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Company · Santa Ana · United States

Io Therapeutics (United States)

In research, Io Therapeutics (United States) stands highest in Molecular Biology (#1,758 of 1,880 worldwide), Biochemistry, Genetics and Molecular Biology (#2,818 of 2,964 worldwide) and Medicine (#8,357 of 8,541 worldwide), 2022-now. Relative to its size it is most specialised in Oncology, Immunology and Molecular Biology (Oncology is 12.3× its share of world research).

io-therapeutics.comROR OpenAlex
World rank, 2022-now
#22,219
of 22,385 · #24,690 all time
Rank in United States
#3,304
of 3,332
Research works
761
▲ 257% vs 2018-21
Citations
16k
21.6 per fractional work
Top-10% rate
11.7%
all institutions 10.0%
vs its own fields
0.84×
1.00× is exactly expected
Open access
44%
world 40%
International
30%
world 18%
Io Therapeutics (United States)

What is Io Therapeutics (United States) known for in research?

The fields where it stands highest, 2022-now, ranked among every institution above the floor in each field.

FieldWorld rankWhere that sitsTop-10% rateWorksAll time
Molecular BiologySubfield #1,758 of 1,880 8.1%75 #2692
Biochemistry, Genetics and Molecular BiologyField #2,818 of 2,964 8.4%106 #3743
MedicineField #8,357 of 8,541 13.6%145 #10033
Health SciencesDomain #9,708 of 9,902 13.5%148 #12057
Life SciencesDomain #6,319 of 6,403 10.6%143 #8009

Each strip is that field's whole ranked pool, with the notch where Io Therapeutics (United States) sits in it, in the colour of the band that rank falls in. The track under the rate is the rate itself: it carries no average mark, because the average differs by field (from about 6% in Dentistry to 21% in Economics).

Which of those standings moved

The same fields on both windows: where it stood over the whole record, and where it stands in 2022-now. The distance is the story, and it is the one thing the two rank columns above cannot show.

  1. Molecular Biology#2,692 #1,758
  2. Biochemistry, Genetics and Molecular Biology#3,743 #2,818
  3. Medicine#10,033 #8,357
  4. Health Sciences#12,057 #9,708
  5. Life Sciences#8,009 #6,319
all time2022-now, better2022-now, worse

A dot further right is a better standing. Fields it was not ranked in over the whole record are left out.

Which fields of science does Io Therapeutics (United States) work in?

In 2022-now, 47% of research at Io Therapeutics (United States) is in Health Sciences, 44% in Life Sciences. Its largest fields are Medicine (46%), Biochemistry, Genetics and Molecular Biology (32%), Immunology and Microbiology (8%). It does 3.2× the world's share of Life Sciences.

Health Sciences: 192 fractional works · 46.9% of its workMedicine: 188 fractional works · 46.0% of its workOncology: 57 fractional works · 13.8% of its workPulmonary and Respiratory Medicine: 25 fractional works · 6.0% of its workRadiology, Nuclear Medicine and Imaging: 19 fractional works · 4.6% of its workHematology: 8 fractional works · 2.0% of its workPhysiology: 8 fractional works · 1.8% of its workSurgery: 7 fractional works · 1.8% of its workEpidemiology: 7 fractional works · 1.7% of its workPathology and Forensic Medicine: 5 fractional works · 1.3% of its workGenetics: 5 fractional works · 1.3% of its workNeurology: 5 fractional works · 1.3% of its workCardiology and Cardiovascular Medicine: 5 fractional works · 1.1% of its workPharmacology: 4 fractional works · 1.0% of its workPublic Health, Environmental and Occupational Health: 4 fractional works · 1.0% of its workEndocrinology, Diabetes and Metabolism: 3 fractional works · 0.8% of its workInfectious Diseases: 3 fractional works · 0.7% of its workDermatology: 3 fractional works · 0.7% of its workRheumatology: 3 fractional works · 0.7% of its workPsychiatry and Mental health: 3 fractional works · 0.6% of its workImmunology and Allergy: 2 fractional works · 0.5% of its workPediatrics, Perinatology and Child Health: 2 fractional works · 0.5% of its workHepatology: 1 fractional works · 0.3% of its workNephrology: 1 fractional works · 0.3% of its workTransplantation: 1 fractional works · 0.3% of its workRehabilitation: 1 fractional works · 0.2% of its workReproductive Medicine: 1 fractional works · 0.2% of its workSmaller subfields together: 5 fractional works · 1.3% of its workHealth Professions: 2 fractional works · 0.4% of its workGeneral Health Professions: 1 fractional works · 0.2% of its workSmaller subfields together: 1 fractional works · 0.2% of its workNursing: 1 fractional works · 0.3% of its workNutrition and Dietetics: 1 fractional works · 0.3% of its workVeterinary: 1 fractional works · 0.2% of its workDentistry: 0 fractional works · 0.1% of its workLife Sciences: 181 fractional works · 44.3% of its workBiochemistry, Genetics and Molecular Biology: 131 fractional works · 32.1% of its workMolecular Biology: 95 fractional works · 23.2% of its workCancer Research: 12 fractional works · 3.0% of its workGenetics: 10 fractional works · 2.4% of its workBiotechnology: 5 fractional works · 1.2% of its workCell Biology: 4 fractional works · 0.9% of its workBiochemistry: 2 fractional works · 0.5% of its workBiophysics: 1 fractional works · 0.3% of its workSmaller subfields together: 3 fractional works · 0.7% of its workImmunology and Microbiology: 31 fractional works · 7.6% of its workImmunology: 30 fractional works · 7.4% of its workSmaller subfields together: 1 fractional works · 0.2% of its workNeuroscience: 11 fractional works · 2.7% of its workCellular and Molecular Neuroscience: 5 fractional works · 1.1% of its workNeurology: 3 fractional works · 0.8% of its workCognitive Neuroscience: 3 fractional works · 0.6% of its workSmaller subfields together: 1 fractional works · 0.2% of its workPharmacology, Toxicology and Pharmaceutics: 6 fractional works · 1.4% of its workPharmaceutical Science: 3 fractional works · 0.8% of its workToxicology: 1 fractional works · 0.3% of its workPharmacology: 1 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.0% of its workAgricultural and Biological Sciences: 2 fractional works · 0.5% of its workPhysical Sciences: 26 fractional works · 6.3% of its workEngineering: 7 fractional works · 1.6% of its workBiomedical Engineering: 6 fractional works · 1.5% of its workSmaller subfields together: 1 fractional works · 0.2% of its workChemistry: 6 fractional works · 1.4% of its workOrganic Chemistry: 4 fractional works · 0.9% of its workSpectroscopy: 1 fractional works · 0.3% of its workSmaller subfields together: 1 fractional works · 0.2% of its workMaterials Science: 5 fractional works · 1.3% of its workBiomaterials: 3 fractional works · 0.7% of its workMaterials Chemistry: 2 fractional works · 0.5% of its workSmaller subfields together: 1 fractional works · 0.1% of its workComputer Science: 3 fractional works · 0.9% of its workComputational Theory and Mathematics: 2 fractional works · 0.6% of its workArtificial Intelligence: 1 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.0% of its workEnvironmental Science: 2 fractional works · 0.5% of its workEcology: 1 fractional works · 0.3% of its workSmaller subfields together: 1 fractional works · 0.2% of its workMathematics: 1 fractional works · 0.4% of its workStatistics and Probability: 1 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.0% of its workPhysics and Astronomy: 1 fractional works · 0.2% of its workChemical Engineering: 0 fractional works · 0.0% of its workSocial Sciences: 10 fractional works · 2.4% of its workPsychology: 4 fractional works · 1.1% of its workClinical Psychology: 3 fractional works · 0.6% of its workSmaller subfields together: 2 fractional works · 0.4% of its workEconomics, Econometrics and Finance: 3 fractional works · 0.8% of its workEconomics and Econometrics: 3 fractional works · 0.8% of its workSocial Sciences: 2 fractional works · 0.4% of its workDecision Sciences: 1 fractional works · 0.1% of its workArts and Humanities: 0 fractional works · 0.1% of its workALL ITS WORKIo Therapeutics(United States)409fractional works, 2022-now
Life Sciences44%Physical Sciences6%Health Sciences47%Social Sciences2%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in 2022-now. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 25 fields, with their numbers
    1. Medicine18846.0%
    2. Health Professions20.4%
    3. Nursing10.3%
    4. Veterinary10.2%
    5. Dentistry00.1%
    1. Biochemistry, Genetics and Molecular Biology13132.1%
    2. Immunology and Microbiology317.6%
    3. Neuroscience112.7%
    4. Pharmacology, Toxicology and Pharmaceutics61.4%
    5. Agricultural and Biological Sciences20.5%
    1. Engineering71.6%
    2. Chemistry61.4%
    3. Materials Science51.3%
    4. Computer Science30.9%
    5. Environmental Science20.5%
    6. Mathematics10.4%
    7. Physics and Astronomy10.2%
    8. Chemical Engineering00.0%
    9. Energy00.0%
    1. Psychology41.1%
    2. Economics, Econometrics and Finance30.8%
    3. Social Sciences20.4%
    4. Decision Sciences10.1%
    5. Arts and Humanities00.1%
    6. Business, Management and Accounting00.0%
All of science, and how each field's share has moved since 1950: the Science domain explorer

What does Io Therapeutics (United States) specialise in?

Where its research is concentrated relative to its size: Oncology takes 12.3× the share of its output that it takes of world research.

  1. OncologySubfield · 56.5 works12×
  2. ImmunologySubfield · 30.2 works11×
  3. Molecular BiologySubfield · 94.7 works7.7×
  4. Immunology and MicrobiologyField · 30.9 works7.5×
← less than its size predicts1×more →

Location quotient, a volume reading rather than an impact one. It surfaces small, lopsided specialities.

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 0.10× its world share, 2 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 6.03× its world share, 131 worksBiochemistry, Geneti…Immunology and Microbiology: 7.51× its world share, 31 worksImmunology and Micro…Neuroscience: 1.69× its world share, 11 worksNeurosciencePharmacology, Toxicology and Pharmaceutics: 3.98× its world share, 6 worksPharmacology, Toxico…Chemical Engineering: 0.12× its world share, 0 worksChemical EngineeringChemistry: 0.91× its world share, 6 worksChemistryComputer Science: 0.11× its world share, 4 worksComputer ScienceEnergy: 0.02× its world share, 0 worksEnergyEngineering: 0.11× its world share, 7 worksEngineeringEnvironmental Science: 0.09× its world share, 2 worksEnvironmental ScienceMaterials Science: 0.37× its world share, 5 worksMaterials ScienceMathematics: 0.30× its world share, 2 worksMathematicsPhysics and Astronomy: 0.11× its world share, 1 worksPhysics and AstronomyDentistry: 0.14× its world share, 0 worksDentistryHealth Professions: 0.17× its world share, 2 worksHealth ProfessionsMedicine: 2.39× its world share, 188 worksMedicineNursing: 0.55× its world share, 1 worksNursingVeterinary: 1.12× its world share, 1 worksVeterinaryArts and Humanities: 0.03× its world share, 0 worksArts and HumanitiesBusiness, Management and Accounting: 0.01× its world share, 0 worksBusiness, Management…Decision Sciences: 0.15× its world share, 1 worksDecision SciencesEconomics, Econometrics and Finance: 0.36× its world share, 3 worksEconomics, Econometr…Psychology: 0.35× its world share, 4 worksPsychologySocial Sciences: 0.03× its world share, 2 worksSocial Sciences1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Immunology and Microbiology, 7.5×. Every wedge is a field page.

All 25 fields, with their numbers
  1. Immunology and Microbiology7.51×31 works
  2. Biochemistry, Genetics and Molecular Biology6.03×131 works
  3. Pharmacology, Toxicology and Pharmaceutics3.98×6 works
  4. Medicine2.39×188 works
  5. Neuroscience1.69×11 works
  6. Veterinary1.12×1 works
  7. Chemistry0.91×6 works
  8. Nursing0.55×1 works
  9. Materials Science0.37×5 works
  10. Economics, Econometrics and Finance0.36×3 works
  11. Psychology0.35×4 works
  12. Mathematics0.30×2 works
  13. Health Professions0.17×2 works
  14. Decision Sciences0.15×1 works
  15. Dentistry0.14×0 works
  16. Chemical Engineering0.12×0 works
  17. Computer Science0.11×4 works
  18. Engineering0.11×7 works
  19. Physics and Astronomy0.11×1 works
  20. Agricultural and Biological Sciences0.10×2 works
  21. Environmental Science0.09×2 works
  22. Arts and Humanities0.03×0 works
  23. Social Sciences0.03×2 works
  24. Energy0.02×0 works
  25. Business, Management and Accounting0.01×0 works

Who are the top researchers at Io Therapeutics (United States)?

Ranked on the quality score, Martin E. Sanders, Joann Peters and Rosh Chandraratna lead among researchers whose main affiliation is Io Therapeutics (United States).

  1. 1 Martin E. Sanders United States · #1,027,117 worldwide 7.4k citations · 126 works
  2. 2 Joann Peters United States · #1,901,042 worldwide 287 citations · 16 works
  3. 3 Rosh Chandraratna United States · #5,588,369 worldwide 254 citations · 15 works
  4. 4 Roy Jobson United States · #6,594,339 worldwide 6 citations · 36 works
All ranked researchers at Io Therapeutics (United States)

What are the most cited papers from Io Therapeutics (United States)?

The most cited paper from Io Therapeutics (United States) is "ISCEV Standard for full-field clinical electroretinography (2015 update)" (Daphne L. McCulloch, Michael F. Marmor, Mitchell Brigell et al., 2014), with 1,329 citations. Next come "Cloned pigs produced by nuclear transfer from adult somatic cells" (1,258) and "Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs" (714).

Most cited papers
#PaperReleasedCitations
1 ISCEV Standard for full-field clinical electroretinography (2015 update) Daphne L. McCulloch, Michael F. Marmor, Mitchell Brigell et al. · Documenta Ophthalmologica Open access 13 Dec 2014 1,329
2 Cloned pigs produced by nuclear transfer from adult somatic cells Irina A. Polejaeva, Shu-Hung Chen, Todd D. Vaught et al. · Nature Sep 2000 1,258
3 Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs Yifan Dai, Todd D. Vaught, Jeremy T. Boone et al. · Nature Biotechnology Mar 2002 714
4 Curcumin Suppresses the Paclitaxel-Induced Nuclear Factor-κB Pathway in Breast Cancer Cells and Inhibits Lung Metastasis of Human Breast Cancer in Nude Mice Bharat Bhushan Aggarwal, Shishir Shishodia, Yasunari Takada et al. · Clinical Cancer Research 15 Oct 2005 583
5 A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality Val Mann, Emma E. Hobson, Baohua Li et al. · Journal of Clinical Investigation Open access Apr 2001 471
All 60 most cited papers, with filters and sorting

Which keywords describe research at Io Therapeutics (United States)?

By fractional works in 2022-now, weighted toward what it does more of than the world: Cancer, Immunotherapy, Cancer Therapy, Tumor Microenvironment, Cancer Immunotherapy, Transcriptional Regulation, Inflammation and Tumor Regression.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in 2022-now in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Cancer43▲ 7.8×36 topics
  2. Inflammation32▲ 3.7×59 topics
  3. Immunotherapy30▲ 10×18 topics
  4. Cancer Therapy28▲ 12×16 topics
  5. Tumor Microenvironment24▲ 13×8 topics
  6. Cancer Immunotherapy24▲ 38×3 topics
  7. Transcriptional Regulation23▲ 34×8 topics
  8. Tumor Regression20▲ 44×2 topics
  9. Breast Cancer19▲ 18×7 topics
  10. Lymphoma17▲ 26×4 topics
  11. Leukemia16▲ 48×2 topics
  12. CAR T Cells16▲ 53×1 topic
  13. Chimeric Antigen Receptor16▲ 53×1 topic
  14. Glycosylation16▲ 35×3 topics
  15. Oxidative Stress15▲ 2.2×38 topics
  16. Monoclonal Antibodies14▲ 39×3 topics
  17. Chemotherapy14▲ 4.8×17 topics
  18. Cell Cycle Control13▲ 95×2 topics
  19. Immunity13▲ 7.9×9 topics
  20. Gene Therapy13▲ 16×6 topics
  21. Metabolism13▲ 5.9×15 topics
  22. Therapeutic Antibodies13▲ 44×2 topics
  23. Antibody Engineering12▲ 56×1 topic
  24. Fc Receptors12▲ 56×1 topic
  25. Metastatic Breast Cancer12▲ 51×2 topics
  26. Innate Immunity12▲ 9.1×9 topics
  27. Epigenetic Regulation12▲ 13×4 topics
  28. CDK4/6 Inhibitors12▲ 99×1 topic
  29. Palbociclib12▲ 99×1 topic
  30. Prognostic Factors11▲ 6.4×13 topics
  31. Angiogenesis11▲ 8.2×14 topics
  32. Biomarkers11▲ 3.9×14 topics
  33. BET Bromodomains10▲ 80×1 topic
  34. PROTACs10▲ 80×1 topic
  35. Targeted Therapy10▲ 11×5 topics
  36. Cell Death10▲ 10.0×6 topics
  37. Cell Proliferation9▲ 26×5 topics
  38. Immune Checkpoint Blockade9▲ 20×1 topic
  39. PD-1 and PD-L19▲ 20×1 topic
  40. Apoptosis8▲ 6.6×16 topics

Which research topics does Io Therapeutics (United States) publish most on?

By volume in 2022-now: CAR-T cell therapy research, Monoclonal and Polyclonal Antibodies Research, Advanced Breast Cancer Therapies and Protein Degradation and Inhibitors.

CAR-T cell therapy research: 16 fractional worksMonoclonal and Polyclonal Antibodies Research: 12 fractional worksAdvanced Breast Cancer T…12Advanced Breast Cancer Therapies: 12 fractional worksProtein Degradation and …10Protein Degradation and Inhibitors: 10 fractional worksCancer Immunotherapy and Biomarkers: 9 fractional worksCancer-related gene regulation: 7 fractional worksCancer, Hypoxia, and Met…6Cancer, Hypoxia, and Metabolism: 6 fractional worksImmune Cell Function and Interaction: 6 fractional worksHER2/EGFR in Cancer Research: 6 fractional worksImmunotherapy and Immune Responses: 6 fractional works
OncologyRadiology, Nuclear Medicine and ImagingPulmonary and Respiratory MedicineMolecular Biology2 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 CAR-T cell therapy research Oncology 16 works
  2. 2 Monoclonal and Polyclonal Antibodies Research Radiology, Nuclear Medicine and Imaging 12 works
  3. 3 Advanced Breast Cancer Therapies Pulmonary and Respiratory Medicine 12 works
  4. 4 Protein Degradation and Inhibitors Molecular Biology 10 works
  5. 5 Cancer Immunotherapy and Biomarkers Oncology 9 works
  6. 6 Cancer-related gene regulation Molecular Biology 7 works
  7. 7 Cancer, Hypoxia, and Metabolism Cancer Research 6 works
  8. 8 Immune Cell Function and Interaction Immunology 6 works
  9. 9 HER2/EGFR in Cancer Research Oncology 6 works
  10. 10 Immunotherapy and Immune Responses Immunology 6 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available44.4%not open55.6%

World: 40% of research is openly available.

with international co-authors30.5%domestic only69.5%

World: 18% is written across borders.

How has Io Therapeutics (United States)'s research output changed?

Output in 2022-2025 was 257% higher than in 2018-2021.

still counting1990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Io Therapeutics (United States) as a percentage of every work published that year, 0.0016% in 2024.

still counting0.0010%0.0020%0.0030%Io Therapeutics (United States)0.0019% in 202519801990200020102020

Fractional works of Io Therapeutics (United States) over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year, against all institutions in the same year.

still counting10%20%Io Therapeutics (United States)11.1% in 2025all institutions10.0% in 20252020

Of each year's output, the share that reached the world's 10% most cited for its field and year. Peak 15.2% in 2021.

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Io Therapeutics (United States) on Science Explorer

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