun 2012 152
40 CATMoS: Collaborative Acute Toxicity Modeling Suite Kamel Mansouri et al. · Environmental Health Perspectives Open access102 authors Apr 2021 149
41 CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice Carol S. Trempus, Rebecca Morris, Matthew Ehinger et al. · Cancer Research Open access May 2007 143
42 Empirical Bayes Procedures for Stabilizing Maps of U.S. Cancer Mortality Rates Kenneth G. Mantón, Max A. Woodbury, Eric Stallard et al. · Journal of the American Statistical Association Sep 1989 141
43 Proliferative and Nonproliferative Lesions of the Rat and Mouse Central and Peripheral Nervous Systems Wolfgang S.H. Kaufmann, Brad N. Bolon, Alys Bradley et al. · Toxicologic Pathology 25 May 2012 138
44 Characterizing and predicting carcinogenicity and mode of action using conventional and toxicogenomics methods Michael D. Waters, Marcus A Jackson, Isabel A. Lea · Mutation Research/Reviews in Mutation Research 26 Apr 2010 134
45 Fetal Mouse Phthalate Exposure Shows that Gonocyte Multinucleation is Not Associated with Decreased Testicular Testosterone Kevin W. Gaido, Janan B. Hensley, Delong Liu et al. · Toxicological Sciences Open access 14 Mar 2007 131
46 Assessment of radiation-induced DNA damage in human blood lymphocytes using the single-cell gel electrophoresis technique Vijayalaxmi, Raymond R. Tice, Gary H. Strauss · Mutation Research/Environmental Mutagenesis and Related Subjects Jun 1992 131
47 IRGM1 links mitochondrial quality control to autoimmunity Prashant Rai, Kyathanahalli S. Janardhan, Julie M. Meacham et al. · Nature Immunology Open access 28 Jan 2021 130
48 High-dose combination alkylating agents with autologous bone-marrow support in patients with breast cancer: preliminary assessment of DNA damage in individual peripheral blood lymphocytes using the single cell gel electrophoresis assay Raymond R. Tice, Gary H. Strauss, William P. Peters · Mutation Research/Environmental Mutagenesis and Related Subjects 1992 130
49 Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity John Edgar French, Daniel M. Gatti, Daniel L. Morgan et al. · Environmental Health Perspectives Open access 6 Nov 2014 128
50 Influence of ultraviolet light on the toxicity of sediments contaminated with polycyclic aromatic hydrocarbons Gerald T. Ankley, Scott A. Collyard, Philip D. Monson et al. · Environmental Toxicology and Chemistry Nov 1994 126

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.