| 1 |
Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936
Jacques J. M. van Dongen et al. · Leukemia
Open access |
Dec 2003 |
3,072 |
| 2 |
Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study
Ezra E.W. Cohen et al. · The Lancet
Open access113 authors |
30 Nov 2018 |
1,731 |
| 3 |
Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline
Pedro Pimentel‐Nunes et al. · Endoscopy
Open access |
28 Aug 2015 |
1,345 |
| 4 |
Randomized Phase III KEYNOTE-181 Study of Pembrolizumab Versus Chemotherapy in Advanced Esophageal Cancer
Takashi Kojima et al. · Journal of Clinical Oncology
|
7 Oct 2020 |
1,199 |
| 5 |
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease
JJM van Dongen, EA Macintyre, J Gäbert et al. · Leukemia
|
Dec 1999 |
1,174 |
| 6 |
Apixaban for the Treatment of Venous Thromboembolism Associated with Cancer
Giancarlo Agnelli, Cecilia Becattini, Guy Meyer et al. · New England Journal of Medicine
Open access |
29 Mar 2020 |
1,067 |
| 7 |
Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma
Cristina E. Tognon, Stevan R. Knezevich, David George Huntsman et al. · Cancer Cell
Open access |
Nov 2002 |
918 |
| 8 |
Performance measures for lower gastrointestinal endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
Michal Filip Kaminski et al. · Endoscopy
Open access |
7 Mar 2017 |
889 |
| 9 |
Multiple Colorectal Adenomas, Classic Adenomatous Polyposis, and Germ-Line Mutations inMYH
Oliver M. Sieber, Lara Rachel Lipton, Michael Crabtree et al. · New England Journal of Medicine
|
27 Feb 2003 |
865 |
| 10 |
Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline
Ian Mark Gralnek et al. · Endoscopy
Open access |
29 Sep 2015 |
835 |
| 11 |
IBMTR Severity INDEX FOR GRADING ACUTE GRAFT‐VERSUS‐HOST DISEASE: RETROSPECTIVE COMPARISON WITH GLUCKSBERG GRADE
Philip Arthur Rowlings, Donna Przepiorka, John P. Klein et al. · British Journal of Haematology
Open access |
Jun 1997 |
697 |
| 12 |
Papillary cannulation and sphincterotomy techniques at ERCP: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline
Pier Alberto Testoni, Alberto Mariani, Lars Aabakken et al. · Endoscopy
Open access |
14 Jun 2016 |
671 |
| 13 |
2019 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer
Dominique Farge et al. · The Lancet Oncology
Open access |
3 Sep 2019 |
660 |
| 14 |
British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma
Matthew R Banks, David Yates Graham, Marnix Jansen et al. · Gut
Open access |
5 Jul 2019 |
657 |
| 15 |
A “Copernican” Reassessment of the Human Mitochondrial DNA Tree from its Root
Doron M. Behar, Mannis van Oven, Saharon Rosset et al. · The American Journal of Human Genetics
Open access |
Apr 2012 |
559 |
| 16 |
Overall Survival with Pembrolizumab in Early-Stage Triple-Negative Breast Cancer
Peter Schmid et al. · New England Journal of Medicine
Open access |
15 Sep 2024 |
544 |
| 17 |
Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation
Mohamad Mohty et al. · Bone Marrow Transplantation
Open access |
16 May 2016 |
542 |
| 18 |
Trifluridine/tipiracil versus placebo in patients with heavily pretreated metastatic gastric cancer (TAGS): a randomised, double-blind, placebo-controlled, phase 3 trial
Kohei Shitara et al. · The Lancet Oncology
|
21 Oct 2018 |
532 |
| 19 |
36th International Symposium on Intensive Care and Emergency Medicine
R. M. Bateman et al. · Critical Care
Open access2,440 authors |
Apr 2016 |
531 |
| 20 |
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
David V. Conti et al. · Nature Genetics
ReviewOpen access231 authors |
2021 |
511 |
| 21 |
Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study
Brigitta G. Baumert et al. · The Lancet Oncology
Open access |
29 Sep 2016 |
504 |
| 22 |
Colorectal cancer incidence, mortality, and stage distribution in European countries in the colorectal cancer screening era: an international population-based study
Rafael Cardoso et al. · The Lancet Oncology
Open access |
25 May 2021 |
496 |
| 23 |
Medial Meniscus Extrusion on Knee MRI: Is Extent Associated with Severity of Degeneration or Type of Tear?
Christopher R. Costa, William B. Morrison, John A. Carrino · American Journal of Roentgenology
|
Jul 2004 |
480 |
| 24 |
Ibrutinib versus temsirolimus in patients with relapsed or refractory mantle-cell lymphoma: an international, randomised, open-label, phase 3 study
Martin H. Dreyling et al. · The Lancet
Open access |
10 Dec 2015 |
468 |
| 25 |
The Dawn of Human Matrilineal Diversity
Doron M. Behar, Richard Villems, Himla Soodyall et al. · The American Journal of Human Genetics
Open access |
25 Apr 2008 |
465 |
| 26 |
Inflammation in intervertebral disc degeneration and regeneration
Maria Molinos, Catarina Rodrigues Almeida, Joana Caldeira et al. · Journal of The Royal Society Interface
Open access |
11 Feb 2015 |
461 |
| 27 |
Chemotherapy plus Involved-Field Radiation in Early-Stage Hodgkin's Disease
Christophe Fermé et al. · New England Journal of Medicine
Open access |
7 Nov 2007 |
448 |
| 28 |
The genome-wide structure of the Jewish people
Doron M. Behar et al. · Nature
|
8 Jun 2010 |
443 |
| 29 |
AUGMENT: A Phase III Study of Lenalidomide Plus Rituximab Versus Placebo Plus Rituximab in Relapsed or Refractory Indolent Lymphoma
John Paul Leonard et al. · Journal of Clinical Oncology
Open access |
21 Mar 2019 |
433 |
| 30 |
Cross-Validation for Imbalanced Datasets: Avoiding Overoptimistic and Overfitting Approaches [Research Frontier]
Miriam Seoane Santos, Jastin Pompeu Soares, Pedro Henriques Abreu et al. · IEEE Computational Intelligence Magazine
|
15 Oct 2018 |
417 |
| 31 |
A global metagenomic map of urban microbiomes and antimicrobial resistance
David Danko et al. · Cell
Open access679 authors |
26 May 2021 |
405 |
| 32 |
Sentinel European Node Trial (SENT): 3-year results of sentinel node biopsy in oral cancer
Clare Schilling et al. · European Journal of Cancer
|
18 Nov 2015 |
396 |
| 33 |
Cancer cachexia and its pathophysiology: links with sarcopenia, anorexia and asthenia
Sara Peixoto da Silva, Joana Santos, Maria Paula Costa e Silva et al. · Journal of Cachexia Sarcopenia and Muscle
Open access |
6 Mar 2020 |
385 |
| 34 |
The Phylogeography of Brazilian Y-Chromosome Lineages
Denise Carvalho‐Silva, Fabrício Rodrigues dos Santos, Jorge Rocha et al. · The American Journal of Human Genetics
Open access |
2001 |
385 |
| 35 |
Technical aspects of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Technical Guideline – March 2017
Marcin Polkowski, Christian Jenssen, Philip Kaye et al. · Endoscopy
Open access |
12 Sep 2017 |
374 |
| 36 |
Performance measures for upper gastrointestinal endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
Raf Bisschops, Miguel Areia, Emmanuel Coron et al. · Endoscopy
Open access |
22 Aug 2016 |
365 |
| 37 |
Assessing individual interethnic admixture and population substructure using a 48-insertion-deletion (INSEL) ancestry-informative marker (AIM) panel
Ney Pereira Carneiro dos Santos, Elzemar Martins Ribeiro-Rodrigues, Ândrea Kely Campos Ribeiro-dos-Santos et al. · Human Mutation
Open access |
Dec 2009 |
364 |
| 38 |
Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria
Angela R Brooks-Wilson et al. · Journal of Medical Genetics
Open access |
Jul 2004 |
364 |
| 39 |
Personalized therapy in multiple myeloma according to patient age and vulnerability: a report of the European Myeloma Network (EMN)
Antonio Pierangelo Palumbo et al. · Blood
Open access |
14 Aug 2011 |
357 |
| 40 |
Indications, results, and clinical impact of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline – Updated January 2017
Jean‐Marc Dumonceau, Pierre Henri Deprez, Christian Jenssen et al. · Endoscopy
Open access |
16 May 2017 |
351 |
| 41 |
Risk of Stevens-Johnson syndrome and toxic epider mal necrolysis during first weeks of antiepileptic therapy: a case-control study
Berthold Rzany, Osvaldo Correia, Judith Parsells Kelly et al. · The Lancet
|
Jun 1999 |
351 |
| 42 |
The timeline of epigenetic drug discovery: from reality to dreams
Arasu Ganesan, Paola Barbara Arimondo, Marianne G. Rots et al. · Clinical Epigenetics
Open access |
Dec 2019 |
349 |
| 43 |
Divergent clonal selection dominates medulloblastoma at recurrence
A. Sorana Morrissy et al. · Nature
Open access138 authors |
2016 |
349 |
| 44 |
BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing
Enric Domingo, P Laiho, M Ollikainen et al. · Journal of Medical Genetics
Open access |
Sep 2004 |
343 |
| 45 |
Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation
Ana C. Jaleco, Hélia Neves, Erik Hooijberg et al. · The Journal of Experimental Medicine
Open access |
Oct 2001 |
343 |
| 46 |
Primers and protocols for standardized detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin and T cell receptor gene rearrangements and TAL1 deletions as PCR targets Report of the BIOMED-1 CONCERTED ACTION: Investigation of minimal residual disease in acute leukemia
MJ Pongers-Willemse, Taku Seriu, Frank Stolz et al. · Leukemia
|
1999 |
342 |
| 47 |
Some Applications of Fractional Calculus in Engineering
J. A. Tenreiro Machado, Manuel Fernando Silva, Ramiro S. Barbosa et al. · Mathematical Problems in Engineering
Open access |
8 Nov 2009 |
341 |
| 48 |
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations
Timothy Richard Rebbeck et al. · Human Mutation
Open access245 authors |
15 Feb 2018 |
325 |
| 49 |
Genetic and archaeological perspectives on the initial modern human colonization of southern Asia
Paul Mellars, Kevin C. Gori, Martin Carr et al. · Proceedings of the National Academy of Sciences
Open access |
10 Jun 2013 |
310 |
| 50 |
Quantitation of GSTP1 Methylation in Non-neoplastic Prostatic Tissue and Organ-Confined Prostate Adenocarcinoma
Cármen Jerónimo, Henning Usadel, Rui Henrique et al. · JNCI Journal of the National Cancer Institute
Open access |
21 Nov 2001 |
309 |