Science Explorer Back to mapMap
Discussion
Institution · Io Therapeutics (United States)

Most cited papers from Io Therapeutics (United States)

Io Therapeutics (United States)

What are the most cited papers from Io Therapeutics (United States)?

The most cited paper from Io Therapeutics (United States) is "ISCEV Standard for full-field clinical electroretinography (2015 update)" (Daphne L. McCulloch, Michael F. Marmor, Mitchell Brigell et al., 2014), with 1,329 citations. Next come "Cloned pigs produced by nuclear transfer from adult somatic cells" (1,258) and "Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs" (714).

Showing 50 of 60 papers. Every paper with more than 83 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 ISCEV Standard for full-field clinical electroretinography (2015 update) Daphne L. McCulloch, Michael F. Marmor, Mitchell Brigell et al. · Documenta Ophthalmologica Open access 13 Dec 2014 1,329
2 Cloned pigs produced by nuclear transfer from adult somatic cells Irina A. Polejaeva, Shu-Hung Chen, Todd D. Vaught et al. · Nature Sep 2000 1,258
3 Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs Yifan Dai, Todd D. Vaught, Jeremy T. Boone et al. · Nature Biotechnology Mar 2002 714
4 Curcumin Suppresses the Paclitaxel-Induced Nuclear Factor-κB Pathway in Breast Cancer Cells and Inhibits Lung Metastasis of Human Breast Cancer in Nude Mice Bharat Bhushan Aggarwal, Shishir Shishodia, Yasunari Takada et al. · Clinical Cancer Research 15 Oct 2005 583
5 A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality Val Mann, Emma E. Hobson, Baohua Li et al. · Journal of Clinical Investigation Open access Apr 2001 471
6 Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2. Brian K. Reuter, Samuel Asfaha, André G. Buret et al. · Journal of Clinical Investigation Open access Nov 1996 425
7 An immune-based biomarker signature is associated with mortality in COVID-19 patients Michael S. Abers et al. · JCI Insight Open access 24 Nov 2020 370
8 Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists Kengo Shimono, Wei-en Tung, Christine Macolino et al. · Nature Medicine Open access Apr 2011 340
9 Amyloid β Protein Dimer-Containing Human CSF Disrupts Synaptic Plasticity: Prevention by Systemic Passive Immunization Igor V. Klyubin, Vicki Betts, Alfred T. Welzel et al. · Journal of Neuroscience Open access 16 Apr 2008 320
10 Functional Connectome of the Striatal Medium Spiny Neuron Nao Chuhma, Kenji F. Tanaka, René Hen et al. · Journal of Neuroscience Open access 26 Jan 2011 279
11 Molecular Characterization of Human 4Ig-B7-H3, a Member of the B7 Family with Four Ig-Like Domains Peter Steinberger, Otto Majdic, Sophia V. Derdak et al. · The Journal of Immunology Open access Feb 2004 278
12 Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial Mark M. Yarchoan, Edward John Gane, Thomas Urban Marron et al. · Nature Medicine Open access Apr 2024 249
13 BDNF Overexpression in the Forebrain Rescues Huntington's Disease Phenotypes in YAC128 Mice Yuxiang Xie, Michael R. Hayden, Baoji Xu · Journal of Neuroscience Open access 3 Nov 2010 240
14 Alzheimer's Disease Brain-Derived Amyloid-β-Mediated Inhibition of LTPIn VivoIs Prevented by Immunotargeting Cellular Prion Protein Andrew E. Barry, Igor V. Klyubin, Jessica M. Mc Donald et al. · Journal of Neuroscience Open access 18 May 2011 237
15 Glutamatergic Modulators: The Future of Treating Mood Disorders? Carlos A. Zarate, Rodrigo Machado‐Vieira, Ioline D. Henter et al. · Harvard Review of Psychiatry Open access Aug 2010 228
16 Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature Jikui Shen, Maike Frye, Bonnie L. Lee et al. · Journal of Clinical Investigation Open access Sep 2014 228
17 BCMA-CD19 compound CAR T cells for systemic lupus erythematosus: a phase 1 open-label clinical trial Weijia Wang et al. · Annals of the Rheumatic Diseases 22 May 2024 227
18 Ovarian Cancer-associated Mutations Disable Catalytic Activity of CDK12, a Kinase That Promotes Homologous Recombination Repair and Resistance to Cisplatin and Poly(ADP-ribose) Polymerase Inhibitors Poorval M. Joshi, Shari L. Sutor, Catherine J. Huntoon et al. · Journal of Biological Chemistry Open access 20 Feb 2014 207
19 Ca2+-dependent hydrophobic-interaction chromatography. Isolation of a novel Ca2+-binding protein and protein kinase C from bovine brain Michael P. Walsh, Karen A. Valentine, P K Ngai et al. · Biochemical Journal Open access 15 Nov 1984 202
20 Endoplasmic Reticulum Stress Activates Unfolded Protein Response Signaling and Mediates Inflammation, Obesity, and Cardiac Dysfunction: Therapeutic and Molecular Approach Omar Mohammed Amen, Satyajit Dey Sarker, Reena Ghildyal et al. · Frontiers in Pharmacology Open access 10 Sep 2019 195
21 HLA-independent T cell receptors for targeting tumors with low antigen density Jorge Mansilla‐Soto et al. · Nature Medicine Open access 13 Jan 2022 189
22 Excitotoxic Death of Retinal NeuronsIn VivoOccurs via a Non-Cell-Autonomous Mechanism Frédéric Lebrun-Julien, Laure Duplan, Vincent Pernet et al. · Journal of Neuroscience Open access 29 Apr 2009 186
23 The Effect of Keto-analogues of Essential Amino Acids in Severe Chronic Uremia Mackenzie Walser, A.W. Coulter, S.K. DIGHE et al. · Journal of Clinical Investigation Open access Mar 1973 179
24 Sudden Cardiac Death in the Young Michael John Ackerman, Dianne L. Atkins, John K. Triedman · Circulation Open access 7 Mar 2016 168
25 Augmentation of organ-associated natural killer activity by biological response modifiers. Isolation and characterization of large granular lymphocytes from the liver. Robert H. Wiltrout, Bonnie J. Mathieson, James E. Talmadge et al. · The Journal of Experimental Medicine Open access Nov 1984 166
26 Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel Ting‐Chao Chou, Xiu-Guo Zhang, Christina R. Harris et al. · Proceedings of the National Academy of Sciences Open access 22 Dec 1998 165
27 Host-response biomarkers for diagnosis of late-onset septicemia and necrotizing enterocolitis in preterm infants Pak Cheung Ng, Irene Ling Ang, Rossa Wai Kwun Chiu et al. · Journal of Clinical Investigation Open access 30 Jun 2010 162
28 The Impact of Efflux Transporters in the Brain on the Development of Drugs for CNS Disorders Eve M. Taylor · Clinical Pharmacokinetics 2002 153
29 A Novel Polyacrylamide Magnetic Nanoparticle Contrast Agent for Molecular Imaging using MRI Bradford Armstrong Moffat, G. Ramachandra Reddy, Patrick McConville et al. · Molecular Imaging Open access Oct 2003 152
30 Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors Lei Zhou, Kimberly M. Lovell, Kevin J. Frankowski et al. · Journal of Biological Chemistry Open access Nov 2013 150
31 High-fat diet-induced juvenile obesity leads to cardiomyocyte dysfunction and upregulation of Foxo3a transcription factor independent of lipotoxicity and apoptosis David P. Relling, Lucy B. Esberg, Cindy X. Fang et al. · Journal of Hypertension 8 Feb 2006 150
32 Metastatic patterns of choroidal melanoma Lawrence H. Einhorn, Michael A. Burgess, Jeffrey A. Gottlieb · Cancer Open access Oct 1974 147
33 Cell cycle–related kinase is a direct androgen receptor–regulated gene that drives β-catenin/T cell factor–dependent hepatocarcinogenesis Hai Feng, Alfred S.L. Cheng, Daisy P. Tsang et al. · Journal of Clinical Investigation Open access 11 Jul 2011 142
34 Relationship of Sleep Quantity and Quality with 24-Hour Urinary Catecholamines and Salivary Awakening Cortisol in Healthy Middle-Aged Adults Jihui Zhang, Ronald C.W., Alice PS Kong et al. · SLEEP Open access Feb 2011 137
35 An Open-Label Dose Escalation Study to Evaluate the Safety of Administration of Nonviral Stromal Cell-Derived Factor-1 Plasmid to Treat Symptomatic Ischemic Heart Failure Marc S. Penn, Farrell O. Mendelsohn, Gary L. Schaer et al. · Circulation Research 22 Feb 2013 135
36 Vitamin D Deficiency Promotes Skeletal Muscle Hypersensitivity and Sensory Hyperinnervation Sarah E. Tague, Gwenaëlle L. Clarke, Michelle K. Winter et al. · Journal of Neuroscience Open access 28 Sep 2011 129
37 Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1) Toufike Kanouni, Christophe Severin, Robert W. Cho et al. · Journal of Medicinal Chemistry Open access 9 Oct 2020 126
38 SDF-1 in myocardial repair Marc S. Penn, Joseph Pastore, Timothy J. Miller et al. · Gene Therapy Jun 2012 125
39 A four-year experience with anthracycline, cytosine arabinoside, vincristine and prednisone combination chemotherapy in 325 adults with acute leukemia Michael J. Keating, Terry L. Smith, K. B. McCredie et al. · Cancer Open access 15 Jun 1981 124
40 A retinoic acid–dependent checkpoint in the development of CD4+ T cell–mediated immunity Karina Pino‐Lagos, Yanxia Guo, Chrysothemis C. Brown et al. · The Journal of Experimental Medicine Open access 22 Aug 2011 123
41 Repression of GSK3 restores NK cell cytotoxicity in AML patients Reshmi Parameswaran, Parameswaran Ramakrishnan, Stephen A. Moreton et al. · Nature Communications Open access 4 Apr 2016 115
42 Optical visualisation of thermogenesis in stimulated single-cell brown adipocytes Rókus Kriszt et al. · Scientific Reports Open access 25 Apr 2017 112
43 Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapy-induced nausea and vomiting Montague Lane, Charles L. Vogel, Julie Ferguson et al. · Journal of Pain and Symptom Management Open access Aug 1991 112
44 RING domain–deficient BRCA1 promotes PARP inhibitor and platinum resistance Yifan Wang, John J. Krais, Andrea J. Bernhardy et al. · Journal of Clinical Investigation Open access 24 Jul 2016 110
45 Platelet activation is increased in peripheral arterial disease Kevin Cassar, Paul Bachoo, I Ford et al. · Journal of Vascular Surgery Open access 30 Jun 2003 110
46 RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex Nicholas Gene Brown, Ryan T. VanderLinden, Edmond R. Watson et al. · Proceedings of the National Academy of Sciences Open access 30 Mar 2015 108
47 PD-1 silencing impairs the anti-tumor function of chimeric antigen receptor modified T cells by inhibiting proliferation activity Jianshu Wei, Can Luo, Yao Wang et al. · Journal for ImmunoTherapy of Cancer Open access 7 Aug 2019 106
48 Plasmid-based transient human stromal cell-derived factor-1 gene transfer improves cardiac function in chronic heart failure Srividya Sundararaman, Timothy J. Miller, Joseph Pastore et al. · Gene Therapy Open access 7 Apr 2011 106
49 International classification of radiographs of pneumoconioses. P. C. Elmes · Occupational and Environmental Medicine Open access 1971 103
50 MLN4924 induces Noxa upregulation in acute myelogenous leukemia and synergizes with Bcl-2 inhibitors Katherine L. B. Knorr, Pascale Schneider, X. Wei Meng et al. · Cell Death and Differentiation Open access 5 Jun 2015 100

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.