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Most cited papers from Karolinska Institutet

What are the most cited papers from Karolinska Institutet?

The most cited paper from Karolinska Institutet is "Features and development of Coot" (Paul Emsley, Bernhard Lohkamp, William G. Scott et al., 2010), with 30,245 citations. Next come "International Physical Activity Questionnaire: 12-Country Reliability and Validity" (22,204) and "Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement" (18,014).

Showing 50 of 60 papers. Every paper with more than 4,639 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Features and development of Coot Paul Emsley, Bernhard Lohkamp, William G. Scott et al. · Acta Crystallographica Section D Biological Crystallography Open access 23 Mar 2010 30,245
2 International Physical Activity Questionnaire: 12-Country Reliability and Validity Cora L. Craig, Alison L. Marshall, MICHAEL SJ??STR??M et al. · Medicine & Science in Sports & Exercise Aug 2003 22,204
3 Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement Massimo Dominici, Katarina Le Blanc, Ingo Mueller et al. · Cytotherapy 2006 18,014
4 Tissue-based map of the human proteome Mathias Uhlén et al. · Science Open access 22 Jan 2015 16,343
5 Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance Anna-Pelagia Magiorakos, Arjun Srinivasan, Roberta B. Carey et al. · Clinical Microbiology and Infection Open access 7 May 2011 14,554
6 Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010 Rafael Lozano et al. · The Lancet Open access191 authors Dec 2012 14,344
7 Sarcopenia: revised European consensus on definition and diagnosis Alfonso José Cruz-Jentoft et al. · Age and Ageing Open access 24 Sep 2018 14,151
8 A New Depression Scale Designed to be Sensitive to Change Stuart Montgomery, Marie Åsberg · The British Journal of Psychiatry Apr 1979 14,132
9 Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013 Marie Ng et al. · The Lancet Open access140 authors 28 May 2014 12,158
10 Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Clotilde Théry et al. · Journal of Extracellular Vesicles Open access382 authors 23 Nov 2018 11,535
11 MultiQC: summarize analysis results for multiple tools and samples in a single report Philip Ewels, Måns Magnusson, Sverker Lundin et al. · Bioinformatics Open access 16 Jun 2016 11,105
12 2018 ESC/ESH Guidelines for the management of arterial hypertension Bryan Williams et al. · European Heart Journal Open access211 authors 25 Aug 2018 10,602
13 Analysis of protein-coding genetic variation in 60,706 humans Monkol Lek et al. · Nature Open access Aug 2016 10,439
14 The mutational constraint spectrum quantified from variation in 141,456 humans Konrad J. Karczewski et al. · Nature Open access177 authors 27 May 2020 10,422
15 CHARMM: The biomolecular simulation program Bernard R. Brooks et al. · Journal of Computational Chemistry Open access 14 May 2009 9,331
16 Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 Christopher J L Murray et al. · The Lancet Open access362 authors Dec 2012 9,055
17 Inflammation, Atherosclerosis, and Coronary Artery Disease Göran K. Hansson · New England Journal of Medicine 20 Apr 2005 8,822
18 Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 Theo Vos et al. · The Lancet Open access358 authors Dec 2012 8,461
19 Biological insights from 108 schizophrenia-associated genetic loci Stephan Ripke et al. · Nature Open access297 authors Jul 2014 8,181
20 Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 Mohammad Hossein Forouzanfar et al. · The Lancet Open access654 authors Oct 2016 7,829
21 Geant4 developments and applications John E. Allison et al. · IEEE Transactions on Nuclear Science Open access Feb 2006 7,047
22 Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 Lorenzo Galluzzi et al. · Cell Death and Differentiation Open access169 authors 23 Jan 2018 6,760
23 Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke Werner Hacke, Markku Kaste, Erich Bluhmki et al. · New England Journal of Medicine Open access 24 Sep 2008 6,735
24 Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 Theo Vos et al. · The Lancet Open access679 authors 7 Jun 2015 6,558
25 Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015 Christina Fitzmaurice et al. · JAMA Oncology Open access185 authors 5 Dec 2016 6,333
26 Neuroinflammation in Alzheimer's disease Michael Thomas Heneka et al. · The Lancet Neurology Open access 16 Mar 2015 6,318
27 ILAE Official Report: A practical clinical definition of epilepsy Robert S. Fisher, Carlos Alberto Acevedo, Alexis A. Arzimanoglou et al. · Epilepsia Open access Apr 2014 6,110
28 Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science Emily Alexandra Holmes et al. · The Lancet Psychiatry Open access 15 Apr 2020 6,092
29 Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy Open access2,467 authors 2 Jan 2016 6,023
30 EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update Josef S Smolen et al. · Annals of the Rheumatic Diseases Open access 6 Mar 2017 5,808
31 Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors Bertrand Routy et al. · Science 2 Nov 2017 5,679
32 European Position Paper on Rhinosinusitis and Nasal Polyps 2020 W.J. Fokkens et al. · Rhinology Journal Open access148 authors Feb 2020 5,610
33 HLH‐2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis Jan‐Inge Henter, AnnaCarin Horne, Maurizio Aricò et al. · Pediatric Blood & Cancer 25 Aug 2006 5,452
34 Alternative isoform regulation in human tissue transcriptomes Eric T. Wang, Rickard Sandberg, Shujun J. Luo et al. · Nature Open access Nov 2008 5,451
35 Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol Björn Dahlöf, Richard B. Devereux, Sverre Erik Kjeldsen et al. · The Lancet Mar 2002 5,432
36 Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus Michelle Petri et al. · Arthritis & Rheumatism Open access 2 May 2012 5,385
37 Global prevalence of dementia: a Delphi consensus study Cleusa P. Ferri, Martin James Prince, Carol Brayne et al. · The Lancet Open access Dec 2005 5,347
38 Tumour exosome integrins determine organotropic metastasis Ayuko Hoshino et al. · Nature Open access 28 Oct 2015 5,240
39 Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies Chetan Bettegowda et al. · Science Translational Medicine Open access 19 Feb 2014 5,211
40 External review and validation of the Swedish national inpatient register Jonas Filip Ludvigsson, Eva Andersson, Anders Ekbom et al. · BMC Public Health Open access 9 Jun 2011 5,148
41 The nuclear RNase III Drosha initiates microRNA processing Yoontae Lee, Chiyoung Ahn, Jinju Han et al. · Nature Sep 2003 5,144
42 Common polygenic variation contributes to risk of schizophrenia and bipolar disorder Shaun Purcell et al. · Nature Open access Jul 2009 5,082
43 Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non‐surgical patients Sam Schulman, Clive Kearon · Journal of Thrombosis and Haemostasis Open access Apr 2005 5,063
44 ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology Ingrid Eileen Scheffer, Samuel Frank Berkovic, Giuseppe Capovilla et al. · Epilepsia Open access 8 Mar 2017 5,051
45 Mild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment Bengt G. Winblad et al. · Journal of Internal Medicine Open access 20 Aug 2004 5,036
46 International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma S. Vincent Rajkumar et al. · The Lancet Oncology Open access 26 Oct 2014 5,031
47 Gastric cancer Elizabeth Catherine Smyth, Magnus Nilsson, Heike Irmgard Grabsch et al. · The Lancet Aug 2020 5,024
48 The global prevalence of dementia: A systematic review and metaanalysis Martin James Prince, Renata Bryce, Emiliano Albanese et al. · Alzheimer s & Dementia ReviewOpen access 2013 4,986
49 Genetic studies of body mass index yield new insights for obesity biology The LifeLines Cohort Study et al. · Nature Open access487 authors 10 Feb 2015 4,954
50 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD Francesco Cosentino et al. · European Heart Journal Open access172 authors 31 Aug 2019 4,930

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.