| 1 |
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination
Nina Gustafsson et al. · Nature Communications
Open access |
18 Sep 2018 |
133 |
| 2 |
Identification of novel quinazoline derivatives as potent antiplasmodial agents
Anne Bouchut, Dante Rotili, Christine Pierrot et al. · European Journal of Medicinal Chemistry
Open access |
17 Oct 2018 |
65 |
| 3 |
CD163+ macrophages monitor enhanced permeability at the blood–dorsal root ganglion barrier
Harald Lund, Matthew A. Hunt, Zerina Kurtović et al. · The Journal of Experimental Medicine
Open access |
28 Nov 2023 |
57 |
| 4 |
First-in-class oral small molecule inhibitor of the tyrosine kinase ROR1 (KAN0439834) induced significant apoptosis of chronic lymphocytic leukemia cells
Mohammad Hojjat‐Farsangi, Amir Hossein Daneshmanesh, Abdul Salam Khan et al. · Leukemia
Open access |
27 Mar 2018 |
54 |
| 5 |
A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib
Amir Hossein Daneshmanesh, Mohammad Hojjat‐Farsangi, Amineh Ghaderi et al. · PLoS ONE
Open access |
Jun 2018 |
45 |
| 6 |
Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signaling in Breast Cancer
Rosaria Benedetti et al. · Cancers
Open access |
16 Dec 2019 |
41 |
| 7 |
ROR1 is Expressed in Diffuse Large B-Cell Lymphoma (DLBCL) and a Small Molecule Inhibitor of ROR1 (KAN0441571C) Induced Apoptosis of Lymphoma Cells
Amineh Ghaderi, Amir Hossein Daneshmanesh, Ali Moshfegh et al. · Biomedicines
Open access |
23 Jun 2020 |
38 |
| 8 |
Fractalkine Signalling (CX3CL1/CX3CR1 Axis) as an Emerging Target in Coronary Artery Disease
Shu Xian Loh, Yasemin Ekinci, Luke Spray et al. · Journal of Clinical Medicine
Open access |
21 Jul 2023 |
31 |
| 9 |
The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation
Aikaterini Gatsiou et al. · Immunity
Open access |
25 Apr 2023 |
25 |
| 10 |
Fluorescence-Based Screening Assays for the NAD+-Dependent Histone Deacetylase smSirt2 from Schistosoma mansoni
Matthias Schiedel, Martin Marek, Julien Lancelot et al. · SLAS DISCOVERY
Open access |
17 Oct 2014 |
24 |
| 11 |
Predicting ROR1/BCL2 combination targeted therapy of small cell carcinoma of the lung
Walter Wang, Konstantin Shilo, Joseph M. Amann et al. · Cell Death and Disease
Open access |
4 Jun 2021 |
22 |
| 12 |
Schistosome Sirtuins as Drug Targets
Julien Lancelot, Alejandro Cabezas‐Cruz, Stéphanie Caby et al. · Future Medicinal Chemistry
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Apr 2015 |
22 |
| 13 |
A ROR1 Small Molecule Inhibitor (KAN0441571C) Induced Significant Apoptosis of Mantle Cell Lymphoma (MCL) Cells
Amineh Ghaderi, Wen Zhong, Mohammad Ali Okhovat et al. · Pharmaceutics
Open access |
20 Oct 2022 |
19 |
| 14 |
Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2
Martin Marek et al. · Cell Reports
Open access |
Dec 2021 |
18 |
| 15 |
A Small Molecule Targeting the Intracellular Tyrosine Kinase Domain of ROR1 (KAN0441571C) Induced Significant Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells
Amineh Ghaderi, Mohammad Ali Okhovat, Jemina Lehto et al. · Pharmaceutics
Open access |
5 Apr 2023 |
15 |
| 16 |
PFKFB3 Inhibition Sensitizes DNA Crosslinking Chemotherapies by Suppressing Fanconi Anemia Repair
Anna Huguet Ninou, Jemina Lehto, Dimitrios Chioureas et al. · Cancers
Open access |
18 Jul 2021 |
13 |
| 17 |
Targeting the Receptor Tyrosine Kinase ROR1 by Small Molecules
Mohammad Hojjat‐Farsangi, Ali Moshfegh, Johan Schultz et al. · Handbook of experimental pharmacology
Book chapter |
2021 |
12 |
| 18 |
A ROR1 small molecule inhibitor (KAN0441571C) induced significant apoptosis of ibrutinib‐resistant ROR1+ CLL cells
Amineh Ghaderi, Mohammad Ali Okhovat, Layung Sekar Sih Wikanthi et al. · eJHaem
Open access |
20 May 2021 |
12 |
| 19 |
Targeting CX3CR1 Suppresses the Fanconi Anemia DNA Repair Pathway and Synergizes with Platinum
Jemina Lehto, Anna Huguet Ninou, Dimitrios Chioureas et al. · Cancers
Open access |
22 Mar 2021 |
8 |
| 20 |
Bugs improve nerve regeneration: fasting-induced, microbiome-derived metabolite enhances peripheral nerve regeneration
Zerina Kurtović, Camilla I. Svensson, Emerson Krock · Signal Transduction and Targeted Therapy
Open access |
5 Oct 2022 |
7 |
| 21 |
5234KAND567, the first selective small molecule CX3CR1 antagonist in clinical development, mediates anti-inflammatory cardioprotective effects in rodent models of atherosclerosis and myocardial infarction
Sally Abdelmoaty, Helen M. Arthur, Ioakim Spyridopoulos et al. · European Heart Journal
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Oct 2019 |
7 |
| 22 |
First-in-Class ROR1 Small Molecule Inhibitor (KAN0439834) Downregulated Wnt-Canonical and Non-Canonical Signaling Pathways and Induced Apoptosis of CLL Cells
Mohammad Hojjat‐Farsangi, Ali Moshfegh, Amir Hossein Daneshmanesh et al. · Blood
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3 Dec 2015 |
6 |
| 23 |
A Small Molecule Antagonist of CX3CR1 (KAND567) Inhibited the Tumor Growth-Promoting Effect of Monocytes in Chronic Lymphocytic Leukemia (CLL)
Wen Zhong, Parviz Kokhaei, Tom A. Mulder et al. · Cancers
Open access |
13 Nov 2024 |
5 |
| 24 |
A network of CD163 + macrophages monitors enhanced permeability at the blood-dorsal root ganglion barrier
Harald Lund, Matthew A. Hunt, Zerina Kurtović et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
27 Mar 2023 |
5 |
| 25 |
circRNA landscape in dorsal root ganglia from mice with collagen antibody-induced arthritis
Zerina Kurtović, Katalin Sándor, Freija ter Heegde et al. · Neurobiology of Pain
Open access |
Aug 2023 |
4 |
| 26 |
First generation of a small chemical molecule ROR1 RTK tyrosine kinase inhibitor
Håkan Mellstedt, Mohammad Hojjat‐Farsangi, Amir Hossein Daneshmanesh et al. · Annals of Oncology
Open access |
Oct 2016 |
3 |
| 27 |
Phosphorylation of Receptor Tyrosine Kinase ROR1 At Tyrosine 641, 646 and Serine 652 residues Might Be of Importance for the Survival of CLL Leukemic Cells
Mohammad Hojjat‐Farsangi, Amir Hossein Daneshmanesh, Martin Norin et al. · Blood
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16 Nov 2012 |
2 |
| 28 |
Inhibition of fractalkine signalling in patients with acute myocardial infarction - First results from the FRACTAL trial
Su Peng Loh, Yakup Ekinci, Karim Bennaceur et al. · European Heart Journal
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Oct 2024 |
1 |
| 29 |
First-in-Class Oral Small Molecule Against the Tyrosine Kinase ROR1 (KAN0439834) Induced Significant Apoptosis of Chronic Lymphocytic Leukemia Cells
Mohammad Hojjat‐Farsangi, Amir Hossein Daneshmanesh, Fariba Mozaffari et al. · Blood
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7 Dec 2017 |
1 |
| 30 |
Fractalkine Inhibition in Acute Myocardial Infarction leads to reduced intramyocardial haemorrhage
Su Peng Loh, Yakup Ekinci, Karim Bennaceur et al. · European Heart Journal
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Oct 2024 |
0 |